#NewResearch The Toxoplasma gondii effector TgROP1 mimics host factors to bind VAPA/B, thereby establishing parasite–host ER contact sites. #MicroSky 🦠 www.nature.com/articles/s41...

🚨 New work out from the Pernas Lab. Congratulations to my labmate Chahat Mehra!! Host organelle - pathogen membrane contact sites!! ER edition! rdcu.be/eRKUM

Applications are open for the Postdoctoral Enrichment Program (PDEP)—supporting postdocs as they advance cutting-edge research and build thriving scientific careers. Learn more & apply: bwfund.org/pdep #bwfpdep

Supervisors who invest in positive mentoring relationships with their PhD candidates also reap the benefits for their own research go.nature.com/4hriohE

Last year, we helped 100 students save $31K in grad school app fees, giving students from underserved communities the freedom to apply widely. This year we lost 16 partners = $8.2K setback = 110 fewer dreams. 🎓 You can change that. 💸 Donate to open 110 new doors. givebutter.com/supportCL

NEXT WEEK: Applying to grad programs in the sciences? 🧬✨ Hear directly from university administrators about the key do’s and don’ts for a standout application. Join our Faculty Panel for practical advice & answers to your questions. 📅 10/7, 11am ET 📍 Register: www.eventbrite.com/e/faculty-pa...

Ribonucleotide incorporation into mitochondrial DNA drives inflammation www.nature.com/articles/s41... Congratulations to the Langer lab @mpiage.bsky.social, Amir, and the rest of the team!

Our new collection offers cell biologists practical, expert-driven guidance and best practices in the design, execution, and analysis of experiments, and the subsequent communication of their results to their peers. 👉 rupress.org/jcb/collecti... #Reproducibility

Join me in donating to ABRCMS. For many of us early in our careers (and for many of us now), this is THE conference. Let’s make sure future generations get the same experience. I was told if each poster judge donated $25, their goal would be quickly met, but I think we can do better! 🙏🏾💪🏾

Quite a week for #lipidtime: phenomenal study using bifunctional lipid probes to quantify intracellular lipid transport from @nadlerlab.bsky.social and colleagues is now out @nature.com! www.nature.com/articles/s41...

📣 Are you a undergraduate student, graduate student, or early-career professional in the biomedical sciences looking to transition from academia into industry? Join us for: Thriving in Biotech – Building Bridges, Breaking Barriers. www.scientistsinsolidarity.org/conference

🎓 Planning to apply to STEM graduate programs? Join us for our webinar: “Applying to Grad Programs in STEM” on Thursday, 8/28 at 5.30pm ET. Gain key insights on: ✅ Grad school application timeline ✅ How to choose the right program 🔗 Register: eventbrite.com/e/gsmi-2025-...

New work out of the Pernas Lab!! Congratulations to my lab mates, especially Tania for spearheading this great story!! 🎉 Mitochondria protect against an intracellular pathogen by restricting access to folate | Science www.science.org/doi/10.1126/...

Great perspective piece out of my PhD lab! 👇🏽

RNA N-glycosylation enables immune evasion and homeostatic efferocytosis by chemically caging acp3U. Excited to report this work lead by Vinnie @vinnieviruses.bsky.social and in collaboration with @vijayrathinam.bsky.social in @nature.com www.nature.com/articles/s41...

A story from LAist (local LA public radio) about the freezing of funds. I have had my grant frozen, so has nearly everyone else i know. laist.com/news/climate...

If you're a UCLA researcher (PI, grad student, etc) with an NSF, NIH or other suddenly suspended grant, please email or DM me. I'm trying to confirm what the suspension letters say and how extensive the NIH suspensions are. Email: Mikhail at calmatters dot org

Multiple federal agencies are suspending research funding at UCLA over allegations it didn’t properly deal with antisemitism on campus. scim.ag/4lbLAcx

The NSF grants suspended at UCLA total $179M, half of which was still outstanding: CAREER grants, a major math institute, and basic science research and training of all types. More at grant-witness.us/posts/UCLA-n..., thanks to GW member Mally Shan, with grant-level details in our database.

As Requested - A Starter Pack of PIs in Biology (or adjacent) fields who are recruiting POSTDOCS! Please don't hesitate to reach out if you wish to be added! go.bsky.app/4gbXXR3

Gray flower. #FluorescenceFriday

We are excited to have our new paper out: Tethering of the pathogen sensor caspase-4 to the endomembrane damage sensor galectin-8 poises the host to rapidly detect pathogens that breach the endolysosomal network. www.cell.com/cell-reports... #innate_immunity #inflammasome #celldeath #immunoSky 1/2

NEW ISSUE! Discussing skeletal muscle adaptations and post-exertional malaise in long COVID, miRNAS in beta cell inflammation, mitochondria as pathogen sensors, lipid droplets in skeletal muscle metabolism, modulating ferroptosis against cancer and much more! (1/2) www.cell.com/issue/S1043-...

BWF is proud to announce the 2025 recipients of its Postdoctoral Diversity Enrichment Program (PDEP), which provides critical support to postdoctoral researchers pursuing careers in biomedical and medical research. www.bwfund.org/news/bwf-ann... #bwfpdep

How innate immunity starts? Early embryos eliminate bacterial infections by epithelial phagocytosis, a conserved process from zebrafish to human embryos. Check our story: www.cell.com/cell-host-mi...

May the anti-ICE movement continue to spread nationwide! This is the Los Angeles spirit your news broadcast isn’t showing…

Law enforcement throwing tear gas at people… protesting against law enforcement. 🙊🙉🙈 ICE out of LA! 📢⚖️

Every scientist should discuss the consequences of the NIH and NSF grant terminations and delays and failure to fund at their home institution at the end of a talk or seminar. Even if a scientist’s own funding is not threatened, I GUARANTEE there is someone at their institution affected.

New work @harvard by Miguel Gonzalez-Lozano @harperlabhms.bsky.social & @ernstschmid.bsky.social in Johannes Walter lab charts structural interactome of endosomes. #XL-MS #Alphafold Funded by @asapresearch.parkinsonsroadmap.org & NIH. Science continues-despite attacks www.nature.com/articles/s41...

“I was scared, panicked, but at the same time, fascinated. Those organisms can live in my intestine, and they are so resistant!” Kevin Liévano-Romero abandoned a vet career in Colombia to move to the US, where he studies feared but fascinating creatures https://go.nature.com/3FjMBjZ

I was PREP cohort #1. Today was the LAST UNC PREP symposium. Watching Dr. Joshua Hall, who was the Director my year and 11 years after, give the closing keynote was 😭🥹 But what was built cannot be undone. Our community is strong and all 137 of us are not going anywhere 💪🏾

🚨For scientists in the Boston area!

🚨🚨 Alarming NSF policy update By accepting an NSF award, an institution now must say it's: 1. Not engaging in boycotts of Israel (yes really) 2. Not advancing or promoting DEI in violation of anti-discrimination laws Announced via a footnote today: nsf-gov-resources.nsf.gov/files/gc1-ma...

Just got news that @hhmi.org decided to not review Hanna Gray fellowship applications. I am sorry but that’s fucked up. People spent months working in those. So now you disadvantaged these candidates even more. They could have used the time to advance their research instead.

Academic workers across the country are calling 📞 Legislators to ask them to sign on to bipartisan letters ✉️ in support of robust NIH funding and opposing the 15% indirect cost caps. Take 5 minutes to call your legislators today. Deadline is May 19th. docs.google.com/document/d/1...

‘Devastating:’ Chan Zuckerberg charity slashes funding for more Bay Area nonprofits

It's not just Columbia, it's not just DEI, and it's not just biomedical research: Trump's war on universities has frozen crucial science at institutions like Princeton, Cornell, Northwestern, and more. Our @nature.com team spoke to some of the affected scientists: www.nature.com/articles/d41...

Microbial pathogens, and their ability to manipulate processes in our cells, will never cease to amaze me. #FluorescenceFriday

Disappointed, but not surprised.

this is how it's done.

Appreciating images of my infected cells this morning and trying to find some peace as science continues to be under attack. 🙂🫠 #FluorescenceFriday

Along with the firings of up to 1300 co-workers this week and the removals of several institute leaders, NIH employees are dealing with another blow from the administration of President Donald Trump: a mandate to eliminate $2.6 billion in contracts. scim.ag/43XU1nd

Finally got the notice. Very sad day for the MOSAIC program that supported some of the most amazing scientists I know, as well as some of the awesome people on my lab.

Today was yet another sad day for science. All U-RISE training programs, including the one at SJSU, got stop work orders. We've had a version of this program at SJSU for 30+ yrs. Devastating for the students who got their stipends & tuition pulled w no notice & for the future of science 🧪 1/

Countdown to an epic new pre-print. Mitochondria are cells within our cells. They need the same core activities - replication, transcription, translation. How do cells enable these diverse activities in both compartments? We uncover an unexpected + broad strategy with ancient origins. Stay tuned!

Training grants being heavily affected. Truly destroying the future of science. www.nature.com/articles/d41...

Getting reports of some sound problems with our Twitch livestream. Here's another stream while we sort out some technical difficulties! www.youtube.com/watch?v=eemj...

Welcome to the Bluesky account for Stand Up for Science 2025! Keep an eye on this space for updates, event information, and ways to get involved. We can't wait to see everyone #standupforscience2025 on March 7th, both in DC and locations nationwide! #scienceforall #sciencenotsilence

"We at @nature.com denounce this assault on science. And we encourage the global research community, wherever they can, to voice their opposition." +1 to this. Overall a very good read to help the science community focus our energy 🧪 www.nature.com/articles/d41...