Organelles do NOT have a single uniform pH. And if you think they must, because “protons diffuse fast,” this paper is for you. A thread on why that assumption is wrong; and what we found instead. 🧵 1/n

Microsecond Time-Resolved Cryo-EM Based on Jet Vitrification www.biorxiv.org/content/10.1... #rhodopsins

"Most cameras at the time were mechanical marvels, and I couldn’t build [one] to save my life. So I thought, ‘I’ll make one with no moving parts and that’ll annoy the hell out of [the mechanical engineers]’." Generational showboating from Steve Sasson www.bbc.com/future/artic...

There's an "anything but sleds" tradition at my university come heavy snowfall like we had this past week. Some inventive favorites: laundry baskets, kayaks, kiddie pools and woks... (1/3)

TT in Experimental Biophysics The Danish Institute for Advanced Study and the Dept of Physics, Chemistry and Pharmacy at the University of Southern Denmark is hiring a tenure track Assistant Professor in Biophysics or a related discipline fa-eosd-saasfaprod1.fa.ocs.oraclecloud.com/hcmUI/Candid...

Curtis et al. find T305A & T306A CaMKIIα mutations drive actinin-mediated spine growth w/o need for kinase activity or cLTP cues, echoing Tullis et al.’s 2023 report “LTP induction by structural rather than enzymatic functions of CaMKII” #Science #NeuroSky www.jneurosci.org/content/45/4...

#LivingArchitectures We put cells and cytoskeleton filaments on the architecture of the musée d'Orsay. www.musee-orsay.fr/fr/agenda/ev... Scientists of the #CytoMorphoLab adapted their protocols to illustrate the questions that keep them awake at night. -> Two shows on the 24th and 25th of January.

Aerosol transmission of SARSCoV2 virus is the dominant route for transmitting COVID-19. 👏'2025 Faraday Horizon Prize for advancing understanding of the physicochemical properties of exhaled aerosols, and their impact on transmissibility of respiratory pathogens.' @rsc.org www.rsc.org/standards-an...

The ghost town of Helena, CA. Widelux F7 // Kodak Aerochrome color infrared film #believeinfilm #filmisnotdead #film #filmphotography #infrared #35mm #widelux #panorama #landscape #panophotos #ghosttown

INCREDIBLE CURVES

Almost nine years since the math library added tau in python 3.6, I am once again asking the numpy contributors to follow suit

Another panorama from Ontario's Sleeping Giant Provincial Park taken this past summer. The Giant can be seen resting on the horizon, behind the "Sea Lion" rock formation. #infrared #ir #photography #nature #landscape

Given the choice between netball and this... #IR #Photography #RedWed

MISO: microfluidic protein isolation enables single-particle cryo-EM structure determination from a single cell colony. Or from a single dish of HEK cell culture in the case of two membrane proteins. Out in Nature Methods now! lnkd.in/gpyBSceg Wonderful collaboration with the Efremov lab.

Going through some older photos as the last of summer's leaves finish falling #infrared #photography #panorama

At the heart of Purdue University's campus, the Engineering Fountain (and totally not the Atari logo) sublimates into brilliant white light, as red auroral curtains dance overhead #Photography #BlueSkyArtShow #Bright #Aurora #LongExposure

A long walk turned into a much longer walk doubling back home for a tripod, then ambling around my university's campus for a couple of hours. #Photography #Aurora #LongExposure

A local spin on Iceland's "Sun Voyager" sculpture, featuring a university crew team's boat rack in the foreground, during the first few minutes of this past week's solar activity. Stacking my phone, keys and wallet beneath the lens worked in a pinch as another #CraftyTripod #Photography #Aurora

One of the first few serendipitous shots taken out on a walk during this Tuesday's burst of solar activity. It's rare that alerts of "possible aurorae" have materialized into atmospheric fantasia near me, so ended up using a bollard as another #CraftyTripod for the year. #Photography #Aurora

Coming back to this past week's #aurorae photos with a devil on both shoulders

Sure, ice scraping's a pain and biking now requires gloves, but we're making the most of the season's first snowfall #photography #winter #snow

Static Electricity Helps Parasitic Nematodes Leap onto Insects www.scientificamerican.com/article/stat...

It’s my working theory that seniority is directly related to the size (or #) of screens an audience member loses themself in: • trainees typing on phones • profs reviewing drafts on ipads • this guy, 26 min over, turning to read his own projected slides

For my #sciencejobs in #academia tenure track hopefuls: UCSB Bioengineering is looking for a new assistant professor! Go work near the beach! Get to know the department interim chair, who was my doctoral advisor! Do science with awesome colleagues! recruit.ap.ucsb.edu/JPF03025

No Kings protest in Greater Lafayette, Indiana on October 18th, 2025 #NoKings #Photography

My new piece in @medpagetoday.com We Can Stop Deadly Hospital Outbreaks - So Why Aren't We? Genomic surveillance can prevent outbreaks from spreading, save lives, and costs. So what’s holding it back from being implemented in hospitals? #IDSky www.medpagetoday.com/opinion/seco...

Just published, a study describing a taste-based flu test yes, chewing gum that could tell you if you have influenza. The gum contains a sensor that detects the flu enzyme neuraminidase & releases a compound called thymol that changes taste when the virus is present. pubs.acs.org/doi/10.1021/...

Another couple from this past summer. Taken about an hour and 580 m / 1900 ft in vertical elevation apart. Much easier juggling two cameras on the way down than up!

A welcome surprise to see this heron stalk into place while out crossing our pedestrian bridge #infrared #photography #nature

My HPLC was definitely overlooked www.nature.com/articles/d41...

Taken along the US-Canadian border. Fun fact: so long as you go over in a barrel, import restrictions don't apply here. #IR #LongExposure #WaterfallWednesday #Minnesota

Super luminous blues and Wood effected yellows, give a child-like, sugar-high-saturated preview to autumn #photography #bluetue #infrared

And as a bonus, here's a false-color composite of the same. Blue is mapped to all of visible, green is infrared beyond 850nm, and red is the methane band at 889nm. 🔭 #astrophotography #saturn

Shots you text your parents like "Relax! Nobody got hurt." Taken for effect along the rim of Goosenecks State Park. #Utah #Photography #Relax #BlueSkyArtShow

My heart goes out to all the life science imaging folks feeling left out with their microtomes and tomographic techniques

Taking in some new sights while visiting Notre Dame's campus last week with my infrared camera in tow

It's hard to believe some people still call it the "Sears Tower"... because it's not. That's on S. Wacker, which is about another mile west and regrettably out of frame. #Chicago #Photography #BelieveInFilm

Another favorite from this past winter’s road trip out west, taken along an unplanned detour up the side of Colorado’s Blanca Peak #TheRoad #BlueSkyArtShow #IR #Landscape #Mountains

No longer content just listening to them rattle around in the glovebox, I finally got a few rolls of film from back in December developed and scanned. #Colorado #Roadtrip #Nature #Landscape #Scape #Mountains #BelieveInFilm

Nature Biomedical Engineering is hiring again! This time we're hoping to add an editor with machine learning expertise to the team (although we are open to those with other relevant expertise!) Deadline is Oct 20. Please RT! springernature.wd3.myworkdayjobs.com/SpringerNatu...

Letting off steam #ir #infrared #photography #nature

Two water-loving dogs and their owner, trying his best. A story in four parts. #street #photography #dogs #fountain

I usually avoid UV photography (vs UVIF) because I feel like it washes the world out in a cancerous coal-and-cigarette haze. Still, coming around to appreciate an industrial aspect to it with a bit of IR leak and a channel swap. #uv #uvp #photography #pano #photowalk

In a study out this week, Zhang et al. find poor clearing of PSD-95 and other neuronal proteins drives an overabundance of dendritic spines, a hallmark of Fragile X. Centrally activating autophagy to counter this improved cognition in mouse models. #NeuroSky #SciSky www.nature.com/articles/s41...

Dipping into memories with this sea-side photo I took alongside wonderful people I hope to see again someday #BlueSkyArtShow #Summer #Photography #Beach #Kayaking #Greece

Are you more left or right brained? What about your synaptosomal preps? Jiang et al. report left-higher phosphorylation asymmetry in postsynaptic proteins from striatum w/ SH3RF2 as a key regulator to PP1-mediated CaMKII & AMPAR (de)phosphorylation #NeuroSky #iGluR www.nature.com/articles/s41...

PSA: If there is an academic you hate, toady is a great time to inquire how much of their summer research and writing plans they've accomplished.

Went out to capture the observation tower in the background, but saw an opportunity with the fisher caught in afternoon sun. #infrared #photography #bnw #lightrays #MinimalMonday

Some more shots from the #infrared half to this Saturday afternoon's photowalk #ir #photography #nature #industry

another perspective on a local artist's mural #ir #infrared #photography #pano #lafayette #pano