Glad to have discussed the case for #ECNeph. Thank you all for your support and guidance! @myadla.bsky.social @dramiliflores.bsky.social @dilushiwijay.bsky.social @theisn.org 🙌

🚨 Cardiorenal Syndrome (CRS): A Deadly Duo 🚨 Did you know the heart & kidneys are so intertwined that dysfunction in one can wreak havoc on the other? Let's dive into CRS today. A lucid read for every nephrology & cardiology fellow 🫀🩺 #MedTwitter #ISNTweetorial

Hi this is Dilushi, joining a bit late! And lurking tonight #ECNeph

“Now we must… turn words into actions: We need steady investment, teamwork across sectors, and real action in every corner of the globe. This isn’t just about better kidney care -it’s .. making healthcare fairer & more accessible for everyone, especially in LMICs that need it most.” 👏🎉

🌍 History made! For the first time, kidney care is on the global health agenda. #WHA78 adopted a landmark resolution recognizing kidney health in the fight against #NCDs. 👏 Thanks to Guatemala and the global kidney community for making this possible! #KidneyHealthMatters

longer discussion including MRAs and ASIs here www.nephjc.com/news/2024/10... #WorldHypertensionDay

BP Targets: the @kdigo.org www.nephjc.com/news/kdigo-bp The ESPRIT trial discussion www.nephjc.com/news/esprit The BPROAD discussion www.nephjc.com/news/bproad #WorldHypertensionDay #120ForAll

The @thelancet.com review on global BP control www.thelancet.com/journals/lan... Worsening BP control in Canada www.sciencedirect.com/science/arti... Improving BP control in US from @amjhypertension.bsky.social academic.oup.com/ajh/article/... #Hypertension #WorldHypertensionDay

K issues #NephJC www.nephjc.com/news/salt-su... Podcast www.nephjc.com/freelyfilter... K switch mechanism pubmed.ncbi.nlm.nih.gov/38081406/ in @ajkd.bsky.social pubmed.ncbi.nlm.nih.gov/37772757/ from @amjhypertension.bsky.social journals.physiology.org/doi/full/10.... #WorldHypertensionDay

The ARNI data in CKD here pubmed.ncbi.nlm.nih.gov/30002098/ #WorldHypertensionDay

#23 𝗦𝗔𝗩𝗘 𝗧𝗛𝗘 𝗗𝗔𝗧𝗘 for next Space #WorldHypertensionDay: "Hypertension and the Kidneys." @edgarvlermamd.bsky.social @hswapnil.medsky.social @myadla.bsky.social @dilushiwijay.bsky.social @ferarceamare.bsky.social 🗓️ May 22 🕑 3:00 pm CEST ⏰ Set your alarm here: twitter.com/i/spaces/1jM...

Great meeting with the @ISNEducation social media team; lots of exciting projects on the horizon! We're looking forward to what’s coming next, so stay tuned!

Guatemala's resolution on kidney health: a historic opportunity - The Lancet www.thelancet.com/journals/lan... Tonelli et al: "We call on all 193 UN Member States to bring about positive change by voting to adopt Guatemala's resolution on kidney health at the 78th WHA in May, 2025."

#AcademicSky #AcademicPublishing #AcademicChatter

📅 Get ready for the next #NephJC on May 29 🧠💊 We’ll dive into: Lorundrostat for Uncontrolled Hypertension — efficacy, safety, and what it means for the future of BP management. ⏰ #NephSky #MedSKy @nejm.org www.nejm.org/doi/ful...

#NephJC One of my fave all time papers in this topic is a proof-of-concept DDAVP in CKD: reduces bleeding time consistently @nejm.org pubmed.ncbi.nlm.nih.gov/6401193/

Don´t forget to advocate the resolution led by Guatemala on #WHA78: 🌍 Chronic kidney disease affects over 850M We must shift from silent neglect to strategic action. Awareness, prevention, and equity in care are our next steps. #NephJC @theisn.org #NephSky #MedSky www.thelancet.com/jo...

One the one hand, low risk intervention. On the other hand, still unclear benefits. We doctors like to feel like we are doing something to prevent bad outcomes…but “don’t just do something, sit there” is also appropriate in many patients #NephJC

🩸Desmopressin appears safe, any serious risks? Hyponatremia, headaches, hemoglobin drop 🧪 We need stronger data on who, when, and how much. #NephJC

#NephJC pubmed.ncbi.nlm.nih.gov/7702050/

I do that too. If severe AKI or CKD stage 5 knocking the uremia door I lower my HD threshold. That’s an area where data are needed though #NephJC

specific studies comparing the efficacy of different administration routes is limited in kidney biopsy, in some cases for hematological disorder better SC #NephJC

🧪 Two RCTs, one question… very different paths: 🔹 Same drug 🔹 Different patients 🔹 Different doses 🔹 Different needles 🔹 Different expectations Feeling any twist ahead? #NephJC

🩸Kidney biopsy is essential for diagnosis, but bleeding remains a key concern — especially in CKD, and when it comes to preventing bleeding? On 2019 @ajkd.bsky.social core curriculum left us without clear guidance. #NephJC

🎨Beautiful visual abstract by Divya Bajpai #NephJC http://www.nephjc.co...

Hi this is Dilushi, nephrologist from Colombo! First time joining #nephJC on Bluesky! No COI

📖 This weekend don't miss our @kireports.bsky.social #ISNFridaySelection: Open-Label, Randomized, Controlled, Crossover Trial on the Effect of Dapagliflozin in Patients With ADPKD Receiving Tolvaptan www.kireports.org/ar...

Iptacopan reduces proteinuria and stabilizes kidney function in C3 glomerulopathy. 2025 from @kireports.bsky.social www.kireports.org/ar... #VideoAbstract by @dilushiwijay.bsky.social & @priti899.bsky.social

𝗜𝗦𝗡 𝗩𝗜𝗗𝗘𝗢 𝗔𝗕𝗦𝗧𝗥𝗔𝗖𝗧 𝗦𝗘𝗥𝗜𝗘𝗦: Efficacy & safety of pegcetacoplan in kidney transplant recipients w/recurrent C3G or primary IC-MPGN: 12-week results: NOBLE study. 2025 @kireports.bsky.social www.kireports.org/ar... #VideoAbstract by @dilushiwijay.bsky.social & Divya Bajpai

A glimpse at the causes of an Acquired Bartter Defect too! #ECNeph @myadla.bsky.social @dramiliflores.bsky.social @dilushiwijay.bsky.social @kajareeg.bsky.social @theisn.org @nephroseeker.medsky.social

❓ What is this Acute Pseudo colonic Obstruction (Ogilvie’s syndrome)? 👉 Several theories have been proposed @myadla.bsky.social @dramiliflores.bsky.social @dilushiwijay.bsky.social @kajareeg.bsky.social @theisn.org @nephroseeker.medsky.social #ECNeph

👉 In vitro studies suggest that colonic Maxi – K channels are upregulated 👉 These are the same channels upregulated in CKD, enhancing gut excretion of potassium 👉 In ESRD, the colonic excretion of Potassium is 3-fold that of normal individuals #ECNeph @myadla.bsky.social @dramiliflores.bsky.social

Here are some of the case reports describing hypokalemia in Ogilvie’s syndrome @myadla.bsky.social @dramiliflores.bsky.social @dilushiwijay.bsky.social @kajareeg.bsky.social @theisn.org @nephroseeker.medsky.social #ECNeph

Here’s an infographic describing the various mechanisms of hypokalemia Highlighted in brown = Present in this case Shout out to @dana_m_larsen , my Nephrologist colleague from UCSF for the amazing infographic #ECNeph @myadla.bsky.social @dramiliflores.bsky.social @dilushiwijay.bsky.social

Have we done urine electrolytes ? #ECNeph

7/n Could this be driven by an inflammatory or infectious process? Time to think about the broader approach—and consider the possibilities. #ECNeph @dakidneydoc.bsky.social @dramiliflores.bsky.social @myadla.bsky.social @dilushiwijay.bsky.social pubmed.ncbi.nlm.nih....

1/n 🚨#ECNeph returns! Time to meet our next patient... A 50-year-old lady walks into your nephrology radar. What would you be looking for next? Clues ahead… 👀🔍 #ECNeph @dakidneydoc.bsky.social @dramiliflores.bsky.social @myadla.bsky.social @dilushiwijay.bsky.social

Hi Im Dilushi, nephrologist form Colombo.. first time joining #ECNeph on bluesky! No COI

⏰ Just 2 hours before #ECNeph! 🔍What is hypokalemia for nephrologists? Is it really a diagnostic puzzle 💥 Let’s connect the dots live in today’s case discussion! #NephSky #MedSky @dakidneydoc.bsky.social @dramiliflores.bsky.social @dilushiwijay.bsky.social @kajareeg.bsky.social @theisn.org

Limited understanding of CKDU, scarce resources, and weak infrastructure hinder comprehensive care for affected populations. @dilushiwijay.bsky.social, Senior Lecturer, University of Colombo, Sri Lanka. Stay tuned for the Policy Forum Pamphlet! 🔗 http://lite.spr.ly/6...

“The CPC Forum: Navigating Dilemmas in Modern-Day Nephrology Practice” Join us for this interesting exploration of the traditional CPC format where deductive reasoning meets modern diagnostic tools! 🔬🧬📝🔍 🏥: KEM Hospital, Mumbai 🗓️: 26th April, 2025 ⏰: 9.30 am - 5.00 pm forms.gle/2rrzSY7E3NTi...

18/n #ECNeph @drsumanbehera.bsky.social @myadla.bsky.social @drpriyajohn.bsky.social @theisn.org Diversity of Kidney involvement in Neuroendocrine tumors !

19/n #ECNeph @drsumanbehera.bsky.social @myadla.bsky.social @drpriyajohn.bsky.social @theisn.org Check this informative slide on tubular involvement in CgAN

17/n #ECNeph @DrSumanBehera.bsky.social @myadla.bsky.social @drpriyajohn.bsky.social @theisn.org Lets check this wonderful infographic on - Approach to intratubular casts !

17b/n #ECNeph @drsumanbehera.bsky.social @myadla.bsky.social @drpriyajohn.bsky.social @theisn.org Here is some more info about CgA....

Have any of you encounter Chromogranin A (CgA) Nephropathy/Tubulopathy? Not sure how to add a poll on BSKY!🤔 #ECNeph #ISNEducation #MedEd #Nephrology @myadla.bsky.social @drpriyajohn.bsky.social @drmarthagulati.bsky.social @dilushiwijay.bsky.social l @theisn.org @arvindcanchi.bsky.social

🗜️What is #ChromograninA ? ☠️HOW DOES IT ACT? ➡️ cytokines, degranulation, apoptosis... Lots of inflammatory processes⚡️ #ECNeph #ISNEducation #MedEd #Nephrology @myadla.bsky.social‬ @drpriyajohn.bsky.social @dilushiwijay.bsky.social @theisn.org @arvindcanchi.bsky.social

#ECNeph #CgATubulopathy #CgANephropathy ➡️ Acute Tubular Injury. 🗜️#chromograninA expands/swells and collects within #ProximalTubules 🏗️ #CgA forms intraluminal #tubular #casts @myadla.bsky.social‬ @drpriyajohn.bsky.social @dilushiwijay.bsky.social @theisn.org @arvindcanchi.bsky.social

17/n #ECNeph @drsumanbehera.bsky.social @myadla.bsky.social @theisn.org Spectrum of AKI in patients with cancer ! Clinical Journal of the American Society of Nephrology17(9):1385-1398, September 2022.