AMaNITA: an end-to-end workflow for native tRNA nanopore sequencing data analysis https://www.biorxiv.org/content/10.64898/2026.06.16.732588v1

Thrilled to present our comparative study on the evolution of zygotic genome activation (ZGA)!! 🥚🧬 Amazing PhD work of @campobes.bsky.social together with @fedemantica.bsky.social and many collaborators! @melisupf.bsky.social @crg.eu. Thread below 1/15 www.biorxiv.org/content/10.6...

New preprint from @novoalab.bsky.social ! Which tRNAs are used by ribosomes during translation? We introduce tRIBO-seq, a nanopore method to sequence ribosome-associated tRNAs and track how the active tRNA pool changes across stress conditions. www.biorxiv.org/content/10.6... Thread 👇

Latest #CDlab paper on nanopore protein sequencing on @biorxivpreprint.bsky.social: www.biorxiv.org/cgi/content/... Here, Justas Ritmejeris, @xiuqichen.bsky.social, collaborator @albadalab.bsky.social and me developed a conjugation chemistry strategy for nanopore sequencing of natural peptides!

Awesome place to do a PhD with exciting labs, a truly supportive PhD community, and the most scenic morning views you can imagine! 🌅 10/10

End-to-end protein design in the browser through evedesign. Generate and interactively explore designs in 2D/3D and export them as codon-optimized DNA. The underlying open source framework (released soon) is build to easily add new methods, more on that soon. 🌐 evedesign.bio

Very excited to share our new paper on the influence of biological sex and smoking in the clonal landscape of normal human bladder, just published in Nature. A big thank you and congrats to all the authors, specially to @raquelbmi.bsky.social for all the shared efforts in this journey! ⬇️More info⬇️

Novoa Lab joined the PRBB Open Day 2025🔬🧬🌊 @prbb.org to share our passion for RNA research with the public. Thanks to everyone who came to explore science with us and thanks organisers for making this event possible! #PRBBOpenDay #OpenScience

The goal of a PhD is not to learn some facts or read a few papers or learn a bunch of techniques. The goal of a PhD is to learn independence, problem solving, how to finish things you start, resilience, & gain the ability to adapt & think creatively. Learning these things is hard.

Looks like private funders, HHMI,CZI etc., are not going to “save” US research. Europe is setting up mechanisms to attract US researchers & it may work. But, common, target junior talent, don’t shower money on superstars who will be flying professors & return to US when the science winter passes.

RNA N-glycosylation enables immune evasion and homeostatic efferocytosis by chemically caging acp3U. Excited to report this work lead by Vinnie @vinnieviruses.bsky.social and in collaboration with @vijayrathinam.bsky.social in @nature.com www.nature.com/articles/s41...

Systematic benchmarking of basecalling models for RNA modification detection with highly-multiplexed nanopore sequencing. #DirectRNAsequencing #DRS #RNAmodifications #Nanopore #Genomics #Bioinformatics #ModelBenchmarking #Basecalling @biorxivpreprint.bsky.social www.biorxiv.org/content/10.1...

🚨 New preprint alert 🚨 We systematically benchmarked @nanoporetech.com 's modification-aware basecalling models released for RNA on sets of in vitro and in vivo sequences and made some curious observations 🧬🔍. bit.ly/4lXqNul Follow along for a little recap (1/12)

Another epic Novoa Lab retreat in the books! A big thank you to everyone who made it such a success — from the science-packed discussions and hands-on workshops to the brainstorming, games, sunny pool sessions, and delicious BBQs. And special thanks to the organizers!⚘️ @evamarianovoa.bsky.social

Now online! Pseudouridine RNA avoids immune detection through impaired endolysosomal processing and TLR engagement

Endinsa’t en una vivència sensorial única que connecta ciència i art immersiu. “SEEING: Un ull i una caixa” arriba del 5 al 14 de juny al Centre Cívic Convent de Sant Agustí (Carrer del Comerç 36, Barcelona). www.crg.eu/en/event/see...

### PhD position alert ### Please repost! I'm excited to announce a new *PhD position* within our group. We are looking for a super-motivated candidate with a solid basis in wet- and dry-lab research. Apply now & make sure to include all docs! werkenbijprinsesmaximacentrum.nl/en/vacancy/p...

Check it out - amazing new work by @raflynn5.bsky.social and Kostas Tzelepis labs, discovery of a cell surface RNA/glycoRNA binding protein that is also a cancer antigen, new target for antibody therapy! www.nature.com/articles/s41...

This was a fun interview by #FelixSchmidtner of Austrian @derstandard.at - EB www.derstandard.at/story/300000...

How has native RNA sequencing contributed to epitranscriptomic research? This is one of the main questions we addressed in our recent review by @evamarianovoa.bsky.social and I now live in Molecular Cell #RNAsky #RNA #nanopore authors.elsevier.com/a/1kS2f3vVUP...

rRNA fingerprinting by Nanopore sequencing reveals cell type biosignatures. 🧪 #RNASky www.cell.com/molecular-ce...

Elegant work from the labmate #IvanMilenkovic showing that 'epitranscriptomic fingerprints' of highly modified rRNAs can classify tissues / dev. stages / cell types and even health/disease status! #notstatic www.cell.com/molecular-ce...

New paper from Eva Maria Novoa's lab, demonstrating how barcoded direct RNA reads can be demultiplexed on #nanopore github.com/novoalab/Seq... www.biorxiv.org/content/10.1...