We’re excited to reveal that team CAUSE led by Ludmil Alexandrov at @ucsandiego.bsky.social has been selected by @cancergrand.bsky.social to receive up to $25m over approx 5 years to take on one of cancer’s toughest challenges. Congratulations @mstaylor.bsky.social from IGC & team: edin.ac/4kYC1iR

📰 News announcement! www.cancergrandchallenges.org/new-teams-an... We’re thrilled to welcome five world-leading scientific teams, each awarded up to £20 million, to take on some of the toughest unanswered questions in #CancerResearch. Find out more about the teams and their challenges.

A huge thank you to everyone who contributed to our research, education and other activities in 2025. Special thanks to those of you working over the holiday. IGC is closed from 5pm today until 9am on 5 January but we will be sharing some highlights from 2025. Wishing you a restful festive break!

Join me and many human genomicists in Athens next April for an exciting program of the Human Genome Meeting!

Family was an important theme of two talks by @jorisveltman.bsky.social & Charlie Lees at our Inaugural Lecture Showcase, where they shared their research and career journeys so far. Thanks to everyone who attended! @cmvm-edinburghuni.bsky.social

So excited to be funded by @erc.europa.eu to work with this extraordinarily talented group of scientists on the GeneMotors project - unravelling how SMC motors work, how they are regulated and how they regulate gene expression. @ceesdekker.bsky.social @uoe-igc.bsky.social

Early-bird registration is until December 14th! Register now for Human Genome Meeting 2026, which will take place at the Zappeion Hall in Athens, Greece. The main program will be held on April 22–24, 2026, with a trainee symposium on April 21. For more information, please visit hugo-hgm2026.org!

Interested in ME/CFS research? Want to do a PhD with @aryback.bsky.social, @avakhamseh.bsky.social, @sjoerdvbeentjes.bsky.social & @cgatist.bsky.social? Then apply for a *funded* Future Medicine PhD Fellowship. See: www.findaphd.com/phds/project... Please contact us to discuss before applying.

Looking for a new opportunity in computational genomics? Join our group @uoe-igc.bsky.social @edinburgh-uni.bsky.social Deadline September 1! elxw.fa.em3.oraclecloud.com/hcmUI/Candid...

This is an exciting opportunity for anyone interested in computational genomics, epigenetics, cancer biology or the myeloma genome to join @anetamikulasova.bsky.social in her new myeloma research group at #IGC 👇

Amazing postdoctoral position for enthusiastic computational genomicist! @uoe-igc.bsky.social @edinburgh-uni.bsky.social

Welcome to the ESHG 2025 – #hybridconference! Join the conversation by using #eshg2025. With this hashtag you will also find the latest updates. See you at 8:30 CEST for the first sessions of today!

The #eshg2025 virtual platform & the ESHG 2025 app are now online! Read through our tips of using the platform, check out the conference programme and prepare your visit to Milan today: 2025.eshg.org/myconference...

We are hiring! Want to join my new group at the amazing @uoe-igc.bsky.social and perform ground-breaking studies in reproductive genomics and genomic medicine as a computational genomicist? Please DM me to discuss this, I will be attending #ESHG2025 elxw.fa.em3.oraclecloud.com/hcmUI/Candid...

On #InternationalOvarianCancerDay, we held a Shining a Light on Ovarian Cancer event where Professor Charlie Gourley, Dr Rob Hollis and Dr Sarah Taylor talked about how their research is driving personalised patient care & BBC journalist Christine Macleod shared her story of going through treatment.

The ESHG Award, ELPAG Award and the Mendel Lecturers of the #eshg2025 #hybridconference have talked to Mary Rice. Read the interviews and find out more about their backgrounds: 2025.eshg.org/speakers/spe...

The May issue of the European Journal of Human Genetics @ejhg_journal is now available online! Explore the latest advances in #humangenetics and discover fresh perspectives in #genomicsresearch: www.nature.com/ejhg/volumes...

HUGO warns that US science funding cuts threaten global advances in genomics, rare disease diagnosis, and public health. Sustained investment is crucial to ensure genomic benefits reach everyone. For more information: pubmed.ncbi.nlm.nih.gov/40287694/ #genomics #researchfunding

Read more about this study by @jmarshlab.bsky.social 👇

The largest ever genome-wide association study on osteoarthritis has advanced understanding of the disease and laid the groundwork for developing more effective and personalised therapies that could transform osteoarthritis care: edin.ac/43HK39g @genscot.bsky.social @www.helmholtz-munich.de

The #eshg2025 invites you to submit a Breaking Abstract for inclusion in the "Late Breaking Abstracts" Concurrent Session on Monday, May 26, 2025, 10:30-12:00 hrs CEST! Deadline: April 9, 2025, 23:59 CEST. For more information visit our website:

Congratulations to Professors Pleasantine Mill @cilialab.bsky.social and Sara Brown who have been elected as Fellows of the @royalsoced.bsky.social

‪New study investigates genetics of urinary metabolites - researchers at IGC and @helsinki.fi identified 54 genetic associations with the levels of different metabolites in urine. @genscot.bsky.social Read more here: edin.ac/42ekQC1

Do you want to play a pivotal role in groundbreaking research at IGC? In this role you will work at the intersection of computational and experimental science, leveraging cutting-edge technologies to address fundamental questions in genetics and disease. Apply by 31 March: edin.ac/3R5dEBU

March is #OvarianCancerAwarenessMonth. IGC researchers are leading significant advancements in our understanding of the disease. Dr Robb Hollis has written about work being undertaken at the Nicola Murray Centre for Ovarian Cancer Research into uncommon types of ovarian cancer: edin.ac/4jBEcId

“I have been privileged to conduct research at one of the top universities in the world, and I hope one day to be in a position where I can improve scientific education and research in Palestine.” Roza Masalmeh's journey from Palestine to Edinburgh: edin.ac/3XhStjB @cmvm-edinburghuni.bsky.social

👉 Do follow us on our social media accounts to stay updated

Forcing authors to edit or retract papers simply because they contain ‘forbidden terms’ is damaging to scientific integrity, says ESHG Read the statement from #eshg:

This week's editorial and cover at @thelancet.bsky.social www.thelancet.com/journals/lan... "The past 3 weeks have generated much anger, fear, and sorrow—but it is no time for panic. The medical and scientific communities must come together and stand up for this vision."

"It’s like being a detective - but working with the secrets of DNA!" Riya Madan is a first-year PhD student at @edinburgh-uni.bsky.social. Her work combines hands-on experiments in the lab and solving patterns with lines of codes. Read more here: edin.ac/4gwUfEm

Today is #WorldCancerDay. At IGC, researchers are leading significant advancements in our understanding of the disease. Dr Robb Hollis writes about research at the Nicola Murray Centre for Ovarian Cancer Research into uncommon types of ovarian cancer: edin.ac/4jBEcId

Well done @fogenomics.bsky.social another fantastic meeting ✨ Caught up with so many friends 🙏 Great speakers and even better networking 🧬🧬 #FOG2025 See you all in July at Genome Science, in Newcastle 🥳

Abstract submission deadline extended to Monday, February 03, 23:59 hrs CET (no exceptions). Last chance to submit an abstract for inclusion in the programme of #eshg2025 #hybridconference! More information on: t.co/26f98JviOZ

"With this experience, I feel more confident than ever that I’m on the right path to a career where I can make a meaningful impact through both clinical work and research." Read about Alsadeg Bilal's experience of the TRACC MB-PhD Programme: bit.ly/3Cp8HAj. Apply by 17 March: bit.ly/4h1oK6f.

When 2 males have a baby that reaches adulthood (mice with extensive genome editng)) www.cell.com/cell-stem-ce...

Spatial multi-omics has just gone to the next level! www.nature.com/articles/s41... www.nature.com/articles/s41... —Integration of 5 omic modalities w/ spatial resolution at 20 -50 μm —"a new era for characterizing tissue & cellular heterogeneity that single-modality studies alone could not reveal"

Two more days until the abstract submission deadline for #eshg2025 #hybridconference! Do not forget to submit your abstract until Thursday, January 30, 2025, 23.59 h CET. All information can be found on our website: t.co/hW4inHNm2j

One more week until the abstract submission deadline for #eshg2025 #hybridconference! Do not forget to submit your abstract until Thursday, January 30, 2025, 23.59 h CET. All information can be found on our website: 2025.eshg.org/abstracts/ #genetics #genomes

What DNA variants alter transcription factor (TF) binding affinity? Here, we describe a new workflow baal-nf. We used it to trawl through 6017 ChIP-Seq data sets for 558 TFs and 46 genotyped cell lines, finding 298,783 allele-specific binding sites (ASBs). www.biorxiv.org/content/10.1... 1/2

Up to 4 funded @cancerresearchuk.org positions are available for @edinburgh-uni.bsky.social or @uofglasgow.bsky.social MBChB students on completion of their intercalated BMedSci. Email: [email protected] or [email protected]. Read more here: bit.ly/4h1oK6f

"The science of extreme longevity continues as an immense joke." —The first man to “survive” past 110 actually died at 65. —Blue zones are a myth —Pervasive false claims about longevity and supercentenarians Gift link www.nytimes.com/2025/01/20/o...

Important Covid editorial @science.org by Maria Van Kerkhove www.science.org/doi/10.1126/...

@eshg.bsky.social abstract deadline is now almost *exactly* 2 weeks away... What have you all got up your sleeves for this year? See you in Milan?

Have a look at our latest work on PacBio LRS showing its potential as a single technology to accurately identify all types of clinically relevant variants. www.sciencedirect.com/science/arti...

We are hiring a new postdoctoral bioinformatician! Come and work with us on multidisciplinary cancer genomics projects at the Institute of Genetics and Cancer in Edinburgh: elxw.fa.em3.oraclecloud.com/hcmUI/Candid... institute-genetics-cancer.ed.ac.uk semplelab.com

Researchers uncover crucial role played by the integrity of the nucleus in cancer-induced aging: bit.ly/4h1VcFi @wbickmor.bsky.social

Well isn't this cool??? www.medrxiv.org/content/10.1... Variants in RNU4-2 and RNU6 paralogues could account for up to 1.2% of undiagnosed retinitis pigmentosa cases! Really neat example of pleiotropy: different RNU4-2 variants underlie neurodevelopmental disorder (ReNU syndrome) and RP. 🤓🧬🖥️🩺❤️

Time for a change! Dear @newcastleuni.bsky.social colleagues, many thanks for your company, support and advice in the last 8 years. It has been wonderful working with you in the Biosciences Institute, the wider faculty of medical sciences and in all things global!