Now published! Our paper on: (1) Accurate sequencing of sperm at scale (2) Positive selection of spermatogenesis driver mutations across the exome (3) Offspring disease risks from male reproductive aging [1/n] www.nature.com/articles/s41...

Happy to share that this work together with @opentargets.org is now out at Nature Communications.

Scientists have uncovered hidden genetic drivers of conditions like IBD by stimulating immune cells. 🔬 The findings have resulted in a dataset called MacroMap, which offers insight into why some people are vulnerable to certain conditions. sanger.ac.uk/news_item/ac...

KELLYGOAT

🚨New preprint just dropped 🚨 medrxiv.org/content/10.1101/2025.06.24.25330216 The main output from my PhD is finally public and we’re SUPER excited about the findings! If you’re interested in what we learnt about IBD with a massive 700+ sample sc-eQTL dataset of the gut, read on!

An awesome preprint by a superstar PhD student looking at the utility of blood vs tissue in the context of disease!

🚨 SUPER EXCITED to share our new preprint on the mucosal and circulatory immune landscape of Crohn’s disease! 🩸 Blood is commonly used in biomarker discovery and drug development, but how well does it reflect what's actually happening in the gut? 👀 🧵 1/10 🔗 www.medrxiv.org/content/10.1...

Heading to #EMDS24 in 🇦🇹 this week? Come hear about our work on the "inflammatory handbrake" exerted by intestinal monocytes in human IBD and murine colitis through ACOD1. Wednesday, Session 4 1640-55; See you there! www.biorxiv.org/content/10.1...