Terence Crawford, 5-division champion, retires undefeated, walks away 42-0 with historic achievements. Read my story (free to all) & sign up for my #boxing newsletter: danrafael.substack.com/p/terence-cr...

Cancer’s been known to knock the body’s stress response out of sync. In mice, the Borniger (@jborniger.bsky.social) lab has found that stimulating key neurons at the right time can restore healthy stress hormone rhythms, bolstering the body’s anti-tumor defenses. www.cshl.edu/day-night-ca...

The co-first authorship order was determined via the best of three rounds in Super Smash Bros.

The toxic crab (Lophozozymus incisus), a rare and very beautiful species found in warm waters the world over, including off the coast of Australia. Toxic crabs can be incredibly dangerous, containing toxins that are similar to those of the pufferfish, called tetrodotoxin and saxitoxin. #crustmas

🎶🐁 #neuroskyence

Rage Against the Machine, Gang Starr and At the Drive In Rakim, De La Soul and MF DOOM Lauryn Hill, Outkast and the Roots McCoy Tyner with Gary Bartz Yule Prog 4-10

Two breakthroughs in one! Two new studies from CSHL molecular biologist Chris Vakoc, published in @natcomms.nature.com and @cp-cellreports.bsky.social, help explain the bizarre behaviors of pancreatic cancers and lung cancers that can change identities. www.cshl.edu/shapeshiftin...

“A long time ago in a galaxy far, far away” was meant to be ironic. The doubling up of ‘far’ is the giveaway. It’s the future given Lucas’ view of the world in 1977.

A little brainteaser I wrote: Writing 'not unlike' is not unlike writing 'like', unlike writing 'unlike', which, unlike writing 'not unlike', is not like writing 'like'. #WritingCommunity #BookSky #WriteSky #WordPlay

As a longtime fan of cool papers in @currentbiology.bsky.social, I am really thrilled to see this out! This study sets the stage for understanding the origins of novel (vocal) behaviors. Big shout out to the main architects of this work @xmikezheng20.bsky.social and @cliffscience.bsky.social

By @warrenellis.ltd.web.brid.gy with art by AJ Brady.

Happy Partially Muscled Skeleton Stands By The Perimeter Fence and Screams for Thirty Seconds Before Vanishing Day to all who celebrate

At CSHL's Uplands Farm, researchers are are cultivating corn, sorghum, and more to test the roles of different genes. Read more to discover CSHL's long history and exciting future in plant biology. www.cshl.edu/uplands-farm...

CSHL Professor David Spector and grad student Disha Aggarwal examined tissue samples from a 59-year-old woman diagnosed with stage 1 triple-negative breast cancer. Their findings could help inform clinical trials of a drug targeting the long non-coding RNA MALAT1. www.cshl.edu/breast-cance...

A new study from the Furukawa lab (@lab-furukawa.bsky.social) identifies the neurological ‘doorstops’ that keep the brain’s NMDA receptors fully or partially open. The findings could have implications for treating neurodegenerative conditions like #Alzheimers disease. www.cshl.edu/a-doorstop-f...

Synesthesia, shipwrecks, and African elephant all await you in the smelliverse! Get a guided tour from CSHL Professor Alexei Koulakov in our Cocktails & Chromosomes video. @alexkoulakov.bsky.social #NeuroSkyence youtu.be/b5i0gUz3O1I?...

Related and more painful

The mystery of medical diagnosis!

Did you know that breasts have branches? Disturbances to this tree of life can have implications for breast cancer risk. Now, three grad students in CSHL's @caoresco.bsky.social lab have developed a computer model for measuring such changes. #BreastCancerAwareness www.cshl.edu/the-magnetic...

I wrote Jane Goodall's obit for Smithsonian & throughout my reporting, I learned more about what an incredible scientific trailblazer she was. She opened doors for generations of women had such a profound impact on so many people across the world. www.smithsonianmag.com/science-natu...

I have eaten Mexican food every day for the past six days and every meal for the last three. It doesn’t feel the least bit strange. It just feels like living right. And no, I am not currently in Mexico

Plant stem cells shape how crops grow—yet their key regulators remain hidden. CSHL researchers have now mapped these rare cells in maize & Arabidopsis, uncovering new genes tied to growth & productivity. This knowledge could help breed more resilient, high-yield crops. www.cshl.edu/youve-never-...

When Bud Crawford did this to Spence the world should’ve taken more notice. Spence one of the best in generations. That’s how good Crawford is. Canelo is outmatched

Two flagship papers from the International Brain Laboratory, now out in ‪@Nature.com‬: 🧠 Brain-wide map of neural activity during complex behaviour: doi.org/10.1038/s41586-025-09235-0 🧠 Brain-wide representations of prior information in mouse decision-making: doi.org/10.1038/s41586-025-09226-1 +

Last month, the Genome Engineering: CRISPR Frontiers meeting at CSHL brought together the field’s top minds to share unpublished breakthroughs & push the frontier forward. www.cshl.edu/videos/enter...

Invasive microscopic foraminifers hitchhiked to the Long Island Sound more than a century ago, new #ScienceAdvances research finds. https://scim.ag/464QkLF

Call it one of the world’s smallest cat videos. To demonstrate an advance that could one day help build a type of quantum computer, researchers have made a cartoon of Schrödinger’s cat using hundreds of individual atoms, rearranged as often as once every 60 milliseconds. https://scim.ag/4mIDfhL

There’s been a Benz parked on on a lawn on the side of Sunrise Highway in Wantagh with a cardboard sign in the rear windshield reading “Defund Family Court.” It’s been there all week, meaning Nassau cops have chosen to let it sit there. I imagine there’s a good story in this for anyone so inclined.

Met Kool Herc today at a screening of a documentary about Antarctica. Clearly I’m exactly where I need to be in time and space.

Earth is so dope

“In bone marrow alone ~500 million cells are born every min” says Bruce Stillman. Each must duplicate 2+ meters of DNA to avoid errors that can cause cancer & autism. See more from Stillman, @crick.ac.uk’s John Diffley & @uuhsresearch.bsky.social's @jiwasa.bsky.social www.cshl.edu/licensed-to-...

#MusicChallenge 15 years of Cut Chemist "Sound of the Police." 1st listen to this international one turntable/loop pedal/mixer mix. Deep dive into original vinyl from around the world, with some hip-hop bits. The loop pedal has a mostly hypnotic effect. Best to start at the beginning!

Our latest work featured in The Scientist! Sneha Khedkar Did a great job in summarizing the work accessibly while retaining some of the fine details. Happy reading! www.the-scientist.com/batman-signa...

Kool Keith didn't care for the Native Tongues era: open.substack.com/pub/unkut/p/...

Researchers at the renowned Cold Spring Harbor Laboratory have documented 35,000 tomato branches over three years.

Consider the example of a chemical spill.

Heard this for the first time on WKCR tonight. I really need to get deeper into Material. I can’t be the first to say Trent Rezor bit this, can I? Anyway, RIP Sly Stone youtu.be/V7qkhfNmL5w?...

President & CEO Bruce Stillman reflects on decades of scientific progress & issues a call to action. As public funding declines & immigration policies tighten, the future of innovation is at risk. The U.S. must continue investing in science & the people behind it. www.cshl.edu/presidents-e...

David McCandlish (@davidmccandlish.bsky.social) & Justin Kinney (@jbkinney.bsky.social) developed a new mathematical approach to improve how we model DNA, RNA, & proteins, making it easier to interpret results & apply them in real-world settings. www.cshl.edu/in-natures-m... ‬

From reading The Hallmarks of Cancer in Spain to sharing pancakes with its author at CSHL—Lucía Téllez Pérez’s journey in cancer research came full circle. Read her inspiring story below. #CancerResearch #CSHL #ScienceLife

Joshua-Klitschko was one of the best fight weeks I ever covered and one of the best fights, 8 years ago today. Check out the video on the anniversary of the bout for my memories of this epic event and subscribe to the YouTube channel! www.youtube.com/watch?v=fqS5...

In a new Science study, researchers describe a neural circuit underlying cachexia-related apathy in a mouse model of cancer. Learn more: scim.ag/4iIQFbq #SciencePerspective

“Life exists at the interface of genetically encoded processes and environmentally driven realities. So too should the biomedical enterprise that studies it.”

Pancreatic cancer is projected to become the second-deadliest cancer by 2030, but new research from CSHL may offer a path forward. Professor David Tuveson & Research Investigator Claudia Tonelli have discovered a way to intercept pancreatic cancer before it fully forms.

I will be selling records in the back-right corner of a giant room this Sunday

🫨 www.cshl.edu/quiz/a-perce...