Robert Blelloch
@robertblelloch.bsky.social
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Peter R. Carroll Distinguished Professor and Vice Chair of Research of Urology, UCSF
great start to ISSCR annual meeting. great session on immune engineering this morning
@isscr.org
#isscr2025
4 months ago
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Robert Blelloch
HuaigengXu
4 months ago
Dress to kill. Come to see how I created a novel cancer vaccine by transferring MHC-peptide complexes from tumor cells to universal iPSC-derived Dendritic cells.
#ISSCR2025
AI and Cancer Evolution Session, Friday 8:30am, Convention Hall B, level 1
@ucsfcancer.bsky.social
@ucsfstemcell.bsky.social
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Robert Blelloch
Deniz Gökbuget
8 months ago
🚨 New Paper Alert! 🚨 Our latest study on KMT2C/KMT2D (mutated in 20% of cancers) reveals a new function for H3K4me1 in regulating DNA replication timing (RT) and origin activity during cell state transitions. Check it out:
www.cell.com/cell-reports...
. More info ⬇️
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KMT2C/KMT2D-dependent H3K4me1 mediates changes in DNA replication timing and origin activity during a cell fate transition
Gökbuget et al. use machine learning to quantify chromatin state changes that predict DNA replication timing changes during cell differentiation. By following up on top predictors through functional v...
https://www.cell.com/cell-reports/fulltext/S2211-1247(25)00043-9
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Robert Blelloch
Blelloch Lab UCSF
10 months ago
Huaigeng is presenting his exciting work on developing cancer vaccines today at the UCSF Prostate Program retreat.
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