Excellent paper. I really hope #LongCovid researchers implement these recommendations.

Out today - our recommendations for Long COVID clinical trial design, focusing on currently available outcome measures: www.sciencedirect.com/science/arti... We make 5 overarching recommendations for Long COVID clinical trials: 1) thorough characterisation of baseline disease 1/3

Holiday gathering reminder 🎁 If your guests test w/rapids twice before the event, 48 hours apart, it’ll catch 63% of Covid cases even if they have no symptoms. Testing 3x improves that to 79%! This is how we curb the annual January surge that gave me Long Covid—thanks for protecting yr community 🤍

At 27 responses! I am aiming for at least 50, 100 would be great. Here's a sneak peek of some of the ratings. I also spoke with a few doctors running LC & ME trials to get their take on legislative priorities! Please keep sharing :)

Great piece by Eric Topol!! A must read.

Important new, large (N>28,000 women) randomized clinical trial of breast cancer screening: age-based vs risk-based by polygenic risk score, genomics "opportunity to modernize screening" jamanetwork.com/journals/jam...

If you have ME/CFS (even without a formal diagnosis) & live in California, I would love if you could fill out & share this survey with your friends. I am trying to prepare for a few legislative meetings I have in January w/ some old colleagues. Responses are anonymous! cryptpad.fr/form/#/2/for...

Thanks to the Long COVID community, eligibility screening for LoCITT-T is now closed, 41 days after it oopened. We'll share more about what's ahead on 12/17 at 2:30 eastern / 11:30 pacific. scrippsresearch.zoom.us/webinar/regi... For those who have taken the screener but not consented yet... 1/2

I'm consistently impressed by the crucial content @thesicktimes.org publishes (yes, their end of year fundraiser is still going on if you want to support and/or share the-sick-times.fundjournalism.org/donate/)

There are a lot of horrifying things happening in the world, but it is a special kind of infuriating that someone in an official government role would waste time on this "petty" (as Rachel Levine called it) act when they should be addressing the numerous legitimate challenges our nation is facing.

We're hosting a LoCITT-T update webinar on 12/17 at 2:30 eastern / 11:30 pacific. We've received a lot of questions about what the experience might be like for those who believe they're receiving the placebo. We'll answer those & more. Register here: scrippsresearch.zoom.us/webinar/regi... 1/2

Fewer than 50 slots left in this Long Covid trial (down from 1000!) They’re especially hoping to enroll folks from North Dakota, Mississippi and Puerto Rico, as well as more BIPOC participants. To sign up: longcovid.scripps.edu/locitt-t/?ut...

Note also there are quite a lot of people who started but not yet finished enrollment, so if that’s you and you do want to participate, now’s the time!

“You are wasting taxpayer dollars by not having a scientific discussion... The best thing you can do is adjourn the meeting and discuss vaccine issues that actually need to be taken up. ... Your job as a committee is to look at the totality of the risks and benefits, the harms, the equity…"

Now >900 LoCITT-T participants. We're close to a last call for participants! Still hoping to enroll folks from ND, MS, & PR & more BIPOC participants: longcovid.scripps.edu/locitt-t/?ut...

A new review of post-infection syndromes, including #LongCovid, and its diverse immunologic manifestations www.cell.com/trends/immun... by @virusesimmunity.bsky.social and colleagues

If I had all the resources of the federal government and a particular interest in long-term follow-up studies of vaccine trials, I would simply DO long-term follow-up studies of all the vaccine trials we’ve already done.

This was surprisingly fun! Love that they included what proportion of your images have alt text (100% here!)

We're thrilled to announce that thanks to two generous donors, the Silver Giving Foundation and Lunardelli-McRee family, all donations made to PLRC will be matched up to $100K through January 1 of next year! Support our work: patientresearchcovid19.com/donate/

Speaking of clinical trials, we were thrilled to help announce a new all-remote trial -- led by @julialmv.bsky.social, who is also one of our advisors. (5/10) thesicktimes.org/2025/10/30/w...

It’s #GivingTuesday! Will you help us get our fundraiser back on track and keep our #LongCOVID journalism going? the-sick-times.fundjournalism.org/donate/

Now >900 LoCITT-T participants. We're close to a last call for participants! Still hoping to enroll folks from ND, MS, & PR & more BIPOC participants: longcovid.scripps.edu/locitt-t/?ut...

Required reading if you care about someone with Long COVID: thesicktimes.org/2025/11/28/y... "It’s exhausting, having to constantly censor this part of myself... Avoiding the topic feels absurd — like I’m standing in quicksand, & we’re chitchatting over glasses of lemonade as I slowly sink."

If you have relatives with long covid and will be seeing them tomorrow (or won’t be because they have long covid) please spread the word about this trial of tirzepatide for LC. I’m enrolled, the anecdotes I hear from patients on it for other reasons are very encouraging.

There are >800 LoCITT-T participants, & >200 people who are eligible & just need to take one more step to claim their spot. There's time for new folks to join! We're particularly hoping to enroll folks from ND, MS, & PR & more BIPOC participants: longcovid.scripps.edu/locitt-t/?ut...

baby just posted his second ever tiktok! trying to spread the word about the @julialmv.bsky.social's amazing clinical trial. www.tiktok.com/t/ZTr2Rnwry/ if you are a tiktok user could you like and engage so it gets picked up? let's get this trial fully enrolled in record time!

We've enrolled more than 700 participants (of 1,000 planned) in 3 weeks to a randomized trial for treatment of #LongCovid

We are up to 688 LoCITT participants! If we could enroll all 1,000 participants within a month of launch (by 11/30), it would send a powerful message about the demand for remote Long COVID clinical trials. We appreciate the community's help to spread the word: longcovid.scripps.edu/locitt-t/?ut...

A few charts we created for this analysis.

Not knowing about PEM is proof positive you don't know IACCs. Even if you're not studying #MECFS, omitting the possibility of PEM in a trial for #LongCOVID (where many meet criteria for #MECFS) or for common comorbidities, like fibro, hypermobility disorders like #EDS, or #POTS is in error.

I've been surprised to see how many Long COVID trials focus on exercise & how few measure PEM. Thanks to @spichaksimon.bsky.social for covering this in @thesicktimes.org "Testing exercise is “money down the drain” & won’t advance understanding of LC, experts say" thesicktimes.org/2025/11/21/l...

Wanna see a visual on the result of the Republican attack on public health? I’ve got you covered. This is from Pew Research Center’s most recent survey, showing a 27% drop in Republican support for school vaccine requirements from 2016-2025.

We are witnessing a poisonous effort to destroy what the vast majority of Americans know is a key pillar of public health. Vaccines are responsible for 40% of the reduction in child mortality achieved in the last half century.

If you're over legacy media, I've got great news! You can donate to our non-profit newsroom at @thesicktimes.org to help us keep investigating injustices, challenging powerful institutions, and offering a platform for those affected by the #LongCOVID crisis. the-sick-times.fundjournalism.org/donate/

Great to see this meta-analysis in BMJ: "Decentralised trials provide similar answers to clinical questions as traditional, non-decentralised randomised trials. They do not systematically overestimate or underestimate effect estimates, ..." www.bmj.com/content/391/... 1/2

In decades to come, we will look back at 2025 - following the most devastating pandemic in a century - as the year we turned back hard-earned progress on combating infectious diseases. That means the comeback of preventable diseases. And the emergence of new ones. www.science.org/content/arti...

The new approach is essentially to stick your head in the sand and go to the gym as a model for pandemic preparedness. Suffice to say, such a model will not work, but I don't want to belabor the point - I have made it many times already. E.g., here: bsky.app/profile/kgan...

Congrats Eric - what a well-deserved honor! “I never lose my optimism about advances in bio medicine and in the practice of medicine,” he says. Even if there are efforts to suppress that work, if it’s important enough, scientists will pursue it. “We just have to figure out a path to get it done.”

If you're not devastated by this news, please read some of Alice's work. She was a champion for justice, lifting the voices of a broad array of disabled people, and disabled joy ❤️ disabilityvisibilityproject.com/book/

It is such a joy to share this trial with the Long COVID community! We know the second 500 will be tougher to recruit & we'd love your help to finish enrollment quickly with as much diversity as possible longcovid.scripps.edu/locitt-t/?ut...

The Scripps tirzepatide trial is in @wired.com today! Thanks so much for covering this @emilymullin.bsky.social! The signup link for the trial: longcovid.scripps.edu/locitt-t/?ut...

GLP-1s are being studied for a wide range of conditions. Now, scientists will test whether their anti-inflammatory properties can help alleviate symptoms of #LongCovid. @wired.com @emilymullin.bsky.social www.wired.com/story/weight...

LoCITT-T trial was covered by Wired today: www.wired.com/story/weight... My comments include: "For the long Covid population...if you’re requiring people to come into a clinic, you’re systematically excluding the most severely affected folks who are housebound or bedbound."

I just had the thought "we're half way there" And now I will have Bon Jovi in my head for the foreseeable future Send prayers (yes that's a joke)

Please spread the word about this exciting #LongCovid trial that they’ve made super easy to participate in from home! The faster they get enough participants, the faster they can release results

This was a fun one - we talked through each step of my career from grad school to LoCITT-T, as well as my hope for the future of accessibility & inclusion in clinical trials & health research.

Our randomized, placebo-controlled trial of tirzepatide (Zepbound) for #LongCovid has already enrolled 500 participants of 1000 planned in less than 2 weeks! longcovid.scripps.edu/locitt-t/

There are LoCITT-T participants across 46 states & DC! We currently do not have participants from: North Dakota South Dakota Mississippi Puerto Rico Can you spread the word to anyone with LC there (or in any other, more generally underrepresented community): longcovid.scripps.edu/locitt-t/?ut...

Many Long COVID trials have reported negative results in 2024 and 2025. In our Comment for @thelancetinfdis.bsky.social we argue that inadequate outcome measures might have played a role. (1/12)

I really do think The Sick Times is doing some of the most important journalism of our generation. And I can tell you firsthand that Miles and Betsy are the real deal. They care so, so much about getting it right. They’re incredible humans in addition to being such good journalists.