Study of 6 U.S. OPOs found 40,978 excluded clinically, leaving 4,480 suitable donors (7.5%–12.4%). Hospitals referred >99% of eligible cases, supporting referral-based donor potential measurement as a more accurate alternative to administrative methods. tinyurl.com/36s3kxzc

Pediatric-to-pediatric kidney transplants show strong adaptability: smaller donor kidneys grow rapidly—reaching age-appropriate size within ~6 months—and support good function, reinforcing this strategy as safe and effective. #TXPforAll #OpenAccess tinyurl.com/47797cac

#TBT to this week's featured top downloaded paper from 2024: Outcomes of DCD Liver Transplant Using Sequential Normothermic Regional Perfusion and Normothermic Machine Perfusion or NRP Alone Versus Static Cold Storage #Transplantation #Med tinyurl.com/4sbrvj5c

This paper shows that, despite better early outcomes, progress has plateaued in the last 50 years of kidney transplant data. Long-term graft survival is declining in the modern era due to older, more comorbid recipients and rising infection-related deaths. tinyurl.com/2p9ucusb

Genetic testing is reshaping kidney transplant evaluation: over one-third of candidates had a genetic diagnosis often clarifying cause and guiding donor decisions. #TXPforAll #OpenAccess #Transplantation tinyurl.com/3zuejwwc

A “lung-on-a-chip” model brings transplant research closer to reality replicating cold storage injury with human cells and revealing barrier loss, inflammation, and gene changes. A powerful new tool to study lung transplant injury and test therapies. tinyurl.com/3sphs9zf

This paper by @nerecugo et shows that a slow-release form of necrostatin-1 using PLGA microparticles helps to protect islets under stress preserving insulin function and reducing inflammation.#TXPforAll #Transplantation #OpenAccess tinyurl.com/3dp4p3by

#TBT to this week's featured top downloaded paper from 2025: Pregnancy After Solid Organ Transplantation: Review of the Evidence and Recommendations #Transplantation #Med tinyurl.com/5ae3a2f4

An “immune-guided” CMV strategy in kidney transplant recipients didn’t lower infection rates, but reduced CMV disease suggesting tailored prophylaxis based on immune response may improve clinically meaningful outcomes. #TXPforAll #Transplantation tinyurl.com/543jt738

New SLK/KAL allocation rules show promising results: few patients needed SLK, many recovered kidney function after liver transplant alone, and outcomes after SLK and KAL were similar. #TXPforAll #Transplantation #OpenAccess tinyurl.com/yzz3k9uz

Adding everolimus to CNI after #livertransplantation lowers cancer risk and remains cost-effective, despite a higher infection risk. #TXPforAll #Transplantation #Immunosuppression tinyurl.com/4xyjydya

#TBT to this week's featured top downloaded paper from 2025: Long-term Metabolic Outcomes Post–Simultaneous Pancreas-Kidney Transplantation in Recipients With Type 1 Diabetes #Transplantation #Med tinyurl.com/ycxnbyxa

REVIEW alert! Genetic testing can guide living kidney donor assessment but must complement clinical evaluation and involve counseling and shared decision-making to ensure safety. #TXPforAll #Transplantation tinyurl.com/c46nmb4t

NMP may not fully rescue livers after prolonged cold ischemia—longer storage led to poorer recovery or increased injury in a pig DCD model. #TXPforAll #Transplantation #OpenAccess tinyurl.com/4cprrnkz

Lower socioeconomic Status worsens kidney transplant access and outcomes in England but not in Northern Ireland showing care models drive equity. #TXPforAll #Transplantation tinyurl.com/3rm334d7

High Hb (concentrated blood) impaired cardiac function and increased hemolysis, while whole blood and plasma better preserved heart performance over time. 👉 Diluting Hb may be key to optimizing heart preservation during ex situ heart perfusion. tinyurl.com/4zhwz8kk

#TBT to this week's featured top downloaded paper from 2024: Health Disparity Metrics for Transplant Centers: Theoretical and Practical Considerations #Transplantation #Med tinyurl.com/42jxyvwt

👉Women, especially older women, often have reduced access from referral to waitlisting and transplantation. These differences in outcomes may reflect a combination of bias, biology, and gendered factors. #TXPforAll #Transplantation tinyurl.com/mr39422a

3 kidney transplants between identical twins performed with no immunosuppression ✅ Up to 22 years follow-up ✅ Excellent graft function ✅ No rejection episodes Supports immunosuppression-free transplant as a safe, effective option in monozygotic twins. tinyurl.com/5x67yx7d

👉Donor genetics matter, especially in HIV+ kidney transplant recipients. A single APOL1 risk variant in donors was linked to significantly worse outcomes (rejection/graft failure), with hazard ratios up to 10.1 across cohorts. #TXPforAll #Transplantation tinyurl.com/3uawa9xb

🚨 Kidney care gap: In South Africa, 79% of patients needing KRT received no treatment and were presumed dead. Access to dialysis/transplant favored younger, healthier, wealthier patients.💡 Transplant saves lives but capacity limits decide who gets it. tinyurl.com/3pujenpx

#TBT to this week's featured top downloaded paper from 2024: Sequencing of Physically Interacting Cells in Human Kidney Allograft Rejection to Infer Contact-dependent Immune Cell Transcription #Transplantation #Med tinyurl.com/4fn22sfc

The future of organ transplants? In #xenotransplantation, adding αIL-15 helped pig kidney grafts last longer in primates by reshaping NK cells — key drivers of rejection. 💡 Targeting the immune system smarter = better graft survival. tinyurl.com/5bu2ck6f

Retroperitoneoscopic nephrectomy . • Similar surgery time, blood loss & kidney size • BUT muscle damage was dramatically lower with RN • Better long-term cosmetic outcomes. RN + kidney transplant is safe, less invasive, and kinder to the body. tinyurl.com/3yn8bada

This paper shows a clear edge for ischemia-free liver transplantation over NMP 📊 Lower early graft dysfunction 📉 Fewer complications at 1 year 💚 Better survival 💡 IFLT may redefine the standard for liver transplant—especially with higher-risk donors. tinyurl.com/yzkuvsye

Can IVIG change the game for post-transplant antibody deficiency is addressed in this study. This shows adding IVIG to standard care may significantly reduce infections and boost humoral immunity in solid organ transplant recipients with secondary antibody deficiency.tinyurl.com/2dbv7mur

#TBT to this week's featured top downloaded paper from 2025: Circulating Tissue Specific Extracellular Vesicles for Noninvasive Monitoring of Acute Cellular Rejection in Clinical Heart Transplantation #Transplantation #Med tinyurl.com/8urr8m74

Freezing without ice? Supercooling at −10°C for days is a major scientific step-but in the era of machine perfusion, its clinical value still needs to be proven. The future may lie in hybrid preservation strategies on the path toward true organ banking. tinyurl.com/bdhn89zf

Analyzing gene expression in kidney transplant biopsies, study reveals clear molecular differences between rejection types; TCMR and AMR each show distinct gene signatures. Yet, patient-to-patient variability reminds us: rejection isn’t one-size-fits-all! tinyurl.com/y4djk7c3

The April issue of Transplantation features cutting-edge studies presented at the #WTC2025 with real clinical impact, from viruses to vaccines, offering new insights to improve care for transplant recipients. #TXPforAll #Transplantation tinyurl.com/3xxbakmu

This paper discusses what transplant patients are really talking about online. It explores 1,000 posts from Reddit’s transplant community and reveals how patients share experiences, seek support, and navigate life after solid organ transplantation. tinyurl.com/43fjaepk

#TBT to this week's featured top downloaded paper from 2024: CHALF Score: A Novel Tool to Rapidly Risk Stratify Children in Need of Liver Transplant Evaluation During Acute Liver Failure #Transplantation #Med tinyurl.com/2s3trazs

Can we improve organ preservation before transplant? 🧪 This review by @jordivengo highlights how adding extracorporeal blood purification (EBP) to ex situ organ perfusion helps remove waste, stabilize organs, and even extend preservation beyond 24h. tinyurl.com/n4ktw7jj

Over 20 years of data show that DCD islets perform as well as DBD islets—with a trend toward better diabetes reversal. A promising way to increase donor availability for type 1 diabetes treatment. #TXPforall #Transplantation tinyurl.com/4p255ryk

This study shows persistent socioeconomic disparities in England—affecting access, donor type, and outcomes—while Northern Ireland shows more equitable access. Healthcare delivery models clearly matter! #TXPforall #Transplantation tinyurl.com/mr7aj24c

Can alkaline phosphatase (ALP) protect donor kidneys? In a porcine model, adding ALP during preservation improved energy status and reduced metabolic stress after reperfusion. Promising strategy to reduce delayed graft function #TXPforAll #Transplantation tinyurl.com/muyxpww6

#TBT to this week's featured top downloaded paper from 2025: The Fourth International Consensus Guidelines on the Management of Cytomegalovirus in Solid Organ Transplantation #Transplantation #Med tinyurl.com/y3wffwxj

"Do kidney transplant outcomes differ among people living with HIV?" Gray et al. analyzed over 30,000 UK recipients to demonstrate the importance of accounting for ethnicity and socioeconomic deprivation when comparing outcomes. tinyurl.com/4umvrstk tinyurl.com/yz39cdcn

❤️ This study by Rosethal et al. shows that clinical follow-up + echocardiography (TDI) may safely monitor rejection, with high graft survival and low detection yield from routine biopsies. Less invasive care looks promising! #TXPforAll #Transplantation tinyurl.com/cnwc64wr

This review by Cantarelli et al. highlights how EPO promotes tolerance, dampens inflammation, and shapes T cells and macrophages in kidney disease and #transplantation. #TXPforAll #Immunology tinyurl.com/5x79n7b5

Milestone reached! Our community has grown to 11,000 followers on X/Twitter. Researchers, clinicians, & transplant enthusiasts around the world who share, discuss, & advance the science of transplantation together. Thank you for being part of this growing community! #TXPforAll

Does the logistics of normothermic machine perfusion matter in liver transplantation from donation after circulatory death donors is discussed in this paper by Alderete et al. #TXPforAll #Transplantation #OpenAccess tinyurl.com/4zjt47ae

#TBT to this week's featured top downloaded paper from 2024: Efficacy and Safety of Bleselumab in Preventing the Recurrence of Primary Focal Segmental Glomerulosclerosis in Kidney Transplant Recipients: A Phase 2a, Randomized, Multicenter Study #TXPforAll tinyurl.com/yc4munav

Highlights major advances in kidney transplantation @ #WTC2025. These advances include progress toward making machine perfusion, expanding access for highly sensitized patients through new desensitization strategies, & developing precision medicine tools. tinyurl.com/3wkpc9a8

The BEAT-BK Trial is putting Intravenous Immunoglobulin to the test as an add-on strategy to control BK polyomavirus in kidney transplant recipients aiming to fight the virus without risking rejection. #TXPforAll #Transplantation #OpenAccess tinyurl.com/4nhvvp4z

Donor–recipient age matching matters in liver transplantation. Analysis of UNOS data shows younger recipients have worse outcomes when receiving older donor livers, while older recipients are less affected, highlighting the need for smarter age-matching. tinyurl.com/ms5e4mus

The paper by Gerckens et al. discusses whether we can improve risk prediction after lung transplantation by personalizing lung function assessment #TXPforAll #LungTransplantation tinyurl.com/yc92w5yf

#TBT to this week's featured top downloaded paper from 2025: Pregnancy Outcomes Using Assisted Reproductive Technology in Kidney Transplant Recipients #Transplantation #Med tinyurl.com/zn2xna5v

Can we better predict viability of DCD donor hearts? This study by Saemann et al. study shows that combining laser Doppler perfusion shifts with venous lactate during ex vivo blood perfusion can accurately predict post-transplant heart function. #TXPforAll tinyurl.com/48wbkbtv

Frailty in kidney transplant candidates depends heavily on how you measure it, and current tools don’t agree. It’s time for a standardized approach to make evaluation and listing fairer and more consistent. #TXPforAll #Transplantation tinyurl.com/42y8pw63