Let me be clear. As someone who has been professionally involved with the biodefense / biosecurity sector for nearly 20 years, and has worked on biological risk analysis for Covid-19 since early 2020, reducing one's risk of being infected is not health anxiety. It's just smart.

There's always a next one coming. This hell is forever.

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Now the pro-trump crowd will also cancel their subscriptions. But of those of us who cancelled initially, only the ones with the most annoying kids will come back. Do well from the beginning or you'll be attacked from all sides.

WEREWOLVES

Disney learned nothing from Andor.

Actuarial innit. If they don’t cover your disease shot, they’re more likely to have to cover your disease. #vaccineswork

The remarks weren’t “about Charlie Kirk,” they were about how this administration is using Kirk’s death as an excuse to shut down critics … and they responded by proving him completely correct.

Not really an overstatement to say that the test of a free society is whether or not comedians can make fun of the country's leader on TV without repurcussions.

January 22

I don’t know when it’s going to pop for a lot of normies that they are living under an authoritarian regime, but the cancellation of popular TV shows that make fun of the administration might do it www.vulture.com/article/abc-...

I just cancelled my Disney+ suscription. There's a text field when you do that which allows you to explain why you do it. You can do it today and still wach stuff until your yearly plan expires. You can also send the message and then hit renew at the last minute. Probably with a better price too.

This is worth 15 minutes of your time when you have it. My goodness youtu.be/nMyyVaiY4V8

America is so broken.

The UK does a yearly GP patient survey. Results for 2025 show a continuing decline of the health of the general population. All those infections are taking a toll.

I shouldn't be shocked, but I'm still always brought up short to realize how many people think "civility" means "white people speaking in relatively calm voices" no matter what vile shit they say.

Another molnupiravir sequence from Australia showed up today w/extremely strong evidence of positive selection for MOV-induced mutations, a sign the genetic diversity created by MOV is being utilized to the virus's advantage. Similar signals have been in almost every MOV sequence in recent months.

Pivoted so hard they affected the earth's rotation

so donald trump had a stroke right

so many american problems but confident stupidity is up there. bring back pointing and laughing at people who say dumb things with such gumption.

I'm going to keep my mouth shut about the murder of one person and remain very vocal about the genocidal bombing and starvation of tens of thousands of children that our governments are enabling. Basically, the exact opposite of half the people in my feed today.

Academic freedom and the integrity of higher education are almost totally dead in the US. Just like that.

Inded, go in and watch the clip in the tweet that starts with "caught on tape". It reminded me of The Handmaid's Tale. Chilling.

I encourage people to watch this video. The selected footage shows the professor doing nothing even slightly out of line, whereas the student misinterprets the law and hopes to impose her religious beliefs on the material. Administrators caving to this is terrifying.

The term is ethnic cleansing. www.reuters.com/world/middle...

Amid so many awful things in this, the authors attempt to downplay the murder of Palestinian children: “Resulting in 22% of total casualties being children, well under the proportion of children in the population in Gaza.”

V. interesting. The "island of strangers" speech happened serendipitously (in one sense) during a panel survey. Paper uses this natural experiment to see the effect of such migrant-sceptic interventions on individual perceptions and voter intentions. Upshot: it harmed Labour for no obvious benefit.

There's been some speculation about why, despite persistent immune activation, germinal center activity, & overall elevated Ab levels, LC patients here had very low anti-spike Ab titers. I want to highlight one interesting speculative hypothesis & offer another possibility. 1/10

Lethal force against a civilian vessel in international waters is a war crime if not in self-defense. If not in self-defense, only non-lethal actions, such as warning shots or disabling fire, are allowed. "Not yielding to pursuers" or "suspected of carrying drugs" doesn't carry a death sentence.

'The unexpected finding that vaccination-only participants showed superior cross-neutralization compared to individuals with hybrid immunity challenges conventional assumptions about hybrid immunity advantages'. www.medrxiv.org/content/10.1...

New data from the sentinel system in Spain: the percentage of people currently with covid is between 2% (if you look at the proxy) and 4% (if you look at positivity). This wave hasn't been high, but it's lasting a long time: it has infected between 17% and 32% of the population and it's still going.

Study about healthcare consultations in Norway: "Deviations from expected pre-pandemic trends worsened dramatically from 2022, coinciding with the Norwegian government’s lifting of all COVID-19 preventative measures. Increases typically occurred 3–6 months after COVID-19 waves." What a surprise.

"Pat, why do you carry that ridiculous 600mm lens on long hikes?" Buddy, I can see mountains reflected in the eyes of a trailside pika.

Solving the housing affordability problem by removing immigrants may be effective in the same sense that cutting off your arm would be an effective way to lose weight.

Turns out some of the “we want small government” people kiiiinda wanted the government to be just one guy.

It'll always be interesting to me that you can tell exactly when school starts up.

I'm old enough to remember when people said Israel wouldn't bomb a hospital, kill journalists, kill first responders.

We had an agreement called NAFTA. Trump 1.0 blew it up. We negotiated a new agreement with Trump 1.0 called CUSMA (aka USMCA). Trump 2.0 blew it up. Why on Earth would anyone think that a new agreement with a fully fascist Trump 2.0 would provide any stability whatsoever?

1. Biological risk is both multifaceted and additive. Any of the following individual risks would be concerning; when combined, they effectively constitute a powder keg waiting for a spark:

1. 'Overall, our findings raise compelling questions about the potential role of SARS-CoV-2 infection in accelerating or triggering neurodegenerative diseases linked to protein amyloidosis'. An example of such a disease is Parkinson's Disease (PD). pubs.acs.org/doi/10.1021/...

To decide between these claims, everyone will simply apply their best scientific analytical lese to this. That is: which hypothesis means I can still have brunch and also that I don't have to do anything or change anything?

1. 'SARS-CoV-2 is linked to “an unusually high level of ‘indiscriminate’ killing of T cells,” says Leitner, adding that this observation is “reminiscent of” measles, which can cause immune amnesia by depleting memory B cells... www.bmj.com/content/390/...

A common technique of Holocaust deniers is to look up Red Cross statistics for disease in the concentration camps, and insist this proves that Jews and Romani were not deliberately murdered.

This, except: I think covid is endemic now, worldwide. Just like malaria is endemic in Nigeria: 225 million people, 68 million yearly cases, 200k yearly deaths. This hell is here to stay, thinking we're still in a pandemic is unrealistically optimistic.

Fact 2, intake matters. Drinking coffee has real health benefits (who knew?) Drinking alcohol really doesn’t (bummer) Ultra Processed Foods (UPFs) are REALLY bad for you. It goes well beyond being empty calories. 3/

6. As such - and it really is stating the obvious here - ongoing global population infection with SARS-CoV-2 will make the world sicker, through both infection-induced chronic disease and pathogen-pathogen interaction.

Best comment on Jay Bhattacharya that I've read to date.

Motherfucker wrote one sloppy paper in April 2020 and instead of being like oops, shit, my bad, he has kept doubling down until now he's killing most promising medical technology of the past quarter century rather than going to therapy.

Wow I wonder if there’s a common thread.

Will be hard to explain in the future that the US government went antivax, causing a lot of avoidable suffering and death, not in response to any negative incident with vaccines, but to the biggest, fastest, most successful, most impressive vaccine rollout in history.