Congratulations to @gloryanne.bsky.social and our radiology, oncology and immunology teams for pioneering fine needle aspiration of HCC to tailor immunotherapy. We show that intratumoral neutrophils may predict CPI resistance: www.sciencedirect.com/science/arti...

It was such fun to gather Maini lab with @pallettlab.bsky.social @tcellvaccineucl.bsky.social @adas1.bsky.social and Alan Zhuang's labs for our Secret Santa lunch before the holidays. What a great bunch of smiles- proud they consider themselves the #ExtendedMainiFamily 😀

We're delighted to see immunologists once again recognised by the #NobelPrize! 🏆 Warm congratulations to the winners - their contributions have been vital in shaping our understanding of the immune system. More here: www.immunology.org/news/british...

Our paper is out! Check out this beautiful story where we uncovered that the costimulatory molecule ICOS is detrimental for PD-1+ CD8 T cells. Sustained ICOS signaling reduces memory-like features of progenitor exhausted CD8 T cells in chronic viral infection and liver cancer.

Antigen-specific antibodies secreted by plasma cells are rapidly identified using microfluidics and fluorescence-activated cell sorting (FACS) go.nature.com/4dHLaHB rdcu.be/etg8W

1/ 🚨 Hot off the press in Nature Immunology: CD4⁺ T cells can license Kupffer cells to rescue dysfunctional CD8⁺ T cells in the liver. Hepatitis B virus (HBV) infection is just the proving ground—this is a paradigm shift in tissue immunity. www.nature.com/articles/s41... 🧵(1/11)

Don’t miss this great scientific meeting and HBV family reunion

This will be an interesting project and great new lab-check out this post-doc position with our colleague Doug Fink @IIT UCL

We are very proud to bring you a highly requested new type of event this year 🙌: an ECR Careers Meeting 🤩 Join us Thurs. 13th March at the UCL IIT/Pears Building (Hampstead, London) 🚨Registration is FREE! Follow this link to register NOW! www.immunology.org/events/bsi-l... For more details👇

Nature research paper: Human-correlated genetic models identify precision therapy for liver cancer https://go.nature.com/41qNkbs

#hiring #postdoc We are looking for a postdoc to work on anti-tumor gamma delta T cells in breast cancer metastasis mouse models. Apply here: www.gla.ac.uk/explore/jobs...

Don’t forget to apply by 18th Feb for our 3 year Wellcome post-doc to join our great team working on HBV tissue immunity! www.linkedin.com/jobs/view/re...

Many of the extended 4th floor IIT family went out to celebrate Chinese New Year #YearOfTheSnake 🐍 - such a lovely evening 😊

Looking for an #immunology #postdoc? Then I *THOROUGHLY RECOMMEND* @mainilab.bsky.social Incredibly supportive PI & environment Cutting-edge science🧪 (dissecting hepatic #immunity in people w/ #hepatitisB & #cancer) Fab team & collabs Great institute APPLY NOW: www.linkedin.com/jobs/view/re...

Any post-docs interested in dissecting host-pathogen interactions in tissue- check out our advert on LinkedIn to join us @UCL IIT Pears Building! #immunosky

Open call for new research groups @pasteur.fr in Paris lots of immunology themes welcome #immunosky #IDsky #Scisky 🧪🥼🔬 get in touch if you have questions

Thrilled to share that our paper www.nature.com/articles/s41... is featured in a fantastic Nature News & Views piece by thomastueting.bsky.social! 🎉 Grateful for the spotlight on our research and its impact on understanding cancer immunology. www.nature.com/articles/d41... 👀👉 rdcu.be/d3cRz

Why do some people, despite SARS-CoV-2 exposure, not develop an infection? An ultra-early interferon response blocks Covid www.thelancet.com/journals/ebi... adds to protection from pre-existing, cross-reactive T cells in some people

An excellent PhD opportunity available in our team: long-range consequences of parasite infection, gut-lung communication and helminth-viral co-infection. Part of the EastBio training programme. Closing date 17th January. Please get in touch! www.findaphd.com/phds/project...

Thanks all for another great year's team work @UCL IIT and for all those fun Secret Santa pressies that kept us guessing! #immunosky

Speaker line up for #EMBOTissueImmunity to take place in Basel 🇨🇭 26-29 August 2025. Come join @maurogaya.bsky.social and I for some fantastic #immunology along the Rhine! Please share this invitation - we hope you will join us. Registrations will be open soon.

Also out now.. after peer review, our analysis of blood transcriptional biomarkers of acute respiratory viral infection leveraging the SARS-CoV-2 human challenge model: www.nature.com/articles/s41...

More #evidence for the existence of #CD8 #Regulatory #Tcells www.nature.com/articles/s41... Check our previous paper also> #KIR+CD8+ #T cells suppress pathogenic T cells and are active in autoimmune diseases and COVID-19 | Science www.science.org/doi/10.1126/...

Engineering T cells with capability for a switch in specificity www.cell.com/immunity/ful... for better homing agents, to improve safety and efficacy vs cancer and other emerging T cell interventions

A vaccine platform targeting lung-resident memory CD4+ T-cells provides protection against heterosubtypic influenza infections in mice and ferrets www.nature.com/articles/s41...

Our top-rated #bioinformatics #training course 'Omic data analysis and visualisation using R' starts in less than 2 weeks (9 Dec) Perfect for those who want to gain new #DataAnalysis and #omics skills 🤩 Don't miss out! Book your place now 👉 bit.ly/4gXvxOF

Are neutrophils "good" or "bad"? Rana Herro reviews the current literature here: rdcu.be/d0Rt7

Slowly but surely the migration from 🐦➡️🦋 is happening and those from our Institute are moving too ❤️ You can find those working at the UCL institute for immunity and transplantation (aka the 🍐🍐 building, if you know, you know) here: go.bsky.app/84owGLt #immunosky #academicsky 🧪

Great review of receptor ligand pairs mediating NK regulation of T cells

🚨4yr PhD in Infection & Immunity🚨 Hosted at #UCL in the new Institute for Immunity & Transplantation (Pears Building, north London) 3x6wk rotations before selecting a lab for PhD Deadline: Jan 10 (Home tuition Fees+stipend) www.ucl.ac.uk/work-at-ucl/... #AcademicSky #PhDOpportunity #Immunosky