Shellie Fravel, PharmD
@shelliefravel.bsky.social
📤 100
📥 96
📝 44
Pharmacist | Clinical Professor ✨Interest in Nephrology Medicine
#NephJC
#NephSky
reposted by
Shellie Fravel, PharmD
American Journal of Kidney Diseases
5 days ago
GFR Measured With Computerized Tomography Urography in Healthy Individuals and Patients With CKD
bit.ly/3XsLlQY
#OpenAccess
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GFR Measured With Computerized Tomography Urography in Healthy Individuals and Patients With CKD
Opportunistic computed tomography (CT)-based screening is the practice of exploiting incidental imaging data for prevention, risk profiling, or presymptomatic detection of relevant disease unrelated…
https://bit.ly/3XsLlQY
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2
Shellie Fravel, pharmacist joining from Iowa City, no COI
#nephjc
12 days ago
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reposted by
Shellie Fravel, PharmD
Jordy Cohen
13 days ago
Excited to share our research letter published today in JAMA on the new Apple Watch Hypertension Notification Feature!
jamanetwork.com/journals/jam...
1/n
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Smartwatch and Hypertension Notification
This cross-sectional study assesses the potential impact of a smartwatch hypertension notification feature for US adults who have not been diagnosed with hypertension.
https://jamanetwork.com/journals/jama/fullarticle/2844767
1
13
10
reposted by
Shellie Fravel, PharmD
Nephrology Journal Club
14 days ago
Hey
#NephSky
2/10/26 at 9 pm EST we'll discuss
#Flozinating
into the Future & Beyond... SGLT2i in kidney transplant recipients. What's the latest evidence of risk/benefit? Do
#Flozins
act mechanistically the same in de-innervated kidneys? Come chat.
www.nephjc.com/news/inifinti-flozins-transplant
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To INFINITI and Beyond: SGLT2 Inhibitors in Kidney Transplant Patients — NephJC
This week, we aim for an INFINITe allograft lifespan. or flozination in kidney transplant.
https://www.nephjc.com/news/inifinti-flozins-transplant
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9
10
reposted by
Shellie Fravel, PharmD
Joel Topf
25 days ago
PBFluids▶️PISCES showed a striking cardiovascular benefit with fish oil in hemodialysis. Lovaza closely matches the trial’s ethyl-ester formulation, is FDA regulated, EHR friendly, and offers a practical option while we wait for the exact formulation
pbfluids.com/2026/01/why-...
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Why aren’t you prescribing fish oil to your dialysis patients?
PISCES showed a striking cardiovascular benefit with fish oil in hemodialysis. Lovaza closely matches the trial’s ethyl-ester formulation, is FDA regulated, EHR friendly, and offers a practical, re…
https://pbfluids.com/2026/01/why-arent-you-prescribing-fish-oil-to-your-dialysis-patients/
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11
3
reposted by
Shellie Fravel, PharmD
Nephrology Journal Club
26 days ago
Up next on #NephJC we will be unpacking SGLT2i in transplant recipients👇
journals.lww.com/cja...
#NephJC
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Shellie Fravel, pharmacist signing on from Iowa City, no COI
#nephjc
26 days ago
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reposted by
Shellie Fravel, PharmD
Nephrology Journal Club
27 days ago
🍌🥑Can pushing K⁺ to the high-normal range reduce ICD shocks and hospitalizations? 🎨
#Visualabstract
by
@jeyakumarmeyyappan.bsky.social
⏰
#NephJC
chat on Jan 27, 9 pm EST
www.nephjc.com/news/2026/1/...
0
13
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reposted by
Shellie Fravel, PharmD
Nephrology Journal Club
27 days ago
Oh, the weather outside is frightful 🥶🥶 But
#NephJC
is so delightful, and since you've no place to go
#NephSky
... Come discuss POTCAST: potassium goals and cardiac arrhythmias 1/27/26 at 9pm EST on
#Bluesky
Summary by
@shelliefravel.bsky.social
@salinesolut.bsky.social
www.nephjc.com/news/potcast
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POTCAST- K+ Pop and Arrhythmia Drop — NephJC
This week, we will discuss the POTCAST trial. It is a cardiology trial - but potassium belongs to nephrology.
https://www.nephjc.com/news/potcast
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10
reposted by
Shellie Fravel, PharmD
about 1 month ago
Sodium-Glucose Cotransporter-2 Inhibitors #SGLT2i and #Cardiorenal Events in #Nonalbuminuric Kidney Disease #VisualAbstract by
Augusto Cesar S Santos Jr
https://www.kireports.org/article/S2468-0249(25)00774-0/fulltext
#SGLT2i
#Cardiorenal
#Nonalbuminuric
#VisualAbstract
whuang0824
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3
3
reposted by
Shellie Fravel, PharmD
haysamrady
about 1 month ago
Can measuring glomerular filtration finally be easy?
#nephsky
#nephrology
www.kireports.org/article/S246...
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Can measuring glomerular filtration finally be easy?
Assessment of glomerular filtration rate (GFR) has progressed through a series of practical trade-offs between physiological accuracy and clinical feasibility. Direct measurement of GFR using exogenou...
https://www.kireports.org/article/S2468-0249(26)00019-7/fulltext?rss=yes
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8
3
reposted by
Shellie Fravel, PharmD
Nephrology Journal Club
about 2 months ago
It's 2026!🎉 We will be counting down the Top Ten Nephrology Stories of 2025 on 1/6/26 at 9 pm EST. Join us on TWITTER (it will always be Twitter to us). Come on by
#NephJC
faithful for a lively discussion! You picked & we're count'em down.
www.nephjc.com/news/2025/1/3/top-stories-in-nephrology-2025
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Top Stories in Nephrology 2025 — NephJC
2025 was rich in successful stories. Here are the top 10 that impressed our audience.
https://www.nephjc.com/news/2025/1/3/top-stories-in-nephrology-2025
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reposted by
Shellie Fravel, PharmD
Nephrology Journal Club
about 2 months ago
Did we (meaning "you" of course, because you voted) get them right? Is there something missing or is the order wrong?
#NephJC
#TopTenStories2025
Come discuss with an international cadre of nephrologists & other interested parties on 1/6/26 at 9 pm EST on
#Twitter
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reposted by
Shellie Fravel, PharmD
Melvin Chan
2 months ago
The future of nephrology
add a skeleton here at some point
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reposted by
Shellie Fravel, PharmD
Nephrology Journal Club
2 months ago
1/10 Last
#NephJC
we discussed dialysis frequency in AKI-D
#TenPostNephJC
We sought to answer an age-old question: Is less is really more? Or less is just simply what it is….less?
pubmed.ncbi.nlm.nih.gov/41201895/
1
8
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reposted by
Shellie Fravel, PharmD
Sabine Karam
2 months ago
The debate about kidney function estimation in cancer patients is not over. What is important to remember is that mCrCl is not mGFR
add a skeleton here at some point
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3
reposted by
Shellie Fravel, PharmD
Brian Rifkin
2 months ago
Less dialysis is…less dialysis.
#NephJC
Sure I’d like to see faster recovery and lower mortality. But what if conservative strategy is only “non-inferior”. Is that good enough, especially if dialysis is a limited resource like @nephroseeker.bsky.social says
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reposted by
Shellie Fravel, PharmD
Nephrology Journal Club
2 months ago
Join us for the last
#NephJC
of 2025, 12/16/25 at 9pm EST!🥳 How soon should we withhold dialysis in AKI? We're discussing the LIBERATE-D trial
#NephSky
This one might just change your mind 🧠🧠 Blog by
@msocomd.bsky.social
and
@sejalplakhani.bsky.social
www.nephjc.com/news/liberated-aki
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Dialyze Less, Recover More? AKI’s Chance to Get LIBERATE-D — NephJC
This week, we will discuss whether less is more when it comes to discontinuing dialysis in patients with AKI and a chance to recover.
https://www.nephjc.com/news/liberated-aki
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reposted by
Shellie Fravel, PharmD
Nephrology Journal Club
2 months ago
The LIBERATE-D VA by
@sejalplakhani.bsky.social
Should we break the pattern of thrice weekly dialysis in AKI-D?
#NephJC
#NephSky
www.nephjc.com/news/liberateva
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LIBERATE-D: The Visual Abstract — NephJC
In patients with dialysis-dependent acute kidney injury, a conservative dialysis strategy was evaluated in the LIBERATE-D trial. Could less be more? Join the discussion in #NephJC, but first, check ou...
https://www.nephjc.com/news/liberateva
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8
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reposted by
Shellie Fravel, PharmD
Swapnil Hiremath 🍁🇨🇦
3 months ago
Our take on the baxdrostat PA trial in
@asnpublications.bsky.social
#KidneyNews
www.kidneynews.org/view/journal...
with
@nephroseeker.medsky.social
and
@dramiliflores.bsky.social
! Thanks to Sam Kant and
@kdjhaveri.bsky.social
for the invite!!
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Shellie Fravel joining from Iowa City. No COI.
#NephJC
3 months ago
1
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0
reposted by
Shellie Fravel, PharmD
Nephrology Journal Club
3 months ago
Maybe the most shocking study from
#KidneyWk
. 🐚From the depths of the oceans to
#BlueSky
, we're discussing PISCES 🐟 12/2/25 9pm EST.
#NephJC
Are you hooked🪝on fish oil for CV disease in ESRD, or are you throwing it back 🌊?
www.nephjc.com/news/pisces-fishoil
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Fish Oil in Dialysis: A Big Catch or an Empty Net — NephJC
Holy Mackerel! This week we will discuss fish oil use in maintenance hemodialysis patients. Could this be the one thing that bends the curve on CV mortality, or is it just a red herring?
https://www.nephjc.com/news/pisces-fishoil
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reposted by
Shellie Fravel, PharmD
Nephrology Journal Club
3 months ago
Holy Mackerel! 🐟 🦜Ahoy matey! Could fish oil unlock the mysteries of increased CV mortality in ESRD? 🏴☠️
#NephJC
Join us for a lively trawling trip 12/2/25 🛥️at 9pm EST Check out the PISCES VA by
@brianrifkin.bsky.social
www.nephjc.com/news/piscesva
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PISCES: The Visual Abstract — NephJC
Curious how n-3 PUFAs may cut serious cardiovascular events in dialysis? 🐟 A big signal, a big dose, and a big discussion ahead — don’t miss this #NephJC! Check out the VA made by our master Brian...
https://www.nephjc.com/news/piscesva
0
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reposted by
Shellie Fravel, PharmD
Nephrology Journal Club
3 months ago
1/10 Last #NephJC we discussed the ORIGIN 3 trial which investigated the use of Atacicept in IgAN #TenPostNephJC Read the article 👇
www.nejm.org/doi/10....
#NephJC
1
9
9
reposted by
Shellie Fravel, PharmD
Nephrology Journal Club
3 months ago
In just 30 min we will start
#NephJC
chat on our @nejm.org trial tonight, we’ll explore IgAN treatment closer to pathophysiology ORIGIN with a simultaneous publication during
#KidneyWk
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A Phase 3 Trial of Atacicept in Patients with IgA Nephropathy | NEJM
IgA nephropathy, the most common primary glomerulopathy worldwide, is a kidney disorder of B-cell origin characterized by mesangial accumulation of IgA-containing immune complexes. In at least 50% ...
https://doi.org/10.1056/nejmoa2510198
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reposted by
Shellie Fravel, PharmD
Nephrology Journal Club
3 months ago
Tonite 11/18/25 on
#Bluesky
9pm EST We are discussing ORIGIN3 and atacicept in IgAN. APRIL, BAFF and B-cells, Oh My! (🦁🐯🐻) It's going to be Wicked good. 🧙♀️
#NephJC
Summary by
@notjustdialysis.bsky.social
www.nephjc.com/news/atacicept-origin3-gtfb36
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Attacking the Origin of IgAN: ORIGIN3 and Atacicept — NephJC
This week, we will discuss the phase 3 ORIGIN3 trial of atacicept, an APRIL/BAFF inhibitor for use in IgAN.
https://www.nephjc.com/news/atacicept-origin3-gtfb36
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reposted by
Shellie Fravel, PharmD
AIN/Sandipan Shringi
3 months ago
High measured GFR as a predictor of all-cause mortality and cardiovascular disease in a prospective non-diabetic population cohort More info:https://academic.oup.com/ndt/article/40/11/2091/8122110
@ndt-era.bsky.social
,
@hjanders.bsky.social
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High measured GFR as a predictor of all-cause mortality and cardiovascular disease in a prospective non-diabetic population cohort
ABSTRACTBackground. High glomerular filtration rate (GFR) is generally regarded as beneficial but has been associated with cardiovascular disease (CVD) and
https://academic.oup.com/ndt/article/40/11/2091/8122110
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2
2
reposted by
Shellie Fravel, PharmD
Swapnil Hiremath 🍁🇨🇦
4 months ago
Missing all the overwhelming amount of science coming out of
#KidneyWk
? The
#NephJC
crew has got you covered Day 2 edition
www.nephjc.com/news/kidneyw...
via
@nephroseeker.medsky.social
& moi
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Kidney Week in Houston: Day 2 — NephJC
in this edition: Fish Oil, GBD, Flozination meta-analysis, CHW intervention in Hispanic/Latino patients, and much more
https://www.nephjc.com/news/kidneywk25-day2
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reposted by
Shellie Fravel, PharmD
Edgar V. Lerma 🇵🇭
4 months ago
Indications for mineralocorticoid receptor antagonists (MRAs) in the management of cardio-kidney risk
#KidneyWk
#Nephpearls
#NephSky
#Cardiorenal
✅ Check out this resource from
@theisn.org
@isnkidneycare.bsky.social
👉
www.theisn.org/initiatives/...
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2
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reposted by
Shellie Fravel, PharmD
Kevan Polkinghorne 🇳🇿
4 months ago
Very proud to have lead the Australian arm of PISCES. Huge thanks for Charmaine Lok for the collaboration.
add a skeleton here at some point
0
5
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reposted by
Shellie Fravel, PharmD
Swapnil Hiremath 🍁🇨🇦
4 months ago
Got
#KidneyWk
FOMO like
@nephroseeker.medsky.social
? We got you covered with daily coverage of the simultaneous publications!
www.nephjc.com/news/kidneyw...
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Kidney Week in Houston: Day 1 — NephJC
in this edition: Atacicept in IgAN; Albuminuria as a surrogate outcome, Renal Remission and additional CONFIDENCE analysis
https://www.nephjc.com/news/kidneywk25-day1?ss_source=sscampaigns&ss_campaign_id=690e30e3095dd97ed06632c3&ss_email_id=690e321821a5a13e370035ca&ss_campaign_name=Special%3A+Kidney+Week+Day+1+coverage&ss_campaign_sent_date=2025-11-07T17%3A53%3A33Z
2
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11
Shellie Fravel, PharmD joining from Iowa City. No COI. Ready to learn lots tonight!
#NephJC
4 months ago
1
7
0
reposted by
Shellie Fravel, PharmD
Nephrology Journal Club
4 months ago
The 2025
@kdigo.org
IgAN guideline quietly redraws the map: new drugs, new thresholds, and a sense that the era of “supportive care only” is finally over
#Nephsky
#Medsky
✍️Summary by
@thekidneywhisperer.bsky.social
and
@glomerican.bsky.social
www.nephjc.com/news/igan-kd...
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2025 IgAN KDIGO guidelines: fresh out of press, already aging gracefully — NephJC
This week, we will discuss the 2025 KDIGO IgAN guidelines. which the shift from supportive care to structured, evidence-based therapy
https://www.nephjc.com/news/igan-kdigo-2025
1
22
16
reposted by
Shellie Fravel, PharmD
Nephrology Journal Club
4 months ago
⏩ Next
#NephJC
is on IgA nephropathy
@kdigo.org
guideline 🎨 Nice visual summary by
@roxnonna23.bsky.social
www.nephjc.com/news/2025/10...
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KDIGO 2025 IgA guidelines - Visual Abstract — NephJC
KDIGO 2025 is here. IgAN management is evolving with precision risk tools, new therapies, and a stronger focus on kidney protection. Check out the visual abstract created by Natalia Nombera
https://www.nephjc.com/news/2025/10/27/kdigo-2025-iga-guidelines-visual-abstract
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reposted by
Shellie Fravel, PharmD
Nephrology Journal Club
4 months ago
Last
#NephJC
short on individual data meta-analysis showing that although we love flozins for their extensive benefits we actually don’t completely understand how they work
#Nephsky
✍️Meta by
@willkidney.bsky.social
& co 📝 Write up by
@nephroseeker.medsky.social
www.nephjc.com/news/2025/10...
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Empagliflozin, the kidney, and what we still don’t understand — NephJC
NephJC short on an empagliflozin meta-analysis
http://www.nephjc.com/news/2025/10/20/empa-ma
1
10
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reposted by
Shellie Fravel, PharmD
Jim Myers
4 months ago
A Review of the Management of Nephrolithiasis in Autosomal Dominant Polycystic Kidney Disease -
goo.gl/alerts/LioZE5
#GoogleAlerts
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A Review of the Management of Nephrolithiasis in Autosomal Dominant Polycystic Kidney Disease
Autosomal dominant polycystic kidney disease (ADPKD) is a chronic hereditary disorder and a major cause of end-stage renal disease (ESRD). Urolithiasis is a frequent complication in ADPKD and may cont...
https://goo.gl/alerts/LioZE5
0
2
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reposted by
Shellie Fravel, PharmD
Swapnil Hiremath 🍁🇨🇦
4 months ago
Here’s
@kidneyboy.bsky.social
take on that study
pbfluids.com/2009/02/jour...
#NephJC
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Journal Club: low protein diet
Effect of a very low protein diet on outcome: long-term follow-up.This is the long-term follow-up of the B group from the original MDRD study.Enrollment criteria:Age: 18-70Abnormal Cr 1.2-7 women 1…
https://pbfluids.com/2009/02/journal-club-low-protein-diet/
1
5
4
Shellie Fravel, PharmD joining from Iowa City. No COI…not a big fan of restricting or supplementing. Looking forward to a good discussion tonight!
#NephJC
4 months ago
1
5
0
reposted by
Shellie Fravel, PharmD
Rolando Claure
4 months ago
🫘 In advanced
#CKD
, protein supplementation boosts 📈 serum albumin (+1.76 g/L) & BMI (+0.29 kg/m²) but ❌ does not significantly improve health-related quality of life (HRQOL). 🔎 17 RCTs | 5699 screened ⚠️ Bias, short duration, heterogeneity
#NephJC
0
4
3
reposted by
Shellie Fravel, PharmD
Nephrology Journal Club
4 months ago
Check out the Spanish VA.
#NephSky
Como siempre muchas gracias
@dramiliflores.bsky.social
www.nephjc.com/news/2025/10/12/suplementacion-con-protenas-en-la-erc-el-resumen-visual
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Suplementación con proteínas en la ERC: El Resumen Visual — NephJC
¿La suplementación con proteínas mejora la calidad de vida en la ERC avanzada? Revisa este resumen visual creado por Marc Soco , que sintetiza una nueva revisión sistemática y metanálisis! ¡No olvi...
https://www.nephjc.com/news/2025/10/12/suplementacion-con-protenas-en-la-erc-el-resumen-visual
0
8
4
reposted by
Shellie Fravel, PharmD
Nephrology Journal Club
4 months ago
Check at the VA for our discussion of protein diet strategies by
@msocomd.bsky.social
. Is restricting protein in CKD and pushing protein in ESRD
#TWDFNR
?
www.nephjc.com/news/2025/10...
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Protein supplementation in CKD: The Visual Abstract — NephJC
We like protein, or do we? Low protein, high protein, supplements…what’s a nephrologist to do?
https://www.nephjc.com/news/2025/10/12/protein-supplementation-in-ckd-the-visual-abstract
0
13
13
reposted by
Shellie Fravel, PharmD
Nephrology Journal Club
4 months ago
🗓️Join us 10/14/25 as we discuss: Are you team PRO protein 💪 or team RESTRICT protein 🥗 The strategies seem to shift somewhat as CKD progresses to ESRD. What's the evidence say 🤔? 🕰️9pm EST only on Bluesky.
#NephSky
#MedSky
www.nephjc.com/news/proteins-eskd
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The Protein Pendulum in CKD: supplement or restrict? — NephJC
This week, we will discuss an old dilemma in nephrology. To restrict or supplement the proteins? Premise: advanced CKD and dialysis.
https://www.nephjc.com/news/proteins-eskd
1
14
11
reposted by
Shellie Fravel, PharmD
Nephrology Journal Club
5 months ago
T2g In fact, many GNs have a high risk of recurrence and were excluded from this study. Since the recurrence of IgAN was not unexpected, should those patients have been excluded from this protocol?
#NephJC
1
3
3
reposted by
Shellie Fravel, PharmD
Nephrology Journal Club
5 months ago
T1e: Tacrolimus was withdrawn completely at 1 year post-transplant, only if at ≥6 months donor mixed hematopoietic chimerism (≥5% donor WBCs in whole blood) was achieved. 🎨 Infographic by @nephromommy-akshu.bsky.social & @nephroseeker.medsky.social
#NephJC
2
10
3
Shellie Fravel joining from Iowa City. No COI. Excited to get started tonight!
#NephJC
5 months ago
0
4
0
reposted by
Shellie Fravel, PharmD
Nephrology Journal Club
5 months ago
Chimerism might just be the 🔑 to immune tolerance and ending the need for immunosuppression 🚫💊after transplantation 🫘. Join the discussion 9/30/25 at 9 pm EST on Bluesky
#NephSky
#MedSky
#NephJC
www.nephjc.com/news/chimera-tolerance-njqe334
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Chimerism and Immune Tolerance: Can We Says Goodbye to Immunosuppression? — NephJC
This week, we will discuss the use of creating chimeras to induce immune tolerance and its potential to decrease or eliminate the need for immunosuppression in kidney transplant recipients.
https://www.nephjc.com/news/chimera-tolerance-njqe334
0
17
14
reposted by
Shellie Fravel, PharmD
Joel Topf
5 months ago
I did a blog post about Apple's new Hypertension Detection System
pbfluids.com/2025/09/appl...
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1
16
8
reposted by
Shellie Fravel, PharmD
Swapnil Hiremath 🍁🇨🇦
5 months ago
It’s that time of the year!
www.nephjc.com/news/2025/9/...
#NephJC
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NephJC 2025 Fall Pledge Drive — NephJC
Help keep NephJC a vital, original, and unbiased source of medical education.
https://www.nephjc.com/news/2025/9/22/nephjc-fall-pledge-drive
0
8
6
reposted by
Shellie Fravel, PharmD
KDIGO
5 months ago
KDIGO is pleased to announce the publication of the 2025 IgA Nephropathy (#IgAN) and IgA Vasculitis (#IgAV) Guideline, along with its Executive Summary in
@kidneyint.bsky.social
. Download:
kdigo.co/KDIGO-IgAN-I...
Read in KI:
kdigo.co/KDIGO-IgAN-I...
Exec Summary:
kdigo.co/IgAN-IgAV-Gu...
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Should we be considering the variability of a person's BP? Growing evidence that more variability is linked to poor outcomes. Maybe something for the 2033 BP guidelines... Long‐Term Blood Pressure Variability and Physical Performance in Older Adults -
onlinelibrary.wiley.com/doi/10.1111/...
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https://onlinelibrary.wiley.com/doi/10.1111/jch.70139
5 months ago
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