Tissue phase transitions in development: more than just mechanics In this Review, @nicolettapetridou.bsky.social, @laura-rustarazo.bsky.social and @karengrace12.bsky.social discuss tissue phase transitions during development: doi.org/10.1242/dev....

We are hiring! Join the Stapornwongkul lab as a Master's student to develop novel optogenetic tools and investigate how spatiotemporal metabolic dynamics affect patterning and morphogenesis of in vitro human gastrulation. Link below 👇

VGZT is back this Thursday with two exciting talks! 🎉 🗓️ Thursday, February 19th ⏰ 9:30 PST / 12:30 EST / 17:30 UTC / 17:30 GMT / 18:30 CET Our speakers are 👉 Raquel Fueyo (@fueyoraquel.bsky.social) 👉 Margarete Diaz Cuadros (@mdiazcuadros.bsky.social) See you on there! 👋

Two funded PhD positions investigating the evolution of sarcomeres @ibdm.bsky.social in @biancah0406.bsky.social and our lab, together with @cnidevo.bsky.social - Interested to explore how similar or different Jellyfish sarcomeres are to Drosophila or human ones? www.ibdm.univ-amu.fr/ibdm_job/2-a...

JOB ALERT! We are excited to announce that we are recruiting three new academics at lecturer level! Click the link below for more info on how to apply, and don’t forget to explore our research themes too! We look forward to receiving your applications! www.bristol.ac.uk/jobs/find/de...

Really excited to share our new paper in @nature.com! We uncovered how a physical instability of the cytoplasm coupled with the cell cycle drives cytoplasmic partitioning in early embryos #zebrafish #drosophila. Read more in this🧵 www.nature.com/articles/s41... 🤩 @poldresden.bsky.social @mpi-cbg.de

🎉 The Developmental Mechanics Seminar Series is back! 🗓️ Thurs, Jan 22 🎙️ Opening talks: 🧬Guy Tanentzapf (UBC) — How cell adhesion molecules wire into the cytoskeleton 🌀Juan Manuel Gomez Elliff (EMBL) @gomezjm-devmech.bsky.social — Mapping tissue mechanics with Brillouin microscopy

Using fluorescence live imaging and an in vitro implantation model, we show that human embryo attachment begins with direct cell fusion via syncytin-2–MFSD2A interaction. With @hansclevers.bsky.social. Great work by @tnoordzij.bsky.social & @martinacelotti.bsky.social www.biorxiv.org/content/10.6...

Super cool paper! Presomitic mesoderm, oxygen levels, segmentation clock

🚨Seeking developmental or cell biologists🔬!🚨 Our department @ucl-cdb.bsky.social is looking to support scientists seeking to establish their lab with a fellowship. Deadline: 30 Jan. Apply here: www.ucl.ac.uk/work-at-ucl/...

Congrats to the leading author @agrigas.bsky.social!

❗PREPRINT ALERT❗ doi.org/10.64898/202... The lab of M. Lisa Manning at @syracuseu.bsky.social in collaboration with Ale Mongera at @ucl-cdb.bsky.social show that in the avian presomitic mesoderm, Contact Inhibition of Locomotion has a tissue-wide effect, making tissue act like a fluid under tension.

Contact Inhibition coordinating tissues made sparsely of mesenchymal cells. From Alex Grigas @ ManningGroup and @mongeralab.bsky.social www.biorxiv.org/content/10.6...

Super cool work spearheaded by the amazing @agrigas.bsky.social! Excited for this collaboration with @manningresearch.bsky.social and for everything still to come! 🎉 Also thank you to @emaniou.bsky.social and @glgalea.bsky.social for your help!

Very excited about this new paper out on bioRxiv, spearheaded by the fantastic Dr. Grigas in collaboration with @mongeralab.bsky.social and Galea labs.

Check out this new preprint on PSM mechanics! Very nice work!

How do sparse mesenchymal cells, with unique stellate arms spanning large gaps between cells, maintain their network while still flowing during development? In our new preprint we describe the avian PSM as a fluid under tension and develop new theory to explain it: www.biorxiv.org/content/10.6...

With more than 2.1k citations, 'The identification of genes with unique and essential functions in the development of the zebrafish, Danio rerio' by the CNV Lab highlighted the arduous work that took place during 'The Big Screen'. In total, 1163 mutants were described. #ZebrafishFunFacts 🧪

So called microtubule organizing centers (MTOCs) are not "organizing centers". They don't control their position (network center), nor MT orientation, length and shape (network shape). The actual organizers are MTs, molecular motors and regulators of MT +ends. MTOCs nucleate MTs. Let's rename MTOCs.

Thought I was being really novel when I designed and 3D printed this mold for zebrafish transplants based on the microinjection one, but found out today it already exists… Bottom: my PLA mold that’s bent from warm agarose Top: a very kind (more robust looking) gift from @mongeralab.bsky.social

Cell type-independent timekeeping gene modules enable embryonic stage prediction in zebrafish https://www.biorxiv.org/content/10.1101/2025.11.12.688039v1

Stationary and germ layer-specific cellular flows shape the zebrafish gastrula https://www.biorxiv.org/content/10.1101/2025.11.10.687746v1

How can we organize current theoretical approaches for developmental biology - from information to dynamical systems & GRNs - into a common framework? We propose to think along Marr's 3 levels: computational problem, algorithm, implementation Check out our review: arxiv.org/abs/2510.24536

We are looking for: PhD Student (starting as Research Assistant) and Postdoctoral Researcher in Stem Cell Biology and Mechanobiology. Please RT💕 🔗 About our lab: renew.science/principal_in... 🎓 PhD position: jobportal.ku.dk/phd/?show=15... 🧪 Postdoc position: jobportal.ku.dk/videnskabeli...

🚨 Come join us @sheffielduni.bsky.social for a PhD on the evolution and development of feathers and flight! 🐣🔬 This project is supervised by @matt-towers.bsky.social & @alexgfletcher.bsky.social, and I'm excited to be involved as a project advisor. Please share! www.findaphd.com/phds/project... 🧪

Had the pleasure of working with @mohannad-dardiry.bsky.social to rethink what it means to develop for life. Many thanks to @dev-journal.bsky.social! @embl.org #LifelongDevSI

Happy birthday to #LaskerLaureate Christiane Nüsslein-Volhard! She identified 120 genes involved in specifying embryonic pattern development. Read about the epic screen that yielded her Lasker Award-winning results: ow.ly/Pz2050PYFsz #WomenInSTEM 🧪

We are hiring ! If you want to become professor of Bioinformatics in the best city of North America, check the announcement below ! Also you do need to speak French (as long as you commit to learning it :) ) www.umontreal.ca/public/www/d...

Can pressure gradients persist over long timescales in animal cells? We induced intracellular pressure gradients and examined the resulting flows in single cells. We reveal surprisingly long lasting pressure gradients. More here: elifesciences.org/reviewed-pre...

Super cool! Looking forward to trying this reporter!

📣Our project, “Mechanometabolic Control of Vertebrate Limb Elongation,” has been funded by Wellcome! Over the next 8 years, we’ll collaborate with @manningresearch.bsky.social and Nathalie Agar’s group to understand the mechanics of ECM-rich mesenchymal tissues! Funded positions available!🎉

Everything (and more) you wanted to know about Nodal Signaling. A Paradigm for TGFβ Signaling in Embryonic Development | Annual Reviews - www.annualreviews.org/content/jour...

Few spots left on our @bcube-tud.bsky.social organised hashtag #Symposium: Engineering Life 2025: Origin and Function of Mechanical Forces in Biology ⚙️🧬 📆 September 1-3, 2025 📍 Steigenberger Hotel de Saxe, Dresden Register now (Deadline 31 July 2025): engineering-life-dresden.de

After 15 years of controversy, @science.org retracts ‘arsenic life’ paper

Somatic cells compartmentalise their metabolism to sustain germ cell survival https://www.biorxiv.org/content/10.1101/2025.07.22.666113v1

Great thread by @amichaut.bsky.social

Check out this thread I wrote for @epimechfc.bsky.social ⬇️

SARCOMERES divide! Mechanism how muscles grow while contracting - daughter sarcomeres appear everywhere. Seen live, registered on our cover. Pioneered by @clementrodier.bsky.social @friedrich-group.bsky.social Ian Estabrook @ibdm.bsky.social $ by @hfspo.bsky.social www.science.org/doi/10.1126/...

Why do vertex models work so well to predict tissue fluidity/rigidity, even though they are simple and possibly even wrong? A new paper in PRX Life @prxlife.bsky.social, spearheaded by @sadjadarzash.bsky.social and Ojan Damavandi, suggests universality may explain: journals.aps.org/prxlife/abst...

SAVE THE DATE!! #2026SDB 🧪🧬🔬🧫🎉 (Never been to Vegas 😂 Exciting!!)

The Company of Biologists Workshop - Mechanometabolism Unleashed: The Interface of Cell Mechanics and Metabolism Thank you to Workshop organisers Marco Foiani, Ana-Maria Lennon-Duménil, Victoria Sanz-Moreno and Giorgio Scita. #Workshop #Biology #CellBiology #Community #Collaboration #Research

A closed feedback between tissue phase transitions and morphogen gradients drives patterning dynamics https://www.biorxiv.org/content/10.1101/2025.06.06.658228v1

Beautiful work as always from the @bhamlalab.bsky.social ! Flamingoes use swirling flows to trap and catch preys!

📢 Fresh off the press and featuring new exciting experiments! 🧪 We show how glycolytic activity instructs germ layer proportions through regulation of Nodal and Wnt signaling - happy to finally share this 😊 doi.org/10.1016/j.st... B2B with @jesseveenvliet.bsky.social lab: doi.org/10.1016/j.st... 🤩

We're disappointed to see Ben Barres's powerful book "The Autobiography of a Transgender Scientist" among the ~400 titles removed from the Naval Academy Library. Needless to say, we're proud to have published his book and will keep it — and his memory — alive.

Thrilled to share our new review article! “The role of extracellular matrix viscoelasticity in development and disease” written together with Olivia Courbot is now published in npj Biological Physics and Mechanics. www.nature.com/articles/s44... #ECM #Mechanobiology #DevelopmentalBiology

Amen

Curious about how percolation theory enable understanding the impact of mechanical heterogeneity in model breast cancer cells check this by Leo Camillo Chiara and joseph #giavazzi, #Voituriez doi.org/10.21203/rs....

🔗 You can read the full story here: www.biorxiv.org/content/10.1... #DevBio #Mechanobiology #Biophysics

🚨 Paper Alert 🚨 Absolutely delighted to share our last paper on "spatial mechano-transcriptomics" @naturemethods👇!! www.nature.com/articles/s41...