New results! Mechanistic corticostriatal circuit model predicts learning-dependent fMRI dynamics and individual reward bias in humans doi.org/10.64898/202... #neuroscience #neuroblox

Computational models are a key part of science but discovering new ones is hard! DataDIVER discovers concise models from data, which surface new mechanistic ideas and clear predictions for future experiments From Google Deepmind Neuroscience Lab + collaborators www.biorxiv.org/content/10.6...

My review with @caterinagratton.bsky.social is (apparently) open access for those who couldn't see it before: www.annualreviews.org/content/jour... We discuss individual differences in brain network organization and how to home in on and talk about commonalities in the face of such differences

🚀 We’re hiring - Join our lab 🚀 🔍 Hiring: PhD (75% TV-L) & Postdoc (100% TV-L) 🧠 fMRI, VR, EEG, modelling We combine a range of cognitive neuroscience methods to study flexible behaviour. 📅 Start: Feb 2026 or later | ⏳ Apply by Nov 3! More details: tinyurl.com/ms3a9ajt #CognitiveNeuroscience

** We have up to TWO funded PhD positions available in our lab!! Apply below to find new ways to enhance memory👇 Pls retweet ** Deadline: 2nd December 1. Cross-species closed-loopTMR: tinyurl.com/bddu4tp6 2. TUS and TMR in humans: tinyurl.com/jjws5ctj Happy to chat to interested applicants.

The @crick.ac.uk is recruiting Early Career Group Leaders - Lab set-up, research costs, salaries for up to 5 researchers - Support for up to 12 years - Access to our core facilities - Competitive salary - Fantastic colleagues - All areas of biology Deadline 27 Nov www.crick.ac.uk/careers-stud...

A core function of cortex is predicting what happens next given the world's state. This recent paper from Oxford shows how cortical layers may use a delay trick to learn to predict. A simple illustration can explain the idea. A🧵with my toy model and notes: #neuroskyence #compneuro #NeuroAI

📣 New preprint from the Braga Lab! 📣 The ventral visual stream for reading converges on the transmodal language network Congrats to Dr. Joe Salvo for this epic set of results Big Q: What brain systems support the translation of writing to concepts and meaning? Thread 🧵 ⬇️

New paper in Imaging Neuroscience by Jingyuan E. Chen, Jonathan R. Polimeni, et al: Differentiating BOLD and non-BOLD signals in fMRI time series using cross-cortical depth delay patterns doi.org/10.1162/IMAG...

We’re looking for a postdoc to join our Max Planck group in Germany some time in 2026. If you have computational and/or neuroimaging expertise, and are interested in questions intersecting perception and cognition, please reach out! I’ll also be happy to chat at the #Bernsteinconference this week.

Our new paper is out now in Neuron! 🎉 With @vaibhavtripathi.bsky.social @maxwellelliott.bsky.social Joanna Ladopoulou, Wendy Sun, Mark Eldaief, and Randy Buckner Paper link: www.sciencedirect.com/science/arti...

Very excited for this year Bernstein! @bernsteinneuro.bsky.social We'll bring a bunch of new work, here's a thread with the summaries. Please check them out if you are interested in (low rank) RNN and distributed computations.

I’m super excited to finally put my recent work with @behrenstimb.bsky.social on bioRxiv, where we develop a new mechanistic theory of how PFC structures adaptive behaviour using attractor dynamics in space and time! www.biorxiv.org/content/10.1...

There is going to be an exiting workshop on advanced fMRI end of October in Erice, Sicily (Italy). The agenda looks just at great as the location. ismrbf.marbilab.eu/events/7-xiv...

does someone good at coding & analysis want to work remotely w/ us in the coming few months (before end of 2025), as a paid consultant? project will be on neurofeedback (fMRI, ECoG, calcium imaging). we'll work towards developing the experiments & analysis pipelines together. if so pls DM me ur CV🧠📈

Run don’t walk to the #Neuro4Pros summer school if it happens again and you’re an early career prof Thanks again for the absolute best time ⭐️ @gunnarblohm.bsky.social @kordinglab.bsky.social @yaelniv.bsky.social @meganakpeters.bsky.social @patrickmineault.bsky.social, and Hannah Bayer

For the laminauts. @layerfmri.bsky.social

What started as a journal club on layer decoding turned into a project thanks to @karolisdegutis.bsky.social. Our preprint challenges a widespread assumption in the field: MVPA is not immune to vascular confounds in laminar GE-BOLD decoding, as shown using a mechanistic laminar response model.

Happy to see this out: our new preprint shows that laminar GE-BOLD fMRI decoding isn’t immune to vascular draining biases. Simulations reveal false positives due to multivariate signal spread across layers, but oversampling + deconvolution can (sometimes) improve specificity.

Having fun facilitating this amazing group of young Profs at the #Neuro4Pros workshop with @kordinglab.bsky.social and @meganakpeters.bsky.social, @yaelniv.bsky.social, and Hannah Bayer. Watch out world: this is the next generation of leaders! compneurosci.com/Neuro4Pros/i...

We’re hiring! 🥳fully funded PhD and postdoc positions in human cognitive neuroscience @mpicybernetics.bsky.social M/EEG and brain stimulation methods to study timing/ prediction/ attention/ oscillations tinyurl.com/5dku4du9 @timingresforum.bsky.social @gtc-tuebingen.bsky.social please repost 🙏

Datasets like NSD & THINGS offer rich stimuli but often test a single task. After great conversations at #CCN2025 on multi-task studies & generalization in brains & models, I thought I would repost our perspective for those interested in this topic. We need multiple tasks!👉 doi.org/10.1038/s415...

Now out with a really cool additional finding: doi.org/10.1016/j.ne...

The lateral prefrontal cortex 🧠— which we think of as critical for goal driven behavior + is a target for psychiatric treatments— is fundamentally different in individuals relative to the group averages we’ve often studied. 👇see preprint and thread, led by Zach Ladwig #neuroskyence #PsychSciSky

🚨 New Preprint 🚨 Targeting intracranial electrical stimulation (ES) to network regions defined within individuals causes network-level effects By Cyr et al. *** Q: Can we use individualized network maps from precision fMRI to modulate a targeted network via intracranial ES? A: Yes! 🧵:

Thanks to all (co)authors & reviewers for their contribution to this study on #layer specific changes in #sensory #cortex across the #lifespan in #humans & #mice now out in @natneuro.nature.com Here is a short summary of our findings 1/6

I still get chills Meet Mike *30+ years severe depression *first hospitalized @ 13y *20 meds *3 rounds of ECT *2 near-fatal suicide attempts Mike felt joy for the first time in decades after we turned on his new brain pacemaker or PACE see videos, read paper, follow thread doi.org/10.31234/osf...

“NeuroAI should not remain limited to learning statistical relationships, but should also help in building mechanistic and causal models of neural activity. These models will incorporate biological properties of neural circuits, including cellular characteristics and network properties.” 💯💯💯

1 To predict the behaviour of a primate, would you rather base your guess on a closely related species or one with a similar brain shape? We looked at brains & behaviours of 70 species, you’ll be surprised! 🧵Thread on our new preprint with @r3rt0.bsky.social , doi.org/10.1101/2025...

12 All this suggests that mechanical morphogenesis may be a major 3rd causal determinant of the development and evolution of brain organisation in primates.

I’m happy to share that our manuscript on the cortical depth-dependency of the GE- and SE-BOLD point spread function at 7 Tesla is now available on bioRxiv! www.biorxiv.org/content/10.1...

Just dropped in @natcomms.nature.com: we show that re-engaging a thalamic–ventral tegmental circuit with deep brain stimulation can reignite consciousness in patients with severe brain injury. Work led by Aaron Warren, with @andreashorn.org @foxmdphd.bsky.social @ others! tinyurl.com/4kz8j89b

Evidence for dlPFC contribution to #memory suppression using #TMS! Now accepted @jocn.bsky.social. Great team effort and collaboration with Gesa Hartwigsen’s lab @mpicbs.bsky.social‬. We also had an exemplary experience at the journal with editors @barense.bsky.social‬ & @bradpostle.bsky.social‬.

Excellent piece today in @thetransmitter.bsky.social by @callimcflurry.bsky.social on a paper we’ve discussed at some length here (🧵below); she does a terrific job capturing different reasons to be excited about this work (as well as the controversies). www.thetransmitter.org/emotion-proc...

I’m elated to share our latest publication - out now in @natmentalhealth.nature.com! www.nature.com/articles/s44... - tour de force by @leahbanellis.bsky.social @brainandstomach.bsky.social and the rest of the VMP team!

Trying to train RNNs in a biol plausible (local) way? Well, try our new method using predictive alignment. Paper just out in Nat. Com. Toshitake Asabuki deserves all the credit! www.nature.com/articles/s41...

One of the “golden videos” that I took during my Grass Fellowship @grassfoundation.bsky.social - active sleep in these little guys is so obvious and flamboyant! @mblscience.bsky.social

I wrote an entry on Transformers for the Open Encyclopedia of Cognitive Science (‪@oecs-bot.bsky.social‬). I had to work with a tight word limit, but I hope it's useful as a short introduction for students and researchers who don't work on machine learning: oecs.mit.edu/pub/ppxhxe2b

1/3) This may be a very important paper, it suggests that there are no prediction error encoding neurons in sensory areas of cortex: www.biorxiv.org/content/10.1... I personally am a big fan of the idea that cortical regions (allo and neo) are doing sequence prediction. But... 🧠📈 🧪

This is a nice new study showing the mechanisms why CBV fMRI is so specific to cortical layers: The somatostatin neurons are driving the hemodynamic response at fMRI-typical time scales. By Vo et al, from Seong-Gi Kim's lab. doi.org/10.1038/s414...

Still not using DeepPrep? It’s been downloaded 15k+ times (7k on DockerHub alone) in just 5 months after launch — helping labs speed through fMRI preprocessing 10x faster than conventional pipelines. see doc: deepprep.readthedocs.io/en/latest/

For any postdocs who are are looking to transition to independence and might be keen to join us here at @kingsioppn.bsky.social, King's Prize fellowship applications are open (deadline 27 Nov) 👇 See link for details, and feel free to reach out if you'd like to chat www.kcl.ac.uk/jobs/119505-...

there are many! (from recent OHBM anatomy session slides on PFC)

Unattended working memory items are coded by persistent activity in human medial temporal lobe neurons www.nature.com/articles/s41...

𝗣𝗿𝗲𝗳𝗿𝗼𝗻𝘁𝗮𝗹 𝗰𝗼𝗿𝘁𝗲𝘅 𝗼𝗿𝗴𝗮𝗻𝗶𝘇𝗮𝘁𝗶𝗼𝗻 𝗛𝗶𝗲𝗿𝗮𝗿𝗰𝗵𝘆, 𝗵𝗲𝘁𝗲𝗿𝗮𝗿𝗰𝗵𝘆, 𝗯𝗼𝘁𝗵, 𝗻𝗲𝗶𝘁𝗵𝗲𝗿?? Posting this paper again because it's looking more spectacular than I realized before. #neuroskyence doi.org/10.1016/j.ce...

Stimulating and recording with intracranial electrodes implanted in cortical regions and thalamic nuclei across 4,864 sites in 27 human participants reveals distinct spectral signatures elicited by perturbations of specific brain areas www.nature.com/articles/s41...

1/11 Excited to share our @Naturestudy led by @leonooi.bsky.social @csabaorban.bsky.social @shaoshiz.bsky.social AI performance is known to scale with logarithm of sample size (Kaplan 2020), but in many domains, sample size can be # participants or # measurements... doi.org/10.1038/s415...

Prefrontal axons going to lots of places! doi.org/10.1016/j.ce... #neuroskyence