Check out our new BioRepli-seq technique in this invited article related to our recent KMT2C/KMT2D replication timing study ⬇️. We use click chemistry–based biotinylation and on-bead library prep to comprehensively profile genome-wide DNA replication timing. 🔗 star-protocols.cell.com/protocols/4439

Summary Table of the massive defunding of biomedical research in the United States www.nytimes.com/interactive/...

Dr. Cooperberg receives ASPI’s 2025 Special Award for Patient Advocacy for leading a successful campaign to restore Active Surveillance in prostate cancer guidelines. youtu.be/ZHQIkIze6k8?... Check out his presentation on "Active Surveillance: Past, Present, and Future": youtu.be/ev1WcQ1Ucic?...

This one hits different these days: www.youtube.com/watch?v=MBH-... #TheFlamingLips #ResearchLife

Dress to kill. Come to see how I created a novel cancer vaccine by transferring MHC-peptide complexes from tumor cells to universal iPSC-derived Dendritic cells. #ISSCR2025 AI and Cancer Evolution Session, Friday 8:30am, Convention Hall B, level 1 @ucsfcancer.bsky.social @ucsfstemcell.bsky.social

great start to ISSCR annual meeting. great session on immune engineering this morning @isscr.org #isscr2025

We just got an email that Hopkins is freezing salaries, hiring, and some construction projects. In addition to the 800 million USAID we lost, we’ve had another 50 million in grants canceled so far. And a 2/3 year over year decline in funded grants despite an increase in submissions

Oof, just got notice HHMI is not even doing Hanna Gray Fellows, or any competition, this year due to the challenging times in science funding rn 😬 Understandable. On the bright side, I was really proud my application🌈 #science #nih #hhmi

Cell cycle duration determines oncogenic transformation capacity Tumours usually originate from a specific cell type in a given tissue; cell types that have faster cycles are more likely to become cancerous 🧪 www.nature.com/articles/s41...

A tour de force study from Taipale&Yin labs. It expands the vocabulary of the Regulatory Code by adding 1131 TF:TF composite motifs that are different from the individual TF motifs. The new composite motifs are enriched in cell-type specific elements and active in vivo www.nature.com/articles/s41...

For decades, NIH funding has fueled breakthroughs in cancer, heart disease and more. But a new policy puts progress at risk. We need Congress to oppose this abrupt change. Join me in emailing lawmakers today! #SaveNIHresearch bit.ly/4hxmfsK

Trump & Musk are making massive cuts to the National Institutes of Health. I know there is a lot going on right now, but this is one of worst things they have done so far, will affect cancer research and trials, the search for cures, innovation and competitiveness, our universities. Your lives.

🚨 New Paper Alert! 🚨 Our latest study on KMT2C/KMT2D (mutated in 20% of cancers) reveals a new function for H3K4me1 in regulating DNA replication timing (RT) and origin activity during cell state transitions. Check it out: www.cell.com/cell-reports.... More info ⬇️

Cancer Statistics 2025 are out! #prostatecancer incidence still on the rise, mortality basically flat. Get screened so you can get treatment _when needed_. #pcsm acsjournals.onlinelibrary.wiley.com/doi/epdf/10....

Really enjoyed this rigorous mechanistic study on the multifaceted principles of genome-wide heterochromatin maintenance during pluripotency from the Zaret lab (not on Bsky). Congrats to the authors: www.nature.com/articles/s41...

Huaigeng is presenting his exciting work on developing cancer vaccines today at the UCSF Prostate Program retreat.

I'm excited to share a new publication from my previous lab building on our earlier work on PROTAC degraders targeting MDM2 for cancer therapy. More efficient MDM2 degraders have been developed as we gain deeper insights into their mechanisms. Check it out if interested! pubs.acs.org/doi/full/10....

Glad to see @robertblelloch.bsky.social over here, outstanding mentor and scientist. Follow him, and also check out his lab account: @rblellochlab.bsky.social

ok, I tried to make a starter pack on genome stability/DNA replication/DNA repair etc. Sorry if I couldn't find someone, please nominate yourself and your colleagues in comments or DMs, looking forward to connecting with everyone! go.bsky.app/9jdDNxG

The Blelloch Lab held a retreat in the Tahoe National Forest this weekend. We decided to join the Bluesky Science Community.

Gotta say this place got a billion times more interesting in the last few days. Let’s get everyone who we care about over here!

So excited to see this released to the world! We've been talking about a new @nf-co.re manuscript for years - in the end it all came about rather quickly thanks to the collaboration with #EuroFaang! Have a read and please share widely - this is a great opportunity to reach new audiences!

Thank you to International Society for Stem Cell Research and Kendra Prutton for representing me and my research. I am proud to be part of this impactful and enriching community. www.isscr.org/isscr-news/m...

Exciting news! 🧬🎄Our latest preprint on a new MLL3/MLL4 function in DNA replication timing is out: biorxiv.org/content/10.1... Grateful for this teamwork with Ryan Boileau, Kayla Lenshoek, Robert Blelloch. @UCSF, @UCSFstemcell, @UCSFUrology, @UCSFCancer