elisa
@mildtin.bsky.social
📤 1417
📥 1100
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Usually a lurker, Chronically Online for
#LongCovid
and other
#IACC
| Australia
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elisa
Joey Politano🏳️🌈
5 months ago
Some good news—official data released today shows US solar generation continues to grow rapidly and is on track to set new record highs. In March, solar output was up 35% compared to the same time last year!
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Miles W. Griffis
5 months ago
Akiko Iwasaki and Harlan Krumholz call for Long COVID and chronic disease research funding in the WSJ: “Advancing this research is one of the most effective ways to improve the lives of the tens of millions of Americans with chronic diseases.”
www.wsj.com/opinion/how-...
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Opinion | How to Lead a Chronic Disease Revolution
Washington has an opportunity to help tens of millions.
https://www.wsj.com/opinion/how-to-lead-a-chronic-disease-revolution-research-covid-infection-congress-d304d2ac?st=AfuZ7E&reflink=desktopwebshare_permalink
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It's ME(Jaime)
6 months ago
This is full of really useful information about
#LongCOVID
. Congrats,
@patientled.bsky.social
!
rehabcovidnetwork.med.utoronto.ca/news/patient...
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Patient-Led Research Collaborative Launches Fact Sheet
https://rehabcovidnetwork.med.utoronto.ca/news/patient-led-research-collaborative-launches-fact-sheet
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Just sent off bloods for another LC diagnostic study - if you're in Melbourne, Perth or Brissie and haven't participated yet please sign up! They do home visits for housebound folks
6 months ago
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thetranscendedman
6 months ago
In Italy, muscle biopsies from 8 COVID-19 survivors revealed a distinct myopathy marked by damaged blood vessel linings, not seen in steroid-related muscle disease, suggesting long COVID muscle weakness stems from vascular injury, not direct viral attack.
www.tandfonline.com/doi/full/10....
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Muscle disease in severe COVID-19 patients: a microangiopathic myopathy
Patients surviving coronavirus disease of 2019 (COVID-19) often complain of skeletal muscle weakness that may be very limiting and long-lasting. There are almost no studies on the skeletal muscle o...
https://www.tandfonline.com/doi/full/10.1080/01913123.2025.2488809
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In the next year or so, I'm hoping that we'll have the results for - Nanoneedle validation study - Several pilot / case studies for mAbs in Long Covid - Early signals from one or more of the JAK-STAT trials (Abrocitinib, Upadacitinib)
6 months ago
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thetranscendedman
6 months ago
Chan Soon-Shiong Foundation will expand PolyBio’s long COVID research with new funding. Support targets SARS-CoV-2 persistence in tissue and its potential role in cancer development. Thank you, @DrPatSoonShiong
polybio.org/chan-soon-sh...
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Chan Soon-Shiong Family Foundation donation expands PolyBio Long COVID program - PolyBio Research Foundation
Funds will support exploration of SARS-CoV-2’s potential to drive cancer, as well as continued work delineating persistence of the virus in...
https://polybio.org/chan-soon-shiong-family-foundation-donation-expands-polybio-long-covid-program/
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elisa
Naomi Alderman
6 months ago
goddd the number of things that turn out to be caused (at least partly) by infectious, vaccinatable diseases. apparently some dementia is actually "long chickenpox"?
www.theguardian.com/society/2025...
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Study finds strongest evidence yet that shingles vaccine helps cut dementia risk
Older adults in Wales who had the jab were 20% less likely to be diagnosed with dementia that those not vaccinated
https://www.theguardian.com/society/2025/apr/02/study-finds-strongest-evidence-yet-that-shingles-vaccine-helps-cut-dementia-risk
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elisa
AndreaaaHHhHHHHh!! Grimes
6 months ago
But I've been following politics and organizing long enough to know that the Left has a real tendency toward "thing 1 didn't work, everything sucks and is worthless" and all I can tell you is that the Right does not believe that and their success is largely due to their absolute asshole persistence.
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Billy Hanlon
6 months ago
Dr. Soon-Shiong: “…is this what I call long COVID, virus persisting?..the group at UCSF has now definitively proven…does that COVID virus suppress the natural killer cell?…it becomes what-you-call-energic? That's now been published. The natural killer cell has gone to sleep."
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Jess Nevins
7 months ago
h/t to Greg Morrow for this-- They cured symptomatic rabies in mice. RABIES.
www.embopress.org/doi/full/10....
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mAb therapy controls CNS‐resident lyssavirus infection via a CD4 T cell‐dependent mechanism | EMBO Molecular Medicine
image image Rabies is a fatal viral disease of humans, with uniform mortality once central nervous system (CNS) invasion occurs and symptoms appear. This study demonstrates that a single‐dose monoclon...
https://www.embopress.org/doi/full/10.15252/emmm.202216394?fbclid=IwY2xjawJTn45leHRuA2FlbQIxMAABHaXTFJkuTsqzhgFDvqIYsN22IG_dbCPzYFrjqvaP-3ogTX88PlI51jYohQ_aem_0QsgcT-b8tUUHDaBNLeZQw
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Long COVID Campaign | www.longcovidcampaign.org
7 months ago
🚨THANK YOU
#LONGCOVID
PATIENT COMMUNITY 🚨 Because of you, NIH RECOVER grant terminations being reversed & restored! This win was only possible due to YOUR advocacy & support from our Hill bipartisan champions! THANK YOU to every person who called, emailed & took action!
#NoLongCOVIDCuts
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elisa
Max Kozlov
7 months ago
NIH, which began this week terminating projects studying long COVID, has reinstated the grants, after pressure from Sen. Todd Young's (R-IN) office, an HHS source tells me. Young had secured a commitment from RFK Jr that he'd continue funding long COVID research. Story by
@thesicktimes.bsky.social
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UPDATE: RECOVER Long COVID pathobiology grants restored - The Sick Times
Long COVID research grants from the National Institutes of Health’s RECOVER program will be restored following news stories about their abrupt cancellations and advocacy to restore the funding, accord...
https://thesicktimes.org/2025/03/28/update-recover-long-covid-pathobiology-grants-restored/
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elisa
Rowan Walrath
7 months ago
NEW: The NIH appears to be reversing course on its decision to abruptly cancel a spate of grants for
#longCOVID
research earlier this week.
@cenmag.bsky.social
#chemsky
#biosky
cen.acs.org/policy/resea...
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NIH restores some long COVID grants
Researchers still nervous about funding status
https://cen.acs.org/policy/research-funding/NIH-restores-long-COVID-grants/103/web/2025/03
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elisa
Miles W. Griffis
7 months ago
🚨 BREAKING: Long COVID research grants rescinded earlier this week have been restored, according to researchers & patient reps. Advocates organized quickly yesterday in response to the news, helping reverse the decision. Exclusive in
@thesicktimes.bsky.social
thesicktimes.org/2025/03/28/u...
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UPDATE: RECOVER Long COVID pathobiology grants restored - The Sick Times
Long COVID research grants from the National Institutes of Health’s RECOVER program will be restored following news stories about their abrupt cancellations and advocacy to restore the funding, accord...
https://thesicktimes.org/2025/03/28/update-recover-long-covid-pathobiology-grants-restored/
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elisa
Melissa Mazur
7 months ago
Thank you Senator Todd Young (R-IN), Senator Bill Cassidy (R-LA),
@kaine.senate.gov
@sanders.senate.gov
for your help here! Bipartisan coordinated efforts like this are crucial to support constituents and the world community👏👏👏 Appreciate your leadership!!!
#LongCovid
#NoLongCOVIDCuts
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elisa
Mike Masnick
7 months ago
Fight back against all their nonsense. Sometimes it works.
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elisa
Patient-Led Research Collaborative
7 months ago
The elimination of: grants to study
#LongCovid
, the Office of LC, & Advisory Committee on LC — have sent a chilling signal. We encourage folks to take the following action led by our partners: 1. Call your reps:
win.newmode.net/longcovidcam...
2. Email your reps:
actionnetwork.org/letters/long...
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DOGE cuts can and do get reversed but ONLY if there is LOUD and IMMEDIATE pushback E.g. FDA medical devices reviewers reinstated a week after being let go - it's possible and it needs to happen for LC Call your reps make sure they hear from us!!
7 months ago
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Chise
7 months ago
THIS IS HUGE! Researchers at Scripps Research Institute have developed a groundbreaking UNIVERSAL coronavirus vaccine that triggers STONG immune responses AND shows promise in neutralizing MULTIPLE coronaviruses, including those responsible for causing COVID-19, MERS, AND even the “common cold.” 🧪🧵⬇️
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elisa
It's ME(Jaime)
7 months ago
The administration has canceled 45 RECOVER
#LongCOVID
grants. These grants examined pathology, & were vital to understanding infection-associated chronic illness as a whole. Half of those with
#LongCOVID
at 6 mo. meet criteria for
#MECFS
. 🧪
cen.acs.org/policy/resea...
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NIH cancels grants through flagship long COVID initiative
Termination ‘a waste of the money we’ve spent already’
https://cen.acs.org/policy/research-funding/NIH-cancels-RECOVER-grants-long/103/web/2025/03
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US friends please call your reps 😭🙏 the only hope for saving these grants 🕯
bsky.app/profile/lcca...
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7 months ago
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Melissa Mazur
7 months ago
#pwLC
#pwME
#NEISVoid
please share with family and friends too! 👇
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#MEAction Network
7 months ago
#MEAction
plans to announce our
#MillionsMissing
campaign next week in which we will rally our community to fight back against these research cuts. TAKE ACTION now by calling your Congressional reps to tell them to STOP the CUTS! See the Long COVID Campaigns toolkit:
bit.ly/427IHlE
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Long COVID Campaign | www.longcovidcampaign.org (@lccampaign.bsky.social)
🚨BREAKING: NIH RECOVER #LongCOVID GRANT CUTS HAVE STARTED🚨 The next 2⃣ DAYS critical to tell Congress #NoLongCOVIDCuts to clinical trials & clinic funding. Can you make just 3⃣ calls & send 3⃣emails t...
https://bit.ly/427IHlE
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elisa
Long COVID Campaign | www.longcovidcampaign.org
7 months ago
🚨BREAKING: NIH RECOVER
#LongCOVID
GRANT CUTS HAVE STARTED🚨 The next 2⃣ DAYS critical to tell Congress
#NoLongCOVIDCuts
to clinical trials & clinic funding. Can you make just 3⃣ calls & send 3⃣emails today? ☎️Call Congress Tool
bit.ly/NoLongCOVIDC...
📨Email Congress Tool
bit.ly/NoLongCOVIDC...
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elisa
Dr. Lucky Tran
7 months ago
Update on Long COVID research funding: Per researcher and advocate
@themegascope.bsky.social
, funding for at least 45 different RECOVER studies have been terminated. RECOVER is a $1.7 billion program that serves as the single largest federal funding mechanism for long COVID research.
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emily fraser 🌿🐌✨
7 months ago
Please make calls to save Long Covid funding! As
@ezra.zone
has pointed out, it’s not just a few years of research being lost, it’s a generation of researchers who will move on to other issues that have funding… ie less hope this gets solved in our lifetimes 💔
win.newmode.net/longcovidcam...
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thetranscendedman
7 months ago
Beerse, Belgium. In cell and hamster models, researchers found that JNJ-9676, a small molecule targeting the SARS-CoV-2 membrane protein, blocks virus assembly and sharply reduces viral load, offering a new antiviral strategy.
www.nature.com/articles/s41...
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A small-molecule SARS-CoV-2 inhibitor targeting the membrane protein - Nature
JNJ-9676—a small-molecule inhibitor targeting coronavirus M protein that shows excellent efficacy in Syrian golden hamster models—binds to and stabilizes the M protein dimer in an altered conformation...
https://www.nature.com/articles/s41586-025-08651-6
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elisa
thetranscendedman
7 months ago
Leuven researchers screened 350,000 compounds and found CIM-834, a small molecule that blocks coronavirus assembly by locking the M protein in its inactive form. In mice and hamsters, it stopped SARS-CoV-2 replication and even prevented transmission.
www.nature.com/articles/s41...
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A coronavirus assembly inhibitor that targets the viral membrane protein - Nature
High-throughput screening and hit optimization have led to the development of a small molecule, CIM-834, that targets the SARS-CoV-2 membrane protein and blocks assembly of the virus.
https://www.nature.com/articles/s41586-025-08773-x
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elisa
Nature Portfolio
7 months ago
A paper in Nature Communications reports PET/CT-based in vivo imaging to track SARS-CoV-2 biodistribution in a COVID-19 non-human primate model using a radiolabeled human antibody revealing persistent detection in the lung and brain three months after infection.
#medsky
🧪
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Whole-body visualization of SARS-CoV-2 biodistribution in vivo by immunoPET imaging in non-human primates - Nature Communications
There are limited approaches to monitor virus spread in vivo. Here, the authors report PET/CT-based in vivo imaging to track SARS-CoV-2 biodistribution in a COVID-19 non-human primate model using a radiolabeled human antibody revealing persistent detection in the lung and brain 3 months after infection.
https://go.nature.com/42q1V6r
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elisa
Olenka Sayko
7 months ago
🚨 🚨 🚨 Really important action for
#LongCOVID
community and allies! Call or email your federal legislators to let them know
#NoLongCOVIDcuts
! This condition impacts millions of Americans, many of whom are severely disabled with NO treatments!
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Americans - long covid patients across the world are counting on you, please write and call! 💖
bit.ly/NoLongCOVIDC...
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7 months ago
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elisa
MEActMaryland
7 months ago
Another action to support
#LongCovid
. This one includes a phone call kit.
#NoLongCovidCuts
!
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elisa
Long COVID Campaign | www.longcovidcampaign.org
7 months ago
The next 3⃣ DAYS are critical to ensuring
#NoLongCOVIDCuts
to U.S. government
#LongCOVID
clinical trials & clinic funding. Can you make just3⃣ calls & send3⃣ emails to Congress today? ☎️Call Congress Tool☎️
bit.ly/NoLongCOVIDC...
📨 Email Congress Tool📨
bit.ly/NoLongCOVIDC...
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elisa
Long COVID Campaign | www.longcovidcampaign.org
7 months ago
📣
#LongCOVID
Community: With recent news, we're now hearing NIH RECOVER-TLC research & AHRQ Long COVID clinic funding could also be at risk. So LCC is launching a rapid-response campaign NOW to make it easier to call Congress & ask for
#NoLongCOVIDCuts
1/x
bit.ly/NoLongCOVIDCutsCall
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Riemerville
7 months ago
🚨 Long Covid funding is at risk! 🚨 Nobody is safe,Long Covid doesn’t discriminate.It could happen to you or someone you love. Please take 2 minutes to call your rep.& demand they keep Long Covid research funded. 📞 Call now:
win.newmode.net/longcovidcam...
#LongCovid
#NoLongCovidCuts
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elisa
Eric Topol
7 months ago
In <24 hours, Covid funding is DOGEd across HHS, CDC, NIH as if it and Long Covid didn't exist and there is no worry for future pandemics
www.science.org/content/arti...
www.nbcnews.com/health/healt...
www.science.org/content/arti...
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I'm only a couple of pages into Abundance but it's already making me emotional - my whole life we talked about how people last century would predict a future where we only had to work 10 hours a week, or sought to eradicate child poverty - always as things people tried in a bygone era
7 months ago
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The clouds change and so I still get a taste of wonder. In my little box in the sky
7 months ago
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emily fraser 🌿🐌✨
7 months ago
5 years. The only thing more traumatic than losing your life to a pandemic is being judged, mocked, & abandoned for it. If I look a little dead behind the eyes, that’s because I am 😵💫
#LongCovidAwarenessDay
#5YearsLongCovid
#HalfADecadeOfNeglect
#LongCovidAwarenessDay2025
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thetranscendedman
7 months ago
Netherlands, 151 participants. A 24-week trial found that daily vitamins K2/D3 reduced Long COVID symptoms, fungal translocation, and inflammation compared to standard care.
www.croiconference.org/abstract/644...
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337 - Vitamins K2 and D3 Improve Long COVID Index, Fungal Translocation, and Inflammatory Biomarkers
Background Long COVID (LC) is characterized by recurrent, prolonged, and new symptoms of COVID-19 at least 3 months after a SARS-COV-2 infection. LC was associated with fungal translocation, gut dysfu...
https://www.croiconference.org/abstract/644-2025/
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elisa
Tom Kindlon
7 months ago
.
@meresearchuk.bsky.social
: NK cells are immune cells that destroy infected/diseased cells i.e. possess cytotoxicity (ability to kill other cells).A study found - the most consistent immune finding in
#MECFS
research is reduced NK cell cytotoxicity,suggesting immune dysfunction
bit.ly/3F4cLqy
#cfs
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elisa
Tom Kindlon
7 months ago
From Brazil: Involvement of oxidative stress in post-acute sequelae of COVID-19: clinical implications
www.tandfonline.com/doi/full/10....
"findings suggest that individuals with PASC pronounced [oxidative stress], which potentially exacerbates disease complications."
#LongCovid
#PASC
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What do we owe each other? The answer is probably something like this
7 months ago
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elisa
Chise
7 months ago
THIS IS HUGE! Researchers at Stanford University have developed a dual-antibody treatment that remains effective against ALL SARS-CoV-2 variants by targeting a less-mutable part of the virus. This breakthrough could lead to longer-lasting therapies that OUTPACE viral evolution. 🧪🧵⬇️
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elisa
Billy Hanlon
7 months ago
New York Times: “30 Charts That Show How Everything Changed…in March 2020” “The number of people reporting a disability soared. Many Americans struggled with long Covid and reported cognitive issues like “brain fog”
www.nytimes.com/interactive/...
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I'm hoping that as we get further from 2020 and less people are having immediate, visceral reactions to thinking about the pandemic, it'll get easier again to talk about it, Long Covid, and preparing for the next one
7 months ago
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TSLA almost back down to where it was pre-election
7 months ago
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One silver lining of DOGE is that everyone is getting a crash course on the public service and what it actually does
7 months ago
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"[STIMULATE-ICP] has completed successfully, with results expected towards late April or early May." STIMULATE-ICP trialled rivaroxaban, colchicine, and famotidine/loratadine
www.theguardian.com/society/2025...
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‘We’re losing decades of our life to this illness’: long Covid patients on the fear of being forgotten
Five years on from March 2020, millions of people still face debilitating symptoms, with huge repercussions on public health and productivity. But politicians are starting to pretend the pandemic neve...
https://www.theguardian.com/society/2025/mar/02/were-losing-decades-of-our-life-to-this-illness-long-covid-patients-on-the-fear-of-being-forgotten
7 months ago
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