And you may saye to yourselfe These are not my lone and level sandes And you may saye to yourselfe These are not my vast and trunklesse legges of stone

It always helps to be reminded: By the time you're finished converting that reference file you found on the server you could have just downloaded the correct format and already had your command running.

wait you’re telling me that this simple task I’ve been putting off for two weeks, that has tormented me like a two hour task, only took 30 seconds to complete? If only there were a valuable lesson I could learn from this. Ah well. Nevertheless.

I vibe coded today. I kinda liked it.

Goodbye Summer 2025, it's been emotional. youtu.be/lpIBsWM42PU?...

10X Genomics acquiring Scale Biosciences.

Vaya con dios, 3730.

"our results indicate that academia pays a price by focusing attention and resources on superstars" Nice to see this supported by data analysis, now. H/T: @cxdig.bsky.social www.nature.com/articles/s41...

Found out the free drinks fountain at work can also output straight club soda. Couple that with some lemon wedges and I AM HYDRATED AF RIGHT NOW.

Illumina to acquire Somalogic. www.illumina.com/company/news...

As hardware stabilizes, it's time to start performance tweaking on the Illumina NovaSeq X. Here are some of the highlights from the latest batch of rumors regarding the next control software iteration:

One of the best things in the world is a slice of ricotta cheesecake with a dollop of lemon curd. Or marmalade. Or both... Or just a dusting of powdered sugar. Some sliced strawberries. Maybe raspberries? Anyway, the point is ricotta cheesecake is awesome. That's all. Happy Monday!

Tariffs hit the $ILMN supply chain.

Happy Friday, everyone.

The vaccine against Shingles helps protect against dementia, results of a natural experiment, adding to prior evidence "implications are profound" New @nature.com www.nature.com/articles/d41... nature.com/articles/s41...

Wake up y'all, it's the 1st of tha month. www.youtube.com/watch?v=4j_c...

I am thrilled to be a part of this initiative to help keep science moving forward. If you have samples you can get them sequenced for free with Ultima Genomics: www.genengnews.com/topics/omics...

Trying a slightly new model (for us at least) of #openscience. With @ronanchaligne.bsky.social and @karolisk.bsky.social, we pitted 10x Genomics Chromium GEM-X against Illumina PIPseq V head-to-head to understand these two platforms for single-cell genomics. Some thoughts off the bleeding edge: /1

Has anyone tried miniaturizing ONT's native barcoding ligation prep? If so: how low did you go?

That thing where you think DOGE has screwed up NCBI BLAST but it was just your browser cache needing to be cleared

That thing where you're having a quiet Monday morning only to realize Mail is not syncing properly with the Exchange server...

I got my wish! Illumina is coming out with 1.5B 2x300 on the X. NOW 💯 of projects are on the X. Full conversion!

If you missed the Roche seminar, here's a PDF of the side deck: assets.roche.com/f/176343/x/f...

Illumina right now:

Roche's new box is gonna be RUO. sandiegomics.com/roche-has-en...

Excited for AGBT's 25th anniversary! 🎉 I’m honored to join this wrap-up panel —always a highlight with great insights & discussions on the latest in genomics. Looking forward to catching up with friends & seeing what’s next for genomics! #AGBT25 #Genomics www.linkedin.com/posts/charli...

Excited to be part of this panel once again! I am truly honored to join my genomics idols, Jasmine Plummer, Jessica Nordlund, and Charlie Johnson, as we analyze and discuss the highlights from #AGBT2025 @agbt . Looking forward to an engaging conversation! www.genengnews.com/multimedia/g...

What is Gen Z's favorite PCR plate type? Skrrrt-ed

🎵 Plasmid twice the size that it oughta be so it's probably A dimer 🎶

"The Service you do for others is the rent you pay for your room here on Earth." -🥊Ali

If we're gonna audit the government and freeze the NSF and damage science funding, could we also maybe audit all the failed military projects that cost us tens of thousands of DEI programs worth of losses per project? Can we audit the billions that go missing too? Audit the government...FULLY

Is Ultima Genomics the ultimate genomics solution? Cool to see the sequencers (they insist on calling them tools) and mirror-finish sequencing wafers in action.

Here's a blue sky question: Assuming you could get RNA-seq data back within 4 weeks at $100/sample, would you pay extra if you got data back within 1 week of submission? If 'Yes': what would your breakpoint be? $150/$200/"Shut up and take my money"?

Here's a blue sky question: Assuming you could get RNA-seq data back within 4 weeks at $100/sample, would you pay extra if you got data back within 1 week of submission? If 'Yes': what would your breakpoint be? $150/$200/"Shut up and take my money"?

Nice way to get your beak wet using immunoarrays for proteomics

Every PI should gift their phd students a @nanoporetech.com P2S starter pack before it goes from ~10k USD to 28k$ (January 29). What amazing research project would you do with 8 promethion flowcells? 🎁🧬🚀

Double trouble in OKC now.

You're Still alive Still alive Still alive Still alive Still alive Still alive www.youtube.com/watch?v=gxCJ...

As a tall person I cannot offer to reach something on a high shelf for a stranger, yet if they ask me I must oblige. This is the law of the giants

@albertvilella.bsky.social likes to repost things without attribution. This thread is just posts I and others made on the Aseq Discord channel. Next time you see him post something interesting, remember that he's just blindly parroting things he sees elsewhere to make himself look smart.

Yooooo, if you wanna get in on the Nanopore party get a P2 Solo starter pack before the price goes up 150% on Jan 25th. Current: $9,555 After Jan 25: $27,955 (FYI @AlbertVilella )

New Element low kit coming, 100M reads, 2x75, $680. Also price drops for 2x300 expected to make them well under ILMN 2x300 prices Other big announcements at JPM expected. (FYI, @AlbertVilella)

Want a silly & fun distraction for however long you need it? Boom, I gotcha covered. All the finished series (and special episodes) of Taskmaster. If it can’t make you laugh nothing can. youtube.com/playlist?lis...

Illumina 25B flowcells now available!

Oh, great. THAT guy just showed up.