Safe to say that Day 1 of 'Cellular mechanisms driven by phase separation' has been a success so far, with lots of great talks, including a keynote by Karla Neugebauer, and plenty of opportunities to socialise and get to know each other 🙌🏼 #EESPhaseSeparation @embo.org @embl.org

New preprint! Cell division has to happen at the right place but how Archaea pick that place is unknown. We now identified a three-protein system, Dip, that positions the divisome at midcell in H. volcanii and is broadly conserved across Archaea. A thread 🧵 www.biorxiv.org/content/10.6...

Two of our lab members are at the EMBO | EMBL Symposium on cellular mechanisms driven by phase separation this week! 🙌 Come and visit their posters: 📌 Mariya → Poster #114 📌 Joachim → Poster #54 #EESPhaseSeparation @events.embl.org @embo.org @embl.org

A new preprint from the lab showing how Atg1 regulates the BLTP Atg2. This study was spearheaded by Sonja Achleitner and Susanna Tulli, involving a fantastic collaboration with @ainaraclaveras.bsky.social and Gerhard Hummer. @maxperutzlabs.ac.at @viennabiocenter.bsky.social @maxplanck.bsky.social

Our ULK1–MTFR1L paper is now officially in @jcellsci.bsky.social, a good moment to reshare it. 🎉 The work identifies MTFR1L as a key coordinator of mitochondrial fission, mitophagy initiation and apoptosis. 👉 Paper: doi.org/10.1242/jcs....

Congratulations to our SFB 1381 PIs Claudine Kraft and Carola Hunte and their teams - great story on the link between the mitochondrial fission and autophagy machinery!

🚨 Paper Alert! In this new work published in @jcellsci.bsky.social we shift our focus on MTFR1L and the feedback loop linking mitochondrial fission, mitophagy and apoptosis. MTFR1L emerges as a critical coordinator of the fission and autophagy machinery. 🔗Find the paper here: doi.org/10.1242/jcs....

New pre-print from the lab! We show that the subtilase SBT12a is essential for symbiosome stabilization in Medicago. Using HUNTER proteomics, we even got some of its substrates. Have a look. www.biorxiv.org/content/10.6...

What a blast! 🎉 Our International Symposium last week gathered 27 world class speakers and over 200 participants. From electrifying plenary talks to vibrant poster session chats, the energy was palpable and the atmosphere truly unforgettable. A massive thank you to all speakers and attendees!

That's a wrap on the 2nd International Symposium organized by @sfb1381.bsky.social in Freiburg! 🎉 Three days of great talks, fascinating science, and wonderful people. Loved being part of it. Huge thanks for the organisation!

We are excited to share our new preprint which is now available to read on biorXiv: doi.org/10.64898/202... 🎉🎉🎉

If you are at #CellBio2025, head over NOW to room 108 to hear about CIBSS and the Clusters of Excellence @immunosens.bsky.social and @cecad.bsky.social. We are looking forward to meet you!

Online now - the Review " #Autophagy regulation by phase separation, avidity, and wetting" from @wilflinglab.bsky.social, @kraftlabfr.bsky.social and co. #BiomolecularCondensates #PhaseSeparation #Wetting #Avidity #Theraeputics Read it here: authors.elsevier.com/sd/article/S...

Physical principles have redefined our understanding of autophagy. In our new @cp-trendsbiochem.bsky.social review, we discuss how phase separation, avidity, and wetting shape autophagy at the molecular level. Great collaboration with @wilflinglab.bsky.social www.cell.com/trends/bioch...

Congratulations! Our SFB 1381 Principal Investigator Claudine Kraft has been awarded an esteemed ERC Synergy Grant, along with her partners in Vienna and Berkeley.

Vier #ERCSynergyGrants für Forschende der #UniFreiburg. Insgesamt werden die vier Projekte durch den @erc.europa.eu mit rund 41 Millionen Euro über sechs Jahre gefördert; die #UniversitätFreiburg erhält davon gut neun Mio Euro. ➡️ Mehr zu den geförderten Projekten hier: ufr.link/erc-synergy-grant-25

Congratulations! Claudine Kraft @kraftlabfr.bsky.social receives a prestigious ERC Synergy Grant – to find out why some protein #aggregates can be cleared by #autophagy and others not. She and her partners will harness this knowledge to improve autophagy in #ageing & #disease. 🔗  kurzlinks.de/50j8

Fantastic teamwork with @kraftlabfr.bsky.social and @jimhurley.bsky.social! Looking forward to exciting discoveries ahead. Many thanks to @erc.europa.eu for funding our proposal. @univie.ac.at @maxperutzlabs.ac.at @viennabiocenter.bsky.social

Thrilled to join you and Claudine to study the cell's own version of Banksy's self-shredding artwork!

New #CORDIS article on work by Claudine Kraft @kraftlabfr.bsky.social l "Autophagy: the cell’s waste disposal system" - work was result of @erc.europa.eu LS1 project "AutoClean" #H2020 #EUfunded cordis.europa.eu/article/id/4...

Back from the 8th NAS Conference in Sånga Säby, and what a wonderful experience it was! Christoph and Franzi represented the lab, and as a cherry on top, Chris won an award for his talk 🎉 Huge thanks to the NAS for organising and always creating such a warm community atmosphere!

The future of @cibss.bsky.social @uni-freiburg.de is about teamwork, curiosity, and collaboration across disciplines. We are thrilled to be in this together @kraftlabfr.bsky.social @archaellum.bsky.social @kleinevehnlab.bsky.social !

New leadership for #CIBSS! Welcome Sonja-Verena Albers as new spokesperson & congrats to Claudine Kraft on her confirmation. Together with Jürgen Kleine-Vehn, they’ll lead CIBSS into its #NextChapter – following Wolfgang Driever & Carola Hunte. More info: kurzlinks.de/fkv4

And it's out! I'm thrilled to share our new paper (Adriaenssens et al., Nat Cell Biol 2025). This paper describes a new mechanism for the initiation of autophagosome biogenesis. We found that this WIPI-ATG13-driven pathway is preferentially used by a group of transmembrane autophagy receptors.

🎓✨ Huge congratulations to Saskia, an amazing PhD student who just successfully defended her thesis! The flower crown toss might just become our new lab tradition! @uni-freiburg.de

🧬 Excited to share this new publication! A collaborative effort within @sfb1381.bsky.social exploring the intersection of immunology and autophagy. 📖 Read it here: www.embopress.org/doi/full/10....

Die @dfg.de fördert drei Graduiertenkollegs „FORSCALE“, „Analysis nichtlinearer PDG“ und „ProtPath“ an der #UniFreiburg. Dieser Erfolg stärkt die #Spitzenforschung und #Nachwuchsförderung in Freiburg in #Forstwissenschaften, #Biochemie und #Mathematik. ➡️ ufr.link/dfg-grk-2025 #DFG

Excited to share our newly published work on ATG9A — this time focusing on its role at the lysosome. Discover how ARFIP2 and ATG9A coordinate PI4P regulation during lysosomal repair! Congrats to all the authors, and special thanks to @stedet.bsky.social & @satooze.bsky.social !! 📜 bit.ly/43EbrDo

Celebrating our successful new excellence cluster #FutureForests @uni-freiburg.de. Thanks @dfg.de, this will enable us to substantially invest in exciting and much-needed research for the next 7 years - predicting and transforming forest systems in a changing climate uni-freiburg.de/futureforest...

🎉Ab 1. Januar 2026 fördert die @dfg.de (#DFG) zwei #Exzellenzcluster der #UniFreiburg. Der bisherige #Exzellenzcluster @cibss.bsky.social wird weitere sieben Jahre fortgesetzt. Zudem startet der neue Exzellenzcluster #FutureForests. ufr.link/exzellenzclu...

Thrilled to announce that our Cluster of Excellence CIBSS – Centre for Integrative Biological Signalling Studies @cibss.bsky.social will continue to receive funding for another seven years! We’re happy to be part of such a great team!

We are thrilled to have just found out: CIBSS has secured continued funding under the #ExcellenceStrategy! This major boost will enable us to accelerate our research into biological signalling and lay the groundwork for next-generation insights from 2026 to 2032!

From May 5–8, 2025, the Cryo EM facility of #unifreiburg hosted an introductory workshop supported by SFB 1381 to learn how to access and use this cutting-edge technology. Hands-on sessions covered everything from sample prep to data analysis. Big thanks to the facility!

📆Join us this Wednesday, May 14th at 10:00 AM EST (NY Time) as Drs. Licheva, Babic, and Mancilla present their recent work: "Phase separation of initiation hubs on cargo is a trigger switch for selective autophagy" 🔗Zoom Info: Contact [email protected] We look forward to seeing you there!

Our 'SFB 1381's Female Minds' series has officially kicked off! Visit our website to read the first feature, introducing our SFB 1381 Principal Investigator Claudine Kraft: www.sfb1381.uni-freiburg.de/sfb-1381s-fe... @kraftlabfr.bsky.social

Women in Autophagy is hosting their 6th Annual Symposium Webinar. Highly recommended for anyone interested in autophagy. #Autophagy #WomenInScience

Happy to have participated in the #FCQC2025 in Frankfurt last week. Great to connect with others in the field and hear about exciting work. Thanks to the organizers for putting it together.

🤩 2nd day of #FCQC2025 conference in Frankfurt was filled with inspiring lectures, vibrant discussions, great posters and a lot of joy of meeting colleagues from all over the world! A huge thanks to all organizers & supporters! @goetheuni.bsky.social @sfb1177.bsky.social @proxidrugs.bsky.social

Great kick off of our #FCQC2025! Looking forward to the next days full of inspiring sessions, meaningful conversations, and exciting new connections 🙌 @sfb1177.bsky.social @enablefrankfurt.bsky.social @proxidrugs.bsky.social @goetheuni.bsky.social

If you are interested in apoptosis, metabolism, cell death and autophagy, join the Swiss Apoptosis & Autophagy Meeting 2025 on September 4-5, at the Institute of Tissue Medicine and Pathology in Bern. Submit your abstract until June 20: meetings.ls2.ch/sa2m-2025 ‼️ Registration is free for all‼️

🔄 Repost because the previous link was broken! To degrade or not to degrade! We put together an Autophagic Punctum with @wilflinglab.bsky.social on our latest paper, take a look if you're interested! 🔗 www.tandfonline.com/doi/full/10....

To degrade or not to degrade! We put together an Autophagic Punctum with @wilflinglab.bsky.social on our latest paper, take a look if you're interested! 🔗 www.tandfonline.com/doi/full/10....

It’s #InternationalWomensDay tomorrow! We took the occasion to talk to molecular biologist & CIBSS leadership team member @kraftlabfr.bsky.social about #Equality, #CultureChange and the power of mentoring and supportive networks in science. 📖 Read the full interview here: kurzlinks.de/ndwd

Just wrapped up the 2025 lab retreat! Great discussions, great company, and a fondue night in Basel to celebrate! 🫕✨

💫NEW: Kraft, Wilfling & co show that low-affinity cargo–receptor interactions promote #autophagy receptor mobility and condensation of the scaffold protein Atg11 to trigger initiation hub and phagophore formation. www.nature.com/articles/s41...

If you are wondering if you should come to the Keystone #autophagy meeting this year, the answer is – yes! Of course you should! www.keystonesymposia.org/conferences/...

We are pleased to introduce the 4th Frankfurt Conference on Quality Control in Life Processes organized by @idikic.bsky.social, Maike Windbergs & Volker Dötsch. The program is now available — more updates to come. fcqc.de @proxidrugs.bsky.social @sfb1177.bsky.social #FCQC2025

Big thanks to Chunmei Chang and Yi Lu for their insightful "News and Views" article on our recent paper! We really appreciate the way they explained our findings. 📰 You can read it here: www.nature.com/articles/s41... And thanks, @naturecellbiology.bsky.social , for highlighting our work!

Proud to share our latest work with @jessenlab.bsky.social ! We optimized a method to purify polyphosphate in human cells. The paper reviews critical steps in protocols, shares physiological insights, and yes – we’ve got NMR snapshots of mammalian polyP! Read more: doi.org/10.1016/j.ym... #polyP