Augusto Cesar S Santos Jr
@acssjr.bsky.social
π€ 499
π₯ 194
π 23
Postdoctoral researcher and nephrologist, driven by science (from the bottom of my kidneys!)
reposted by
Augusto Cesar S Santos Jr
25 days ago
Heterogeneity of #eGFR Slopes According to #Etiology, eGFR and UACR in a Large Cohort of #CKD #Patients #VisualAbstract by
Augusto Cesar S Santos Jr
https://www.kireports.org/article/S2468-0249(25)00706-5/fulltext
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reposted by
Augusto Cesar S Santos Jr
2 months ago
Freely downloadable paper shows biomarker dynamics vary between hypothermic (HMPOβ) and normothermic (NMP) perfusion in kidney transplants. Some biomarkers align across methods, but NMP provides key insights into function and reconditioning potential
tinyurl.com/35tdhj2s
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reposted by
Augusto Cesar S Santos Jr
28 days ago
Refusal patterns matter! Kidneys turned down by multiple patients preβcross-clamp face a 35% nonutilization rate. New data from 2022β23 shows how understanding these patterns could improve allocation and reduce wasted organs.
#OpenAccess
#TXPforAll
tinyurl.com/58jt6n6f
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reposted by
Augusto Cesar S Santos Jr
about 1 month ago
Recipient Human Leukocyte Antigen-DR #HLA Homozygosity and Access to #Quality #Kidneys #VisualAbstract by
Augusto Cesar S Santos Jr
https://www.kireports.org/article/S2468-0249(25)00679-5/fulltext
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reposted by
Augusto Cesar S Santos Jr
ISNkidneycare
about 1 month ago
ποΈ Check out the latest Global Kidney Care Podcast! In this episode, @acssjr.bsky.social interviews @runningkidneys.bsky.social on how AI is transforming the outlook for patients with AKI and how nephrologists can leverage it to improve patient care.
globalkidneycarepodc...
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Access the WKD Social Media toolkit and find lots of materials to boost your WKD 2026 campaign.
www.worldkidneyday.org/knowledge-ba...
#KidneyHealthMatters
#OurKidneyOurPlanet
#CheckYourCreatinine
#Prevention
#Protect
#Planet
#PublicHealth
@theisn.org
2 months ago
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Check at
@transplantation.bsky.social
The bioinformatic tool HLA-EP-RESOLVER accurately predicts antibody reactivity to rare HLA alleles using eplet analysis.
tinyurl.com/2m9nm6ek
#Transplantation
#High
#Resolution
#HLA
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3 months ago
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reposted by
Augusto Cesar S Santos Jr
3 months ago
The bioinformatic tool HLA-EP-RESOLVER accurately predicts antibody reactivity to rare HLA alleles using eplet analysis. Validated in sensitized patients, it helps identify acceptable/unacceptable antigens in the era of high-resolution donor typing.
#HLA
tinyurl.com/2m9nm6ek
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World Kidney Day 2026 starts now! Participate! Caring for people, protecting the planet!
#KidneyHealthMatters
#CheckYourCreatinine
add a skeleton here at some point
4 months ago
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Just 1 month to go until the 2026
#WKD
campaign officially kicks off! Stay tuned for updates. Get ready to join us in this movement for kidney health! Follow the @worldkidneyday site and social media pages!
www.worldkidneyday.org
@theisn.org
IFKF
#KidneyHealthMatters
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Homepage - World Kidney Day 2025
World Kidney DayRaising awareness of theimportance of our kidneysWho we areWKD 2025 Scientific EditorialAre Your Kidneys Ok?Detect early to protect kidney healthRead the 2025 Scientific EditorialKidne...
https://www.worldkidneyday.org
5 months ago
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Iβm thrilled to see the Graphical Abstract Video Presentations now featured on the KIR website!
www.kireports.org/video-do
Iβm deeply grateful to everyone who contributed to making this
#vision
a reality!
@theisn.org
@kidneyint.bsky.social
@kireports.bsky.social
#ThisIsISN
#KidneyHealthMatters
5 months ago
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reposted by
Augusto Cesar S Santos Jr
Brammah R Thangarajah
5 months ago
#ECNeph
@brammahin.@myadla. @Dilushiwijay @dra_miliflore @acssjr Similar presentation in Post Tx Pt But ..why is it so rare ? Why dont we see it often despite high use ? Thoughts ?
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reposted by
Augusto Cesar S Santos Jr
Brammah R Thangarajah
5 months ago
Proposed mechanism of hyperinflammation due to MMF
#ECNeph
@brammahin @myadla @Dilushiwijay @dra_miliflores
@acssjr.bsky.social
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reposted by
Augusto Cesar S Santos Jr
Brammah R Thangarajah
5 months ago
#ECNeph
@brammahin
@Dilushiwijay
@myadla
@acssjr
@dra_miliflores β οΈ Few warnings exist already
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reposted by
Augusto Cesar S Santos Jr
Brammah R Thangarajah
5 months ago
When you suspect MMF-hyperinflammation dont forget to exclude these
#ECNeph
@brammahin @myadla @Dilushiwijay @dra_miliflores
@acssjr.bsky.social
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reposted by
Augusto Cesar S Santos Jr
Brammah R Thangarajah
5 months ago
#ECNeph @brammahin @Dilushiwijay @myadla @acssjr @dra_miliflores
pubmed.ncbi.nlm.nih....
pubmed.ncbi.nlm.nih....
#ECNeph
βοΈ More than few reported cases exist
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reposted by
Augusto Cesar S Santos Jr
Brammah R Thangarajah
5 months ago
Differentiating fever from flare in lupus
#ECNeph
@brammahin @myadla @Dilushiwijay @dra_miliflores @acssjr NLR CRP/ESR ratio <2/2-15/>15 : <2 s/o infection
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reposted by
Augusto Cesar S Santos Jr
Brammah R Thangarajah
5 months ago
π₯ Could this be MAS in SLE? We are seeing it more often, ποΈ - Clues in clinical practice Fever Pancytopenia Organomegaly β¬οΈ ESR with disease activity
#ECNeph
@brammahin
@Dilushiwijay
@myadla
@acssjr
@dra_miliflores
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reposted by
Augusto Cesar S Santos Jr
Brammah R Thangarajah
5 months ago
βΉοΈTurns out patient has hypogammaglobulinemia βMMF related/disease related Ig A - 134 mg/dl ( 70-400) β¬οΈIg G - 669 mg/dL (700-1600) β¬οΈβ¬οΈIg M - 38 mg/dL (40-230) πDoes it explain all?
#ECNeph
@brammahin
@Dilushiwijay
@myadla
@acssjr
@dra_miliflores
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reposted by
Augusto Cesar S Santos Jr
Brammah R Thangarajah
5 months ago
#ECNeph
@brammahin @myadla @Dilushiwijay @acssjr @dra_miliflores
#ECNeph
Do you agree ? Post your final diagnosis .... Is it to do with IST ?
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reposted by
Augusto Cesar S Santos Jr
Brammah R Thangarajah
5 months ago
π¦ When do you think fever is of infection in origin? βοΈ Can we rule out all infections all the times? Say some hidden TB or a very timid virus. We need more markers.
#ECNeph
@brammahin
@Dilushiwijay
@myadla
@acssjr
@dra_miliflores
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reposted by
Augusto Cesar S Santos Jr
Brammah R Thangarajah
5 months ago
#ECNeph
@brammahin @myadla @Dilushiwijay @acssjr @dra_miliflores
#ECNeph
yet another admission ..in a weeks time premature discharge vs recurrence of infection /appearance of flare High inflammatory markers favour infection or is it non infectious inflammation
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reposted by
Augusto Cesar S Santos Jr
Brammah R Thangarajah
5 months ago
#ECNeph
@brammahin @myadla @Dilushiwijay @acssjr @dra_miliflores
#ECNeph
see the time line of admissions for febrile episodes Class switch High inflammatory markers Infection clues negative 3 episodes in 2-3 months Where should this lead to ?
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reposted by
Augusto Cesar S Santos Jr
Brammah R Thangarajah
5 months ago
π 3 admissions with acute febrile illnesses within 2-month span π©Ί No focal signs/symptoms β’οΈ Routine imaging -negative -No organ-specific illness
#ECNeph
@brammahin
@Dilushiwijay
@myadla
@acssjr
@dra_miliflores
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reposted by
Augusto Cesar S Santos Jr
Brammah R Thangarajah
5 months ago
#ECNeph
@brammahin @myadla @Dilushiwijay @acssjr @dra_miliflores
#ECNeph
Rx with antibiotics Restarted on IST after fever subsidence What next ? Evaluation being negative for all infections : Bacteria /virus .. How to go further ?
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reposted by
Augusto Cesar S Santos Jr
Brammah R Thangarajah
5 months ago
βοΈ What features would suggest SLE activity for you? βοΈ Do you weigh on global assessment?
#ECNeph
@brammahin
@Dilushiwijay
@myadla
@acssjr
@dra_miliflores
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reposted by
Augusto Cesar S Santos Jr
Brammah R Thangarajah
5 months ago
#ECNeph
@brammahin @myadla @ISNkidneycare @Dilushiwijay @acssjr @dra_miliflores ESR:CRP <2 S/O infection than flare Lupus. 2018 Jun;27(7):1123-1129
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reposted by
Augusto Cesar S Santos Jr
Brammah R Thangarajah
5 months ago
#ECNeph
@brammahin @myadla @ISNkidneycare @Dilushiwijay @acssjr @dra_miliflores Does the evaluation suggest flare ? All atypical infections ruled out Malignancy ?????? What else ? PET-CT ?
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reposted by
Augusto Cesar S Santos Jr
Brammah R Thangarajah
5 months ago
π£οΈFever in SLE - An enigma wrapped in mystery. Interested in hearing your phrases of fever and also how do you define it in routine practice? π§ Just basics
#ECNeph
@brammahin
@Dilushiwijay
@myadla
@acssjr
@dra_miliflores
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reposted by
Augusto Cesar S Santos Jr
Brammah R Thangarajah
5 months ago
How to differentiate between flare /Infection in SLE
#ECNeph
@brammahin @myadla @Dilushiwijay @dra_miliflores
@acssjr.bsky.social
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reposted by
Augusto Cesar S Santos Jr
Brammah R Thangarajah
5 months ago
#ECNeph
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reposted by
Augusto Cesar S Santos Jr
Brammah R Thangarajah
5 months ago
#ECNeph@brammahin@myadla
@ISNkidneycare @Dilushiwijay @acssjr @dra_miliflores How to differentiate flare /infection in SLE Infection versus disease activity in systemic lupus erythematosus patients with fever. BMC Rheumatol. 2024 Aug 14;8(1):34
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reposted by
Augusto Cesar S Santos Jr
Brammah R Thangarajah
5 months ago
#ECNeph@brammahin@myadla@ISNkidneycare@Dilushiwijay@acssjr@dra_miliflores Febrile admission in year time Flare vs infection ? Rx : Antibiotics ..Response + Whats the time of reinitiation of IST after infection ?
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reposted by
Augusto Cesar S Santos Jr
Brammah R Thangarajah
5 months ago
#ECNeph@brammahin@myadla@ISNkidneycare@Dilushiwijay@acssjr
@dra_miliflores Admitted in a weeks time with fever , polyarthralgia Is it relapse /recurrence of infection High inflammatory markers : is it SLE flare ?
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reposted by
Augusto Cesar S Santos Jr
Brammah R Thangarajah
5 months ago
#ECNeph@brammahin@myadla@ISNkidneycare@Dilushiwijay@acssjr@dra_miliflores Admitted with Febrile illness - Pneumonia Appropriate antibiotics given
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reposted by
Augusto Cesar S Santos Jr
Brammah R Thangarajah
5 months ago
#ECNeph@brammahin@myadla@ISNkidneycare@Dilushiwijay@acssjr@dra_miliflores Now Pt on triple IST with MMF /HCQ CyC not initiated -Young woman Proteinuria remission attained
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reposted by
Augusto Cesar S Santos Jr
Brammah R Thangarajah
5 months ago
#ECNeph
@brammahin @myadla @Dilushiwijay @acssjr @dra_miliflores @Dilushiwijay @ISNkidneycare Admitted with febrile illness Flare vs infection Any other DD ? Thoughts plz ! Mild rise in creatinine Kidney Bx : Now Class III LN
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reposted by
Augusto Cesar S Santos Jr
Brammah R Thangarajah
5 months ago
#ECNeph
@brammahin @myadla @ISNkidneycare @Dilushiwijay @acssjr @dra_miliflores Class switching in LN Bomback AS. Nonproliferative Forms of Lupus Nephritis: An Overview. Rheum Dis Clin North Am. 2018 Nov;44(4):561-569
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reposted by
Augusto Cesar S Santos Jr
Brammah R Thangarajah
5 months ago
#ECNeph
@brammahin @myadla @Dilushiwijay @acssjr @dra_miliflores @Dilushiwijay @ISNkidneycare Recap of EULAR -ACR criteria
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reposted by
Augusto Cesar S Santos Jr
Brammah R Thangarajah
5 months ago
#ECNeph
@brammahinv@myadla @Dilushiwijay @acssjr @dra_miliflores @Dilushiwijay @ISNkidneycare CNI based regimen started On HCQ Proteinuria remitting ... ...Non adherence
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reposted by
Augusto Cesar S Santos Jr
Brammah R Thangarajah
5 months ago
#ECNeph
@brammahin @myadla @Dilushiwijay @acssjr @dra_miliflores @Dilushiwijay @ISNkidneycare Is the diagnosis obvious ? Should we check labs? ANA+VE/low C3/hemat /Musculo skeletal involvement /Kidney Biopsy done in v/o proteinuria : Class 1 Can it be podocytopathy
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Starting in 20 min! Join us in this exciting case discussion
#ECNeph
add a skeleton here at some point
5 months ago
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reposted by
Augusto Cesar S Santos Jr
ISNkidneycare
6 months ago
ποΈ Check out the latest Global Kidney Care Podcast! The latest Kidney Care Podcast features Peter Kotanko on AI in nephrology. It kicks off a new series in the ISN Academyβs AI section, regularly updated with expert content and resources. Listen here:
share.transistor.fm/s/40d6b789
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reposted by
Augusto Cesar S Santos Jr
ISNkidneycare
6 months ago
Start preparing your abstract for the #ISNWCN 2026 (March 28β31 in Yokohama, Japan). Don't wait any longer, read more and submit your abstract by October 22 β‘οΈ
http://lite.spr.ly/6...
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reposted by
Augusto Cesar S Santos Jr
Canadian Society of Nephrology
6 months ago
Save the date! CSN homecoming on October 15th at the Toronto Airport Sheraton From 12 to 8 pm, program coming soon!
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reposted by
Augusto Cesar S Santos Jr
ISNkidneycare
8 months ago
Nephrology Health Professionalsβ Perspectives on their Preferred Modality for Scientific Meetings, Balancing Affordability, Sustainability, and Opportunities to Interact with Peers. 2025 from @kireports.bsky.social.
www.kireports.org/ar...
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reposted by
Augusto Cesar S Santos Jr
ISNkidneycare
8 months ago
ππ¦π‘ π©ππππ’ πππ¦π§π₯πππ§ π¦ππ₯πππ¦: Efficacy & safety of pegcetacoplan in kidney transplant recipients w/recurrent C3G or primary IC-MPGN: 12-week results: NOBLE study. 2025 @kireports.bsky.social
www.kireports.org/ar...
#VideoAbstract
by
@dilushiwijay.bsky.social
& Divya Bajpai
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reposted by
Augusto Cesar S Santos Jr
Cristina Popa
9 months ago
@kireports.bsky.social
article on nephrology meetings, and how can all aspects be ballanced π¨VA by
@acssjr.bsky.social
I hope
@asnkidney.bsky.social
will consider a hibrid
#Kidneywk
with extensive online coverage- travelling to US become risky/ difficult
www.kireports.org/article/S246...
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reposted by
Augusto Cesar S Santos Jr
ISNkidneycare
9 months ago
ππ¦π‘ π©ππππ’ πππ¦π§π₯πππ§ π¦ππ₯πππ¦: Insights from the BKEVER Trial comparing everolimus versus mycophenolate mofetil for BK Polyomavirus infection in kidney transplant recipients
www.kidney-internati...
#VideoAbstract
by
@raphapalma.bsky.social
&
@acssjr.bsky.social
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reposted by
Augusto Cesar S Santos Jr
ISNkidneycare
10 months ago
π¨
#Tweetorial
Alert! π¨ π¬ Rare Kidney Diseases: Unmasking the Zebras in Nephrology! π¦π‘ Join me, Dr. Mythri Shankar,
@nephromythri.bsky.social
as we explore fascinating, rare kidney diseasesβbecause not every kidney case is a horse! π Stay tuned! π§΅π
#NephTwitter
#RareKidneyDiseases
#MedEd
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