A new review from the Doudna Lab lab on tissue-targeted in vivo delivery of gene editors: https://www.nature.com/articles/s41587-025-02945-w #CRISPR #delivery

RNA structures are hard to solve, but experimental and computational approaches are evolving. This new Perspective in @natbiotech.nature.com shows how their interplay will be the driving force to help the field forward. www.nature.com/articles/s41...

How do you detect transgenes in genome-edited crops? We tested several methods and report our findings in 2 back-to-back papers: onlinelibrary.wiley.com/doi/10.1111/... rdcu.be/eLgUi

The COP16 decision established a multilateral mechanism for digital sequence information benefit-sharing. DSI researchers assess what has been accomplished so far and identify remaining challenges go.nature.com/4nBE4t8 rdcu.be/eJnid

Redefining druggable targets with artificial intelligence - @wcmenglanderipm.bsky.social @aihealthmit.bsky.social go.nature.com/4fHNMYi

How can we engineer B cells to treat diseases? Read about the latest developments of this exciting field in this new Review out now in @natbiotech.nature.com www.nature.com/articles/s41...

Can senolytics reverse or slow aging? Table of companies pursuing this goal. So far the results are questionable. @natbiotech.nature.com www.nature.com/articles/s41...

Gene regulatory networks are crucial for understanding complex gene regulation in plants and could help improve crops for more sustainable and climate-resilient agriculture. Read about it in this Review out now in @natbiotech.nature.com www.nature.com/articles/s41...

This Review presents a classification system of hybrid engineered biological systems to support researchers in making design choices, out now in @natbiotech.nature.com www.nature.com/articles/s41...

Base editors model mitochondrial disease #NBTNV - @mikrobenjaeger.bsky.social go.nature.com/45O9PJM

Anatomy of the 23andMe fall and implications for consumer genomics go.nature.com/3Hf6sBE

Overcoming key hurdles for the development of next-generation anaerobic cultivation methods could have major impacts on microbial community research and applications. Read how in this new Perspective in @natbiotech.nature.com www.nature.com/articles/s41...

A call for built-in biosecurity safeguards for generative AI tools go.nature.com/3GIpTlR

Here we share thoughts on next-gen cultivation: rdcu.be/ejPSb. Hope it helps 😄 Was fun to write with great colleagues @lisamaierlab.bsky.social @jselkrig.bsky.social @baerboletta.bsky.social @typaslab.bsky.social @mmmicrobiomelab.bsky.social @leibniz-dsmz.bsky.social @westermannlab.bsky.social

1/ We need new ways of producing foods and fuels to minimise our impact on our planet. Our new paper now in @natbiotech.nature.com examines whether microbes hold the key to producing foods and fuels in the future Open access: rdcu.be/eiIUu nature.com/articles/s41...

The development of therapeutic cancer vaccines is seeing exciting progress recently. Curious how researchers are dealing with challenges to translate new technologies to the clinic? @natbiotech.nature.com asked experts for an update. www.nature.com/articles/s41...

Cell therapies are transforming our ability to treat cancer but are out of reach for many patients. @natbiotech.nature.com asked experts to share their insights into pressing challenges and promising strategies to make these therapies more broadly accessible www.nature.com/articles/s41...

A look back at what vaccines have done.

Proud of our new perspective describing the role of mathematical biology for immunotherapy www.nature.com/articles/s41... @natbiotech.nature.com

This month, we've focused on recent developments as well as challenges in cancer immunotherapy, including cancer vaccines, immune checkpoint inhibitors, and CAR-engineered cells. Please read more👇

Innate immune cells are promising candidates for cancer immunotherapy and various engineering strategies can be employed to set them up for success. Read about is in this Review in @natbiotech.nature.com and don't forget to check out our full Focus Issue! www.nature.com/articles/s41...

🔥New Night Science paper!! Discovery happens when your initial plans fall apart but it requires you to have a particular mindset: it's not extraverted, orderly, neurotic or agreeable that's the most important – discovery requires an OPENNESS to new ideas and unexpected insights.

Shares of US drugmakers fell after reports that @fda.gov top vaccine official, Peter Marks, had been forced to resign, as the Trump administration undertakes an overhaul of federal health agencies #NBTNewsBeat www.reuters.com/business/hea...

Check out the state of the field of engineered bacteria for cancer therapy in this Comment in @naturebiotech.bsky.social www.nature.com/articles/s41...

Modulating induced proximity at the cell surface is a powerful engineering strategy that can find diverse applications in basic and translational science. Curious to learn about emerging modalities in this space? Read this review out now in @naturebiotech.bsky.social www.nature.com/articles/s41...

Nanopore technology might be able to sequence proteins soon! Read about the road ahead in this exciting Perspective rdcu.be/edWPi in @naturebiotech.bsky.social

The program of the CiRT2025 meeting is out: meeting2025.cirt-net.org/program.html. I will be sharing my top 10 tips on publishing with @naturebiotech.bsky.social. See you there?

Our article is now out in Nature Biotechnology. Here we outline challenges for developing broad-based mucosal vaccines for respiratory viruses. Check it out! Congrats to Junghwa and Jordan from my lab and to other co-authors! www.nature.com/articles/s41...

Natural and engineered Cas12 and TnpB variants offer diverse applications in genome editing and diagnostics - read all about it in this Review in @naturebiotech.bsky.social www.nature.com/articles/s41...