This! Fancy web interfaces let you explore the data, but they are not the same as sharing the data. You can do both!

New: GWAS of serurm antibody levels. Interesting findings include genetically correlated traits with hard-to-find shared causal variants, and apparently genetically uncorrelated traits sharing causal variants that operate in inconsistent directions www.medrxiv.org/content/10.1...

This is a perennial issue with grant applications. They want to support blue sky, ground breaking research, but do not want to maintain the useful tools that result from such research. Science cannot build and grow without sustaining our foundations.

You never know which straw will break the camel's back. This, it turns out, is mine. The Tory shadow home sec gives a frankly racist statement about deporting people here legally in order that we have a mostly "culturally homogeneous" population. Just horrific. /1

Given Lam's appalling comments, the UK government needs to make it free for those with permanent leave to remain to obtain British citizenship, to promote people making the change, and to make it quicker. They need to do that to remove understandable anxiety.

I'm very excited to be attending my first #ASHG25 this week! Come find me at poster board 1090F to talk about flexible and efficient eQTL mapping with quasar!

The PhD opportunities in our group and in many others at @mrc-lms.bsky.social are now open! lms.mrc.ac.uk/work-and-stu...

📣Preprint alert - a tricky one, as there are no significant results (and we all know null-results are hard to publish) Do PCSK9 levels affect survival in breast cancer patients? We tried to replicate findings in cell lines and mouse model using 3 Mendelian Randomization approaches, but failed.

This type of thread is so important to those preparing to leave school and trying to decide what university courses to consider. We could do something similar for #maths! /1

Many recent cyber attacks on business suggest digitised systems lack security and resilience. In a parallel world, AI is going to increase efficiency. Surely further increases in digitisation and joined up systems are required for AI to attempt this. How does that square with security & resilience?

You’re right, Ms Mahmood - I don’t. Because the slippery slope we’ve been going down has been spine chilling. It started with “illegal migrants.” That was the “reasonable concern” Just the law, nothing more. Politicians said, “people aren’t anti-immigration, they just want the rules respected.”

Dear parents - Yes you can give your sick child paracetamol if they’re >3 months old. It’s an excellent painkiller. It brings down a high temperature. It’s one of the safest drugs available. You are right to want to soothe your child’s distress. Evidence supports your good parenting. Be confident.

When you have to draw up schematic diagrams, what do you use? I vary between tikz, R, and PowerPoint, but they all have different advantages. None ever seems fully satisfactory.

There are just too many interesting papers and too little time...

In modern datasets, very large sample sizes combined with slight differences in information across SNPs (eg die to imputation) can mislead fine mapping algorithms, and in turn colocalisation.

NHS guidelines stand In the UK, paracetamol (acetaminophen in USA) is the first choice of painkiller if you're pregnant. It's commonly taken during pregnancy and does not harm your baby www.nhs.uk/medicines/pa...

New MPhil course starting @UniversityofCambridge. Exciting opportunity for Translational Medical Research in 🔬 Translational immunology 🌍 Pandemic preparedness ❤️ Cardiovascular and respiratory biomedical research 🏥 Acute and emergency care Apply here www.med.cam.ac.uk/study/mphil-...

Really looking forward to this

In 25 days time..... #2025PumphandleLecture Find out more:

📢 Applications are now open for our new MPhil in Translational Medical Research! Get hands-on experience from world leaders in immunology, pandemic preparedness, cardiovascular & respiratory biomedicine, and acute & emergency care. 👉 buff.ly/gH9tRV7 @cam.ac.uk

The exports the UK doesn't want... www.ft.com/content/758b...

👇👇👇 deadline for applying to this awesome opportunity is coming up on Friday Sept 12th! www.baker.edu.au/career/head-...

I can

Our paper is now out in #Statistics and Computing 🥳 With Paul Kirk & @chr1sw.bsky.social, we propose OG-SSLB, a biclustering method that integrates disease outcomes into the clustering process, improving interpretability & accuracy. Read: link.springer.com/article/10.1007/s11222-025-10709-4

Excited to see our (w/ @chr1sw.bsky.social) work published in @natcomputsci.nature.com! We developed a new framework, surrogate functional false discovery rate (sffdr), that integrates summary statistics of related traits to improve power in GWASs. Paper: www.nature.com/articles/s43...

Universities make a loss on home teaching. They make a loss on state-sponsored research. Now they will make a loss on international students. So there will be no activities at all that even break even. In those circs you cannot continue: the end. www.timeshighereducation.com/news/deficit...

Expressions of Interest OPEN for #BattenDisease Grant Round. The top priority research lines are so inspiring: best gene-targeted #therapy? which valid, reliable #biomarkers? Can disease progression be halted or reversed? Apply here: bdsrafoundation.org/wp-content/u...

An abbreviation (ABB) in a journal article (JA) or Grant Application (GA) is rarely worth the words it saves. Every ABB requires cognitive resources (CR) and at my age by the time I'm halfway through a JA or GA I no longer have the CR to remember what your ABB stood for.

No, Microsoft, YOU need to sign in again

The "assertion - evidence slide". Now I have a name for my favourite kind of slide. 100% agree on it's effectiveness for structuring a talk.

Are you looking for a statistics/ML postdoc? Come to work with @antonis02.bsky.social and me in the NEMO study, an international collaboration aiming to detect ovarian cancer earlier through cutting-edge multi-omics, funded by the Alliance for Cancer Early Detection. www.cam.ac.uk/jobs/researc...

ChatGPT 5 boasts it can function at PhD level, “ask me anything”. Spouse inputs the title of his own PhD, says please write me a PhD on this topic. ChatGPT5 immediately crashes. Recovers, then produces a page of articulate garbage citing plausible-sounding but incorrect sources.

This is how you can save intermediate stages of #tidyplots by using `save_plot()` in the middle of a pipeline 💡 #rstats #dataviz #phd

This will be a great lecture from a brilliant and impactful epidemiologist

Tip for presentations: avoid saying "I don't think this audience needs an introduction to X". Try instead giving a v brief introduction tailored to the key points you will reference in the rest of the talk. So often people assume I have knowledge I don't, and this hurts my ability to follow.

“Give people their flowers while they’re alive.”

What do people use for references in Google docs/word? Coming from latex where referencing was solid, have been stung a couple of times by Google docs/zotero losing or messing up which paper each reference number points to. This is too painful to go through again. What are the alternatives?

This summer, we are privileged to have a fantastic group of interns with us for eight weeks. They are each working with our researchers on projects and experiencing life at our Unit. It's great to have you all with us 😀

It has taken medical science 200 years to advance humans to the point where people are so healthy and living so long that they can deny that science and medicine is what got us here.

🚨 Job alert! We're hiring a Computational Biologist/Data Scientist within the Cambridge-GSK Translational Immunology Collaboration (CG-TIC). Join us to help translate discoveries into impact on chronic kidney and respiratory disease. Apply by 20 August: buff.ly/FFuvIx2 @cam.ac.uk

Devastating

An entire day on one plot. And I don't even love it...

Very excited to share new work from my PhD on a new software package for eQTL mapping: quasar. The quasar software package is a C++ program designed to provide a flexible and efficient eQTL mapping. www.medrxiv.org/content/10.1...

Booking is now open for the MRC #Biostatistics Unit's 22nd Armitage Day! Keynote from Matthew Stephens: “The menagerie of matrix factorization methods” Plus talks by @manuelazucknick.bsky.social, Gibran Hemani and (as yet unnamed!) BSU researchers. onlinesales.admin.cam.ac.uk/conferences-...

🎉Congratulations to Professor Ziad Mallat for winning the 2025 Louis & Artur Lucian Award for his groundbreaking work in cardiovascular immunology! Read more⬇️ @vpd-hlri.bsky.social @cam.ac.uk @mcgill.ca

Just sometimes, when you write an email to an unknown scientist hoping they might share some data that you are not completely sure they even hold, you get a simple "yes, happy to share and discuss the context of the data with you" in response. Happy day #openscience #sharingiscaring

‘MMR vaccination uptake rate for children by the age of five in Liverpool is just 73% ... The World Health Organisation says a threshold of 95% is needed to achieve herd immunity’ Please protect child by allowing them to be vaccinated. If you are worried, talk to your doctor. Misinformation kills.