Clearly, We've Lost Control.

Our work characterizing enteroendocrine cell (EEC) differentiation trajectories and the underlying GRNs in pluripotent stem cell-derived human intestinal organoids has been published today in @biologyopen.bsky.social. Thanks to all. doi.org/10.1242/bio.... #organoids; #EEC; #Enteroendocrine cells

Symposium to Celebrate the career of Francois Guillemot at @ the Francis Crick Institute in London. Thanks for all Francois. Was great to catch up with all the friends.

Only one week left! We’ve already received many exciting applications and are expecting more. Maybe yours!

2/2 m - Most EEC cells are specified during development through similar differentiation trajectories as observed in the adult intestine. - Crypt-villus organization is not essential for EEC formation. - Novel GRNs are identified governing human EEC differentiation in human intestinal organoids.

1/2. I am pleased to announce that the preprint of our latest study characterizing mouse and human EEC development is now on BioRxiv. A great collaboration with the @molinalab.bsky.social and Maxime Mahe (not on bluesky) www.biorxiv.org/cgi/content/...

We are hiring PhD students! Interested in #ComputationalBiology and #MachineLearning? Join our lab at the @IGBMC! #PhDposition https://euraxess.ec.europa.eu/site/search?text=Nacho+Molina+IGBMC&antibot_key=f6b99bce6cc751c6716e2f0b89773e15

The unintended (?) consequence of the tariffs is that the reduced consumption it'll drive will probably significantly reduce greenhouse gas emissions

Important diabetes news. Unfortunately, while VX264 (Vertex's encapsulated stem cell derived islet product) has been safe in patients, the company has discontinued the trial due to insufficient function of the cells. investors.vrtx.com/news-release...

@novonordiskcom.bsky.social licenses a P2 ready triple agonist #obesity #diabetrs #MASH www.novonordisk.com/content/nnco...

NEW: Elon Musk’s X has suspended accounts of Turkish opposition groups, suppressing footage of anti-government protests. So, best we share all the footage we can here! This was last night’s massive demo against Erdogan’s government, which follows the arrest of his rival Ekrem İmamoğlu. 🇹🇷 #Turkey

I guess this means I’m not going to the US for the next four years - at least.

Symposium on ‘Enhancer Sequences’ at beautiful @collegedefrance.bsky.social in Paris, by April 11th. Open and free, no registration. Come to relax listening to facts #TherapeuticEffects #VillageGauloix Final programme below. Tell your friends! 🙏🤘

Yesterday's article in Le Monde regarding #StandUpforScience and the events planned tomorrow in France. Here is the link to the English version, though partially paywalled. www.lemonde.fr/en/science/a... @standupforscience.bsky.social @standupforscifr.bsky.social

We're hiring! The Development & Stem Cells department at @igbmc.bsky.social, Strasbourg 🇫🇷 is recruiting a group leader working in cell & developmental biology. Our Integrated Structural Biology department also has an open call. More details below! + contact me for informal enquiries #sciencejobs

But: this isn’t a meeting that went badly for Zelenskyy. It’s a meeting that went horrifically for Americans: the Trump admin is isolated in its support for Russia here, as we saw just earlier this week when it took its place among Russia’s other client states to vote against Ukrainian sovereignty

After World War I, Germany had to fork over billions to cover damages. After World War II, Japan was forced to pay reparations. But with Ukraine, Trump is flipping history upside down by demanding that the invaded, not the invader, pay up. www.nytimes.com/2025/02/27/u...

Our job posting for 1 or more PDF positions in Vancouver Canada is now live here: tinyurl.com/4mrjw3m2 Please share/repost and apply soon!

Paper out !!🥳big thanks to all authors @marliesoomen.bsky.social @diego-rt.bsky.social @kaessmannlab.bsky.social @jonathangoeke.bsky.social @lorenzamottes.bsky.social & 'bluesky-less' Lots of interesting new TE (& genes) biology Data fully browsable💻 👉 embryo.helmholtz-munich.de/shiny_embryo/

I am devastated by so many irresponsable decisions www.bbc.com/news/article...

Mikael Chetboun & François Pattou comment on: Long-term outcomes and challenges of #islet #transplantation in type 1 #diabetes thelancet.com/journals/lan... #T1D

Gene editing technology began by people studying salt marshes. Ozempic began by folks studying the venom of Gila Monsters. Support for basic science has empowered us to understand our world. Tethering it to applications health has transformed and saved countless lives.

I do hope that President Trump and Mr Musk realize that US biomedical research is still one of our strengths and only possible because of NIH funding

While it may be true, as claimed by Mr. Bannon, that in the IT industry H1b visas have been abused to bring in cheap labor, in biomedical research progress can only be made by recruitment of foreign fellows. There simply are not a sufficient pool of US born Ph.D.s left who want to work in academia

Friday Lectures – Giacomo Cavalli Join us on Friday, 7th February at 3pm for a talk by Giacomo Cavalli, expert in Polycomb regulation and 3D genome architecture. He’ll explore how these mechanisms affect epigenetic inheritance and cancer development. Don’t miss it! #Epigenetics #Genomics #Cancer

📣 Hiring, please forward widely!! Two postdoc openings to work on genomics of diabetes 1. Computational regulatory genomics/statistical genetics. 2. Experimental cell-based modeling DM if interested @crg.eu shorturl.at/O3wMi shorturl.at/ieyZy

We have room and $ for postdoctoral fellows to join our team in beautiful Vancouver 🇨🇦. Get in touch if interested.

Application deadline is get closer - make sure you do not miss this exciting EMBO workshop on liver and pancreatic biology and disease 😉 meetings.embo.org/event/25-liv...

📢 We are recruiting group leaders! We seek researchers who address fundamental questions in biology, including the development, the function, and the dynamics of complex biological systems. APPLY before March 30th 2025 👉 www.ibdm.univ-amu.fr/we-are-recru... #ScienceCareers #Marseille

Stéphane Viville, responsable de l’unité de génétique de l’infertilité des Hôpitaux universitaires de Strasbourg, fait partie du comité exécutif de la European society for Human reproduction and embryology, la plus grosse société savante en médecine de la reproduction.

New week, new #EISG2025 star speakers! On session 4 -The islet cell in T1D & treatment strategies- we will hear from: - Carmella Evans-Molina (@cevansmo.bsky.social ) - Roberto Mallone (@institutcochin.bsky.social ) - Teresa Rodrigez-Calvo (@teresarc.bsky.social ) Register now at eisg2025.se

The Nazis think this was a Nazi salute, but, hey, what would they know?

Nothing but a grift to the fossil fuel industry. Below a picture from a near-shore array of 89 4.3 MW windmills arranged in a hexagon, 3 miles offshore. I took the first pic 2 yrs ago, you have to strain your eyes to see them from shore. Right now they provide clean energy to 500,000 households ...

Job alert heads-up! 😃 We will soon be opening a Group Leader position in the Department of Development and Stem Cells in IGBMC, near Strasbourg, France. The official call will appear soon. In the meantime, those interested are welcome to contact me for details!