After two days on how to generate images, Stanford's Guolan Lu guided CCII workshop participants through what is arguably the most significant bottleneck: how to analyse all the resulting data (pic by @hiroshi-ichise.bsky.social) #Imaging #Immunology www.ccii.med.kyoto-u.ac.jp/en/event/eve...

With @hiroshi-ichise.bsky.social, closing the @ccii-kyoto.bsky.social workshop on advanced imaging and image analysis in Kyoto. Thanks to Guolan Lu (Stanford), @iannaconelab.bsky.social, Andrea Radtke (Leica), Yuki Sugiura (CCII), and Johanne T. Jacobsen for great lectures and practicals!

A Brief History of Everything (in imaging) with Oslo University's Johanne Tracey Jacobsen at CCII's workshop on Advanced Tissue Imaging and Image Analysis, followed by hands on work for the participants. #Immunology #Imaging www.ccii.med.kyoto-u.ac.jp/en/event/eve...

A Brief History of Everything (in imaging) with Oslo University's Johanne Tracey Jacobsen at CCII's workshop on Advanced Tissue Imaging and Image Analysis, followed by hands on work for the participants. #Immunology #Imaging www.ccii.med.kyoto-u.ac.jp/en/event/eve...

New paper from CCII researchers Masaki Tajima, Sidonia Fagarasan et al: a purine salvage pathway that helps CD8 T cells cope with metabolic stress and fend off ferroptosis. #Immunology #Metabolism @natimmunol.nature.com www.nature.com/articles/s41...

Matteo Iannacone @iannaconelab.bsky.social gave a tour de force presentation on liver immunity, hosted by @hiroshi-ichise.bsky.social as part of the CCII workshop on Advanced Tissue Imaging & Image Analysis #Immunology #TissueImmunity www.ccii.med.kyoto-u.ac.jp/en/event/eve...

Matteo Iannacone @iannaconelab.bsky.social gave a tour de force presentation on liver immunity, hosted by @hiroshi-ichise.bsky.social as part of the CCII workshop on Advanced Tissue Imaging & Image Analysis #Immunology #TissueImmunity www.ccii.med.kyoto-u.ac.jp/en/event/eve...

CCII's Kenji Chamoto introduces guest speaker Florent Ginhoux, who spoke on the heterogeneity of tumor associated macrophage #Immunology #Kyoto www.ccii.med.kyoto-u.ac.jp/en/

Deadline extended to March 27th for the CSHA conference on Bacterial Infection & Host Defense May 11-15, 2026! We have a fantastic list of speakers and opportunities for abstract talks. For full details, please visit the conference webpage: www.csh-asia.org?content/2975. Hope to see you in Suzhou!

⏰ Reminder: There’s still time to register & submit an abstract for the 21st International Conference on Innate Immunity! 🎓 Travel awards available 📅 May 22–27, 2026 | 📍 Kalimera Kriti Hotel & Conference Center 🇬🇷 #InnateImmunity #Immunology aegeanconferences.org/src/App/conf...

Our Imaging workshop organizer, Hiroshi Ichise, will be joining CCII this spring. You can read Hiroshi's recent work with Ron Germain, 'Rebalancing viral and immune damage versus repair prevents death from lethal influenza infection' (and see the beautiful images) 👇 www.science.org/doi/abs/10.1...

🧫 Working in pediatric infectious diseases? IIC 2026 takes place June 23–25, 2026, in Oxford, UK. Plenary sessions on key topics in pediatric infection, with lectures, case rounds & debate. Learn more: https://loom.ly/Qr7bMHM #ImmunologyWithoutBorders

Our Imaging workshop organizer, Hiroshi Ichise, will be joining CCII this spring. You can read Hiroshi's recent work with Ron Germain, 'Rebalancing viral and immune damage versus repair prevents death from lethal influenza infection' (and see the beautiful images) 👇 www.science.org/doi/abs/10.1...

Register for April's CCII Workshop on Advanced Tissue Imaging & Image Analysis, here in Kyoto. Org. by Hiroshi Ichise & supported by Leica. Invited faculty: Matteo Iannacone (San Raffaele), Johanne Tracey Jacobsen (Oslo), Guolan Lu (Stanford), Yuki Sugiura (CCII) & Andrea Radtke (Leica). It's free!

Register for April's CCII Workshop on Advanced Tissue Imaging & Image Analysis, here in Kyoto. Org. by Hiroshi Ichise & supported by Leica. Invited faculty: Matteo Iannacone (San Raffaele), Johanne Tracey Jacobsen (Oslo), Guolan Lu (Stanford), Yuki Sugiura (CCII) & Andrea Radtke (Leica). It's free!

Tetsuo Hasegawa from the LMB (Cambridge) will give a seminar at CCII (Kyoto) on March 25th on “Fenestrated capillaries and the sentinel macrophage-nociceptor unit in joint immunity” For more info. 👇 #Immunology #Immunotherapy www.ccii.med.kyoto-u.ac.jp/en/event/eve...

Brown was an early mentor to Tasuku Honjo, who's always acknowledged him (including in his Nobel lecture over 4 decades later, on a completely different topic) When we were creatin a small exhibition here in @ccii-kyoto.bsky.social, Prof Honjo insisted that it include Don Brown (pic is from a panel)

Tetsuo Hasegawa from the LMB (Cambridge) will give a seminar at CCII (Kyoto) on March 25th on “Fenestrated capillaries and the sentinel macrophage-nociceptor unit in joint immunity” For more info. 👇 #Immunology #Immunotherapy www.ccii.med.kyoto-u.ac.jp/en/event/eve...

MHC one–two punch knocks out #cancer. Amir Ghorbani and Jonathan Yewdell @niaidnews.bsky.social discuss new study by Zhang, Chamoto and colleagues @ccii-kyoto.bsky.social (rupress.org/jem/article/...) in Insights: rupress.org/jem/article/... #TumorImmunology #Immunotherapy

The Chamoto lab at CCII works on the interplay of metabolism, ageing, and immunity in the host response to tumors. Find out more about their research here 👇 www.ccii.med.kyoto-u.ac.jp/en/research/...

New paper from CCII: Active aldehydes accelerate CD8+ T cell exhaustion by metabolic alteration in the tumor microenvironment, by Yasuharu Haku, Kenji Chamoto et al in @natimmunol.nature.com #Immunology #Immunotherapy #Metabolism www.nature.com/articles/s41...

New paper from CCII: Active aldehydes accelerate CD8+ T cell exhaustion by metabolic alteration in the tumor microenvironment, by Yasuharu Haku, Kenji Chamoto et al in @natimmunol.nature.com #Immunology #Immunotherapy #Metabolism www.nature.com/articles/s41...

Here at @ccii-kyoto.bsky.social we had a workshop with @victora.bsky.social @danmucida.bsky.social Angelina Bilate (Rockefeller) & Carolina Lucas (Yale) where I asked them to discuss with the students & postdocs failed projects & negative results, including when to walk away from a project.

CCII's Sidonia Fagarasan & Kenji Chamoto recently discussed recent advances in tumor #metabolism & #immunity at the 2nd @csisingapore.bsky.social – Kyoto University Joint Symposium. www.ccii.med.kyoto-u.ac.jp/en/2025/11/2...

Senior Editor Zoltan Fehervari @nature.com recently stopped by CCII to discuss scientific publishing, some of its myths & legends, and what makes for a "good" paper. #ScientificPublishing #Immunology #Immunotherapy www.ccii.med.kyoto-u.ac.jp/en/events/

'The deal, announced on December 22, is to be signed off officially in 2026, but Japanese researchers and companies can already apply for calls starting in January and join projects on an equal footing with partners in the EU and other associated countries.' sciencebusiness.net/news/horizon...

Senior Editor Zoltan Fehervari @nature.com recently stopped by CCII to discuss scientific publishing, some of its myths & legends, and what makes for a "good" paper. #ScientificPublishing #Immunology #Immunotherapy www.ccii.med.kyoto-u.ac.jp/en/events/

New findings from Zhang, Honjo, Chamoto et al. @ccii-kyoto.bsky.social indicate that a subset of cancer cells expressing CTAs is sufficient to evoke overall antitumor immunity by broadening T cell responses to other neoantigens. rupress.org/jem/article/... #TumorImmunology

CCII Vice Director Sidonia Fagarasan introducing Michael Dustin (Oxford), who gave a great talk on the immunological synapse. For a list of upcoming seminars & events at CCII, visit our webpage. #Immunology #Immunotherapy www.ccii.med.kyoto-u.ac.jp/en/events/

What a great meeting, not sure who else I can on this platform other than @marcsdionne.bsky.social & @cbartman.bsky.social

CSI Singapore is excited to be here on BlueSky! 👋 Read up on cancer research breakthroughs, latest happenings, & events on this space. We hope you stay connected with us on our journey to make significant contributions in cancer research 👨‍🔬 linktr.ee/csi_singapore csi.nus.edu.sg/csi-singapor...

CCII's Sidonia Fagarasan & Kenji Chamoto recently discussed recent advances in tumor #metabolism & #immunity at the 2nd @csisingapore.bsky.social – Kyoto University Joint Symposium. www.ccii.med.kyoto-u.ac.jp/en/2025/11/2...

Congratulations @jcstark.bsky.social and the team, antibody-lectin chimeras (AbLecs), a new modality for cancer immune therapy, now published @natbiotech.nature.com. These bispecifics can block glyco-immune checkpoint receptor ligands directly at the immune synapse/activate immune effector functions

Participants emerge from the conference room into the bright sunlight of Naoshima Island in CCII's first international symposium on Cancer, Metabolism, and Immunity. CCII sponsored this small, intimate meeting where participants freely shared and discussed ideas & data in a beautiful setting.

These 2 landmark papers came out at the start of my PhD. Science and clinic. Literally back to back. It has been an enduring inspiration ever since to be a part of this wonderful experiment called immunology.

Participants emerge from the conference room into the bright sunlight of Naoshima Island in CCII's first international symposium on Cancer, Metabolism, and Immunity. CCII sponsored this small, intimate meeting where participants freely shared and discussed ideas & data in a beautiful setting.

Prof Tasuku Honjo is now the Director of CCII, our new center in Kyoto University, dedicated to deciphering anti-tumor immunity and discovering the next generation of cancer immunotherapies. www.ccii.med.kyoto-u.ac.jp/en/

In the same issue, Revy, Fischer and Durandy showed that the same gene, AID, was responsible for a mysterious form of hyper-IgM syndrome that was not linked to mutations in the CD40 pathway, demonstrating that AID also controlled CSR and SHM in humans. www.cell.com/fulltext/S00...

Muramatsu had previously reported the discovery of the AID gene in a screen. In the 2000 Cell paper, he and his collaborators in the Honjo lab, including Fagarasan demonstrated its function in mice. www.cell.com/AJHG/fulltex...

In a @cp-cell.bsky.social Benchmarks article, Masamichi Muramatsu, Sidonia Fagarasan et al tell the story of the discovery of AID in the Honjo lab, solving the decades long mystery of the molecular effector of Ig class switch recombination and somatic hypermutation. #Immunology

In a @cp-cell.bsky.social Benchmarks article, Masamichi Muramatsu, Sidonia Fagarasan et al tell the story of the discovery of AID in the Honjo lab, solving the decades long mystery of the molecular effector of Ig class switch recombination and somatic hypermutation. #Immunology

This #Preprint reports that B6 (but not wild mice) have a truncated PDL2, missing an active intracellular signalling domain: "Surprisingly, in C57BL/6J (B6) mice PD-L2 has only a 5-amino acid intracellular domain, and the same is true for several other laboratory mouse strains" #Immunology

It now greets visitors at CCII's main entrance hall, in our BMS building designed by Tadao Ando. To learn more about research, events, and opportunities at the Center for Cancer Immunotherapy and Immunobiology, follow the link below 👇 www.ccii.med.kyoto-u.ac.jp/en/

Mr Kamada's work features in several prestigious collections, including the @metmuseum.org www.metmuseum.org/art/collecti...

The CCII community has received a wonderful gift from master ceramicist, Mr. Koji Kamada The Tenmoku Bowl generously donated by the artists is currently on display in the main entrance hall of our BMS building in Kyoto. kogei.kyoto/artists/kama...

The CCII community has received a wonderful gift from master ceramicist, Mr. Koji Kamada The Tenmoku Bowl generously donated by the artists is currently on display in the main entrance hall of our BMS building in Kyoto. kogei.kyoto/artists/kama...

Chimeric MHC class I and II-restricted non-self epitopes broaden anti-tumor T cell reactions. New study from Rongsheng Zhang, Tasuku Honjo, Kenji Chamoto and colleagues @ccii-kyoto.bsky.social: rupress.org/jem/article/... #TumorImmunology

It was great having you here with us for your maiden voyage, Caroline. We hope the symposium lived up to your expectations!

In @jem.org, Zhang, Honjo, Chamoto et al. @ccii-kyoto.bsky.social identified peptide sequence principles that drive dendritic cell maturation and broaden tumor-reactive T cell clones, even with non-tumor sequences. rupress.org/jem/article/... #TumorImmunology

AID, happy 25th: www.sciencedirect.com/science/arti...