How do neurons deal with fitting large regulatory proteins into small spaces to control plasticity and memory? By generating micropeptides via local translation of circRNAs, of course! Here’s to shedding new light on the ‘dark’ proteome in the brain. www.biorxiv.org/cgi/content/...

Ever wondered how robust cellular identity is to external perturbations? Here we disrupt cellular environmnent in vivo and in vitro, and find cell population specific sensitivities. Environment sculpts development yes, but not all cells are made of the same wood. www.science.org/doi/10.1126/...

A rather 'unique' paper from our lab is online in @cp-cellreports.bsky.social now. Unique in the sense that I don't think anyone else will be rushing to optotag cortical interneurons in the early postnatal brain... because it is nigh on impossible! www.sciencedirect.com/science/arti...

The Yang and Phillips labs have an exciting GW4 MRC BioMed DTP PhD project on beta-cell regeneration & designing new proteins with AI tools to control neural signals. Come join us at LSI-Exeter! gw4biomed.ac.uk/regenerating... @proteinmotion.bsky.social @lsiexeter.bsky.social #zebrafish #islet

It was a pleasure writing this Perspective of our work. If you are interested in learning more about activity-dependent regulation of cortical cell numbers, do have a read. tinyurl.com/4ede4jyb

Hello #Drosophila & #insect people! I am searching for libraries of ORF/RNA from Tribolium castaneum and Bombyx mori for cloning cDNA/proteins (or insects with unusual body plans). Is there an existing resource centre where I can find them, please? Thanks very much in advance for your help!

Please share! PhD projects available through @gw4biomeddtp.bsky.social Please get in touch if you are interested in studying chromatin biology in stem cell models gw4biomed.ac.uk/architects-o... gw4biomed.ac.uk/risk-vs-prot... gw4biomed.ac.uk/rna-dependen... gw4biomed.ac.uk/investigatin...

We are recruiting an enthusiastic engineer to work on the core project of our lab: identifying Hox protein-RNA networks in Drosophila @igmm-montpel.bsky.social Interested in BioID, UV-RIP and muscle development? Apply: emploi.cnrs.fr/Offres/CDD/U... Please share! #jobOffer #RNA #hox #Drosophila

Extremely excited to share the outcome of a fantastic collaboration with @erinduffyphd.bsky.social revealing how experiences reshape hippocamapl chromatin and gene expression. Check out our searchable gene database and look up your favorite gene 🧬 www.nature.com/articles/s41...

French only: article vulgarisé de nos premiers travaux d'équipe @igmm-montpel.bsky.social @wxiang007c.bsky.social #RNA #Hox #muscle Merci pour votre soutien a notre recherche fondamentale 🙏 @afm-telethon.bsky.social @agencerecherche.bsky.social

New pre-print on sex differences in the choroid plexus- the 🧠's fluid secretion organ. Important differences in secretory signaling & immune compartments that can impact the 🧠 in health & disease. ‪@karol-kaiser.bsky.social‬@violesilvar.bsky.social‬ Luca von Allmen. 🧪 www.biorxiv.org/content/10.1...

Latest paper elifesciences.org/articles/107... closes an important cycle in our efforts to study regeneration: week-long recordings allow us to observe the behaviour of cells during the entire course of regeneration in a crustacean leg – bright objects in movie are fluorescent nuclei of cells. 1/6

🚨New Review! We explore how thalamocortical circuits wire up by sensory modality — from genes to spontaneous activity and plasticity. @NatureReviewsNeuroscience @glb-lab.bsky.social @neuroalc.bsky.social 🔗https://doi.org/10.1038/s41583-025-00945-y

🧠 Opportunity for a post-doctoral position on human neurobiology, funded by the @erc.europa.eu! 🧫You want to use human pluripotent stem cell based models to understand the evolution of human cerebellar neurons and disorders, this position is for you! 🔗Apply here: emploi.cnrs.fr/Offres/CDD/U...

📢 We are recruiting! Several projects are available and can be tailored to the candidate's profile. Most include confocal imaging/spatial OMICs technologies. Please share and RT 🙏

How do epigenetic modifications contribute to human #neocortex #development? Excited to see our work out in #Neuron. We applied Epi-CyTOF and identified a novel role for PRC2 in regulating #ECM. @crtd-tud.bsky.social @cp-neuron.bsky.social www.sciencedirect.com/science/arti... A thread below 👇

Sharing our latest study on mosaic focal epilepsy. Huge thanks to @mayatalukdar.bsky.social Edward Stronge, Sattar Khoshkhoo, Chris Walsh, all the co-authors, the patients and their families!👇https://www.pnas.org/doi/10.1073/pnas.2509622122#bibliography

And check out the comics version of the paper by @brainotopia.bsky.social 🤩🏆

Fantastic to see the final version out @cellcellpress.bsky.social - it was a real pleasure to contribute to this beautiful work led by the very talented Monika Moissidis during her PhD in @marinlab.bsky.social! Check it out: www.cell.com/cell/fulltex...

The paper is out in journal format at EJN! We thank the reviewers for their insightful comments, and how they shaped the final form of this story. Check it out here: onlinelibrary.wiley.com/doi/10.1111/... As usual, it's open access! We're getting the data ready for sharing very soon 👀🧠🧪

🎉 Thrilled to share our new paper in @narjournal.bsky.social! We uncover how the Hox TF Ultrabithorax controls alternative splicing to shape muscle patterning and homeotic identity 🧬 @igmm-montpel.bsky.social 🔗 doi.org/10.1093/nar/...

Introducing AuthentiSci 🧑‍🔬 We connect scientists with the public through expert reviews of online science claims. 🔬 ORCID-verified experts 💻 Browser extension 🌐 All reviews on authentisci.com Science you can trust. Become part of it!

🧠 I am happy to organise on September 29th 2025, with @sophiechauvet.bsky.social, a Symposium "Linking neural development, human disease and evolution" in the Hexagone, Luminy, Marseille. More detailed for the schedule and registration below!

In the midst of (*waves hands*), our lab received our first NOA from NIMH, as well as our first major private foundation funding. Of course, given everything, hiring at UVA currently is...challenging, to quote our admins, but the first position for our lab is up!

New paper in @oxfordacademic.bsky.social Schizophrenia Bulletin exploring the effects of Setd1a happloinsufficiency on DNA methylation in the frontal cortex. Strong effects on the regulation of ribosomal genes with implications for understanding the genetics of schizophrenia. doi.org/10.1093/schb...

@scheiffelelab.bsky.social and I discussed the unique properties of synapses onto parvalbumin interneurons, the current knowledge & future aspects of the molecular mechanisms regulating these synaptic inputs: www.sciencedirect.com/science/arti...

Check out our new review with @takashi-namba.bsky.social featured on the cover of Trends in Neurosciences 👇

Our study on the impact of altered serotonin (5-HT) signalling on the developing sensory cortex is now live at Nature Comms. We use longitudinal in vivo imaging of 5-HT and neural activity to show that this neuromodulator is buffered in early life to promote bottom-up instruction of sensory areas.

Still openings, check it out!

Got a big showing of talented University of Exeter scientists with talks and posters at ESHG25 in Milan. Come along and find out more! @hls.exeter.ac.uk @exeter.ac.uk #ESHG25 @jamesfasham.bsky.social @jingzhan.bsky.social @ambermluckett.bsky.social @chundru.bsky.social @harrygreentkd.bsky.social

I am looking for a postdoc with an immunology background interested in joining a Yale neuroscience lab to study how the brain controls immunity. At Yale, we have a wonderful interdisciplinary & collaborative #neuroimmune community. Please reach out or share with anyone who might be interested!

Here is the collective effort of 12 labs, lead by my own at the Broad to target the range of cortical interneuron subtypes! These tools should be a game changer for all of you using NHP and other less genetically amenable species! Have at it! urldefense.proofpoint.com/v2/url?u=htt...

Glad to see our new paper finally out! We show how the GPR158 receptor controls synapse maturation and function by silencing an intrinsic inhibitory mechanism. authors.elsevier.com/a/1l7HS5Sx5g... Work from Ben Verpoort and colleagues, with special thanks to our collaborators.

✨We are excited to announce that nominations for the WiNUK Awards 2025 are officially open✨ Nominate someone who’s inspired you in neuroscience, whether they have led bold research, supported you as a mentor, or helped build a more inclusive space, this is your chance to celebrate them! 🧑‍🔬👩‍🔬👨‍🔬 (1/2)

Interested in understanding how neural-pancreas interplay contributes to blood sugar control? We have an exciting PhD project to study galanin regulation of pancreatic #islet hormone secretion in live #zebrafish www.exeter.ac.uk/research/ins...

Latest publication from the lab just out in @dev-journal.bsky.social. Find out what happens to the cerebral cortex when depleted from Cajal-Retzius cells... doi.org/10.1242/dev.... Congrats to all authors, and special thanks to Vicente Elorriaga, Benoit Bouloudi and Nathalie Spassky

Why does the forebrain expand dramatically while other neural regions grow less? Our new publication reveals progenitor metabolism critically shapes region-specific brain growth. Thread below. authors.elsevier.com/a/1k-udL7PXu...

Happening tomorrow! If you’re in Lyon and interested in stem cell heterogeneity and fate choice, pass by @ensdelyon.bsky.social (salle Condorcet) for @zenlabpasteur.bsky.social’s treat talk!

Very pleased with my new @womeninneurouk.bsky.social lanyard badge 👩‍🔬

10/10 Here’s the paper @nature.com if you want to dig in www.nature.com/articles/s41... That’s it. Thanks for sharing! @devneuro.bsky.social @mrc-cndd.bsky.social @kingsioppn.bsky.social @kingscollegelondon.bsky.social @erc.europa.eu

Great to see this out! It was brilliant collaborating with @martijnselten.bsky.social on this work - have a read!

New Preprint out ! The proteasome maturation factor POMP moonlights as a stress-induced transcriptional regulator www.biorxiv.org/content/10.1... Lead by: @sgiando.bsky.social with: @muellermara.bsky.social , @erin-schuman.bsky.social , @marcvoo.bsky.social and many more Short thread below 🧵1/4

I will soon start recruiting for a Wellcome-funded postdoc position! I’ll be at the #BNA2025 meeting next week. If you like cortical development, wiring, and post-transcriptional regulation, do get in touch and we can have a chat in Liverpool! 😀

My lab @kinshiplab.bsky.social is recruiting a postdoc 🚨 with Sept start date Preference for in-vivo ephys / circuits experience / interest in applying quantitative methods to natural social behaviour. Funding & visa fees for 1-yr with possible extension. Send me your CV & visit kinshiplab.org

Job alert 🚨 We are hiring a research assistant! This 7-year position available @exeter.ac.uk from Sept 2025 will involve keeping the lab running as well as contributing to our research activities on brain development. Full details tinyurl.com/23nyds34. Please spread the word!

🍁🚨 WE'RE HIRING!🚨🍁 Our baby lab at the University of Toronto is expanding, many many thanks to funding from #CIHR and @hfspo.bsky.social. We are in search of a technician, postdoc, and PhD students! Further details on our website (sawhlab.netlify.app/people/), please share!

So happy to share the second manuscript of the #QuattrocoloLab. This was a side project of a fantastic PhD student, Kristian Moan, that saw something cool in his data and presented it in our annual lab retreat in 2024. Now the whole story sees the light of day. 1/3

Check out our new preprint! Microglia in different layers of the developing retina express distinct gene profiles - implications for how microglia influence development not just in the retina but throughout the CNS.

New preprint ✍️🚨 ✨Ontogeny of tactile, vocal and kinship dynamics in rat pup huddling -Huddle dynamics develop w/o kinship selectivity -Vocal/internal-state quiets w/ huddling & kin/ touch in yng pups tinyurl.com/y7vhkwjc 👏 @flor-bela.bsky.social @hughtakemoto.bsky.social @kinshiplab.bsky.social

Postdoc opportunity in the heart of Europe! Check out the flyer below. Join our team on an international project with Anthony Holtmaat exploring synaptic plasticity and specificity in cortical and thalamocortical circuits.