🚨 New Paper Alert! 🚨 Our latest study on KMT2C/KMT2D (mutated in 20% of cancers) reveals a new function for H3K4me1 in regulating DNA replication timing (RT) and origin activity during cell state transitions. Check it out: www.cell.com/cell-reports.... More info ⬇️

Excited about the release of my lab's first paper🎉https://shorturl.at/ftC4f today, in print soon. many thanks to @bwfund.bsky.social NICHD/NIH UCSFPathology, @mdphdequity.bsky.social #UCSFWatsonScholar UCSFLiverCenter @ucsfstemcell.bsky.social for support in the first year of sangokoyalab.ucsf.edu

Excited to see this new #glycotime work from #proudofalumni Simon Wisnovsky's lab at UBC, identification of ST3GAL4 as mediator of Siglec-9 ligand biosynthesis in AML cells, which promotes immune evasion especially of macrophages. www.nature.com/articles/s41...

In vivo CRISPR screens identify key modifiers of CAR T cell function in myeloma https://www.biorxiv.org/content/10.1101/2024.11.19.624352v1

Huaigeng is presenting his exciting work on developing cancer vaccines today at the UCSF Prostate Program retreat.

The Blelloch Lab held a retreat in the Tahoe National Forest this weekend. We decided to join the Bluesky Science Community.

I'm excited to share a new publication from my previous lab building on our earlier work on PROTAC degraders targeting MDM2 for cancer therapy. More efficient MDM2 degraders have been developed as we gain deeper insights into their mechanisms. Check it out if interested! pubs.acs.org/doi/full/10....