Before #MECFS, Nicky was always on the move — raising her children, volunteering, and giving back. She and her husband even opened their home to more than 20 foster children, creating a safe and loving space for each one. Read Nicky's story👉 ow.ly/szlG50XoneM.

🌍 People worldwide used their limited energy to finish “ME/CFS is…” Their voices show the challenges, losses & urgent need for change. Thanks to matching donors, every gift to OMF is tripled up to $500K! 👉 Donate: www.omf.ngo?form=donate-.... #mecfs #pwME #mecfsresearch

In #MECFS, there’s evidence that microglia are activated more often than in healthy people, which contributes to #neuroinflammation. OMF’s CRC at Uppsala is analyzing microglia activity via MRI as a way of detecting neuroinflammation. 👉 Learn more: www.omf.ngo/microglia/

📊OMF's Computational Research Center & patient-researcher Martha Eckey analyzed 150+ treatments reported by 3,900+ people with #MECFS & #LongCOVID through the TREATME survey. Hear Dr. Xiao & Dr. Meadows discuss what these findings mean: ow.ly/PVvn50XmvW4.

🌟 Kick off a TRIPLE MATCH Fundraiser for OMF! 🌟 Follow this link to launch in as little as 60 seconds: www.omf.ngo/digital-fundraising-toolkit/. ALL donations to your fundraiser will be tripled between November 1 -December 2, 2025! #MECFS #LongCOVID #pwME #pwLC

🌟Triple Giving November is back! From November 1 to December 2, all gifts to OMF will be tripled, up to $500,000, thanks to generous matching donors. 👉 Triple your gift today and learn about other ways to support OMF: ow.ly/6RrM50XlkLk. #pwME #MECFS #pwLC #LongCOVID

💙 Triple Giving November (TGN) is returning! From Nov 1–Dec 2, every dollar you give to OMF will be TRIPLED (up to $500,000) to advance #MECFS & #LongCOVID research. Learn what to expect during TGN here: ow.ly/oJb550XkvOB.

Oxygen uptake efficiency slope (OUES) is an indicator of cardiorespiratory health. In #MECFS, OUES has been found to be decreased, which means that some people with ME/CFS consume oxygen less efficiently. 👉 Learn more: www.omf.ngo/oxygen-uptak...

Whitney Dafoe: My life is a math equation. I live every moment by this: X energy use = Y outcome. I evaluate every single tiny thing I do based on this equation, often with long, in depth analysis. Imagine being healthy, not having this equation, and just acting on every impulse without thought.

2nd International Conference on Clinical and Scientific Advances in ME/CFS and Long COVID 📍 Porto, Portugal or online OMF speakers will include: Linda Tannenbaum, OMF Founder & CEO, David Systrom, MD, Johanna Squires. 👉 Explore the program: ow.ly/hWwK50XivaM.

On Tuesday, OMF brought together Directors from all our Collaborative Research Centers for a monthly meeting to exchange insights and advance research on #MECFS and #LongCOVID. Pictured: CRC Directors, Linda Tannenbaum, Danielle Meadows, and Maureen Hanson.

🎥 Recordings Available: Community Symposium on the Molecular Basis of ME/CFS 👉 Access them here: ow.ly/Aw2G50XcIIO #MECFS #pwME

🧬Science Wednesdays A signaling pathway is a series of events on and within a cell that conveys information and leads to a specific function or response. Learn more about signaling pathways and a study investigating the tetrahydrobiopterin (BH4) pathway: ow.ly/2i6A50XbPsq #pwME #pwLC #BH4

From the OMF-Supported Medical Education Resource Center (MERC) at Bateman Horne Center: Orthostatic intolerance & #POTS are common in #MECFS & #LongCOVID. Learn signs + management tips: ow.ly/iz3b50Xb2QJ #POTSAwarenessMonth #UnitedForME @batemanhornecenter.bsky.social

OMF’s Collaborative Center at Montreal, in collaboration with our Melbourne ME/CFS Collaboration, has released a new paper: Circulating Levels of SMPDL3B Define Metabolic Endophenotypes and Subclinical Kidney Alterations in Myalgic Encephalomyelitis. 🔗 ow.ly/uY8x50WW32a #mecfs #pwME

October 9 is DAF Day—a national day dedicated to the power of Donor-Advised Funds (DAFs) to make a difference. This year, you can multiply your impact by directing a grant from your DAF to OMF. To learn more about DAFs, visit our ways to donate page: www.omf.ngo/ways-to-dona....

🧬Science Wednesdays: Metabolism There are a couple important ways metabolism is studied in ME/CFS. For one, the #mitochondria play a central role in metabolism and there’s a growing body of evidence showing mitochondrial dysfunction in #MECFS. (1/3)

Give your car new purpose this Cartober! When you donate your car, truck, motorcycle, RV, or boat to OMF, the proceeds from your sale will support #MECFS and #LongCOVID research. To learn more, visit: ow.ly/4zvh50X74vv.

🔬Help advance #MECFS and #LongCOVID research by joining OMF’s StudyME, a free participant registry that connects you with researchers conducting studies in these areas. Healthy volunteers needed too! 👉 www.omf.ngo/studyme/ Already part of StudyME? Please share this post to reach more people.

In clinical trials, there are different treatment groups that a participant gets put into when they start the trial. Blinding is when different people involved in the trial are kept unaware, or blind, to which group the participant is in. Learn more: www.omf.ngo/what-is-blin....

#MEAction is asking you to take action to save telehealth NOW! You can call or email your member of Congress. To make this action easier, we have drafted up a sample script you can use: www.meactions.org/telehealth #Telehealth #PwME #LongCovid #MECFS #Congress #Disability

🛍️ Shop with iGive! With iGive you can shop online at 1,700+ stores, and a percentage of your purchase will go directly to OMF, all at no cost to you or OMF. Shop & Support OMF 👉 ow.ly/23iX50X3AV7. #ShopWithPurpose #pwME #pwLC

Autoimmunity is the presence of antibodies and T lymphocytes that react to normal parts of a person’s system. OMF’s ME/CFS CRC at Uppsala has found an upregulation of autoantibodies in up to 70% of people with #MECFS in a preliminary study. Read more: www.omf.ngo/autoimmunity/

Today is my birthday, and I’m turning 34. Do I feel my age? No. The perception of age vanished at some point while I became chronically ill. Still, there are fleeting moments when I’m reminded of it. 1/9 #MECFS #pwME #Photography @openmedf.bsky.social

Linda Tannenbaum (OMF Founder & CEO), Kimberly Hicks (CFO/COO/Treasurer), and Danielle Meadows (VP of Research Programs) are visiting Boston for in-person meetings. Here are a few photos from yesterday’s meeting with researchers from OMF’s Harvard ME/CFS Collaboration. .

OMF Collaboration Investigates Molecular Basis of Post-Exertional Malaise (PEM) 👉 Read more from Dr. Moreau: www.omf.ngo/haptoglobin-.... Key findings: ➡️ After a mild stress challenge, #pwME showed a sharp drop in haptoglobin (Hp) levels, while healthy controls did not. (1/2)

🍂 Did you know you can support OMF research by donating any unwanted vehicles? Cars, trucks, boats, and even farm equipment can help us accelerate our work to end #MECFS and #LongCOVID. Donating is easy, and the pick-up is free. 👉 Get started today: ow.ly/rzTa50UXR3I.

"Metformin is an intriguing multiaction drug that may play a significant role in treating ME/CFS & LC. Although more research is needed to refine dosing and delivery methods, the accumulating evidence suggests it could soon be integrated into clinical practice." #MEcfs #LongCovid

OMF’s Collaborative Center at Montreal, in collaboration with our Melbourne ME/CFS Collaboration, has released a new paper: Circulating Levels of SMPDL3B Define Metabolic Endophenotypes and Subclinical Kidney Alterations in Myalgic Encephalomyelitis. 🔗 ow.ly/uY8x50WW32a

A new review from Melbourne ME/CFS Collaboration, in collaboration with Collaborative Center at Montreal, highlights the potential of metformin, an antidiabetic agent, as a treatment for #MECFS and #LongCOVID. 👉 Read the full publication: ow.ly/uXQJ50WVZax

🧬 Science Wednesdays: What is Proteomics? Proteomics is the study of the set of proteins present in the body at a given time. Looking at protein levels is a critical part of OMF’s large-scale biomarker study, BioQuest. Learn more about proteomics and BioQuest here: www.omf.ngo/what-is-prot....

List of orgs: #MEAction, Solve ME, Open Medicine Foundation, Bateman Horne Center, Renegade Research, Massachusetts ME/CFS & FM Association, Simmaron Research Inc., Complex Disorders Alliance (CODA), and CORe Community, Inc. (COVID Recovery through Community) all

RECOVER TLC clinical trials should include subgroup tracking and analysis for ME/CFS (using IOM criteria), POTS & other forms of dysautonomia, and MCAS. We joined several orgs in signing a letter sent to RECOVER TLC leadership. Letter: ow.ly/nFUa50WU60F #LongCovid #pwME #NIH

In April 2023, we launched OMF StudyME, a free global registry connecting people with #MECFS, #LongCOVID & related diseases to researchers. 🙌 Over 14,000 participants have joined! Sign up in <5 mins & help accelerate research 👉 www.omf.ngo/studyme

Wenzhong Xiao discussing the treatments survey that I have literally already cited twice 😂 Hey, it's great work! 🧪 The paper is here: pubmed.ncbi.nlm.nih.gov/40627388/

New Papers: OMF CRCs at Stanford and Montreal 🌟Microfluidic Assessment of PO2-Regulated RBC Capillary Velocity in #MECFS 🌟Circulating FGF-21 as a Disease-Modifying Factor Associated with Distinct Symptoms and Cognitive Profiles in #ME and #Fibromyalgia ow.ly/6KO350WRwVz

You are invited to join #MEAction for our latest Pillow Writers’ Salon on Thursday, September 18th at 11am PT/2pm ET/7pm UK. Register: us06web.zoom.us/meeting/regi... More about Pillow Writers: pillowwriters.wordpress.com #pwME #MECFS #spoonie #WritingCommunity #LongCovid #MyalgicE

The Mestinon/LDN Life Improvement Trial (LIFT) is seeking eligible research participants now within 300 miles of Brigham and Women’s Hospital at Harvard Medical School. Learn more about the LIFT: clinicaltrials.gov/study/NCT063...

OMF has now received approval from the NIH to access plasma samples collected via the Chronic Fatigue Initiative, bringing the total number of samples for our large-scale ME/CFS biomarker project (BioQuest) to 1,000. 👉 Read the latest BioQuest update: www.omf.ngo/bioquest-upd....

Adverse events are unwelcome occurrences that are associated with a medical intervention (e.g., drug, procedure). They may or may not be directly caused by the medical intervention—they can be caused by interactions with other drugs or other patient factors—and can vary in severity.

The 9th Annual Stanford Working Group Meeting on the Molecular Basis of ME/CFS started today. Today’s agenda is shown in the image. The Community Symposium will take place on Friday, September 5, from 8:00 am to 2:30 pm PST, and requires registration. Register 👉 ow.ly/Upnh50WPPbR.

Long Covid sky, do you know about CURE ID cure.ncats.io an FDA survey on meds you’ve trialed? Results could help show NIH there’s more to study than melatonin & computer games! But CURE ID needs 1000 reports to start crunching data! Will you take the survey—& ask a pal to join too? Here’s how! 🧵

OMF's Melbourne ME/CFS Collaboration published a paper on the results of a systematic review looking at cerebral blood flow in #MECFS and #orthostaticintolerance (OI). 118 studies, including over 9000 participants, were incorporated in the systematic review. ow.ly/QZjw50WNfjt

🧬Science Wednesdays: Cognitive testing Cognitive testing is a way of measuring different parts of brain function. Some of these parts of brain function include reaction time, processing speed, attention, working memory, and spatial processing. (1/3)

From our friends at @meactnet.bsky.social: 📢 Help Us Save Telehealth

ICYMI: OMF's research centers in Uppsala and Melbourne published a study of steroid hormones. The study identified changes in steroid-steroid relationships that indicate there is a dysfunction in HPA axis function and progestogen pathways. 👉 ow.ly/Hh1z50WvrLb

TREATME: the Open Medicine Foundation's Mammoth ME/CFS and Long COVID Treatment Survey Results www.healthrising.org/blog/2025/07... Includes a summary plus an audio version of the full article & separately of the summary #LongCovid #MEcfs #CFS #PwME @openmedf.bsky.social @cortjohnson.bsky.social

Please join the Community Symposium on the Molecular Basis of ME/CFS with opening remarks by Ronald W. Davis, PhD, Stanford University, followed by a welcome from Linda Tannenbaum, OMF CEO. 🗓️ September 5, 2025 ⏲️ 8:00 am – 2:30 pm PST 👉 Register here: ow.ly/9zRg50WIbO3.

From a Mother’s Love to a Global Movement: A Conversation with Linda Tannenbaum, OMF's Founder & CEO. Led by Catarina Santos, co-produced by Joana Ferraz of Millions Missing Aliança—both mothers impacted by #MECFS & #LongCOVID. Watch now👉 ow.ly/L1GL50WJxHW.

🧬Science Wednesdays: Neutrophils #Neutrophils are a type of white blood cell. They play an important role in the immune system, especially in fighting infections. Neutrophil dysfunction is associated with chronic inflammation, making them particularly relevant for #MECFS.