Our new preprint is now available on medRxiv! 🎉 Genetic association of T1D stratified by HLA DR3 and DR4 status reveals heterogeneity in pathways of progression to T1D 🔗 tinyurl.com/3fr2kcny A huge thank you to all involved!🧬 #type1diabetes #genetics #type1diabetesresearch #preprint

Interesting finding from @ambermluckett.bsky.social - the non-HLA GWAS of HLA DR3+ and DR4+ type 1 diabetes are surprisingly different (coheritability is only 0.68). Some evidence of less adaptive (CD4) and more innate (mast cell) enrichment in DR3 genetics. #eshg2025

Got a big showing of talented University of Exeter scientists with talks and posters at ESHG25 in Milan. Come along and find out more! @hls.exeter.ac.uk @exeter.ac.uk #ESHG25 @jamesfasham.bsky.social @jingzhan.bsky.social @ambermluckett.bsky.social @chundru.bsky.social @harrygreentkd.bsky.social

Our new paper updating GRS2 with a new tool to easily generate standardised T1DGRS 🧬 Thanks to Seth Sharp, @annagloyn.bsky.social, Richard Oram and @mnweedon.bsky.social for a great collaboration! tinyurl.com/4bsaz9hx