www.science.org/doi/10.1126/... related to frog in boiling water and #nokings

ICE Boasts Zero Murders Committed By 5-Year-Olds Since Child Detainments Began

Strong statement today from UC's Academic Senate:

IF ANY CALIFORNIA UNIVERSITY SIGNS THIS RADICAL AGREEMENT, THEY'LL LOSE BILLIONS IN STATE FUNDING — INCLUDING CAL GRANTS — INSTANTLY. CALIFORNIA WILL NOT BANKROLL SCHOOLS THAT SELL OUT THEIR STUDENTS, PROFESSORS, RESEARCHERS, AND SURRENDER ACADEMIC FREEDOM.

New week, new tool: Find our Protein Domain Designer tool to generate publication-ready protein domain diagrams here: domaindesigner.farnunglab.com

ICE Argues Migrants In Camps Are Free To Die At Any Time https://theonion.com/ice-argues-migrants-in-camps-are-free-to-die-at-any-tim-1835623878/

RFK Jr. Promotes Natural Immunity With Invitation To Touch His Festering Sore

"Did I remove track changes?"

CRISPR is amazing

How every PhD project develops

I am thrilled to share a joint work with Melissa Gymrek that spans several years to study what is the impact of promoter proximal short tandem repeats (STRs) on expression by using MPRAs. I am sure you'd enjoy! Awesome effort by @xzhangbsky.bsky.social and the team! www.biorxiv.org/content/10.1...

First Colbert, now Kimmel. Last-minute settlements, secret side deals, multi-billion dollar mergers pending Donald Trump's approval. Trump silencing free speech stifles our democracy. It sure looks like giant media companies are enabling his authoritarianism.

WGA Statement on ABC’s Decision to Pull Jimmy Kimmel Live!

Doomscrolling pause to chat CRISPR libraries! Preprint describes our new, data-driven approach to combine on-target and off-target predictions much more intelligently for *selecting* guides, which we use to develop our newest Cas9 knockout library, Jacquere. Thread: www.biorxiv.org/content/10.1...

I'm excited to share the terrific work by my graduate student Yuwei Cao - the development and use of spa-ChIP-seq, a fully automated ChIP-seq protocol (1/3)

Hey Australian genetics/genomics friends: the OurDNA Symposium will be in Sydney on 14 August, just before the HGSA meeting. Learn more about inclusive recruitment for genomics and get a preview of the OurDNA variant browser! events.humanitix.com/ourdna-sympo...

A Direct Hit, by @holdenthorp.bsky.social @science.org www.science.org/doi/full/10.... "This is a moment to unite."

Mitch McConnell Vows To Continue Falling Down Stairs In Face Of Fascist Takeover theonion.com/mitch-m...

Science is absolutely key to the US's success but this government's intention to now dramatically reduce the part of the federal grants that go to the university (in addition to the researchers; the "indirects") is like removing the unseen roots of a tree and expecting it to continue to flourish.

Me: if you’re going to argue about it, we’ll have a shower every day. 10yo: so if I take a shower everyday that means I can be annoying and argue about it. Me:

Please repost! We’re trying hard to sort out rumors from truth + would like to hear from anyone affected by the new federal orders + NIH pause. Patients, scientists, health equity researchers: please contact us below. We won’t share anything without your permission. www.statnews.com/2025/01/25/t...

Brilliant

“A state of panic” - yeah, that sounds about right. The “standard” budget cuts and restrictions all these agencies see every year are bad enough. Putting public health in the hands of Mr. Whale Goo gives me the screaming skeeves. 🧪

"Ashley Jardina distinguishes between a politics of racism and white identity. Some white voters who are not opposed to stronger social-welfare policies in general can be manipulated by appeals to the sense that white people as a group are threatened." www.theatlantic.com/politics/arc...

VOTE

@itaiyanai.bsky.social started a thread on twitter and I thought of bringing it here as well

Trump: I’ll probably agree to the ABC debate (He already agreed to the ABC debate)

Trump actual speech vs. What WaPo put into article.

Ladies and gentleman and vastly more interesting genders: we got him. We finally caught Schrodinger's cat.

No, Goddamnit, WashPost, it's not on her. It's on him and you. She faces nothing but racism and misogyny. You, as editors, face the test of how you will deal with that. You fail.

President Biden called for sweeping changes to the Supreme Court, including a constitutional amendment that would limit immunity for presidents, impose term limits for justices, and stipulate an enforceable code of ethics. What do you think? www.theonion.com/biden-calls-...

Two WaPo headlines. I don’t know how to write about politics but I’ll say this.: I’m an American and I’ve lived in Venezuela. I don’t think my countrymen really have a handle on just how incredibly easy it is to get from one headline to the other.

can't believe we're in a world that's gone from "how the fuck do I stop Dems from texting me" to "please inject Dem press releases straight into my veins"

Yup. It's okay to stop pretending he doesn't mean what he says, and that his party pals won't do their damnedest to make it happen.

“…and generally sounded like someone you wouldn’t want to sit near at a restaurant – let alone be President of the United States.”

President Venn Diagram xkcd.com/2962

My latest cartoon for New Scientist

Our review article, with Ira Deveson, @hdashnow.bsky.social, @dgmacarthur.bsky.social, on sequencing & characterising short tandem repeats is out in @NatRevGen! We delve into short read & long read STR genotyping tools and applications in rare disease & population genetics 🧬go.nature.com/48pWZix