Independent research fellowships leading to tenured positions at the John Innes Centre. Repost = nice. Thank you very much!!!

"Jane Goodall, Eminent Primatologist Who Chronicled the Lives of Chimps, Dies at 91" [gift link, free to read] www.nytimes.com/2025/10/01/o...

Dr. Meghan Koch from @fredhutch.org has discovered a biological mechanism sprung in the first week of life that trains a mouse pup’s #ImmuneSystem to tolerate harmless gut bugs and new foods. ⚗️ Abstract: https://bit.ly/4nt6qGh 📰 Press release: https://bit.ly/46N7vBY

Despite These Times...my department is hiring! I really like my department, we have a good mix of disciplines and organisms and we're really low-drama. We also get pizza at faculty meeting. So if you're a computational and structural biologist, join us! 🧪 jobs.rutgers.edu/postings/260...

Our story describing the Panoptes bacterial immune defense system is now finally peer-reviewed and published today! www.nature.com/articles/s41...

Very happy to share some more good news. Our collaboration with Jeffrey Boyd's lab is now published at J Inorganic Biochemistry! Here, Jeff found that iron limitation reprograms S. aureus metabolism towards fermentation. We're grateful to be part of this study. www.sciencedirect.com/science/arti...

Come and work with me and @ariannebabina.bsky.social on #Streptomyces evolution and antibiotic production Origins of a tangled bank: Adaptation and evolution in antibiotic-producing Streptomyces www.gla.ac.uk/postgraduate... please repost

New in JB: DiMaggio, Yeo & Brinsmade show a link between nucleotide metabolism and the activity of the Sae two component regulatory system via SaeS kinase activity and membrane integrity in S. aureus journals.asm.org/doi/10.1128/... @asm.org #JBacteriology

'With the discovery of riboregulation, this puzzling situation recently changed profoundly for some of these non-canonical RBPs (...) This review will build on textbook features of classical RBPs and further aims to broaden the perspective of biologically meaningful RNA-protein interactions.'

A cyclic di-GMP phosphodiesterase in the VSP-2 island of Vibrio cholerae is regulated by zinc and quorum sensing in mBio from Chris Waters, Thomas O'Halloran journals.asm.org/doi/10.1128/...

Hugely important study- and other analyses have also picked this up

Here we go! I broiled the tops because who doesn't love a little char? The purples turned white and the blacks turned green after cooking. Still gorgeous. And the filling was... just right?!

The whole idea of a selected publications list is like a foreign language to me

any day can be #caturday when you need it to be

They've lost the 9yos

As I said a couple of months ago, things which increase the productivity of the solution factory often also increase the productivity of the problem factory.

Exciting postdoc opportunity with a fab PI in beautiful Basel

"Pain only hurts."

And then Schulman ends the list with this. He’s telling the world he doesn’t understand science without saying he doesn’t understand science. “we still don't have the cure for cancer or Alzheimer's” How naive. How uninformed this is. These diseases are blindingly complex! Progress has been huge.

We're hiring! 5 tenure track assistant professors. 2 #microbiology, 2 #Evolution, 1 #biologicalclocks jobs.sciencecareers.org/job/675062/f...

Former president was decent actually - at least all interactions I had access to. Cared. Honest. The blood thirst willing to throw good people to volcano is pretty abhorrent tbf.

Next up, a req to acknowledge how SARS-Cov2 feels about being vaccinated against

It is not normal in a "free" country to be constantly wondering if you are going to be targeted by a government action. This is the opposite of freedom.

The healthcare systems across rural America are also absolutely dependent on H1-B holders. It is hard to attract surgeons and specialists to many places.

Both bioRxiv Founders came to the US on H-1Bs

had to read the article to understand wtf was going on here which is that Meta is literally feeding Instagram pictures parents took of their teenage daughters to middle aged men as ads for Threads

Replacing “duration of status”, eg while enrolled in graduate studies no matter how long it takes, with a fixed term. Note that most US biomed grad programs run average time to PHD of 5-6 years, not four.

Yup. This was me 10 years ago.

Immigrants, particularly on H1Bs, are the lifeblood of American innovation. If you wanted to hurt US competitiveness in the next century, I can think of few more effective ways than a move like this Even when found illegal, the mere intent will have irreparably harmed our future

BDH2-driven lysosome-to-mitochondria iron transfer shapes ferroptosis vulnerability of the melanoma cell states | Nature Metabolism share.google/FvSVVwZxdNPt...

Any academic folks on H1B visas (even with stamps in passports) please get legal advice from your University attorneys before leaving the US.

Our new preprint is up! This is the main postdoc work of @wiesner-t.bsky.social focusing on exocytosis along the axon shaft and its regulation by the sub membrane actin-spectrin scaffold: www.biorxiv.org/content/10.1... Read the thread below for a summary of our findings 🧵1/11

ADD YOUR THOUGHTS ON LIMITING STUDENT VISA TO FOUR YEARS Comment period ends September 29th www.federalregister.gov/documents/20... 1/2

To "accelerate high-impact, curiosity-led research and innovation, and to facilitate breakthroughs" - let me tell you my students using genAI are NOT curious and what it is accelerated so far is lying, cheating and data fabrication

this is cool

Good grief

You like phages ? In this publication, we use metaHiC and our new version of the MetaTOR pipeline to challenge the traditional view of phages with a narrow host range. @rkoszul.bsky.social @natmicrobiol.nature.com @cnrs.fr @institutpasteur.bsky.social www.nature.com/articles/s41...

Alternatively you can whale whale

Stabilizing effect of amino acids on protein and colloidal dispersions | Nature share.google/XDdrRpb7R2F2...

Very interesting new @wbickmor.bsky.social commentary on the mechanistic mystery that is very distal enhancer-promoter interactions www.nature.com/articles/s41...

The buff-tip moth (Phalera bucephala) has mastered a very particular kind of camouflage. When they close their wings up, they resemble a broken twig. Native to large parts of Europe, there's regional pattern variation that reflects the local tree species. This one best resembles birch twigs?

Heads up: ignore samtools dot org, similarly minimap2 dot com and likely others. It's owned by a known phishing site and while the binaries they offer look valid currently (but note they may be serving us different binaries to others), that could change. Ie: it's not us (Samtools team)! Be warned

JB Editor's Choice: Richardson & Pascal do a deep dive into the many iterations of bacterial two-hybrid systems and their uses in bacteria - a must read for those looking at protein-protein interactions. journals.asm.org/doi/10.1128/... @asm.org #JBacteriology

Really impressed by the technical relevance of advice I am getting on BlueSky for an arcane issue in molecular microbiology. Props to this boutique social media platform.

Anytime you tickle the immune system, there is a chance for things to go wrong. This includes vaccination. Oc ones odds are much worse w/the pathogens themselves. But a lot of people have an invincibility complex & convince themselves inaction somehow takes them out of the gamble. Wrong.

Oh to be a little Tardigrade scratching its back on a bubble. 🫧🐻🧪

Tried to open office door w/car button. How's your day going?

'Mechanistically, oxPLs bound and inhibited AKT, potentiating the methionine cycle and the activity of the epigenetic writer EZH2. EZH2 epigenetically dampened the pluripotent anti-inflammatory cytokine IL-10, contributing to the death of the host.' #Immunology www.cell.com/immunity/abs...

New academic faculty posts available at Imperial College London! Assistant/Associate Professors in Life Sciences. Please apply and/or circulate details! www.imperial.ac.uk/jobs/search-...