Thomas Clavel
@tclavel.bsky.social
📤 175
📥 159
📝 16
Passoniate microbiome research; www.clavel.ukaachen.de
reposted by
Thomas Clavel
Lisa Maier Lab | Tübingen
8 days ago
We’re hiring 2 Postdocs (f/m/d) in Drug–Microbiome–Host Interactions 🦠💊 Focus: how non-antibiotic drugs shape the gut microbiome, drug efficacy & side effects.
#PostdocJobs
#Microbiome
#AcademicJobs
Full job ad:
lisamaierlab.com/wp-content/u...
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https://lisamaierlab.com/wp-content/uploads/2025/12/2025_Postdoc_Job-Ad.pdf
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Now published 🔥 Feeding your gut microbes with complex carbohydrates can help preventing colorectal cancer by reducing the production of secondary bile acids. Perhaps NiMe diet
@jenswalter15.bsky.social
? THX team & Sören Ocvirk ⭐ Thx
www.sfb.tum.de/1371/microbi...
. Article 👉
doi.org/10.1136/gutj...
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Secondary bile acid production by gut bacteria promotes Western diet-associated colorectal cancer
Background Western diet and associated production of secondary bile acids (BAs) have been linked to the development of sporadic colorectal cancer (CRC). Despite observational studies showing that seco...
https://doi.org/10.1136/gutjnl-2024-332243
11 days ago
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reposted by
Thomas Clavel
NFDI4Microbiota
14 days ago
Save the Date! 📅 The NFDI4Microbiota Annual Conference 2026 will take place 15–17 September 2026 and will be a joint event with other biodata-related NFDI consortia. Stay tuned for more details!
#onenfdi
#NFDI4Microbiota
#rdm
#microbiota
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reposted by
Thomas Clavel
Michael Zimmermann Lab
14 days ago
📍Our paper is out!📍 Here, we show the development of a GC-MS/MS method for the quantification of 120 compounds produced by gut bacteria, including short-chain fatty acids, indols, nucleotides, organic acids, and amino acid derivatives. Check it out!
link.springer.com/article/10.1...
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Development of a GC-MS/MS method to quantify 120 gut microbiota-derived metabolites - Analytical and Bioanalytical Chemistry
The gut microbiota produces metabolites that are important for host physiology and have critical roles in the development of diseases, such as metabolic disorders, cardiovascular diseases, and cancer....
https://link.springer.com/article/10.1007/s00216-025-06256-6
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reposted by
Thomas Clavel
Jörg Vogel
18 days ago
Franziska Faber and I are recruiting shared postdocs, PhD students to work on Fusobacterium & new BGCs.
www.helmholtz-hiri.de/fileadmin/HI...
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reposted by
Thomas Clavel
Lisa Maier Lab | Tübingen
21 days ago
New paper from the lab! Led by Patrick Müller: we show that non-antibiotic compounds — but not macrolide antibiotics — can induce an efflux pump that protects Bacteroidaceae from macrolides. A neat twist on drug–microbe interactions...
www.tandfonline.com/doi/full/10....
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reposted by
Thomas Clavel
DSMZ Digital Diversity
about 1 month ago
📣 Open position: We are looking for a new
#ScientificLead
for the
#SILVA
database 🧬🖥️ You will be responsible for guiding the development of this important resource and for curating the SILVA taxonomy🌳and more! 👉
www.dsmz.de/dsmz/career/...
Read and share ‼️
#sciencejobs
🦠🧪
#career
#taxonomy
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reposted by
Thomas Clavel
Tom Hitch
about 2 months ago
Want to delineate genera? We have been optimising POCP, and propose POCPu, which stops the 'double counting' of proteins in POCP by only allowing unique matches. We also speed up, and benchmarked, the analysis using DIAMOND;
peerj.com/articles/202...
(now implemented in Protologger)
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Fast and robust estimate of bacterial genus novelty using the percentage of conserved proteins with unique matches (POCPu)
Accurate taxonomic assignment of bacterial genomes is essential for identifying novel taxa and for stable classification to enable robust comparison between studies. Bacterial genus delineation relies...
https://peerj.com/articles/20259/
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Great work from our FAIR science master Charlie (
www.linkedin.com/in/charliepa...
) to delineate bacterial genera:
peerj.com/articles/202...
. We hope this will help many. The POCPu calculation is now implemented in
protologger.bi.denbi.de
by
@tcahitch.bsky.social
. Thanks for the hard work you 2 ⭐⭐
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Fast and robust estimate of bacterial genus novelty using the percentage of conserved proteins with unique matches (POCPu)
Accurate taxonomic assignment of bacterial genomes is essential for identifying novel taxa and for stable classification to enable robust comparison between studies. Bacterial genus delineation relies...
https://peerj.com/articles/20259/
about 2 months ago
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reposted by
Thomas Clavel
NFDI4Microbiota
about 2 months ago
Need a hand with your #Nextflow or #nfcore pipeline? Join our weekly drop-in session — every Friday 10–11 CET with Daniel Straub (Uni Tübingen). Ask questions, get tips, and connect with the community! 📍 Zoom:
tinyurl.com/mwz84xvb
#Nextflow
#nfcore
#Bioinformatics
#OpenScience
#NFDI4Microbiota
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A place to be 👇 Highly recommended ⭐⭐⭐⭐⭐
add a skeleton here at some point
2 months ago
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reposted by
Thomas Clavel
Emma Slack
2 months ago
We have an opening for a postdoctoral researcher in my group at the Botnar Institute for Immune Engineering in Basel, Switzerland. The project is aimed at developing novel mucosal adjuvants for application in oral vaccines. Deadline to apply 16.11.25! Please re-post 🔬🧬
join.com/companies/im...
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Botnar Institute of Immune Engineering - BIIE (Zürich): Postdoctoral Researcher (100%): Mechanisms of action of mucosal adjuvants
Botnar Institute of Immune Engineering - BIIE has a job opening for Postdoctoral Researcher (100%): Mechanisms of action of mucosal adjuvants in Zürich (published: 30.10.2025). Apply now or check the ...
https://join.com/companies/immune1/15114497?utm_medium=social_sharing&utm_source=copy_link
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reposted by
Thomas Clavel
NFDI4Microbiota
2 months ago
☕ Grab your coffee and join our next NFDI4Microbiota Coffee Talk! 📅 Mon, 27 Oct 2025 | 14:30–15:30 CET 🎙️ Daniel Straub (QBiC Tübingen) 💬 “Meta-omics Analysis at a Bioinformatics Core Facility – As FAIR as Possible”. More info here:
nfdi4microbiota.de/c...
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reposted by
Thomas Clavel
bioRxiv Microbiology
3 months ago
A toolkit for transposon libraries and functional genomics in intestinal Bacteroidales
https://www.biorxiv.org/content/10.1101/2025.10.10.681549v1
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reposted by
Thomas Clavel
Michael Zimmermann Lab
3 months ago
📍Paper alert 📍 Our new preprint is available on:
chemrxiv.org/engage/chemr...
Here, we show the development of a GC-MS/MS method for the quantification of 120 compounds produced by gut bacteria, including SCFA, indols, organic acids, and amino acid derivatives.
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Development of a GC-MS/MS method to quantify 120 gut microbiota-derived metabolites
The gut microbiota produces metabolites that are important for host physiology and have critical roles in the development of diseases, such as metabolic disorders, cardiovascular diseases, and cancer....
https://chemrxiv.org/engage/chemrxiv/article-details/68c723ae9008f1a4677dc87d
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reposted by
Thomas Clavel
Tom Hitch
3 months ago
The main work from my time in Aachen is now out 🎉 if you have wanted to make a SynCom that captures the functional-landscape of microbiota, MiMiC2 makes that possible based on metagenomic data! 1/7
doi.org/10.1093/isme...
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Function-Based Selection of Synthetic Communities Enables Mechanistic Microbiome Studies
Abstract. Understanding the complex interactions between microbes and their environment requires robust model systems such as synthetic communities (SynCom
https://doi.org/10.1093/ismejo/wraf209
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Interested in the design of defined microbial communities for fundamental research and applications? Hope this work & tool will help you 👇 As always
@tcahitch.bsky.social
has been a driving factor ⭐⭐⭐!
github.com/ClavelLab/Mi...
;
academic.oup.com/ismej/advanc...
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Validate User
https://academic.oup.com/ismej/advance-article/doi/10.1093/ismejo/wraf209/8256658?login=false
3 months ago
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reposted by
Thomas Clavel
Emma Slack
4 months ago
Come and be my colleague at the Dunn School! It‘s a brilliant place to work and exciting to be building up our immunology team. Do apply. Do pass on the news 💉🧬🦠🔬🧫
add a skeleton here at some point
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reposted by
Thomas Clavel
NFDI4Microbiota
4 months ago
We’re heading to Jena for two exciting events! 📍 DGHM 2025 – 24 Sept Workshop: Data madness: Navigating Host Microbiomes Featuring VirJenDB – virus sequence discovery & analysis Details 👉
programme.conventus....
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reposted by
Thomas Clavel
Steven Salzberg
4 months ago
We're still not finding any good evidence for a microbiome in any cancer type: see our new paper in @ScienceTM led by PhD student Yuchen (Peter) Ge
www.science.org/doi/10.1126/...
and the accompanying news piece,
www.science.org/content/arti...
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Comprehensive analysis of microbial content in whole-genome sequencing samples from The Cancer Genome Atlas project
An analysis of TCGA whole-genome sequencing samples yields a comprehensive resource for investigating the role of microbes in cancer.
https://www.science.org/doi/10.1126/scitranslmed.ads6335
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reposted by
Thomas Clavel
Carolin Wendling
4 months ago
Interested in exploring prophages in your (meta)genomes, but don't know how and where to start? We've put together a beginners guide to exploring viral diversity in prokaryotes
@marievasse.bsky.social
@sebwielgoss.bsky.social
@oxunipress.bsky.social
add a skeleton here at some point
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reposted by
Thomas Clavel
NFDI4Microbiota
4 months ago
Planning, sequencing… and now analysis. 📊 ☕ Coffee Talk: Getting Your Microbiome Research on the Road – Managing Your Data using Qiita 🗓️ Aug 25, 2025 | 14:30 CEST 👉 More info:
tinyurl.com/2m9jpf2p
👉 Workshop (Oct 22–24, Gießen):
tinyurl.com/4w8mczh7
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reposted by
Thomas Clavel
Geraldine Zimmer-Bensch
4 months ago
🌍 Open Call! RWTH Aachen University invites postdocs from outside the EU to apply for the “Port to Europe” Fellowship (24 months funding, all disciplines). Start your research journey at one of Europe’s top universities! 🚀 Deadline: Oct 5, 2025. 👉https://rwth-aachen.de/go/id/botjje/lidx/1
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reposted by
Thomas Clavel
Michael Zimmermann Lab
5 months ago
Do you have experience in metabolomics/lipidomics/exposomics? Check out the EMBL ARISE2 Fellowship Programme! 🔗
www.embl.org/training/ari...
📩 Contact: Juan Antonio Vizcaíno — Team Leader, EMBL-EBI 🔗
www.ebi.ac.uk/people/perso...
📌 Applications close soon! 📆 30/09/2025 More info below👇
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reposted by
Thomas Clavel
Typas Lab
5 months ago
Ready to lead pioneering research that bridges systems-level investigations of biological systems to molecular mechanism? The EMBL Molecular Systems Biology Unit in Heidelberg is hiring a Group Leader!
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Group Leader – Molecular Systems Biology Unit
Are you ready to lead groundbreaking research in Molecular Systems Biology? Join us at EMBL! We are seeking a motivated scientist to lead an independent research group, addressing original biological ...
https://embl.wd103.myworkdayjobs.com/en-US/EMBL/details/Group-Leader----Molecular-Systems-Biology-Unit_JR2062
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reposted by
Thomas Clavel
Lisa Maier Lab | Tübingen
6 months ago
Finally online! Our latest research is out
@nature.com
: We show that non-antibiotic drugs can disrupt colonization resistance, raising the risk of enteric infections.
rdcu.be/ewwrG
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Non-antibiotics disrupt colonization resistance against enteropathogens
Nature - Non-antibiotic drugs from a wide range of therapeutic classes can alter the ability of gut commensals to resist invasion by enteropathogens, a previously underappreciated side effect of...
https://rdcu.be/ewwrG
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reposted by
Thomas Clavel
François Leulier
6 months ago
A pure « délice » to have followed this story unfolding under our eyes. Congrats
@ameliejoly.bsky.social
brilliantly followed-up by
@lucasrebiffe.bsky.social
.
@filipedevadder.bsky.social
and I were/are so lucky to work with gifted Ph’D candidates like you!
add a skeleton here at some point
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reposted by
Thomas Clavel
NFDI4Microbiota
6 months ago
Try cloud-based microbiome workflows with CloWM—no installation needed! 📍 4th NFDI4Microbiota Annual Conference |Cologne 📆 Oct 2 | Registration is free 🔗
events.hifis.net/eve...
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Congrats
@baerboletta.bsky.social
👏 Highly deserved & best possible ambassador for the field
www.embo.org/press-releas...
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Outstanding life scientists elected to the EMBO Membership – Press releases – EMBO
Sixty-nine new members join the community of leading life scientists in Europe and beyond
https://www.embo.org/press-releases/outstanding-life-scientists-elected-to-the-embo-membership/
6 months ago
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reposted by
Thomas Clavel
Nature Microbiology
6 months ago
#NewResearch
🚨Out now! Human gut bacteria bioaccumulate forever chemicals, in intracellular aggregates and colonization of gnotobiotic mice with these bioaccumulating bacteria increases faecal PFAS excretion.
@kiranrpatil.bsky.social
#MicroSky
#MicrobiomeSky
🦠
www.nature.com/articles/s41...
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Human gut bacteria bioaccumulate per- and polyfluoroalkyl substances - Nature Microbiology
Human gut bacteria bioaccumulate per- and polyfluoroalkyl substances (PFAS), commonly known as forever chemicals, in intracellular aggregates. Colonization of gnotobiotic mice with bioaccumulating bac...
https://www.nature.com/articles/s41564-025-02032-5?utm_source=bluesky&utm_medium=social&utm_campaign=nmicrobiol
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reposted by
Thomas Clavel
NFDI4Microbiota
6 months ago
Join our NFDI4Microbiota Coffee Talk: Ivan Belyaev
@microverse.bsky.social
presents BEXIS2, a flexible platform for microbiology metadata. June 30 at 14:30 CEST. More info here:
tinyurl.com/mudhdnra
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reposted by
Thomas Clavel
NFDI4Microbiota
6 months ago
🧫 Registration is open! Join the 4th NFDI4Microbiota Conference in Cologne 📅 Sept 30–Oct 2 | Theme: From Lab to Publication Hands-on workshops, keynotes, posters | Registration is free 📝 Register by Aug 31:
events.hifis.net/eve...
#FAIRdata
#Microbiome
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reposted by
Thomas Clavel
Noah Fierer
6 months ago
Hope this is useful - consensus statement "Guidelines for preventing and reporting contamination in low-biomass microbiome studies"
rdcu.be/er3Io
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Guidelines for preventing and reporting contamination in low-biomass microbiome studies
Nature Microbiology - In this Consensus Statement, the authors outline strategies for processing, analysing and interpreting low-biomass microbiome samples, and provide recommendations to minimize...
https://rdcu.be/er3Io
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reposted by
Thomas Clavel
NFDI4Microbiota
7 months ago
The #NFDI4Microbiota Flex Funds Call 2026 opens June 16! Support for infrastructure, workflows, training & more in microbiology. Deadline: Aug 11. Details:
nfdi4microbiota.de/n...
#NFDI4Microbiota
#OpenScience
#FAIRdata
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reposted by
Thomas Clavel
Lisa Maier Lab | Tübingen
7 months ago
Ever wondered why proton pump inhibitors raise the risk of C. diff infections? Is it due to pH shifts or direct antibacterial effects on the gut microbiome? We think it’s the pH. 🧪💡 Dive into Julia & Patrick’s new paper for the full story! 📖👇
#Microbiome
#PPI
doi.org/10.1080/1949...
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Proton-pump inhibitors increase C. difficile infection risk by altering pH rather than by affecting the gut microbiome based on a bioreactor model
Clostridioides difficile infections often occur after antibiotic use, but they have also been linked to proton-pump inhibitor (PPI) therapy. The underlying mechanism – whether infection risk is due...
https://doi.org/10.1080/19490976.2025.2519697
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reposted by
Thomas Clavel
Westermann Lab
7 months ago
Our latest:
www.cell.com/cell-reports/fulltext/S2211-1247(25)00615-1
. Links Bacteroides cell size w/ gene expression. Protocol works even for single cells. 🦠 Shoutout to
@elisebor.bsky.social
,
@emmanuel-saliba.bsky.social
,
@lbarquist.bsky.social
,
@jorg-vogel-lab.bsky.social
, Till Strowig & KC Huang.
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Low-input RNA-seq suggests metabolic specialization underlying morphological heterogeneity in a gut commensal bacterium
Bornet et al. investigate the morphological heterogeneity of Bacteroides thetaiotaomicron cells observed both in laboratory culture and inside the mammalian GI tract. The authors show that cell size i...
https://www.cell.com/cell-reports/fulltext/S2211-1247(25)00615-1
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reposted by
Thomas Clavel
Karina Xavier Lab
7 months ago
Call for our new PhD program is open. Come join one of our labs at Gulbenkian Institute for Molecular Medicine - Lisbon-Oeiras, Portugal. Help us spread the word
add a skeleton here at some point
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reposted by
Thomas Clavel
NFDI4Microbiota
7 months ago
Join NFDI4Microbiota as a participant for 2026–2031! Gain early access to tools, bilateral exchange via an early-career ambassador, and targeted support for ELNs, DMPs, SOPs & FAIR data. Apply by June 10, 2025:
www.nfdi4microbiota....
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reposted by
Thomas Clavel
Karina Xavier Lab
7 months ago
Call for Group Leaders - Join us at GIMM, 7 days till the deadline!
add a skeleton here at some point
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reposted by
Thomas Clavel
Andreas Peschel
8 months ago
Join us in Tubingen as a Junior Research Group Leader if you do research on
#ESKAPE
pathogens and infections and are interested in the highly cooperative environment of
@dzif.bsky.social
and
@cmfi.bsky.social
! Please send your application or forward to colleagues!
uni-tuebingen.de/universitaet...
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reposted by
Thomas Clavel
NFDI4Microbiota
8 months ago
📅 Save the Date: NFDI4Microbiota Annual Conference in Cologne, 29 Sep–2 Oct 2025! Free, open to all hands-on workshops & scientific talks on microbial data integration. Network and shape the future of microbiome research. Details coming soon!
#NFDI4Microbiota
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reposted by
Thomas Clavel
BacDive
8 months ago
A new look for BacDive 🖥️🦠! We are excited to introduce the new BacDive design✨ and now invite all users to try it out. Tell us what you think, we look forward to your feedback! You can find it at 👉
beta.bacdive.dsmz.de
or by clicking the red “New Design” button on every BacDive page.
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reposted by
Thomas Clavel
Paul Cotter
8 months ago
PLEASE SHARE We’re hiring a contract
#bioinformatician
(research officer) to analyse
#microbiome
data from an ongoing, exciting project focusing on preterm birth prevention with oral probiotics
topjobs-teagasc.thehirelab.com/LiveJobs/Job...
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reposted by
Thomas Clavel
NFDI4Microbiota
8 months ago
New training alert! 🚨 NFDI4Microbiota & DZIF offer an Intro to R online course (June 23–25, 2025). Ideal for beginners in R & bioinformatics. Apply by June 6:
events.hifis.net/eve...
#RStats
#OpenScience
#Microbiome
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Impressive lineup of speakers 🔥 In a nice city 😄 Do not miss the opportunity 🤙
add a skeleton here at some point
8 months ago
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reposted by
Thomas Clavel
Emma Slack
8 months ago
This will be a fantastic meeting 👇🏻 A little bird tells me that the abstract deadline has been extended so go for it! There will be plenty of opportunities for ECRs to present 🧫🧬🔬🧪
add a skeleton here at some point
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reposted by
Thomas Clavel
Falk Hildebrand
8 months ago
Open postdoc position in my lab
@earlhaminst.bsky.social
@quadraminstitute.bsky.social
We will generate large-scale soil metagenomes to research the impact of agriculture on healthy soil microbiomes, developing strategies to increase carbon retention:
jobs.earlham.ac.uk/Details.asp?...
Please RT
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Very happy that HiBC is out:
rdcu.be/ekSCO
🔥
@natcomms.nature.com
Excellent team spirit, and, as always, great driving factor by
@tcahitch.bsky.social
⭐⭐⭐⭐ We hope that these bacterial isolates from the human gut will facilitate many studies by others... 😀
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HiBC: a publicly available collection of bacterial strains isolated from the human gut
Nature Communications - Here, the authors present and characterise a collection of human gut bacteria including novel taxa associated with health conditions and a large diversity of plasmids. All...
https://rdcu.be/ekSCO
8 months ago
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Thomas Clavel
NFDI4Microbiota
8 months ago
You’re invited to the 7th Community Workshop on 15 May 2025, 1-3 pm CEST! 🎉 Join NFDI4Microbiota for an exciting session of idea-sharing and collaboration. Find more info here :
tinyurl.com/yy2xjf2e
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reposted by
Thomas Clavel
NFDI4Microbiota
8 months ago
🚨 We're Hiring! Join our NFDI4Microbiota team at Friedrich Schiller University Jena as a Postdoctoral Researcher in Bioinformatics! 📍 Location: Jena, Germany. Apply here:
tinyurl.com/2mfm8y5b
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