Jinyi Tang, PhD, received an NIHK99/R00 grant! The award was issued for Jinyi's work developing mucosal vaccines, which he and the @jie-immunology.bsky.social lab have shown to offer additional protection against COVID-19. Read more: immunology.virginia.edu/jtang_k99/

Excited to share our new findings: Severe respiratory viral infections like COVID-19 and flu can accelerate lung cancer development. Our study establishes a direct causal link, highlighting the urgent need for long-term cancer surveillance in COVID-19 survivors. doi.org/10.1101/2025...

HHS Secretary Robert F. Kennedy Jr. threatened to bar government scientists from publishing in major medical journals, saying on a podcast that three top journals were “corrupt” and influenced by pharmaceutical companies.

SIS 2025 registration ends next Monday. We still have a few seats available. Please join us! @uvaimmunology.bsky.social

SIS 2025 early registration and abstract due today. Please join us! @uvaimmunology.bsky.social

Abstract submission due in 1 week on April. 21st. #SIS2025. Please join Drs. Merad, Mathis and Kipnis and many more on the beautiful UVA campus. www.immunology.virginia.edu/sis2025/

Wow. #HandsOff rally in St. Paul, Minnesota is massive!

How I will remember April Fools' Day 2025. Reckless. My heart is out for these dedicated folks at NIH, FDA and CDC www.statnews.com/2025/04/01/h...

By attacking science: We are less safe because science informs national security and medical care. We are less prosperous because science drives innovation and economic benefit. We are less free because science and democracy depend on the liberty to ask questions, and seek and share knowledge.

We are glad to make to the round of 16 #STATMadness2025. Our work has discovered an aberrant immune-epithelial niche underlying severe long COVID. www.nature.com/articles/s41... Please keep supporting us by voting for the University of Virginia team.

Join us on the topic of an aberrant immune-epithelial niche driving respiratory long COVID at the ATS online journal club. Please register below here. site.thoracic.org/events/an-ab...

If any of this seems normal, you need to open your eyes. profkap.substack.com/p/never-norm...

We are glad to make to the round of 16 #STATMadness2025. Our work has discovered an aberrant immune-epithelial niche underlying severe long COVID. www.nature.com/articles/s41... Please keep supporting us by voting for the University of Virginia team.

Join us with Drs. Mathis, Kipnis and Merad for #SIS2025 at the beautiful UVA campus in Charlottesville! It’s an affordable meeting with an outstanding speaker lineup. Enjoy the superb local history, food, wineries, events, and scenic views. immunology.virginia.edu/sis2025/

Five years ago on March 11, the World Health Organization officially declared COVID-19 a pandemic.

Our 100th episode is out! 🎊 Nobel Laureate Dr. Peter Doherty (@pcdoherty.bsky.social) discusses his career, from studying sheep as a veterinarian to discovering the mechanisms of #Tcell antigen recognition. 🐑 Listen now: bit.ly/3FxLX1X

To vote, please select the “University of Virginia” team. We need your vote daily 😊 🙏.

We made it to the Round 2 🎉. Please keep supporting us 🙏.

Using a comparative analyses of human and mice PASCs, Xiaoqin Wei and Jie Sun’s group report that severe COVID-19 causes disruption of peroxisomes in macs, which are essential for lung repair, regulation of inflam and chronic fibrosis @jie-immunology.bsky.social [3/n] www.science.org/doi/10.1126/...

On Friday, we Stand Up for Science in locations Nationwide (& internationally!) to support science as a public good that benefits everyone. Join us! Visit www.standupforscience2025.org for more information & other ways to get involved ☀️

So happy to share our latest paper on #AlveolarMacrophage responses to low-dose #LPS led by @pamelialim.bsky.social!AM #innate responses are enhanced by IFN-beta due to low c-Maf and IL-10 expression, with implications for AM responses to respiratory infections and environmental exposure. #ImmunoSky

Increasing evidence for the central role of peroxisomes in antiviral immunity. A new study provides in vivo evidence to support a role for peroxisomes in SARS-COV-2 infection. Kudos to the authors on this important study. www.science.org/doi/10.1126/...

It’s #norovirus week in #ScienceTranslationalMedicine! Two papers show that we can vaccinate against norovirus in older adults and that vaccines have the potential to be broadly protective. Good news for anyone afraid of norovirus (me!). www.science.org/toc/stm/curr...

When vaccination rates fall....... www.latimes.com/opinion/stor...

We are thrilled to share our new manuscript @science.org , in which we uncovers a critical role for macrophage peroxisomes in lung repair after viral infection. Could targeting peroxisomes be the key to mitigating long COVID?! www.science.org/doi/10.1126/...

#InterferonFriendOrFoe?! Joe Sun, Xiaoqin Wei &co show @science.org that lung macrophage peroxisomes instruct repair programs after virus infections favoring AT2 cell renewal & recovery! IFNgamma drives pexophagy, increasing mitochondrial ROS & activating inflammasomes driving KRT8 cells & fibrosis!

The proposed prevention and potential therapy is 4-phenylbutyrate (4-PBA) which could be a repurposed drug currently used for treating heritable, rare, urea cycle disorders

Another helpful graphic for the mechanism identified in this important paper

Just published @science.org A basis—lung inflammation—for #LongCovid (PASC) in the experimental model, and a potential therapy [driven by alveolar macrophages and loss of their peroxisomes (Figure)] www.science.org/doi/10.1126/... www.science.org/doi/10.1126/...

New @science.org The disappearance of butterflies at a "catastrophic rate" in the United States www.science.org/doi/10.1126/... www.science.org/doi/10.1126/... www.washingtonpost.com/climate-envi...

We are excited that our paper on the immune mechanisms of long COVID is selected for the #STATMadness  @statnews. Help us to go to round 2! 🙏  statnews.com/feature/stat-madness/bracket-voting-now-open

Too dramatic this week at UVA with two “shelter in place” orders! Today, we are so glad to have the chance to finally celebrate colleagues’ big achievement.

We’re thrilled to announce that the 12th Southeastern Immunology Symposium (SIS) website is now live, and registration is open! Join us at the beautiful UVA campus on Jun. 6, 7 this summer. Secure your spot today! immunology.virginia.edu/sis2025/

now more than ever

Top read articles in 2024: SARS-CoV-2 Spike protein triggers gut impairment since mucosal barrier to innermost layers: From basic science to clinical relevance; mucosalimmunology.org/article/S193...

Speaker line up for #EMBOTissueImmunity to take place in Basel 🇨🇭 26-29 August 2025. Come join @maurogaya.bsky.social and I for some fantastic #immunology along the Rhine! Please share this invitation - we hope you will join us. Registrations will be open soon.