The #RAREsummit25 agenda is live! Packed with diverse voices, patient-driven insights & bold innovation. www.camraredisease.org/raresummit25... Grab your ticket to join us on 6 Nov to be part of the conversation & on't forget to book your dinner spot! What are you most looking forward to?

We've just welcomed this year's cohort of MPhil students studying the Molecular Mechanism of Human Disease so it's time to start preparing for next year! Applications are now open - details and link to apply here: www.cimr.cam.ac.uk/masters-mole...

Only two more days to go!! This Saturday from 10am to 4pm at Hills Road Sixth Form @thecimr.bsky.social will be joining Big Biology Day. Come along and bring your #family to join in lots of #fun #science activities.

Applications now open for our work experience programme for year 12 students, run with @mrc-mbu.bsky.social & @stcatharines.bsky.social We give students a valuable insight into life as a research scientist and student in Cambridge. Details & application link here: www.cimr.cam.ac.uk/inspiring-sc...

Great to welcome our second cohort of students to our Masters in Molecular Mechanism of Human Disease today. Have a good year everyone!

We're looking forward to the Big Biology Day at Hills Road Sixth Form on Saturday 11th October - who's coming?

*job alert** Wanted - 2 enthusiastic postdocs to join me @thecimr.bsky.social and Emma Rawlins @labrawlins.bsky.social to build complex models and use -omic approaches to understand mechanisms in human lung disease in collaboration with GSK. Contact us for more info! www.jobs.cam.ac.uk/job/52936/

Great new paper highlighting @jenniferepalmer.bsky.social 's PhD work: www.cimr.cam.ac.uk/research-adv...

New JCS snapshot - Cytotoxic T lymphocytes adapt to the loss of Cdc42 @adamrochussen.bsky.social presents the key findings from their recent JCS paper with Claire Ma and Gillian Griffiths @griffithslab.bsky.social. journals.biologists.com/jcs/article/...

🧠 Cambridge scientist reveals how autophagy clears toxic proteins in neurodegeneration in Genomic Press Interview. Dr. Rubinsztein's breakthrough: cellular cleanup fights Huntington's, Parkinson's & Alzheimer's! 134k+ citations 🔬✨ 📄🆓 DOI: doi.org/10.61373/bm0... Source: genomicpress.kglmeridian.com

. @adamrochussen.bsky.social, Claire Ma & Gillian Griffiths @griffithslab.bsky.social find that deletion of Cdc42 in primary T cells triggers transcriptional adaptation, leading to enhanced T cell function. journals.biologists.com/jcs/article/... Article: journals.biologists.com/jcs/article/...

Sometimes, knocking out a gene isn't a good way to figure out the function of that gene ... In our new @jcellsci.bsky.social paper, we report potent transcriptional adaptation by cytotoxic T lymphocytes (CTLs) in response to CRISPR/Cas9-mediated deletion of the important polarity protein CDC42 🧵⬇️

Great news² 🥳 Clinical PhD student Niki Veale has just passed his PhD viva so will become Dr Dr Veale (Dr² Veale) We’ve also learned that he’s secured a Clinical Lectureship so will return to the lab as a post-doc (or is that post-doc-doc?) @thecimr.bsky.social @veale-n.bsky.social

Congratulations Adam!

New preprint alert! Endogenous gene editing of alveolar organoids to investigate mechanisms of epithelial dysfunction in familial ILD. Kudos first author @eimearrutherford.bsky.social and thanks @thecimr.bsky.social @labrawlins.bsky.social @profmarciniak.bsky.social www.biorxiv.org/content/10.1...

Could climate change bring new diseases to the UK? Prof Michael Weekes spoke to @the-independent.com recently www.independent.co.uk/climate-chan...

We had a such a great week with this lovely group of students on @gurdoninstitute.bsky.social ASTP programme- they did some fantastic presentations on Friday! Well done to all of them 👋👋👋

Such a rewarding experience to host these ASTP students and guide them through an exciting weak of science discovery @thecimr.bsky.social I’m glad I could convey the importance of sterile conditions in cell culture 😂😂

We're loving hosting students for the @gurdoninstitute.bsky.social ASTP programme, along with @mrc-mbu.bsky.social . As ever, so impressed with the next generation of scientists!

Rounding up today's flurry of new papers is this one from the Salje lab www.cimr.cam.ac.uk/research-adv...

And another one from the very busy @deanelab.bsky.social - this time PhD work from Alex Nicholson www.cimr.cam.ac.uk/research-adv...

New in from @deanelab.bsky.social www.nature.com/articles/s41...

New insights from the Salje lab into the little-known but common Scrub typhus - a vector-borne human disease caused by the bacterium Orientia tsutsugmushi and spread by mites: www.cimr.cam.ac.uk/research-adv...

Great new paper from the Rubinsztein lab www.cimr.cam.ac.uk/research-adv...

Is the next step of your career at the LMB? Come and find us at the @cambridgebiocampus.bsky.social Campus Jobs and Career Fair this Saturday 21st June at the Cambridge Academy for Science and Technology! More details here: cambridge-biomedical.com/event/cbc-jo...

Join @crukcamthoracic.bsky.social For the launch event of 'NextGen Researchers'. A great opportunity to connect with like-minded early career cancer researchers in Cambridge! 📅 Thursday 10 July, 5-6pm 🍕 Pizza provided 📍@vpd-hlri.bsky.social Register ➡️ www.eventbrite.co.uk/e/nextgen-re...

Very excited to share our second preprint from the lab ‘Dual effect of alpha-synuclein disease variants on condensate formation’ www.biorxiv.org/content/10.1... Great work from Aswathy, Aishwarya, Tianhao and our collaborator Tiago Outeiro. Thanks to @thecimr.bsky.social and @royalsociety.org.

📢 Don’t miss our next Cancer Biology and Medicine talk on Thursday! Early cancer trials Dr Simon Pacey @cuh.nhs.uk Thurs 5 June, 9:30-10:30 TC Lecture Theatre, School of Clinical Medicine All welcome @cambridge-scm.bsky.social

Great new paper from Melissa Gammons' lab working with the @mrclmb.bsky.social

We are delighted too!

Come & work with us! We're looking for a Research Manager who will significantly contribute to the research output & future of CIMR, working with the Director & senior leaders to help maintain & enhance the outstanding research environment Details & application here: www.jobs.cam.ac.uk/job/51260/

Are you, or do you know, a sixth-former interested in biomedical research? We're holding an on-line event in July where you can find out about career paths from researchers at different stages of their career, hear about our research, and watch a demo of an experiment. Details here 👇

📢 One week to go! Don't miss the chance to apply for our Museum Experience Internship at @maacambridge.bsky.social this summer. 🗓️ Applications close at 8am on Thursday 8 May. ➡️ museums.cam.ac.uk/new-internships

Are you (or do you know) a sixth form student interested in the biomedical sciences? We're running an on-line event over three mornings 28th-30th July. Find out more and apply here: www.cimr.cam.ac.uk/reaching-res...

Applications are now open to join our Summer Research Programme! 📍 Live in @corpuscambridge.bsky.social 🔍 Work in the lab 🚀 Start your research journey Deadline: 21 April www.cruk.cam.ac.uk/students/und...

Some fascinating research from @profmarciniak.bsky.social and colleagues

Very excited to be presenting our work on alpha #synuclein phase separation at #CamNeuro2025 today. #Neuroscience #Cambridge #Neurodegeneration @camneuro.bsky.social Research @thecimr.bsky.social @cambridgeuni.bsky.social @royalsociety.org Interesting view on todays lecture Theater..

I'm delighted to be hosting the Cambridge University Endocrinology Society's annual conference this Friday, entitled: 'From Bench to Bedside (and back again)'. We're really fortunate to have such an exciting line up of speakers, integrating across a wide range of career stages and fields.

Some of our researchers joined @campathology.bsky.social as part of @cambridgefestival.bsky.social this weekend to entertain the public with disease-related chat and activities! Lots more festival events to come: www.festival.cam.ac.uk/events

Well done Jessy @jessyzhu-jiayi.bsky.social who gave her #biologists100 flash talk today about her new GCN2 activators @biologists.bsky.social @thecimr.bsky.social

Looking forward to Synuclein #Meeting in sunny #Cambridge. All posters from the lab are in the line up. And I will be presenting our work on VAMP2-mediated #synuclein phase separation on 9th - early morning 😊 See you all soon!! #Science @thecimr.bsky.social @cambridgeuni.bsky.social #Parkinson

What a fantastic day at #CambridgeFestival!! @thecimr.bsky.social contributed again to this years Cambridge Festival at the Biomedical Campus. Thanks to all amazing colleagues from @thecimr.bsky.social, @cambridgeuni.bsky.social making this event run!! More here: www.lautenschlager-lab.com/blog

😊 Very happy to see this out! A real group effort from the Hyslop lab (@thecimr.bsky.social) including brilliant collaborations with @knowleslab.bsky.social, Vendruscolo lab, @michael-e-ward.bsky.social lab, @deriverylab.bsky.social lab, @profmarciniak.bsky.social lab 🎉🎉🎉

We had a great time @cambridgefestival.bsky.social with our friends @mrc-mbu.bsky.social - thanks to everyone who came! Loads more festival events coming up - check out the programme here: www.festival.cam.ac.uk

2025 Alpha synuclein conference will be held in April in Cambridge; details here airdrive.eventsair.com/eventsairwes...

Delighted to share our latest paper on alpha-1-antitrypsin deficiency, in @naturegenet.bsky.social. A fun collaboration between groups of @matthoare20.bsky.social, @profmarciniak.bsky.social, and Peter Campbell. @thecimr.bsky.social ky.social, @sangerinstitute.bsky.social, Early Cancer Institute

Today March 4, is world obesity day. People with obesity are not bad, they’re not morally bereft, they are fighting biology #obesityisnotachoice

We loved hosting the latest cohort of students to our ISAC/M programme over half term, along with @mrc-mbu.bsky.social and St Catharine's College. What a fantastic group of young people! www.cimr.cam.ac.uk/news/inspiri...

Rare Disease Day honours 300 million extraordinary individuals worldwide. Proud of our work in Geoff Woods’ lab @thecimr.bsky.social to help patients with rare sensory disorders, and hugely grateful for their engagement in research that advances knowledge & healthcare systems to benefit us all.

We're having a great half term week with a fantastic group of young scientists who've given up their school holiday to experience life as a research scientist. Run with @mrc-mbu.bsky.social and St Catharine's College, www.cimr.cam.ac.uk/inspiring-sc... aims to widen participation in STEM & medicine