Today we had a great EvoMG Seminar by Dario Valenzano @dvalenzano.bsky.social from FLI, who told us about some of their recent aging work using the fascinating short-lived killifish. Hosted by @mirimiam.bsky.social evomedgenomics.com/events/exter...

1. Map evolutionary diversity to hack biomedical innovation 2. Revolutionize cancer therapy 3. Target the development of antimicrobial resistance 4. Address Anthropocene-related diseases 5. Support healthier behaviors 6. Improve pandemic responses by Barbara Natterson-Horowitz & Dan Blumstein!

“Although drug resistance closes some doors, it can open new ones.” In exciting research, our scientists have found that a recently discovered vulnerability in soft tissue sarcomas could pave the way for smarter, more adaptive treatment strategies that extend and save more lives.

Are you looking for a PhD? Join us in Barcelona! You'll dive into a community of >100 PhD students from 30 countries exploring the frontiers of biology. You can also join an online workshop on 6 November (15:00 CET) to learn how to find the right lab for you. More info: www.crg.eu/en/content/t...

#PhDOffer #AcademicJobs #PhDChat #PhDLife 📣 15 fully funded PhD positions in Evolutionary Medical Genomics (@evomg-bcn.bsky.social) are open! 🧬🔬 Explore ageing, cancer evolution, and pathogen resistance across leading European institutions. Deadline: Nov 30 Apply here: www.evomg-dn.eu

Become part of a Marie Skłodowska-Curie Doctoral Network a prestigious EU initiative offering world-class research training, international experience, and strong career prospects for early-stage researchers. It’s more than a PhD:it’s a launchpad for your research career! Apply now: www.evomg-dn.eu

Including one position in our lab to work on emerging fungal pathogens. 👇 #phD #Candida

At the @melisupf.bsky.social, @mirimiam.bsky.social would like to recruit two fully-funded #PhDcandidate for the #MSCA Doctoral Network @evomg-dn.bsky.social. #AcademicSky #ResearchJobs

🚨🚨🚨 Two super well-funded PhD grants from our MSCA Doctoral Network @evomg-dn.bsky.social at our lab at @melisupf.bsky.social, @crg.eu and the @evomg-bcn.bsky.social Program. If you're excited about evolution, genomics and biomedical research, this is your DN! 😃 Further info: www.evomg-dn.eu and 👇

We’re proud to introduce the Principal Investigators leading the EvoMG Doctoral Network, an international team guiding and mentoring the next generation of evolutionary medicine researchers. Discover more about their work and the PhD opportunities 👇 www.evomg-dn.eu

📢 EvoMG-DN PhD applications are now open! Join our EU-funded MSCA network and explore evolution, ageing, and disease. 👉 www.evomg-dn.eu 📅 Apply by 30 November 2025 #PhD #DoctoralTraining #MSCA #HorizonEurope #Genomics #EvolutionaryBiology #BiomedicalResearch#EarlyCareerResearchers

The second is about potential fitness costs of cancer drug resistance, and how we might exploit them using approaches like adaptive therapy. (building on our work with @mlockley.bsky.social in ovarian cancer: aacrjournals.org/cancerres/ar...). Description here: www.icr.ac.uk/study-and-ca...

We have two fantastically well-funded #PhD studentships available through the @evomg-dn.bsky.social #EU doctoral network (led by brilliant @mirimiam.bsky.social, @crg.eu). These enable students to move to the UK and come and work with us @icr.ac.uk to exploit #cancer #evolution for patient benefit.

Las week, the @prbb.org hosted the Iberian EvoMG PI Meeting 2025. An event organized by the @evomg-bcn.bsky.social & @biomics-twinning.bsky.social to bring together all researchers working on the different areas of evolutionary medical genomics. Delighted to see so many familiar faces there! 🙌😊

And the last session of the meeting was Session 5: Cancer. The first speaker was David Posada ( @davidposada.bsky.social ), from the Universidade de Vigo and @cinbio.bsky.social, who showed us how somatic phylogenetics can provide fundamental insights into the evolutionary dynamics of cancer.

In between Sessions 4 (aging) and 5 (cancer), we had the perfect bridge between the two topics, with the second keynote talk, by Iñigo Martincorena (@imartincorena.bsky.social), who told us about their work on somatic evolution, and its implications for aging and cancer.

The last day (Fri 10/10) started with Session 4: Aging and related diseases.

And after the round table, we continued Session 3 on microbes, microbiome and antibiotic resistance, with Maria Isabel Veiga, from @icvs-uminho.bsky.social , who talked about drug resistance in malaria.

After the coffee break, we had a round table about dealing with evolution of drug resistance & synergies among EvoMG fields. We had a panel representing the different related "areas": Isabel Veiga (Plasmodium), David Posada (Cancer), Jero Rodriguez (Bacteria), Ana Abecasis (Virus).

Session 3 (Thr 09/10 in the afternoon) was dedicated to Microbes, microbiome and antibiotic resistance.

After the lunch break, Teresa M. Coque (@tmcoque.bsky.social), from the Hospital Universitario Ramón y Cajal (IRYCIS) gave us a special talk with her EvoMG view from the hospital. A historical and conceptual perspective on disease evolution and its co-evolution with society's ways to tackle it.

After the coffee break, we continued with the Session 2b: Genomic basis & history of disease. The first speaker was Sandra Acosta ( @sacostav.bsky.social ), also from @ub.edu, who told us about her work inferring the role of conserved regulatory elements in human brain development & disease

The second session (Thr 09/10, morning) was dedicated to the Genomic Basis & History of Disease.

The first session of the Iberian EvoMG PI meeting was on "Virus, transposable elements & biotechnology". 🦠🧬 The first speaker was Ana Abecasis from NOVA University of Lisbon, on HIV-1 transmission and evolution.

Opening keynote talk by Pedro Beltrão on the genetics of human trait variation across the scales of biological organization.

Nuno Morais kicking off the Iberian EvoMG PI meeting, organized by @evomg-bcn.bsky.social and @biomics-twinning.bsky.social at PRBB in Barcelona! evomedgenomics.com/events/iberi...

At EvoMG-DN we believe that evolutionary history shapes both the human genome and its pathogens and ultimately disease susceptibility. We will tackle health challenges from an evolutionary perspective in the topic of: ageing, cancer and infectious diseases. #PhD #EvolutionaryBiology #MSCA

Amazing talk by @elinork.bsky.social today at @prbb.org ! 🐶🦇🐪🦏 Hosted by @weghornlab.bsky.social

🚀 Exciting news: the Evolutionary Medical Genomics Doctoral Network (EVOMG-DN) launches soon! 🔍 15 fully funded PhD positions: ready to shape the future of genomic medicine? Stay tuned for details! #PhD #EvolutionaryBiology #MSCA #PhDPositions

New review from @chloecolson.bsky.social on cancer evolution & plasticity from a mathematical modelling lens: www.sciencedirect.com/science/arti... Chloe provides a framework to think about plasticity & evolution, & explains how maths models can reveal cell dynamics that we can't directly observe.

Happy to be the next (and 1st female) @crg.eu director. The CRG always stood out to me, for its excellence in understanding life's principles, with implications for health and biodiversity, & its collaborative, open and innovative way of doing science. Thrilled to join its amazing community in 2026!

Thrilled to become an EMBO Member! Thanks so much to @embo.org for the recognition, and thanks A LOT to all current and past lab members, mentors and collaborators for making it possible! 🤗

A study by @ibe-barcelona.bsky.social @uspoficial.bsky.social shows the great genetic diversity of Brazil and its implications for the health of the population. 🧬#DNAdoBrasil project has sequenced +2700 complete genomes and revealed +8M unknown genetic variants. ‪@hunemeier.bsky.social More info👇

New preprint in collaboration with @paulinanunezv.bsky.social supervised by @jonnyfrazer.bsky.social and Mafalda Dias – we propose a simple approach to improving zero-shot variant effect prediction in pre-existing protein and genome language models: 🧶 1/n www.biorxiv.org/content/10.1...

Scientists make breakthroughs on blood ageing and limb regrowth https://www.ft.com/content/a1f83886-fb29-4f5f-9577-bec61dfd31d2

🚨With some delay, we're excited to announce that our proposal for a MSCA Doctoral Network on Evolutionary Medical Genomics (EvoMG-DN) got funded! 🎉 🧬 14 labs and 2 companies across 7 European countries will be coordinated by the EvoMG Joint Program at @crg.eu & @upf.edu. europa.eu/!NNq63m

The essay by @awaisaftab.bsky.social does a fine job of describing how cliff-edge fitness functions may explain vulnerability to some diseases. For an accessible Psychology Today article on the topic, see the link below. www.researchgate.net/publication/...

APOBEC shapes tumor evolution and age at onset of lung cancer in smokers https://www.biorxiv.org/content/10.1101/2024.04.02.587805v1

Our #Cancer #Evolution summer school runs again 30 June-3 July at the beautiful Genome Campus in Hinxton, UK sponsored by @wellcometrust.bsky.social Ideal for starters in the field; this year's focus is on using genomic data for cancer evo research. Brilliant & inspiring faculty! bit.ly/40nLdDD

Peto's Paradox—that cancer does not increase with body size of mammals—was wrong. A new, comprehensive study of 263 species documents higher cancer prevalence with increasing body mass. Some large animals (e.g. elephants) have some built-in genetic adaptations www.pnas.org/doi/10.1073/... @pnas.org

The Abstract deadline is Feb 3 for the 10th annual meeting of the International Society for Evolution, Medicine, and Public Health in Nashville. All welcome, esp. students and clinicians. Full info at iemph.org Please repost #EvMed 🧪 @evmed.bsky.social @sse-evolution.bsky.social @eseb.bsky.social

So pleased to have the paper out, available here: www.nature.com/articles/s41586-024-08423-8 For me this was discovery science as I had always hoped it would be. A lot of fun, and some proper detective work with plenty of twists & turns on the way. Brief thread below

🌟NEW PREPRINT ALERT!🌟 We are very pleased to introduce #StrainDifferences: “Genetic background sets the trajectory of cancer evolution” www.biorxiv.org/content/10.1... 🧵[1/12]

**Clinical Cancer Genomics Conference** First of an annual recurring series. It will be a very important meeting for the advance of clinical implementation of cancer genomics. Proud to be part of it. March 20th-21st 2025 in Amsterdam. Registration open: www.ccg2025.eu #CCG2025

We’re recruiting a PhD student to use comparative omics to investigate why some viruses can efficiently infect both human and mosquito cells, but lead to different infection outcomes. Fully funded position by @evomg-bcn.bsky.social at our lab at UPF-CRG and the Diez lab. www.crg.eu/en/content/t...

Reposting this list of #cancer #evolution scientists, in case its useful for the many newcomers.

How fast do #viruses spread? This study from @sdellicour.bsky.social &co in @plosbiology.bsky.social compares dispersal metrics derived from viral epidemic genome data with real-life dispersal capacity, revealing discrepancies attributable to host/human-mediated movement plos.io/3VoeOex

“Si en el cáncer no tenemos en cuenta la teoría de la evolución, fracasaremos”. Entrevisté para @elpais.com a Nicholas McGranahan, que ha recibido este año el premio Blavatnik para jóvenes investigadores en Reino Unido. (cc. @irbbarcelona.bsky.social) elpais.com/salud-y-bien...

I've started a list of people working on #cancer #evolution. Many more to be added, so do let me know if that is you. Also if you would like to be removed. go.bsky.app/QuAF4Mo

#Recerca Equips científics del @crg.eu, la #UPFBarcelona i l'IBE (UPF- @csic.es) uneixen forces per explorar com l'evolució influeix en la malaltia en l’àmbit molecular, amb la creació del primer programa mundial de genòmica mèdica evolutiva: @evomg-bcn.bsky.social