Check out the largest collection of C elegans missense variants to date: - 12k unique & viable strains sequenced - 20 million variants - 21k genes - integrated database with ClinVar for translation to humans Out now at @lsajournal.org www.life-science-alliance.org/content/9/6/...

When do PIs, especially with teaching commitments, ever find time to read papers to keep up with the field? Do you set aside specific times of the week, use the daily commute on bus/train, or have come up with some other approach? Asking for a friend...

I got to see a former trainee defend her thesis @rockefeller.edu! Marwa Saad worked with me at MIT during my postdoc and gave me this fabulous mug (still have it!) Then we both ended up at Rockefeller! She was a grad student w with @danmucida.bsky.social and I’m here at @rupress.org Congrats!!

Important pivot underway by my colleagues @embopress.org to embrace evolutionary biology, diverse species, and non-reductionist approaches to biological systems. Bravo!

Why did Nature expand? It is unacceptable that an author might find a non-Nature journal as a fit for their work: "Awe noticed that there is growth in some fields that we don’t think we can support effectively within the range of journals that we currently have." -Executive VP, Journals

Writing my recent editorial was secretly just an excuse to read a bunch of Stephen Jay Gould. I was led there by Howard Browman in his editorial. Browman frames question of negative data as a deeply philosophical issue of what motivates scientists to communicate their findings.

the most annoying shift in my academic career

Really cool work here!! Congrats @emery-lab.bsky.social

Editorial by me, in our March issue! Negative results are a thorny issue in essentially all fields of scientific research, and deserve a renewed look by authors and editors 👇

It’s finally out! Together with @embopress.org and @reviewcommons.org, we conducted a structured side-by-side comparison of human peer review and our AI scientific review (see thread 👇👇👇🔥).

Required reading, folks 👇

🎉🎉🎉

Sooo happy to share our new paper in @nature.com “CLCC1 promotes hepatic neutral lipid flux and nuclear pore complex assembly.” A terrific collaboration with @arrudalab.bsky.social, led by co–first authors Alyssa Mathiowetz and Emily Maymand. www.nature.com/articles/s41...

Congrats @sudha-kumari.bsky.social on this nice paper out in @emboreports.org 🥳

This is also something that NIH Director Bhattacharya loves to trumpet (as if no other NIH officials before him recognized this problem...)

!!! www.theatlantic.com/ideas/2026/0...

Nature group: "DO YOU WANT MORE JOURNALS???" Researchers: "um... not... really? no there are alread-" Nature: "YESSS HERE YOU GO MORE JOURNALSSSS!!" group.springernature.com/gp/group/med... @springernature.com

We are pleased to be a media partner for the @embo.org @embl.org Symposium - Microtubules: from atoms to complex systems Abstract submission: 11 Mar 2026 Registration (On-site): 6 May 2026 Registration (Virtual): 10 Jun 2026 bit.ly/4jDTuMH #EESMicrotubules

Minor point: Not defending the publisher and certainly not the authors here, but it is common for the journal to convey the authors’ assertions about the paper, if any.

Thanks Prof Baumelle for the summary of this really exhaustive look at a new post-translational modification of Syk and how it affects phagocytosis!

Super nice work covering stops, starts, and reversals in axonal traffic. Congrats!

🔬Join our #ReproductionMS seminar with Dr. @maikbischoff.bsky.social on "Coiling a Duct: How Mesenchymal Cells Sculpt Male Reproductive Organ Architecture" this Wednesday, 11 February 12pm CET. DM for Zoom details.

Hello epithelial mechanics fans!! I’m Juanma @juanmagararc.bsky.social 👋 I work on cell mechanics (see celldynamicslab.com) and use Flipper-TR FLIM to probe membrane biophysics in cells. Join me on this tour about Flipper: what it measures, strengths, advice, cool case studies, and cute drawings!

One of the spammy things you see repeatedly as a journal editor are invitations to publish conference proceedings. They get to have a paper and the targeted journal collects an APC. Like this one. Is this real? Who knows

👀

Sir Francis Bacon griping about publication bias in 1605 😍 From Steven Jay Gould’s collection of essays Dinosaur in a Haystack

Wiley: "We’re supporting responsible research assessment practices" onlinelibrary.wiley.com/journal/1520... Also Wiley: "Prove that your article is a good fit for this journal 😉😉😉😉😉 by citing at least two of our articles in your manuscript before we will even consider reviewing it" 🤡

You can submit proposals for scientific sessions at CellBio aka ASCB until Feb 22nd. This includes minisymposa, special interest sessions workshops. If you thought CellBio should improve, now is your chance to make that happen 👇 www.ascb.org/cellbio2026-...

keeping up (barely 🥴) with my fave immunologists!! First: Sometimes macrophages nibble (trogocytosis) and sometimes they chomp (phagocytosis). @fletcherlabucb.bsky.social nicely show how target cell mechanical properties bias macrophage behavior. Beautiful work! doi.org/10.1038/s415...

Updating a 56 year-old JCB paper with digitized videos from 16 mm film 😍. Well done first author Tom Pollard!!

A pleasure to work with these authors on this study! Check out very nice imaging showing ER-microtubule interactions in regenerating axons.

Two new 🔥pre-prints 🔥 TODAY by us & @pwoakes.bsky.social @myosincity.bsky.social change the way we think about the septin cytoskeleton Septins buffer mechanical stress on actin and membranes! Septins are like intermediate filaments www.biorxiv.org/content/10.6... www.biorxiv.org/content/10.6...

🚨 We are hiring TWO postdocs to join the Cell Migration Lab (cellmig.org) 🇫🇮 as part of the new Centre of Excellence in Immune–Endothelial Interfaces (IMMENs). Join us to decode immune regulation & develop next-gen imaging tools! 🧪🔬 Details in thread 🧵👇 #ScienceSky #Postdoc #AcademicJobs Please RT🫶

📰 #PressRelease: Researchers in Japan have discovered that amyloid-β deposits disrupt the formation of the placenta & may therefore contribute to the development of #preeclampsia during #pregnancy. www.eurekalert.org/news-release... In @lsajournal.org: www.life-science-alliance.org/content/9/4/...

Still no idea wtf the Vault evolved to do, but it can be made useful!! Glad to see this out finally! “A genetically encoded device for transcriptome storage in mammalian cells” www.science.org/doi/10.1126/...

I need to admit that @epimechfc.bsky.social is one of best #SCiComm in this era!👍

Poll of two postdocs I happened to sit with for lunch yesterday (at Rockefeller U): -Editor at @science.org offered guidance to authors on how to respond to reviewer comments. -Editors at @nature.com did NOT. Just sent a form email inviting revisions.

Fantastic work on autophagy in flies from Juhasz and Szabo labs!! Super happy see this work out from world experts in this area.

To decide whether to select a 3D cell migration assay for your application and how to analyze the resulting data, read: ... about the 3D cell-migration assay and other migration assays here: www.nature.com/articles/s41... For data analysis, read this review paper: www.nature.com/articles/s41...

We at @lsajournal.org have discussed doing calls for papers/special issues. Some great journals like @jcellsci.bsky.social have them. But our leadership was VERY clear: MDPI, Frontiers, and their ilk have so sullied this publication mechanism that no one wanted to go there. The concept is tainted.

interesting

🚨Introducing DevBioConnect ‼️
Developmental Biology launches a new author webinar series showcasing recently published research, presented by the authors themselves 🗓️ Jan 13 • Feb 10 • Mar 10, 2026
⏰ 11am–12pm CST
📄 See flyer for details
#DevBio #DevelopmentalBiology

Too many fabulous seminars here at @rockefeller.edu On Tuesday @deepakkrish.bsky.social (formerly @prakashlab.bsky.social, now @fletcherlabucb.bsky.social) showed gorgeous loricate choanoflagellates!! Difficult but rewarding to study how these critters deftly manipulate materials at the mesoscale.

Surprised (pleasantly!!) that total science research posts on X were only a wee but more than twice the research posts on Bluesky! Great news given the huge disparity in total volume between the two platforms.

Interested in the MBL Physiology Course in Woods Hole and want to learn more before you apply? Join myself and Cliff at our Virtual Open House TOMORROW 2–3 PM ET. You will hear what the course experience is like and get all your questions answered. Register/Join: princeton.zoom.us/j/97673682905

Neat!

Giving the gift of negative data 🥰 Since I joined @lsajournal.org I have handled several stellar manuscripts that report null results. These papers do very well and reviewers almost always appreciate them! Thanks @rockefeller.edu news team for the article! www.rockefeller.edu/news/38829-t...

Vote for JCB’s cover of the year! Explore 12 breathtaking images submitted by our talented authors and pick a favorite. Voting closes on Wednesday, December 31! 👉 www.surveymonkey.com/r/JCB2025Cov... #ScienceArt

I just finished my 28th yr of teaching grad compbio. Following the inevitable trend, a 3rd of the course is now Deep Learning (DL). One activity we did was a deep dive into the AlphaGenome pre-print (www.biorxiv.org/content/10.1...). Question is, how do we evaluate it as a science paper? 1/n

With a smaller, somewhat fraught #cellbio2025 behind us I am nevertheless still inspired and amazed at this community. Curious to hear others’ impressions!!