If you work on quantitative cancer genomics, please consider submitting an abstract for our next "Cancer Population Genetics Club" #CANPOP meeting hosted @icr.ac.uk on 15 June 2026. CANPOP is free to attend. Registration & abstract submission here: docs.google.com/forms/d/e/1F...

Our new review on NHEJ just came out on G&D genesdev.cshlp.org/cgi/content/... Highlight the 5 phases, and importantly, the 5 protein bridges that bring the 2 DNA ends together for NHEJ. Thank Dr. Geunil Yi, for generating the illustration for all structural models.

Excited for this film showcasing the important work my lab @mcclellandlab.bsky.social and other labs do at @qmbci.bsky.social . Attacking cancer from all angles with 1st class research by some amazing colleagues

Drs Without Borders refused to hand over staffing lists to Israel because they have habit of targeted murder of medical staff: Israel then bans the medical charity from Gaza. Keep that in mind next time you interact with Israeli institutions www.bbc.co.uk/news/article...

Are you fascinated by cancer biology and also ❤️ 💻 ? Feel like this ->😻<- at the thought of exploring oodles of cancer genomes, single cells and spatial multiomics data? Then our core Data Science Team at @icr.ac.uk might be the place for you. Vacancy here: jobs.icr.ac.uk/vacancies/14...

A major output of the 4D Nucleome project appeared today. This is the joint effort of many scientists working together and (publicly) sharing data and results for several years. We hope this is of interest to many genome biologists! www.nature.com/articles/s41...

Deadline is very soon (12pm November 5th) so get those applications in for a PhD position at Barts Cancer Institute working on radiotherapy resistance , copy number alterations and chromosomal instability !

It’s time for academics and academic institutions to do the right thing www.soas.ac.uk/about/news/s...

Two back-to-back stories on mitosis led by my incredible postdoc @krunovuk.bsky.social at @institutrb.bsky.social, in which we challenge the gliding model of CENP-E-driven chromosome congression! Today in @natcomms.nature.com doi.org/10.1038/s414... doi.org/10.1038/s414...

A follow-up PhD project is now available: www.findaphd.com/phds/project...

Are you a future black leader in cancer? Come join @mirazrahman.bsky.social and my labs @qmbci.bsky.social @kingscollegelondon.bsky.social to work on turning defective cell cycle checkpoints into innovative cancer therapies! Get in touch for more details www.colcc.ac.uk/2026-blic-ph...

Apply to join our lab for a very cool PhD project studying radiation therapy, chromosomal instability, DNA repair and cancer evolution!

Ultimate dream - scientific work leading to major impact on people’s lives, the researchers and Drs involved must be over the moon to treat such a difficult and horrendous disease www.bbc.co.uk/news/article...

We’re excited to share that, after receiving many requests each year from the research community for Oligopaint DNA & RNA FISH probes, we’re piloting a service to design & prepare probes for labs. Please share with colleagues who may benefit! ericjoycelab.com/oligopaint-f...

@mcclellandlab.bsky.social hosted Prof Raksawan Deenonpoe from Thailand so she could collaborate with @mollyguscott.bsky.social & I to look for evidence of chromosomal instability in cholangiocarcinoma. Our work is now published in Journal of Pathology.

About time academics showed some moral fibre www.uu.nl/en/news/utre...

Ever more depraved , like real world Squid Games, they should be relegated to pariah status www.bbc.co.uk/news/article...

New preprint! We solve a mystery you didn't know existed. Mitotic cells lack new transcription but require ongoing translation. Interphase mRNA half life is only 2-4 hrs. So how do cells arrest in mitosis for hours without depleting their transcriptomes? www.biorxiv.org/content/10.1...

We're very proud that our recent PhD graduate (and now postdoc) Rosie Wilkins' study on RNase H2 overexpression in human cells has been published in Oncogene. www.nature.com/articles/s41...

It’s starting 😞 12 children, 21 adults starved to death by Israel. www.bbc.co.uk/news/article...

Great talk by @susanagodinho.bsky.social at London Cell Club today

Two years ago, being accused of bombing a hospital was met with horror and denials. Now, bombing children is met with a shrug www.bbc.co.uk/news/article...

Interested in population genetics of cancer? If so, have a look at our manuscript accepted by @genetics-gsa.bsky.social, in which we provide a theoretical assessment of the genetic makeup of cancers before and after treatment!

We have a new study out - Distinct functions of PAXX and MRI during chromosomal end joining: iScience www.cell.com/iscience/ful...

Delighted to share that the results of my main postdoc project are now published in @nature.com 🔗 doi.org/10.1038/s415...

Hi all, my team institut-curie.org/team/fachine... @institutcurie.bsky.social is looking for a Bioinformatician. You can find more details about the position here: euraxess.ec.europa.eu/jobs/344508 Is anyone looking for a job in the lovely Paris?

📰 New research shows women of African and South Asian ancestry tend to develop and die of breast cancer at a younger age. 🎥 Prof Claude Chelala at BCI @qmul.ac.uk discusses why we must rethink screening and research to ensure no one is left behind as cancer care advances. 🧪 #medsky #oncosky

If you were shocked by my film on Israeli settlers in the West Bank, you haven’t been paying attention | Louis Theroux

Opinion from the FT's Editorial Board: 'The US and European countries that tout Israel as an ally that shares their values have issued barely a word of condemnation. They should be ashamed of their silence, and stop enabling Netanyahu to act with impunity.' www.ft.com/content/f5fd...

Can we use the power of evolution to improve ovarian cancer treatment? Our latest paper says yes! Online now at Cancer Research. Thanks to @trevorgraham.bsky.social coauthors and @cancerresearchuk.org for funding.

this week 20 years ago, Nature published two seminal papers showing for the first time that BRCA-mutant cells were selectively sensitive to PARP inhibitors, paving the way for clinical trials and approval of PARP inhibitors for patients with BRCA-mutant ovarian and breast cancers, and beyond.

📣 Online now! Our study shows how recurrent focal deletions constitute a mechanism by which cancer cells can dampen toxicity due to gene amplification. www.cell.com/cell-genomic... 🧵👇:

Fifteen ambulance staff slaughtered and then hidden in mass grave by Israeli army. www.bbc.co.uk/news/article...

1/Happy to share a new paper reporting a metabolic approach to radiosensitization in lung cancer, from Rachel Chiang, Faith Zhang and colleagues at UT Southwestern Radiation Oncology and @cri-utsw.bsky.social www.science.org/doi/10.1126/...

BREAKING: Yuval Abraham, co-director of Oscar-winning documentary "No Other Land," says Israeli settlers beat his co-director Hamdan Ballal, injuring his head and stomach — and then Israeli soldiers invaded the ambulance he was in and seized him. Ballal's whereabouts are now unknown.

Yesterday David Lammy was unequivocal that Israel is breaking international law. Today No 10 contradicts that and says it is merely “at risk of breaching” the law. It is an extraordinary position to put the Foreign Secretary in - who will now have to say why he was wrong, or why No 10 is wrong.

Nearly 100 Palestinians killed in West Bank by Israeli attacks in 2025 - https://www.middleeasteye.net/live-blog/live-blog-update/nearly-100-palestinians-killed-west-bank-israeli-attacks-2025

We have an opening in our #DataScience core @icr.ac.uk. The post will work on a breadth of topics across #cancer biology, but expertise in spatial data, single cell and data integration are priorities. Details here: jobs.icr.ac.uk/vacancies/11... @jobrxiv.bsky.social

Happy to post our first preprint in a while! www.biorxiv.org/content/10.1.... This was a slightly new direction for us, spearheaded by amazing post-doc @audreylumeau.bsky.social. Short thread to follow 🧬

High levels of DNA replication initiation factors indicate ATR inhibitor sensitivity via excessive origin firing https://www.biorxiv.org/content/10.1101/2025.02.27.640046v1

Hibs fans yesterday showed Israeli Genocide the Red Card 👏🟥🇵🇸

We have another PhD project at @qmbci.bsky.social, within @cruk-cityoflondon.bsky.social RadNET, to understand how POLE3 promotes Double Strand Break repair and resistance to radiotherapy ! get in touch if you are interested in a PhD in genome stability ! crukradnet.colcc.ac.uk/phd-students...

Check out our super cool paper on aneuploidy in cells lacking Bub3. Congratulations to fantastic student Pallavi Gadgil and alum Olivia Ballew. journals.plos.org/plosgenetics...

Proteogenomic analysis of evolved aneuploid cell lines & primary tumors reveals cancer adaptive strategies for alleviating aneuploidy consequences – including increased expression of DNA replication & repair factors & of FOXM1 targets Zuzana Storchova and coworkers www.embopress.org/doi/full/10....

www.theguardian.com/world/2025/f... Ethnic cleansing, one village at a time

It pains me to say this as the son of a Holocaust survivor who has lectured on genocide prevention at Auschwitz where my mom lost dozens of her family, but Israel is seeking ‘lebensraum’ to create a Greater Israel & is using genocide & ethnic cleansing to do so with the active support of the West 😢

Delighted our work using aneuploidy as a biomarker of colorectal cancer risk in inflammatory bowel disease is out: gut.bmj.com/content/earl... The initial reaction from patients&families has been overwhelming Led by Ibrahim AlBakir @yosoykit.bsky.social @cancerresearchuk.org @icrlondon.bsky.social