A study led by @ailithewing.bsky.social has gained new insights into how high grade serous ovarian cancer tumours emerge and grow, opening new avenues to develop better treatments: edin.ac/40vjn9a @natcomms.nature.com @cmvm-edinburghuni.bsky.social

Surprising findings of BRCA mutations on the Fallopian tubes. Result of a tremendous team effort with @shenhui1986.bsky.social @vainstitute.bsky.social, Chuck Drescher @fredhutch.bsky.social, and Jarrod Marto @danafarber.bsky.social. @pennmedcso.bsky.social www.nature.com/articles/s41...

Delighted our work using aneuploidy as a biomarker of colorectal cancer risk in inflammatory bowel disease is out: gut.bmj.com/content/earl... The initial reaction from patients&families has been overwhelming Led by Ibrahim AlBakir @yosoykit.bsky.social @cancerresearchuk.org @icrlondon.bsky.social

🌟NEW PREPRINT ALERT!🌟 We are very pleased to introduce #StrainDifferences: “Genetic background sets the trajectory of cancer evolution” www.biorxiv.org/content/10.1... 🧵[1/12]

We have an open #PhD #studentship as part of our "Black Leaders in Cancer" programme at @crukconvergence.bsky.social & @icrlondon.bsky.social. About computational modelling of T-cell evolution in cancer. www.findaphd.com/phds/project... I'm looking forward to meeting prospective students #CRUKfunded

Well done Dr Jan! A PhD student with @mstaylor.bsky.social who passed his viva yesterday. We’ll miss having the indel expert in the building! 📷 artistic credit to Martin

new out in Nature www.nature.com/articles/s41...

www.nature.com/articles/s41... #instability #evolution #cancer

People working on the causes or consequences of #aneuploidy or #CIN. Reply if I missed you and you want adding to the list go.bsky.app/G8wHoXx

Cancer cells often harbor oncogenes outside chromosomes on extrachromosomal DNA (ecDNA), which is unevenly inherited by dividing cells. We reported in Nature last week that collectives of ecDNAs are inherited together by dividing cancer cells. 1/ www.nature.com/articles/s41...

Huge resource of MSK-IMPACT "genomes", what a treasure trove! Automated real-world data integration improves cancer outcome prediction www.nature.com/articles/s41...

We are happy to announce the release of a new #nf-core workflow -- #oncoanalyser performs an exhaustive analysis of single-patient cancer sequencing data using methods developed by the Hartwig Medical Foundation Australia. (1/5)

Tune in today at 2pm UK time for an online seminar explaining why our lab cares about Chromosomal Instability in cancer - as part of a wonderful lecture series on CIN