I run my lab in my home for about 20yrs now. You absolutely can and kits from Carolina dot com, Edvotek, MiniPCR, etc can help reduce overhead. Amazon and ebay for labware. Sequencing via plasmidsaurus is cheap now and can do zero prep so just need clean sample of bug

12 years in the making - we are finally scaling up our “universal diagnostics” platform. m.youtube.com/watch?v=gbeg... Read about the global program here: news.stanford.edu/stories/2026... If you are passionate about bringing cutting edge tools to work for “everyone” - reach out and engage.

Drosophila Transglutaminase preserves the integrity of muscle attachments with and without mechanical strain #Drosophila

And the new NCI Director moves to piss away his scientific credibility. First, killing cancer cells is a very low bar; many compounds kill cancer cells and are not the least bit useful for treating cancer. 1/2

#Halifax regional council meets today starting at 10am. There are also budget committee meetings tomorrow, Thursday, and possibly Friday. It's a busy week! I may pop down to City Hall later but here's a piece I wrote yesterday about what's on the agenda. www.halifaxexaminer.ca/government/c...

Let's learn about the coquí frog 🐸 (Eleutherodactylus coqui), native to Puerto Rico where it is a beloved national symbol. I want to focus on their call: two tones described as co- and -quí. (SOUND ON) Take a listen 👂 & see if you spot the pattern. Then I'll tell you something amazing about it.

How many examples to we need--its time to rise up the same way as the nation did after three murders by the ICE thugs--release all children and their parents NOW

Our #preprint list is up on FocalPlane. This list focusses on the latest tools in bioimage analysis. Let us know if you have any recommendations to add to our list. focalplane.biologists.com/2026/02/06/m...

Only recently started watching an ICE report map (rather than just happening upon posts) and, like, I knew it was bad but I didn't realize how bad. If you're in the US and don't think there are abductions happening near you, you're just not correct.

A paper in Nature describes a collection of soft‑bodied fossils discovered in a quarry in China, dating to around 512 million years ago. The Huayuan biota contains 153 animal species from 16 major groups, of which 59% are previously undiscovered species. go.nature.com/49KUOdw #Paleosky 🧪

Isadonna Tengganu and Ke Hu develop transfection and ExM protocols for Chromera velia, enabling direct comparisons with its parasitic apicomplexan relative, Toxoplasma gondi. journals.biologists.com/jcs/article/...

the real story is they lied so they could terrorize Latin American immigrants.

The Dragonhunter (Hagenius brevistylus), one of North America's largest dragonflies, specializes in hunting other dragonflies. a.co/d/gAgXe4q?ta... 🧪🌿🌎🐡 #wildlife #medart #scicomm #sciviz #wildlifeart #illustration #scientificillustration #natureart #visualscicomm #sciviz #scicomm #dragonflies #odos

Memorializing the contributions of Dr Paul Kulesa to neural crest cell biology & imaging, a generous colleague & mentor, devoted husband and father. @devdynamics.bsky.social @anatomyorg.bsky.social

🧨 Check out this peeps🧨 I am very happy with the outcome of this thought baby! @neurogut.bsky.social @michaelrera.bsky.social and Mael Lemoine (yes, a philosopher) twisted our brains over preparing this conceptual review! We give you the "Enterarchon" Enjoy it! www.sciencedirect.com/science/arti...

Dynamic actin waves in a zebrafish embryo. Credit to @aaandmoore.bsky.social & Dvir Gur. #ZebrafishZunday 🧪

I can't overrecommend this incredible paper about water skaters (genus Halobates). No one knows how they evolved. No one knows what they eat. They are superhydrophobic, which means water LITERALLY CANNOT WET THEM. Perhaps we should call them anti-water skaters? 🌊🧪 journals.plos.org/plosbiology/...

The number of children in ICE detention on a given day has skyrocketed, jumping more than sixfold since the start of the second Trump administration. We analyzed data obtained by the Deportation Data Project and found that ICE held around 170 children on an average day under Trump.

Make your gene knockouts more efficient with multiplexed Cas12a sgRNAs. Our new paper is out now, with tools available from @addgene.bsky.social , www.plasmids.eu and @vdrc-flies.bsky.social. www.nature.com/articles/s41... #CRISPR #geneediting #Drosophila 🧪🧬✂️🔬🪰 Summary 🧵 below.

If you aren't familiar with what DARVO is, get familiar with it. "Deny, Attack, Reverse Victim and Offender." The govt is relying on DARVO as a tactic on a national scale, and it is also increasingly a conservative tactic to attack outspoken critics of their ideas, theories, & renderings of history.

Calling all JEB ECRs! It's that time again! The deadline for the next JEB Travelling Fellowship applications is 6 February, so if you've got a burning desire to travel to another lab to answer an extraordinary question get your application ready now! www.biologists.com/grants/trave...

I cannot tell you how much doubt was consistently directed at the Gaza Health Ministry’s casualty numbers and how much pressure was put on news organizations to couch those numbers as unreliable. Biden himself said they were fabricated! www.haaretz.com/israel-news/...

This is very thoughtful. Is the U.S. on a slow march to civil war? Morning File by @philmoscovitch.bsky.social

Jane Richardson was born #OTD in 1941 + Developed the Richardson (ribbon) diagram to represent proteins' 3D structure (becoming a standard representation for protein structures) + MacArthur Fellow, 1985 + Elected, Nat'l Academy of Sciences, 1991 + President, Biophysical Society, 2012 #WomenInSTEM

Our CytoTape work is published today in Nature @nature.com! CytoTape is a genetically encoded, flexible, intracellular protein tape recorder for spatiotemporally scalable and multiplexed recording of cellular activities continuously across weeks in vitro and in vivo. www.nature.com/articles/s41...

SAVE THE DATE: The Atlantic Canada Regional Cell & Developmental Biology Symposium will be held on June 26th, 2026 at Mount Saint Vincent University in Halifax, Nova Scotia, Canada. @anatomyorg.bsky.social @brchfx.bsky.social #devbio #DevBio 🧪

Panic is over, the clones will be available at the transgeome site once the website is updated. The flyfos project is such a useful resource that I 😱about not having access to it anymore.

#Drosophil. Does anyone know who hosts the flyfos GFP tagged library now? We need some constructs but I cant find where they are. doi.org/10.7554/eLif...

Why are some Drosophila flies paralyzed at cold temperatures, and others aren't? 👇

Have a look at our latest preprint, "Nuclear plasticity regulates macrophage phagocytic capacity in vivo". #apoptoticbodies #efferocytosis #nucleus #Drosophila #macrophages #mechanoresponse #InVivo #LiveImaging doi.org/10.64898/202...

Latest from the lab. MS previously preprinted (see below) and finally published in print @dev-journal.bsky.social journals.biologists.com/dev/article/... Review process via @reviewcommons.org and @dev-journal.bsky.social 1/3

Under a zero tolerance policy, the first Trump administration separated immigrant children from their families at the U.S.-Mexico border. Data suggests separations are now happening all over the country, often after little more than a traffic stop. (Published Nov. 2025)

As 2025 comes to a close, my university (Dalhousie U in Halifax, Canada) is recruiting faculty, including outstanding early career researchers, and Canada Research Chairs. Applications are due January 19 2026 (was just notified today!). Please repost.

Talin didn’t evolve for integrins... integrins evolved for talin 🤯 pN force coupling via talin is ancient, conserved from amoebae to humans; signaling came later. Read this amazing paper here 👇🏽 www.nature.com/articles/s41...

We have recently updated FlyCyc biocyc.org/DMEL/organis..., the pathway-genome database representing Drosophila metabolism, to include enzymatic complexes as well as further improvements to enzyme annotations. #FlyCyc is now classed as a ‘Tier 1 Highly Curated Organism Database’.

The homeodomain-interacting protein kinase Hipk promotes apoptosis by stabilizing the active form of Dronc #Drosophila

Who wants to come to a bug conference on the east coast? Save the date for the Acadian Entomological Society's 2026 meeting, June 18-20, to be held right here in Antigonish @stfx-university.bsky.social @davidawde.bsky.social

An energy-based model of protein conformational space can be used to predict structure from sequence, sample from the conformational landscape, rank structures, and predict mutation effects. @sokrypton.org www.biorxiv.org/content/10.6...

Aaand... my first cover!! RpS6 phosphorylation (magenta) in a Udd (ribosome biogenesis factor) mutant ovary 🔬

Exciting new #Zebrafish research from the #WeinsteinLab, led by Jong Park! “Specialized gas-exchange endothelium of the zebrafish gill” — www.biorxiv.org/content/10.6... Amazing to see red blood cells moving through the gills! Don’t forget to check out the supplemental movies ;-)

From January 1st 2026, the CNRS will cut access to one of the largest commercial bibliometric databases, Clarivate Analytics' Web of Science, along with the Core Collection and Journal Citation Reports.

ROS heal the cricket leg This Research Highlight showcases the work from Misa Okumura-Hirono, Tetsuya Bando and colleagues journals.biologists.com/dev/article/...

thanks, @coastalseaside.bsky.social for the delicious w[1118] #Drosophila cookie!

dFlpTag, a RMCE-based tool for simultaneous endogenous protein tagging and cell labeling in Drosophila #Drosophila

Reliable Identification of Homodimers Using AlphaFold https://www.biorxiv.org/content/10.1101/2025.11.27.691011v1

Daniel Smith, Sanford Bernstein and colleagues @sdsuresearch.bsky.social uncover the distinct impacts of human co-chaperone UNC45 paralogs on Drosophila muscle development and function. journals.biologists.com/jcs/article/...

Just gonna put this here for now www.science.org/doi/10.1126/... bsky.app/profile/jlst...

Thrilled to share our new paper! With @tomtom-auer.bsky.social team, we asked how #evolution reshapes what animals #eat to match their ecological niches. Using pan-neuronal Ca2+ imaging, we show that the changes are in how the brain processes #taste. Link @nature.com: www.nature.com/articles/s41...

Mameli, Samantsidis, Viswanatha, Kwon, Hall, Butnaru, Hu., Y., Mohr, Perrimon and Smith (2025) A genome-wide CRISPR screen in Anopheles mosquito cells identifies fitness and immune cell function-related genes. 16(1):10323. doi: 10.1038/s41467-025-65304-y. PMID: 41285753

An open webinar on our reproducibility project 'WHAT 400 DROSOPHILA PAPERS Teach Us about Doing Better Science' on December 9th 2PM EEST time (1PM Swiss time). Registration below