Now that our Nature Genetics paper is out, here’s a “Behind the Paper” post on how colorectal cancers outsmart the immune system from the beginning. 👉 communities.springernature.com/posts/when-c... @eszterlakatos.bsky.social @trevorgraham.bsky.social #CancerResearch #Immunology #TME #Epigenetics

New @natgenet.nature.com paper from the brilliant @eszterlakatos.bsky.social presents evidence that chromatin alterations disrupt antigen presentation & neoantigens in colorectal cancer. Also that immune escape is part of the "Big Bang", at the outset of CRC growth. www.nature.com/articles/s41...

📢 EvoMG-DN PhD applications are now open! Join our EU-funded MSCA network and explore evolution, ageing, and disease. 👉 www.evomg-dn.eu 📅 Apply by 30 November 2025 #PhD #DoctoralTraining #MSCA #HorizonEurope #Genomics #EvolutionaryBiology #BiomedicalResearch#EarlyCareerResearchers

Check out how we tackled one of the fundamental challenges in immunology, out today @cp-cellsystems.bsky.social: www.cell.com/cell-systems.... Our major innovations are BATCAVE and BATMAN, two new players to get us closer to solving TCR-pMHC predictions!

Sleep when the baby sleeps, eat when the baby eats, edit your manuscript when the baby edits their manuscript

🏆 Honoured to receive the 2025 Inaugural BACR Early Career Award! Grateful to @thebacr.bsky.social and all who’ve supported me — esp. @trevorgraham.bsky.social, @eszterlakatos.bsky.social & @cancerresearchuk.org 💙 Reflections→ www.bacr.org.uk/news/2025-in... #CancerResearch #EarlyCareer #ScienceWins

Very cool story and especially useful mathematical models for everyone to use! Check it out!!!

As much as it's a meaningless milestone, the mathematician in me is happy to see exactly 2^10 citations on the one random day I decide to finally visit my own Google Scholar :)

🚨With some delay, we're excited to announce that our proposal for a MSCA Doctoral Network on Evolutionary Medical Genomics (EvoMG-DN) got funded! 🎉 🧬 14 labs and 2 companies across 7 European countries will be coordinated by the EvoMG Joint Program at @crg.eu & @upf.edu. europa.eu/!NNq63m

Happy to share details of this meeting and the exciting line-up of speakers. Hope to see you there. Please re-post www.crick.ac.uk/whats-on/5th...

Tour de force from @melissabarroux.bsky.social on evolutionary and microenvironmental dynamics of oesophageal adenocarcinoma through neoadjuvant therapy Published @natcancer.nature.com Melissa is an outstanding new clinician scientist.. one to watch. www.nature.com/articles/s43... @icr.ac.uk

📣Open PhD position in Machine Learning at Uppsala University. Focus: Bayesian mathematical models and methods for biomedicine.

Can we use the power of evolution to improve ovarian cancer treatment? Our latest paper says yes! Online now at Cancer Research. Thanks to @trevorgraham.bsky.social coauthors and @cancerresearchuk.org for funding.

📰 Can we use the power of evolution to improve ovarian cancer survival? A surprising approach called adaptive therapy holds promise, according to findings by @mlockley.bsky.social & team at @qmul.ac.uk & @icr.ac.uk. Read more ➡️ www.bci.qmul.ac.uk/general-news... #AACR25 #medsky #oncosky🧪

If you're a PhD student interested in using maths to understand cancer, this HCEMM summer school in Szeged, Hungary, is an excellent opportunity. Registration is free and local costs are covered, so apply before 15th April.

Our #Cancer #Evolution summer school runs again 30 June-3 July at the beautiful Genome Campus in Hinxton, UK sponsored by @wellcometrust.bsky.social Ideal for starters in the field; this year's focus is on using genomic data for cancer evo research. Brilliant & inspiring faculty! bit.ly/40nLdDD

We have an opening in our #DataScience core @icr.ac.uk. The post will work on a breadth of topics across #cancer biology, but expertise in spatial data, single cell and data integration are priorities. Details here: jobs.icr.ac.uk/vacancies/11... @jobrxiv.bsky.social

Come work at the European Molecular Biology Laboratory in the beautiful science & university city Heidelberg as a Research Software Engineer on R/Bioconductor tools for biological data science and AI ! embl.wd103.myworkdayjobs.com/EMBL/job/Hei...

Delighted our work using aneuploidy as a biomarker of colorectal cancer risk in inflammatory bowel disease is out: gut.bmj.com/content/earl... The initial reaction from patients&families has been overwhelming Led by Ibrahim AlBakir @yosoykit.bsky.social @cancerresearchuk.org @icrlondon.bsky.social

Applications for this "Black Leaders in Cancer" #PhD studentship with our lab @icrlondon.bsky.social close on Thursday... if you know of someone who might be interested please do pass the link on.

Excited to share our perspective on genetic immune escape alterations and their impact on tumor evolution, metastasis, immunotherapy, and interactions with tumor-extrinsic factors. It was a pleasure collaborating with Diego on this -hope you enjoy the read!☺️ www.sciencedirect.com/science/arti...

Our paper on chromosomal abnormalities in normal breast tissue from BRCA carriers came out last week. www.nature.com/articles/s41...

Calling all systems and computational biologists in search of a faculty position: We have Assistant and Associate Professor positions! 🚀 Pittsburgh is beautiful, and we are doing amazing science here. cfopitt.taleo.net/careersectio... cfopitt.taleo.net/careersectio... Please apply by Dec 2!

Reminder for newcomers that bioRxiv has Bluesky accounts in every subject category - great way to keep up (please re-skeet) connect.biorxiv.org/news/2023/09...

We have an open #PhD #studentship as part of our "Black Leaders in Cancer" programme at @crukconvergence.bsky.social & @icrlondon.bsky.social. About computational modelling of T-cell evolution in cancer. www.findaphd.com/phds/project... I'm looking forward to meeting prospective students #CRUKfunded

I suppose now is a good time to introduce #BiologyInNumbers, a #SciComm podcast I have the pleasure of directing, producing & hosting. Thought up by then-President Heiko Enderling, it's a means to learn about @smbmathbiology.bsky.social and research from its members and the wider #mathBio community.

Couldn't wish for a better BlueSky debut post: Our spatial atlas of the developing thymus is now published in Nature! 🥳 www.nature.com/articles/s41... Also check out the other papers in the new Human Cell Atlas collection: www.nature.com/collections/... #singlecell #spatial #multiomics

Join us in Durham for a fully-funded multidisciplinary PhD studying Metals, Microbes, Maths, and Metabolism! Please pass this along to interested candidates who are welcome to contact us directly. Both theoretical and/or experimental backgrounds welcome! iapetus2.ac.uk/studentships...

We just published a review of lessons farmers have learned for how to control pesticide resistance from evolving, and how to apply those to oncology to prevent cancers from evolving therapeutic resistance: bit.ly/48OfFdX

Can colleagues amplify this appeal to journals and journal editors to open accounts on Bluesky, please? @MicrobioSoc @TrendsMicrobiol @CellCellPress @JBacteriology @jbiolchem @Nature @ScienceMagazine @PNASNews @MolMicroEditors @NAR_Open @NatureMicrobiol @NatureComms @ASMicrobiology 🙏 🦠🧪🧫🧬

Still 3 more weeks to apply for a PhD in computational biology/ cancer evolution! If you want to find out more about the many exciting positions in our department, we're doing a hybrid informal intro tomorrow: www.chalmers.se/en/current/c... (Non-Göteborg people can join on Zoom!)

We are looking for two enthusisastic scientists to join our work on the evolution of ecDNAs in human cancers. Become part of the great @CancerGrand and join our team eDyNAmiC family. Happy to chat any time. Please contact me and ask for details! www.qmul.ac.uk/jobs/vacanci...

Happy 2024 everyone! If your new year's resolution is to find a PhD (or help someone find a PhD) in computational biology, I've got just the thing 😉:

❣️I am looking for a motivated PhD candidate to join me in creating new methods for unraveling cancer evolution @chalmersuniv❣️ Exciting research (if I may say so), great work atmosphere and superb employment benefits❗️ Find out more and spread the word: www.chalmers.se/en/about-cha...