I am very pleased to see our work, in which we describe a mutational hotspot at transcription start sites in the human germline, out: www.nature.com/articles/s41... Great work from @castellanoed.bsky.social, @vseplyarskiy.bsky.social, Miguel Cortés Guzmán and Clàudia Serrano Colomé!

Our paper on clonal expansions in Sperm is out in Nature www.nature.com/articles/s41... If you are interested in working at an intersection of Mendelian genomics/Population genetics/Clonal expansions +Cancer genetics/ and of course mutagenesis, please rich out about postdoc in my lab

🦠🧫👩‍⚕️ "Sin la microbiota no podríamos vivir, es esencial para nuestra salud". Puedes recuperar la charla completa con la investigadora y microbióloga @mireiavallesc.bsky.social, y la cirujana Lola de la Puerta en 👉 www.ondacero.es/programas/ju...

Very happy to announce our paper on mutational signatures caused by mismatch repair knockouts. We find SBS57 is driven by alignment errors in MMR-deficient cells, experimentally confirm the association of MMR with SBS1 & expose differences between in vitro and in vivo MMR loss: tinyurl.com/ycyprxme

Did you know that transcription start sites harbor a huge excess of germline variants? Turns out this is driven by (divergent) transcription, mitotic, but not meiotic(!), double-strand breaks and early mosaic variants. Read the full story here: www.biorxiv.org/content/10.1...

🐦 Calling all Early Birds! ​ ​ Hurry up and seize the opportunity to participate in the upcoming ESEB Congress, set in the vibrant city of Barcelona 🌟​ ​ 🎟️ Secure now your place at the best possible price 👉🏻 eseb2025.com/registration... ​ #ESEB2025 #Biology #Evolution #Genomics