It seems I see new announcements of university redundancies every few days. Science and scholarship may not be under attack in this country, but with no government response, they are under neglect.

Postdoctoral job announcement: come to Cambridge and work on population genetic modelling with environmental and ancient DNA, jointly with @gamzeandgursoy.bsky.social and me. Details at www.jobs.cam.ac.uk/job/55580/ - applications by June 16th.

Newly elected both as a Fellow of the @acmedsci.bsky.social and Fellow of the @royalsociety.org, John McCafferty has spent more than 3 decades transforming antibodies from natural defenders into medicines that have improved millions of lives. Read our latest feature on his journey: buff.ly/3GBB3Et

"Student's t-test" was developed by William Sealy Gosset, English chemist & head brewer at Guinness Brewery. He developed statistical methods under pseudonym "Student": t test, z distribution. He looks... exactly like you'd think the person who invented the t-test would look. *Significantly* so.

Looks like we've passed peak academia. www.ft.com/content/8097... via @data.ft.com

Every summer I repost this article on how to spot drowning. Please read it and pass on. In the last few years I’ve had SIX messages from people who saved a kid’s life after clicking on the link from my feed. slate.com/technology/2...

tinyurl.com/reuxynmc Very excited to see this work I was a small part of published! We analysed two large scale colocalisation datasets: OpenTargets data and an analysis of immune-mediated disease GWAS/immune cell eQTLs seeking to understand the "colocalisation gap". Some highlights:

I am once again begging, praying, weeping for lists of written instructions rather than videos. I do not want to watch your two minute video in the hope of catching the two seconds where you whizz past what goddamn menu the thing is under. Write. It. Down.

Being a PI is an intricate juggling act that requires tough decisions – intellectual, financial, strategic. Yet we are expected to navigate these dangerous waters with very little support. The solo PI model is deeply problematic. My latest blog post #AcademicSky occamstypewriter.org/mindthegap/2...

I am excited to share my first paper, our new preprint: www.biorxiv.org/content/10.6... with @arbelharpak.bsky.social and @docedge.bsky.social. Family GWAS provides direct genetic effect estimates and is increasingly important. But how much can we trust these estimates? (1/15)

Let nobody say there isn't a plan in place

This is a lovely friendly conference for early career researchers. Highly recommended, submit your abstract!

existence of confidence intervals implies existence of diffidence intervals

Now published in CEBP: doi.org/10.1158/1055... In summary: we did not find a significant effect of PCSK9 on BC survival using Mendelian Randomization.

Very important thread about accessing NHS data for scientific progress. We (our processes, not our researchers) need to get better at this.

If you're interested in the history and philosophy of randomization in all its forms I'm co-organising a *FREE* conference in glorious Bristol 2-3rd July wth the legendary Samir Okasha, registration is here www.eventbrite.co.uk/e/randomizat... If you think it looks interesting please advertise

As I process large gwas summary files I am so thankful, yet again, for tabix. So fast.

But it's great for getting more grant funding so you can re-analyze the nurses health study for the umpteenth time, hoping to catch another p < 0.05.

UKRI to phase out funding for hybrid open access. www.researchprofessionalnews.com/rr-news-uk-o...

Great summer school, free, with travel bursaries! Right now is a very good time to specialise in making sure our science is true

🚨 Job Alert in my lab! Clinical PhD in Rare Respiratory Disease Suitable for any resident doctor up to ST8 Birt-Hogg-Dubé models in @thecimr.bsky.social www.cam.ac.uk/jobs/researc...

777 studies, 745 with summary statistics - the @genesandhealth.bsky.social WES study is now in the GWAS Catalog, aiming to improve health outcomes for South Asian populations. Go explore 👇 www.ebi.ac.uk/gwas/publica...

Some genuinely good news!

Completely agree! Also, to my co authors, this is why my first drafts look like they do 🫣

Just discovered ggmagnify hughjonesd.github.io/ggmagnify/re.... love it! But quite probable that I will overuse slightly creating figures for my next talk. You have been warned.

What I most want employers to understand is that writing code and performing meaningful data analysis are not the exact same skillset. #rstats

Brutal.

📢We’re hiring! 3 Research Associates to join Professor Arthur Kaser's lab at #CITIID to investigate FAMIN, a core enzyme we discovered that prevents inflammation and autoimmunity. ➡️https://buff.ly/Gtbb6ss ➡️https://buff.ly/W4cr9xC ➡️https://buff.ly/kDv7VdI Apply by 9 April.

A thought about job adverts. I assume seeking "exceptional" individuals selects for specific character traits (eg self confidence). My goal is to get candidate with best potential, even if they don't yet think of themselves that way. What words do you use to encourage the widest pool of applicants?

glue::as_glue() documentation says result is a vector with S3 class "glue". But is.vector(glue("thing")) returns FALSE Can anyone explain? #rstats conundrum

The UK could do this too. We should.

It is the anniversary of the My Lai massacre today. I'd say that even more than most years, it's important to remember what happened. And the role Hugh Thompson, an active serviceman, played in both stopping and publicising it. Despite enormous military, political and public pressure to stay quiet.

😱🤯 -- Just looked up the cost to go gold open access at Nature Eco Evo: US$12850! That's $21,600 NZD. That's the same cost as a Royal Society Master's Scholarship! This has gone too far. Absolutely bonkers.

Filling in a reference where I am asked to score someone from 1 to 10, where 5 is average. Tempting to include a suggestion they start with 0 to put 5 in the middle. (It's Friday night. I should be less irritable. But they also sent the form with a 107 minutes deadline to submit. Hence, irritable)

🧬 New today! 📄 Higher eQTL power reveals signals that boost GWAS colocalization 🧑‍🤝‍🧑 @mikelove.bsky.social @klmohlke.bsky.social & colleagues

once your email storage is full you should be allowed to graduate from it. no more emails for you. you’ve seen enough emails. you’re free now

Game changer.

#BlueSkyArtShow #Two Cambridge

Join IGES for our next two journal clubs! Register here: www.geneticepi.org?id=255 🗺️ On 2/23, Mateus Gouveia will show how race and ethnicity align with continuous, rather than discrete, genetic variation. 🧮 On 3/6, Diptavo Dutta will introduce joint sparse canonical correlation analysis (jsCCA).

Opinion: When a mere few months’ hiatus in UKRI funding opportunities imperils the futures of those without permanent posts, it only underlines the fragility of UK biomedicine, says a researcher #AcademicSky #Research ow.ly/q32l50Yhv9m

The Blue Journal thanks Eckart De Bie, MD, MPhil, for his contribution to the January issue Inflammation and Obesity Correlate in Pulmonary Hypertension but Associate with Diverging Outcomes @mark-toshner.bsky.social academic.oup.com/ajrccm/artic...

Just checking, it's now ok to flee your homeland, because you're afraid for your safety, and seek refuge in another Country? Glad we've cleared that up. Let's hear no more about immigration and refugees then.

😂

#MorningVibe The only thing stronger than hate is love. ♥️ Bad Bunny Without love, where would we be now? ♥️ The Doobie Brothers Don’t just say it. BE it. 🔊🔊🔊🆙

🧬 International Women & Girls in Science Day 🧪 At VPD-HLRI, we’re proud to support women at every stage of their careers. Meet Jennifer Martin — PhD student, new mum, and haematology data scientist — inspiring the next generation of female scientists. #WomenAndGirlsInScience #WomenInSTEM

I hate commenting/suggesting edits on a paper written in overleaf. I love writing in latex, but Google docs is just so much more intuitive for collaboration. Does anyone know a latex platform that is genuinely good for collaborative writing?

If you care about official statistics this is an opportunity to join the Regulation Committee of the UK Statistics Authority. It meets 5 times a year. Members receive a £3k fee uksa.statisticsauthority.gov.uk/news/vacancy...

Also: shifting scientific funding towards "government priority areas" is a surefire way to kill creativity and innovation. Generating scientific knowledge is not like ordering a takeaway. You can't just tick the 'science' that you want and expect anything useful.

I made a map of 3.4 million Bluesky users - see if you can find yourself! bluesky-map.theo.io I've seen some similar projects, but IMO this seems to better capture some of the fine-grained detail