Conor Browne
@brownecfm.bsky.social
📤 11657
📥 471
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Biorisk analyst | Co-Founder Foundry 42
pinned post!
1. I'm very happy to introduce you all to Foundry 42, the realisation of a concept my co-founders and I have been developing for nearly two years.
5 months ago
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I have no issue with this piece - other than the now-expected omission of the word, 'Covid'. What I find interesting is just how mainstreamed 'brain fog' has become. BBC News - Creatine - can muscle-boosting supplement help with brain fog? - BBC News
www.bbc.co.uk/news/article...
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Creatine - can muscle-boosting supplement help with brain fog?
As its popularity grows, research suggests creatine may also benefit short-term memory, mood and focus.
https://www.bbc.co.uk/news/articles/c2lx7klzvpko?app-referrer=deep-link&app-referrer=deep-link
3 days ago
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Fundamentally, the reason I avoid Covid is because all - all - of the elements of my life that bring me joy and fulfillment rest on my cardiovascular fitness and / or my cognition. I'm not going to risk a virus wrecking that, as I've seen happen to way too many people I know.
5 days ago
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My mother passed away two years ago today. She had a wicked, mischievous sense of humour, prone to extended episodes of the giggles, and a joy in discovering new things or places - which is why I'm sharing this photo of her discovering IG filters for the first time in 2016!
7 days ago
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1. Pandemics shape politics and societies. Collective trauma is a powerful force, as is societal reaction to governmental responses to reduce transmission. This is not controversial; humanity experienced it after The Spanish Flu.
8 days ago
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This article has now been amended by the BBC listing Long Covid as a cause.
add a skeleton here at some point
8 days ago
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When a virus that commonly causes cognitive dysfunction has been infecting and reinfecting the global population for years but is simultaneously being collectively ignored this is precisely the kind of normalisation you get.
www.bbc.co.uk/news/article...
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Brain fog and four easy ways to help fix it
It's common to become forgetful or mentally sluggish but there are easy ways to cut through the haze.
https://www.bbc.co.uk/news/articles/c87ydw7xdxvo
9 days ago
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Very impressed with the young guy - mid-thirties - I saw standing on the platform at the train station earlier today, with a slight cough but wearing a well-fitted blue surgical mask. It really is that easy to protect other people.
10 days ago
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In my experience, the general public often don't understand the extent to which critical infrastructure systems rely on very small groups of highly-trained individuals. In addition, some of these controllers will have lingering cognitive effects.
7news.com.au/news/covid-o...
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COVID outbreak blamed for Sydney Airport chaos
A COVID wave through Sydney Airport's control tower has left airlines furious and passengers stranded.
https://7news.com.au/news/covid-outbreak-in-control-tower-causes-sydney-airport-chaos-c-20000466
11 days ago
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This is precisely why Covid-19 vaccines should be available free of charge for everyone in the UK. The government not purchasing enough vaccines to make this possible is the definition of a false economy.
inews.co.uk/news/hospita...
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Hospital admissions for Covid hit 10-month high
Waning immunity and rising case numbers are the main drivers of the increase in hospital admissions, scientists say
https://inews.co.uk/news/hospital-admissions-covid-10-month-high-3913320
12 days ago
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The mindset that drives me to avoid Covid is exactly the same mindset that has kept me sober for over 18 years: recognition of the dangers of normalisation and complacency, a desire to optimise my health, and knowing that fleeting doubts are easily quashed by seeing consequences.
17 days ago
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What you are all witnessing now in the US - and, to a lesser extent, in other parts of the world - can be traced back to the tacit promotion of the erroneous idea that SARS-CoV-2 infection was somehow beneficial. Hybrid immunity is an immunological concept, not public health.
18 days ago
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Cases of H5N1 in which the source of infection cannot be traced always unnerve me. One of the children in California - infected in Dec of last year - is now in that category . These cases always raise the suspicion of an as-yet unknown mode of transmission.
www.cidrap.umn.edu/avian-influe...
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H5N1 detected in Texas dairy herd; researchers can't pinpoint source of California child's illness
https://www.cidrap.umn.edu/avian-influenza-bird-flu/h5n1-detected-texas-dairy-herd-researchers-cant-pinpoint-source-california
18 days ago
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1. While it is heartening that some individual state governors in the US are guaranteeing continued and unrestricted access to Covid-19 vaccines in their respective states, it is vital to remember that what is also urgently required is robust surveillance of H5N1.
19 days ago
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This illustrates exactly how the term, 'Covid' has come to mean, 'the non-pharmaceutical interventions adopted during the emergency phase of the pandemic', not the disease itself. The 'Covid effect' mentioned in the piece is actually acute C-19 and its sequelae.
www.irishtimes.com/ireland/educ...
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Opinion: Chronic absenteeism from school has worsened since Covid and must be tackled
Student attendance has deteriorated since Covid, with more than 30% of students in Deis second-level schools now defined as ‘chronic absentees’
https://www.irishtimes.com/ireland/education/2025/09/01/chronic-absenteeism-from-school-has-worsened-since-covid-and-must-be-tackled/
22 days ago
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'The unexpected finding that vaccination-only participants showed superior cross-neutralization compared to individuals with hybrid immunity challenges conventional assumptions about hybrid immunity advantages'.
www.medrxiv.org/content/10.1...
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Antibody responses to SARS-CoV-2 variants LP.8.1, LF.7.1, NB.1.8.1, XFG and BA.3.2 following KP.2 monovalent mRNA vaccination
The evolution of SARS-CoV-2 has resulted in antigenically distinct variants that challenge vaccine-induced immunity. The KP.2 monovalent mRNA vaccine was deployed in 2024 to address immune escape by e...
https://www.medrxiv.org/content/10.1101/2025.08.24.25333689v1
25 days ago
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This is an outstanding development.
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Australian-led trial shows nasal spray reduces COVID-19 risk in cancer patients - Peter MacCallum Cancer Centre
https://www.petermac.org/about-us/news-and-events/news/details/australian-led-trial-shows-nasal-spray-reduces-covid-19-risk-in-cancer-patients
25 days ago
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1. I was at my local pharmacy this morning to pick up a prescription, and as I walked up to the counter, I immediately noticed that the elderly woman in front of me in the queue was wearing a blue surgical mask. She was adjusting it, pulling it up over her nose.
27 days ago
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Biological risks are inseparable from politics.
27 days ago
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1. The single most pernicious and damaging societal imperative I see in action right now, with Ireland in a Covid wave, is this: 'There's no need to test'. Why? Not just because it tacitly normalises unmitigated transmission, but, more importantly, it hides Long Covid.
29 days ago
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1. Biological risk is both multifaceted and additive. Any of the following individual risks would be concerning; when combined, they effectively constitute a powder keg waiting for a spark:
about 1 month ago
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1. 'Overall, our findings raise compelling questions about the potential role of SARS-CoV-2 infection in accelerating or triggering neurodegenerative diseases linked to protein amyloidosis'. An example of such a disease is Parkinson's Disease (PD).
pubs.acs.org/doi/10.1021/...
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An Amyloidogenic Fragment of the Spike Protein from SARS-CoV-2 Virus Stimulates the Aggregation and Toxicity of Parkinson’s Disease Protein Alpha-Synuclein
Emerging evidence suggests that the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection may have long-term deleterious effects on the central nervous system and even contribute to p...
https://pubs.acs.org/doi/10.1021/acschemneuro.5c00478
about 1 month ago
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1. 'The findings of this study unveil a silent yet profound legacy of COVID-19: genomic instability as a potential driver of long-term health complications in survivors...
bmcinfectdis.biomedcentral.com/articles/10....
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The silent legacy of COVID-19: exploring genomic instability in long-term COVID-19 survivors - BMC Infectious Diseases
Background Persistent symptoms and complications reported by many patients for more than four weeks after contracting coronavirus disease 2019 (COVID-19) are referred to as post-COVID-19 syndrome. The...
https://bmcinfectdis.biomedcentral.com/articles/10.1186/s12879-025-11419-y
about 1 month ago
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1. 'SARS-CoV-2 is linked to “an unusually high level of ‘indiscriminate’ killing of T cells,” says Leitner, adding that this observation is “reminiscent of” measles, which can cause immune amnesia by depleting memory B cells...
www.bmj.com/content/390/...
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Why scientists are rethinking the immune effects of SARS-CoV-2
“Immunity debt,” a theory to explain the global surge in non-covid infections since pandemic restrictions were lifted, is increasingly being challenged by emerging evidence. Nick Tsergas reports Myco...
https://www.bmj.com/content/390/bmj.r1733
about 1 month ago
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With the caveat that the study this article is referencing is a preprint, a 35% risk increase for Long Covid following reinfection is both significant and concerning. The study also provides more evidence that vaccination reduces risk; it's worth reading in full.
add a skeleton here at some point
about 1 month ago
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Remember: if anyone says, 'we need to live with Covid' but doesn't also talk about vaccines, therapeutics, and mitigations, they're not actually saying we need to live with it, they're saying, 'I want to ignore it'.
about 1 month ago
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Very obvious now that SARS-CoV-2 infection can be characterised as: AAA A: Acceleration (e.g. dementia, vascular) A: reActivation (e.g. EBV, LTBI) A: Aging (inflammation, telomere shortening) Longevity and / or healthspan cannot be fully addressed without understanding this.
add a skeleton here at some point
about 1 month ago
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1. As a consultant analyst that generally presents to the C-suite of organisations, I am often asked to produce short, concise explanations of both biological and geopolitical risks. Regarding Covid-19, I use the same summary with both C-level clients and friends:
about 1 month ago
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The clear benefit of Covid-19 vaccination demonstrated in this study illustrates exactly why limiting access to vaccination is a significant negative to productivity and the economy in general.
www.news-medical.net/news/2025081...
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Long COVID linked to lasting financial hardship and work disruption
While the economic impact of the COVID-19 pandemic continues to be widely studied and debated, the financial toll of the COVID-19 pandemic for individual patients is less understood.
https://www.news-medical.net/news/20250812/Long-COVID-linked-to-lasting-financial-hardship-and-work-disruption.aspx
about 1 month ago
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Antimicrobial resistance (AMR) is arguably the most urgent biological risk facing the world. The development of new antimicrobials that can combat resistant pathogens is critical for global health security. A pandemic could be caused by an antimicrobial resistant pathogen
www.bbc.com/news/article...
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Superbugs: Antibiotic-resistant infection left me with hip of a 70-year-old
Amy Symington, 21, had to learn to walk again an abscess in her hip became septic and did not respond to antibiotic treatment.
https://www.bbc.com/news/articles/c4gmmrvlxnjo
about 1 month ago
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Sunset earlier this evening from Ramore Head, Portrush, Northern Ireland.
about 1 month ago
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1. I've said exactly this for quite some time. Expanding on Adrian's
@sillyputty78.bsky.social
point on X / Twitter here, Covid-19 has three distinct characteristics as a disease that enables it to be denied at a societal level.
about 1 month ago
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'Another consideration, when it comes to building immunity, is the growing body of research suggesting that for several months after a Covid infection, people become more vulnerable to other infections...'
www.theguardian.com/world/2025/a...
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What do we know about the Covid-19 virus five years on?
As the virus continues to evolve, experts assess its latest variants, seasonal prevalence and levels of vaccine uptake
https://www.theguardian.com/world/2025/aug/07/what-do-we-know-about-the-covid-19-virus-five-years-on
about 2 months ago
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reposted by
Conor Browne
Kristie De Garis
about 2 months ago
No longer just a thought, a proposal, seven messy drafts, a pre-order... DRYSTONE - A LIFE REBUILT is officially launched!
#Scotland
#Books
#Writing
#WritingCommunity
#Book
#Nature
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1. The future development of Covid-19 vaccines that are much more resilient in the face of SARS-CoV-2 mutation is very important, but, as I noted in my own report earlier this year:
about 2 months ago
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1. A recent conversation with a colleague threw into sharp relief exactly why I am so inspired to develop technologies to prevent pathogenic infection. So, if you'll indulge me, let me explain. In early 2002, I had what to all intents and purposes was a cold. Sniffles, cough etc.
about 2 months ago
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'Immune dysregulation following Covid may compromise the body's ability to mount an effective defence against common respiratory pathogens'.
timesofindia.indiatimes.com/city/kolkata...
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City doctors blame ‘long Covid’ for severe viral infections that have laid Kolkata low | Kolkata News - Times of India
Kolkata: The pandemic may have ended three years ago but it continues to cast its shadow on the city's healthscape.A past history of ‘long or severe' .
https://timesofindia.indiatimes.com/city/kolkata/city-doctors-blame-long-covid-for-severe-viral-infections-that-have-laid-kolkata-low/articleshow/123051604.cms
about 2 months ago
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1. I have to declare this an
#ad
because I’ve consulted for the company concerned, but this is another huge step forward for Covid-19 screening by
@raisonance.bsky.social
This is the first commercially available fully online clinical decision support screening solution for Covid-19...
add a skeleton here at some point
about 2 months ago
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Looking down the Mourne Wall, from the summit of Slieve Donard, in the Mourne Mountains of Northern Ireland.
about 2 months ago
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Always reactivation. Evidence for: Reactivation of Epstein-Barr Virus (EBV) Reactivation of latent Tuberculosis (LTBI) Reactivation of dormant cancer cells. The downstream negative population health effects of unmitigated SARS-CoV-2 transmission are undeniable now.
add a skeleton here at some point
about 2 months ago
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1. 'They observed that genes associated with neuronal metabolism and activity are deregulated in these animals' brains in a way that is reminiscent of the molecular signatures...
www.pasteur.fr/en/home/pres...
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Long COVID: SARS-CoV-2 persists in the brainstem in the long term and deregulates neuronal activity
Symptoms can persist in some SARS-CoV-2 patients several months after infection. Scientists at the Institut Pasteur have demonstrated in an animal model that SARS-CoV-2 infects the brain and persists ...
https://www.pasteur.fr/en/home/press-area/press-documents/long-covid-sars-cov-2-persists-brainstem-long-term-and-deregulates-neuronal-activity
about 2 months ago
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1. The most important concept in this excellent article is this: 'the team wanted to explore what he called a “*reciprocal relationship*” between COVID-19 and chronic conditions'. * my emphasis
www.oregonlive.com/health/2025/...
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OHSU study suggests long COVID may be more common than previously thought
Even mild cases of COVID-19 in monkeys were linked to chronic health conditions that emerged later.
https://www.oregonlive.com/health/2025/07/ohsu-study-suggests-long-covid-may-be-more-common-than-previously-thought.html
about 2 months ago
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Looking down Glenariff Glen while hiking on the Garron Plateau earlier today.
about 2 months ago
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1. The idea that previous infection with seasonal flu may provide some protection against severe disease in subsequent H5N1 infection (thus potentially explaining why the majority of human cases of H5N1 in the US thus far have been mild) is positive news.
www.cidrap.umn.edu/avian-influe...
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Ferret study suggests seasonal flu immunity may protect against severe H5N1 infection
https://www.cidrap.umn.edu/avian-influenza-bird-flu/ferret-study-suggests-seasonal-flu-immunity-may-protect-against-severe
about 2 months ago
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1. The problem with the 'you must have had an asymptomatic infection' assertion is the premise which underpins it, namely that *infection is inevitable*. Infection is not inevitable.
2 months ago
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This is absolutely wonderful to see - my dear friend Kristie's debut book in the wild. Kristie takes Covid as seriously as I do, and her writing is absolutely fantastic. Thoroughly recommend you pick up a copy.
add a skeleton here at some point
2 months ago
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1. I had a gastroscopy at a clinic in Belfast a couple of weeks ago. During the admissions procedure, I was in a small ward having a discussion with my doctor and the admitting nurse. When the nurse asked if I'd ever had Covid, and I answered no, my doctor said, 'no way'.
2 months ago
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1. I've said this several times before on this platform, but the exact moment I knew that I was going to do everything I could to avoid infection with SARS-CoV-2 was when I read an email in February 2020 confirming that anosmia was a cardinal symptom of Covid-19.
2 months ago
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Extremely important article on reassortment, H5N1, and pandemic potential. As I've said before, if the situation in the US regarding bird flu had happened in 2019, it would be treated like the grave emergency it is.
www.scientificamerican.com/article/how-...
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Gene-Swaps Could Let Influenza Jump Species
Influenza viruses like bird flu can mix and match their genomes, and this has played a role in at least three of the last four flu pandemics
https://www.scientificamerican.com/article/how-influenza-reassortment-may-make-bird-flu-more-dangerous/
2 months ago
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1. The most important point in this article is the 20% study group prevalence of anosognosia: having cognitive dysfunction but not being aware of it.
academic.oup.com/acn/advance-...
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Profiles of Individuals With Long COVID Reporting Persistent Cognitive Complaints
AbstractObjective. A subset of COVID-19 patients continues to experience cognitive difficulties 24 months post-infection. The factors driving these symptom
https://academic.oup.com/acn/advance-article/doi/10.1093/arclin/acaf064/8196889
2 months ago
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Although risk management, when it involves the safety of human beings, always, by definition, has an ethical component, I firmly believe that it is always detrimental when the management of risk (or lack thereof) shifts from pragmatism into the realms of ideology or identity.
2 months ago
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