“The kidneys make the stuff of philosophy itself.” ♥️ Thank you @msocomd.bsky.social

👉Before we start, a few reminders! Are you new to #NephJC ? Not sure what to do or how this works? Here is a quick rundown, an infographic made by Sinead Stoneman#NephJC

⏰90 minutes left until #NephJC chat Hemoglobin targets have swung widely: 📈 Normalize Hb → CV harm signal 📉 Conservative targets → persistent symptoms Have we found the sweet spot yet?

⏰2 hours until #NephJC chat Anemia in CKD has shaped nephrology for decades ESAs, iron, transfusions, now HIF-PHIs But one question remains: 👉 Are we treating anemia optimally or cautiously?

#NephSky #MedSky 🩸Blood is thicker than water 🌊 Thankfully we thinned out the 2026 KDIGO Anemia Guidelines for you to peruse. Come discuss what's new. Tuesday 2/24/26 at 9pm EST on Bluesky! Summary by @jeyakumarmeyyappan.bsky.social www.nephjc.com/news/kdigo-anemia

Anemia research in CKD has had so much big fraud stories (which we don’t touch in the #NephJC write up) given the $$$ - the Normal Hct shady analysis from Amgen and PIs that @nejm.org allowed and still stays there - the Roxadustat p-hacking that brought down Fibrogen and tainted HIF-PHIs

Marc Soco, nephrologist from the Philippines and flozinator, looking forward to the discussion. No COI #NephJC

nice (and free) review of genetic testing and counselling in renal disease journals.lww.com/kidney360/fu... in @asnpublications.bsky.social #Kidney360 #NephSky #Genetics

In patients with CV disease, the “normal” range may be misleading Mortality is actually higher at K⁺ 3.5–4.0 mmol/L while high-normal levels (4.5–5.0) are associated with lower mortality 👀 #NephJC pubmed.ncbi.nlm.nih....

Hey everyone! Marc here, joining from the Philippines. No COI #NephJC

🍌🥑Can pushing K⁺ to the high-normal range reduce ICD shocks and hospitalizations? 🎨 #Visualabstract by @jeyakumarmeyyappan.bsky.social ⏰ #NephJC chat on Jan 27, 9 pm EST www.nephjc.com/news/2026/1/...

¿Elevar el K⁺ al rango alto-normal puede reducir las descargas del DAI y las hospitalizaciones? 🎨Resumen visual por @jeyakumarmeyyappan.bsky.social ✍️Traducido por @dramiliflores.bsky.social www.nephjc.com/news/2026/1/...

Oh, the weather outside is frightful 🥶🥶 But #NephJC is so delightful, and since you've no place to go #NephSky... Come discuss POTCAST: potassium goals and cardiac arrhythmias 1/27/26 at 9pm EST on #Bluesky Summary by @shelliefravel.bsky.social @salinesolut.bsky.social www.nephjc.com/news/potcast

It's 2026!🎉 We will be counting down the Top Ten Nephrology Stories of 2025 on 1/6/26 at 9 pm EST. Join us on TWITTER (it will always be Twitter to us). Come on by #NephJC faithful for a lively discussion! You picked & we're count'em down. www.nephjc.com/news/2025/1/3/top-stories-in-nephrology-2025

1/10 Last #NephJC we discussed dialysis frequency in AKI-D #TenPostNephJC We sought to answer an age-old question: Is less is really more? Or less is just simply what it is….less? pubmed.ncbi.nlm.nih.gov/41201895/

Have you ever “withheld” dialysis because the patient looked good despite questionable labs? Did you feel brave or nervous? 😅 We restrict fluids, potassium, phosphorus… But what about restricting dialysis itself? Let’s talk. #NephJC

Hi everyone ! Marc here from the Philippines 🇵🇭 sharing this “imprisonment” from Jerónimos Monastery in Lisbon 🇵🇹. From historic monasteries to modern trials, let’s LIBERATE-D our thinking. Looking forward to a great discussion! No COI. #NephJC

Gracias! @dramiliflores.bsky.social #NephSky LIBERATE-D: El Resumen Visual — #NephJC www.nephjc.com/news/2025/12/14/liberate-d-el-resumen-visual

www.nephjc.com/news/... Check out the excellent #NephJC summary by @msocomd.bsky.social and @sejalplakhani.bsky.social

Join us for the last #NephJC of 2025, 12/16/25 at 9pm EST!🥳 How soon should we withhold dialysis in AKI? We're discussing the LIBERATE-D trial #NephSky This one might just change your mind 🧠🧠 Blog by @msocomd.bsky.social and @sejalplakhani.bsky.social www.nephjc.com/news/liberated-aki

Holy Mackerel! 🐟 🦜Ahoy matey! Could fish oil unlock the mysteries of increased CV mortality in ESRD? 🏴‍☠️ #NephJC Join us for a lively trawling trip 12/2/25 🛥️at 9pm EST Check out the PISCES VA by @brianrifkin.bsky.social www.nephjc.com/news/piscesva

1/10 Last #NephJC we discussed the ORIGIN 3 trial which investigated the use of Atacicept in IgAN #TenPostNephJC Read the article 👇 www.nejm.org/doi/10....#NephJC

T4d: That’s all partners 🤠 From here until the end of the year we will be catching up on all the late-breaking and simultaneous publications from #KidneyWk 2025. 😮‍💨 Ain’t no party like a #NephJC party!

T4c: #NephJC The rapid development of treatments for IgAN shows that nephrology can innovate like oncology and cardiology, to the benefit of our patients. Some final words of wisdom from #KidneyWk 2025

T4a: #NephJC We recently got to hear the patient voice from @jonathanpollack.bsk.social About his journey with IgAN and his excitement for a future of precision medicine while also calling for greater worldwide equity.

T3c: #NephJC The emerging evidence from APRIL/BAFF–axis trials (including VISIONARY (sibeprenlimab) & ORIGIN-3 (atacicept)) highlight how central this pathway is to the mechanisms of IgAN.

Sorry will remain a dream for a while! We may have network meta-analysis - or will have to wait for them to go generic for an NIH (if NIH will even exist) or some other public funding body to do those trials #NephJC

Same here in 🇨🇦! Related paper: jamanetwork.com/journals/jam... in @jamainternalmed.com Often RCTs include patients in our countries - but the pharma doesn’t bother with getting drugs approved outside the lucrative US market #NephJC

Hi everyone, Marc from the Philippines. Exciting times for IgAN… so much happening so fast! And the ASN FOMO is definitely real this year. No COI. #NephJC

⏰ 2 hours until chat tonight #NephJC editorial team debated for a long time...not whether to discuss @kdigo.org IgAN guidelines, but whether to do it after #Kidneywk...Have we said it well: IgAN guidelines: fresh out of press, already aging gracefully? 👀See it for yourself

Check out the awesome visual abstract by @salinesolut.bsky.social Attacking the origins of IgAN with atacicept ⚔️ www.nephjc.com/news/2025/11/17/origin-3-the-visual-abstract

Resuman Visual Revisa el resumen visual realizado por Clemens Weber @salinesolut.bsky.social . Gracias @dramiliflores.bsky.social ! www.nephjc.com/news/2025/11/17/origin-3-el-resumen-visual

Tonite 11/18/25 on #Bluesky 9pm EST We are discussing ORIGIN3 and atacicept in IgAN. APRIL, BAFF and B-cells, Oh My! (🦁🐯🐻) It's going to be Wicked good. 🧙‍♀️ #NephJC Summary by @notjustdialysis.bsky.social www.nephjc.com/news/atacicept-origin3-gtfb36

We had a lot of discussion with Barratt at his rounds on this. His point is that - early diagnosis/identification early in disease process will be key - we do have specific treatment options available now (or will soon have) - just RASi and Flozins without biopsy just masks the issue #NephJC

🎨Beautiful visual abstract by Dr Natalia Nombera @roxnonna23.bsky.social #NephJC www.nephjc.com/news/...

Hey everyone, Marc from the Philippines. Looking forward to learning tonight. No COI #NephJC

🔬for the diagnosis of glowmrulonephritis, searching for urinary acanthocytes only using bright field illumination is clearly suboptimal compared to utilizing dark field illumination or phase contrast microscopy. #UrinarySediment #UrineMicroscopy karger.com/gdz/article/...

⏩ Next #NephJC is on IgA nephropathy @kdigo.org guideline 🎨 Nice visual summary by @roxnonna23.bsky.social www.nephjc.com/news/2025/10...

Obinituzumab aka ‘Obi’ is now FDA approved for lupus nephritis finance.yahoo.com/news/fda-app... #lupus

No one should I remember being mobbed by dietitians in Argentina who are believers in this costly approach (after #ISNWCN debate) Outdated therapy. Move on and flozinate instead #NephJC

Here’s @kidneyboy.bsky.social take on that study pbfluids.com/2009/02/jour... #NephJC

🎨Beautiful visual abstract by @msocomd.bsky.social #NephJC

Check the insightful #NephJC summary by @shelliefravel.bsky.social

Hi everyone, Marc here. Looking forward to hearing everyone’s insights. No COI. #NephJC

Check at the VA for our discussion of protein diet strategies by @msocomd.bsky.social. Is restricting protein in CKD and pushing protein in ESRD #TWDFNR? www.nephjc.com/news/2025/10...

It's that time of year again 🍂🍂🍂 The #NephJC Fall pledge drive. Plese give if you are able to support our decades long mission of #FOAMed for all. #NephSky #MedSky www.nephjc.com/news/2025/9/22/nephjc-fall-pledge-drive

1/10 Welcome to #TenPostNephJC Last #NephJC we discussed about AHA/ACC 2025 Hypertension guidelines: PREVENT, Detect, Treat Didn’t catch the pulse of this one? No worries we’ll help you pressure check the 2025 AHA Hypertension Guidelines. ❤ #AHA2025 www.ahajournals.org/doi/10.1161/...

Right: more aldo, more combo meds, advocating for GLP1 as part of lifestyle change Wrong: 130=/=120, even stronger aldo rec, even stronger GLP1 rec so that insurance will cover it #nephjc

www.nejm.org/doi/full/10.... There’s some trial data on prevention of albuminuria #nephjc