The Memphis Belle, flying out of RAF Bassingbourn in Cambridgeshire, became the first US bomber to complete 25 missions over Nazi Europe. Her story lives on in Norwich’s Heritage Week exhibition. eastangliabylines.co.uk/lifestyle/hi...

What on earth is going on.

🧬 VDJbase and OGRDB: 3000+ IG/TR samples across human and rhesus macaque with curated AIRR-seq and long-read genomic data. LET'S CHANGE THE WAY WE UTILIZE IG/TR GENOMIC AND REPERTOIRE DATA! @guryaari.bsky.social @williamlees.bsky.social @ayeletperes.bsky.social academic.oup.com/nar/advance-...

New manuscript out in NAR! tinyurl.com/4rrbuesn 🧬 VDJbase and OGRDB now support 3000+ IG/TR samples across human and rhesus macaque with curated AIRR-seq and long-read genomic data. From population analysis to precision annotation. @guryaari.bsky.social @cdubsig.bsky.social @williamlees.bsky.social

Vital piece of investigative reporting from Sky. They've uncovered the X algorithm which feeds users extremist right wing material from the moment they join the site. It is a far-right radicalisation engine, by design. news.sky.com/story/the-x-...

On Oct 1, 2025, GISAID informed us that they had ended updates to the flat file of SARS-CoV-2 genomic sequences and associated metadata that we had used to update Nextstrain analyses since Feb 2020. GISAID's stated rationale was that their "resources are limited". 1/5

Imagine trusting your national space programme in to the hands of someone who is constantly advocating for civil war and and end of democracy in your country.

Yesterday Nigel Farage argued that the UK has failed to grasp Brexit opportunities to deregulate, which his 'pro-business' government would deliver. I've got a piece in the Independent arguing why that is a misreading both of Brexit history and economics. www.independent.co.uk/voices/brexi...

So a weird thing happened to me in Aldi that I cdn't quite place until I was listening to Gabby Bertin talking about choking in porn on the radio this am. (NB: this is 100% not a sex thing). Having the usual polite chitchat with the cashier who is tired from working extra shifts to make £ for xmas..

X is a cesspit led by an unhinged billionaire who is desperately trying to stir up civil war in Britain. Nobody with any sense or decency should be there. No organisations, government departments, or politicians should be there. Everyone who is, is enabling this monster.

Happy to announce the publication of our work exploring under-appreciated genetic diversity in the human IGHC region. Awesome work by @uddalok.bsky.social. So grateful for our amazing co-authors. @williamlees.bsky.social @guryaari.bsky.social @ayeletperes.bsky.social www.cell.com/cell-genomic...

For over 20 years, the mouse model organism has helped scientists uncover the biology behind human health and disease. But the mouse reference genomes still have missing pieces. The first collection of telomere-to-telomere mouse genomes are now available for two key mouse strains. 🧬💻

📢 We are announcing the Adaptive Immune Profiling Challenge 2025! Can you predict immune state labels from adaptive immune receptor repertoires? 💰 $10,000 prize pool! 🗓️ Launches Nov 5 on @kaggle.com More Info: uio-bmi.github.io/adaptive_imm...

Boris Johnson says at the inquiry "it was slow to dawn on government generally about the full horror of of Covid." Why? Why was it so slow to dawn on the government what could happen? That slowness cost lives and livelihoods at a grand scale.

Serious questions for the Wellcome Trust and Wellcome Leap to answer here. Allocating $50m to microbiome pseudoscience is bad enough. But things get alarmingly murky when you notice that the Program Director is working on commercial microbiomics products.

#A_NewHope ✊

Anti-BCMA CAR-T therapy in patients with progressive multiple sclerosis: Cell www.cell.com/cell/fulltex...

So proud to be working for a company that's helping build a better Internet arstechnica.com/ai/2025/10/i...

The simple fact is that the Government is going to have to find a way of rebuilding local government finances systematically. The decay of public realm and social infrastructure is deeply corrosive of public trust. Everyday, people can see the state not working all around them.

This deserves more attention than it has received. Gove: "we were too anxious as a government to secure those deals in order to show that Brexit was working". Exactly as so many of us warned at the time, and as the government denied at the time. www.yorkshirepost.co.uk/country-and-...

Our latest research shows: Tory voters are now more than twice as likely to consider Brexit a failure for the UK (46%) compared to a success (22%). https://leftfootforward.org/2025/10/even-tory-voters-say-brexit-has-failed-and-damaged-uk-economy-poll-finds/

A high-resolution, unbiased analysis of the cellular immune response to Epstein-Barr virus https://www.biorxiv.org/content/10.1101/2025.10.09.681317v1

I #AGREE "Functional characterization and transcriptomic mapping of T cells remain #incomplete without knowledge of their #clonal #antigenic #specificities. www.biorxiv.org/content/10.1...

This article manages to name her husband before it names… her.

Why the mathematics used in economics for decades needs a rethink, according to Tim Harford: on.ft.com/3KrvyP8

“I don’t see why a man should take thirty pages to describe how he turns over in his bed before he goes to sleep.” A publisher rejecting Proust. Every academic - “Can you really do that properly in a mere 30 pages?”

Turns out...just like in the antibody heavy chain repertoire, germline variants in the immunoglobulin lambda and kappa loci influence the composition of light chain B cell receptors! Way to go Eric @e-engelbrecht1.bsky.social !!!! www.biorxiv.org/content/10.1...

New preprint from our group in collaboration with the awesome Prof. Ranjan Sen (NIH). We show that IGH polymorphisms establish inter-individual differences in the pro-B antibody repertoire that persist into the naive B cell pool. Oscar L. Rodriguez is killing it! www.biorxiv.org/content/10.1...

New BCR reconstruction tool for scRNA-seq: assembles full heavy & light chains and annotates constant regions. Check it out: www.biorxiv.org/content/10.1... #scRNAseq #immunology

I really appreciate how Dr. Glaucomflecken has become all of medicine and public health's emotional support ophthalmologist. I sat through 16 hours of ACIP meetings last week. If I do not laugh, I will cry.

A majority of Labour party members - who are on any metric rather more socially liberal than the average voter - back ID cards. Plenty of polling showing they are popular with voters in general. Perhaps the zombie myth that British voters oppose them will die at last? labourlist.org/2025/09/digi...

I think the key problem here is a continuing assumption, in traditional media, that when the White House speaks on a major topic, this is a big news story. That model can't cope with a president with no regard for truth, who's in constant broadcast mode, & who veers around from one day to another.

Brilliant. Now every mother of an autistic child is going to say “I took paracetamol!” And every mother of a “neurotypical” or not yet diagnosed child - “I took paracetamol but I was lucky!” And we can all forget about awkward uncles or misfits from our youth, because there was no name for it then.

I like this. Since under RFK Jr, Covid shots are now for people with underlying conditions that put them at risk, Michigan’s chief medical executive Dr. Natasha Bagdasarian states that not having the most recent Covid shot constitutes such an underlying condition. www.michigan.gov/mdhhs/inside...

Q: What was RFK Jr's reaction when you raised the need to consult scientific evidence? Former CDC Director: He stated there was no scientific evidence associated with vaccines. He called CDC the most corrupt agency in the world. He said that CDC employees were horrible people, were killing children

About bloody time too

Sure, Conservatives are right to ask why Starmer tolerated a paedophile’s friend as US ambassador but why are they not concerned about the PM hosting another pal of Epstein, one who has repeatedly lied about their relationship? And why are BBC interviewers not asking them about this?

"To our untrained eye, a corn field looks more 'natural' than an array of solar panels. But a corn field is a biological desert ... Put up some solar panels, and add some plants that only need to be mowed once a year or so (sometimes with sheep) and you see an explosion of life."

🇺🇦🚀 Zelensky: "The most effective sanctions are fires at Russian oil refineries, terminals and oil depots."

Yes thousands turned out - which is far more than I’d like - but that is dwarfed by the millions that understand real patriotism means loving your country as it actually is, not hating its diversity or trying to exploit its challenges. That’s what our flags actually represent

I do admire how relentlessly you keep up your campaign. It must be very draining to confront these horrible people every day.

The people marching in London today are very obviously the ideological descendants of the Mosleyite BUF fascists of the 1930s. The mainstream news and media are too timid to point it out, but that's what they are - and we normalise it at our peril.

Still the best explanation of Russian tactics and the difficulty of deterrence. From: Yes, Prime Minister.

Notre ville change ! Nos rues sont peu à peu rendues aux habitants, de nouveaux arbres sont plantés et les promenades facilitées et sécurisées. C'est le cas de la rue Chaptal dans le 9e ou celle du Docteur-Lecène dans le 13e !

🔴BBC Accused of Pro-Reform Bias as Lib Dems Launch Campaign to End ‘Wall to Wall’ Farage Coverage They accuse the BBC of “following Farage around like a lost puppy” and have complained to Ofcom to demand fair coverage bylinetimes.com/2025/09/09/b...

This is infuriating. What is the point of a Marine Protected Area if trawlers are allowed to keep ploughing it? Yet again, the government has succumbed to commercial lobbying. www.theguardian.com/environment/...

Labour should be aggressively attacking this kind of dangerous anti-science conspiracism

Who is Dr Angus Dalgleish, the "eminent oncologist" cited by a speaker at Reform conference for the claim that Covid vaccines caused cancers in the royal family? Well, buckle up, because he isn't your average quack doctor! www.bbc.co.uk/news/article...

Just find it a bit bleak that John has put without caveat “fewer people coming from abroad to work or study in the UK” as a reason to not feel gloomy.

Echoes of Enrique Peñalosa's “A developed country is not a place where the poor have cars. It’s where the rich use public transportation."