Thomas Clavel
@tclavel.bsky.social
📤 158
📥 157
📝 13
Passoniate microbiome research; www.clavel.ukaachen.de
Interested in the design of defined microbial communities for fundamental research and applications? Hope this work & tool will help you 👇 As always
@tcahitch.bsky.social
has been a driving factor ⭐⭐⭐!
github.com/ClavelLab/Mi...
;
academic.oup.com/ismej/advanc...
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Validate User
https://academic.oup.com/ismej/advance-article/doi/10.1093/ismejo/wraf209/8256658?login=false
6 days ago
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Thomas Clavel
Emma Slack
13 days ago
Come and be my colleague at the Dunn School! It‘s a brilliant place to work and exciting to be building up our immunology team. Do apply. Do pass on the news 💉🧬🦠🔬🧫
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Thomas Clavel
NFDI4Microbiota
13 days ago
We’re heading to Jena for two exciting events! 📍 DGHM 2025 – 24 Sept Workshop: Data madness: Navigating Host Microbiomes Featuring VirJenDB – virus sequence discovery & analysis Details 👉
programme.conventus....
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Thomas Clavel
Steven Salzberg
20 days ago
We're still not finding any good evidence for a microbiome in any cancer type: see our new paper in @ScienceTM led by PhD student Yuchen (Peter) Ge
www.science.org/doi/10.1126/...
and the accompanying news piece,
www.science.org/content/arti...
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Comprehensive analysis of microbial content in whole-genome sequencing samples from The Cancer Genome Atlas project
An analysis of TCGA whole-genome sequencing samples yields a comprehensive resource for investigating the role of microbes in cancer.
https://www.science.org/doi/10.1126/scitranslmed.ads6335
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Carolin Wendling
20 days ago
Interested in exploring prophages in your (meta)genomes, but don't know how and where to start? We've put together a beginners guide to exploring viral diversity in prokaryotes
@marievasse.bsky.social
@sebwielgoss.bsky.social
@oxunipress.bsky.social
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Thomas Clavel
NFDI4Microbiota
about 1 month ago
Planning, sequencing… and now analysis. 📊 ☕ Coffee Talk: Getting Your Microbiome Research on the Road – Managing Your Data using Qiita 🗓️ Aug 25, 2025 | 14:30 CEST 👉 More info:
tinyurl.com/2m9jpf2p
👉 Workshop (Oct 22–24, Gießen):
tinyurl.com/4w8mczh7
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Thomas Clavel
Geraldine Zimmer-Bensch
about 1 month ago
🌍 Open Call! RWTH Aachen University invites postdocs from outside the EU to apply for the “Port to Europe” Fellowship (24 months funding, all disciplines). Start your research journey at one of Europe’s top universities! 🚀 Deadline: Oct 5, 2025. 👉https://rwth-aachen.de/go/id/botjje/lidx/1
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Thomas Clavel
Michael Zimmermann Lab
about 2 months ago
Do you have experience in metabolomics/lipidomics/exposomics? Check out the EMBL ARISE2 Fellowship Programme! 🔗
www.embl.org/training/ari...
📩 Contact: Juan Antonio Vizcaíno — Team Leader, EMBL-EBI 🔗
www.ebi.ac.uk/people/perso...
📌 Applications close soon! 📆 30/09/2025 More info below👇
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Thomas Clavel
Typas Lab
about 2 months ago
Ready to lead pioneering research that bridges systems-level investigations of biological systems to molecular mechanism? The EMBL Molecular Systems Biology Unit in Heidelberg is hiring a Group Leader!
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Group Leader – Molecular Systems Biology Unit
Are you ready to lead groundbreaking research in Molecular Systems Biology? Join us at EMBL! We are seeking a motivated scientist to lead an independent research group, addressing original biological ...
https://embl.wd103.myworkdayjobs.com/en-US/EMBL/details/Group-Leader----Molecular-Systems-Biology-Unit_JR2062
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Thomas Clavel
Lisa Maier Lab | Tübingen
2 months ago
Finally online! Our latest research is out
@nature.com
: We show that non-antibiotic drugs can disrupt colonization resistance, raising the risk of enteric infections.
rdcu.be/ewwrG
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Non-antibiotics disrupt colonization resistance against enteropathogens
Nature - Non-antibiotic drugs from a wide range of therapeutic classes can alter the ability of gut commensals to resist invasion by enteropathogens, a previously underappreciated side effect of...
https://rdcu.be/ewwrG
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François Leulier
2 months ago
A pure « délice » to have followed this story unfolding under our eyes. Congrats
@ameliejoly.bsky.social
brilliantly followed-up by
@lucasrebiffe.bsky.social
.
@filipedevadder.bsky.social
and I were/are so lucky to work with gifted Ph’D candidates like you!
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Thomas Clavel
NFDI4Microbiota
3 months ago
Try cloud-based microbiome workflows with CloWM—no installation needed! 📍 4th NFDI4Microbiota Annual Conference |Cologne 📆 Oct 2 | Registration is free 🔗
events.hifis.net/eve...
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Congrats
@baerboletta.bsky.social
👏 Highly deserved & best possible ambassador for the field
www.embo.org/press-releas...
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Outstanding life scientists elected to the EMBO Membership – Press releases – EMBO
Sixty-nine new members join the community of leading life scientists in Europe and beyond
https://www.embo.org/press-releases/outstanding-life-scientists-elected-to-the-embo-membership/
3 months ago
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Thomas Clavel
Nature Microbiology
3 months ago
#NewResearch
🚨Out now! Human gut bacteria bioaccumulate forever chemicals, in intracellular aggregates and colonization of gnotobiotic mice with these bioaccumulating bacteria increases faecal PFAS excretion.
@kiranrpatil.bsky.social
#MicroSky
#MicrobiomeSky
🦠
www.nature.com/articles/s41...
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Human gut bacteria bioaccumulate per- and polyfluoroalkyl substances - Nature Microbiology
Human gut bacteria bioaccumulate per- and polyfluoroalkyl substances (PFAS), commonly known as forever chemicals, in intracellular aggregates. Colonization of gnotobiotic mice with bioaccumulating bac...
https://www.nature.com/articles/s41564-025-02032-5?utm_source=bluesky&utm_medium=social&utm_campaign=nmicrobiol
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Thomas Clavel
NFDI4Microbiota
3 months ago
Join our NFDI4Microbiota Coffee Talk: Ivan Belyaev
@microverse.bsky.social
presents BEXIS2, a flexible platform for microbiology metadata. June 30 at 14:30 CEST. More info here:
tinyurl.com/mudhdnra
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Thomas Clavel
NFDI4Microbiota
3 months ago
🧫 Registration is open! Join the 4th NFDI4Microbiota Conference in Cologne 📅 Sept 30–Oct 2 | Theme: From Lab to Publication Hands-on workshops, keynotes, posters | Registration is free 📝 Register by Aug 31:
events.hifis.net/eve...
#FAIRdata
#Microbiome
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Thomas Clavel
Noah Fierer
3 months ago
Hope this is useful - consensus statement "Guidelines for preventing and reporting contamination in low-biomass microbiome studies"
rdcu.be/er3Io
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Guidelines for preventing and reporting contamination in low-biomass microbiome studies
Nature Microbiology - In this Consensus Statement, the authors outline strategies for processing, analysing and interpreting low-biomass microbiome samples, and provide recommendations to minimize...
https://rdcu.be/er3Io
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Thomas Clavel
NFDI4Microbiota
3 months ago
The #NFDI4Microbiota Flex Funds Call 2026 opens June 16! Support for infrastructure, workflows, training & more in microbiology. Deadline: Aug 11. Details:
nfdi4microbiota.de/n...
#NFDI4Microbiota
#OpenScience
#FAIRdata
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Thomas Clavel
Lisa Maier Lab | Tübingen
3 months ago
Ever wondered why proton pump inhibitors raise the risk of C. diff infections? Is it due to pH shifts or direct antibacterial effects on the gut microbiome? We think it’s the pH. 🧪💡 Dive into Julia & Patrick’s new paper for the full story! 📖👇
#Microbiome
#PPI
doi.org/10.1080/1949...
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Proton-pump inhibitors increase C. difficile infection risk by altering pH rather than by affecting the gut microbiome based on a bioreactor model
Clostridioides difficile infections often occur after antibiotic use, but they have also been linked to proton-pump inhibitor (PPI) therapy. The underlying mechanism – whether infection risk is due...
https://doi.org/10.1080/19490976.2025.2519697
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Thomas Clavel
Westermann Lab
3 months ago
Our latest:
www.cell.com/cell-reports/fulltext/S2211-1247(25)00615-1
. Links Bacteroides cell size w/ gene expression. Protocol works even for single cells. 🦠 Shoutout to
@elisebor.bsky.social
,
@emmanuel-saliba.bsky.social
,
@lbarquist.bsky.social
,
@jorg-vogel-lab.bsky.social
, Till Strowig & KC Huang.
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Low-input RNA-seq suggests metabolic specialization underlying morphological heterogeneity in a gut commensal bacterium
Bornet et al. investigate the morphological heterogeneity of Bacteroides thetaiotaomicron cells observed both in laboratory culture and inside the mammalian GI tract. The authors show that cell size i...
https://www.cell.com/cell-reports/fulltext/S2211-1247(25)00615-1
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Thomas Clavel
Karina Xavier Lab
3 months ago
Call for our new PhD program is open. Come join one of our labs at Gulbenkian Institute for Molecular Medicine - Lisbon-Oeiras, Portugal. Help us spread the word
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Thomas Clavel
NFDI4Microbiota
4 months ago
Join NFDI4Microbiota as a participant for 2026–2031! Gain early access to tools, bilateral exchange via an early-career ambassador, and targeted support for ELNs, DMPs, SOPs & FAIR data. Apply by June 10, 2025:
www.nfdi4microbiota....
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Thomas Clavel
Karina Xavier Lab
4 months ago
Call for Group Leaders - Join us at GIMM, 7 days till the deadline!
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Thomas Clavel
Andreas Peschel
4 months ago
Join us in Tubingen as a Junior Research Group Leader if you do research on
#ESKAPE
pathogens and infections and are interested in the highly cooperative environment of
@dzif.bsky.social
and
@cmfi.bsky.social
! Please send your application or forward to colleagues!
uni-tuebingen.de/universitaet...
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Thomas Clavel
NFDI4Microbiota
4 months ago
📅 Save the Date: NFDI4Microbiota Annual Conference in Cologne, 29 Sep–2 Oct 2025! Free, open to all hands-on workshops & scientific talks on microbial data integration. Network and shape the future of microbiome research. Details coming soon!
#NFDI4Microbiota
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Thomas Clavel
BacDive
4 months ago
A new look for BacDive 🖥️🦠! We are excited to introduce the new BacDive design✨ and now invite all users to try it out. Tell us what you think, we look forward to your feedback! You can find it at 👉
beta.bacdive.dsmz.de
or by clicking the red “New Design” button on every BacDive page.
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Thomas Clavel
Paul Cotter
4 months ago
PLEASE SHARE We’re hiring a contract
#bioinformatician
(research officer) to analyse
#microbiome
data from an ongoing, exciting project focusing on preterm birth prevention with oral probiotics
topjobs-teagasc.thehirelab.com/LiveJobs/Job...
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Thomas Clavel
NFDI4Microbiota
4 months ago
New training alert! 🚨 NFDI4Microbiota & DZIF offer an Intro to R online course (June 23–25, 2025). Ideal for beginners in R & bioinformatics. Apply by June 6:
events.hifis.net/eve...
#RStats
#OpenScience
#Microbiome
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Impressive lineup of speakers 🔥 In a nice city 😄 Do not miss the opportunity 🤙
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5 months ago
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Thomas Clavel
Emma Slack
5 months ago
This will be a fantastic meeting 👇🏻 A little bird tells me that the abstract deadline has been extended so go for it! There will be plenty of opportunities for ECRs to present 🧫🧬🔬🧪
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Thomas Clavel
Falk Hildebrand
5 months ago
Open postdoc position in my lab
@earlhaminst.bsky.social
@quadraminstitute.bsky.social
We will generate large-scale soil metagenomes to research the impact of agriculture on healthy soil microbiomes, developing strategies to increase carbon retention:
jobs.earlham.ac.uk/Details.asp?...
Please RT
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Very happy that HiBC is out:
rdcu.be/ekSCO
🔥
@natcomms.nature.com
Excellent team spirit, and, as always, great driving factor by
@tcahitch.bsky.social
⭐⭐⭐⭐ We hope that these bacterial isolates from the human gut will facilitate many studies by others... 😀
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HiBC: a publicly available collection of bacterial strains isolated from the human gut
Nature Communications - Here, the authors present and characterise a collection of human gut bacteria including novel taxa associated with health conditions and a large diversity of plasmids. All...
https://rdcu.be/ekSCO
5 months ago
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Thomas Clavel
NFDI4Microbiota
5 months ago
You’re invited to the 7th Community Workshop on 15 May 2025, 1-3 pm CEST! 🎉 Join NFDI4Microbiota for an exciting session of idea-sharing and collaboration. Find more info here :
tinyurl.com/yy2xjf2e
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Thomas Clavel
NFDI4Microbiota
5 months ago
🚨 We're Hiring! Join our NFDI4Microbiota team at Friedrich Schiller University Jena as a Postdoctoral Researcher in Bioinformatics! 📍 Location: Jena, Germany. Apply here:
tinyurl.com/2mfm8y5b
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Thomas Clavel
Nature Biotechnology
5 months ago
Enabling next-generation anaerobic cultivation through biotechnology to advance functional microbiome research -
@tclavel.bsky.social
@rwth.bsky.social
go.nature.com/3GA6gg4
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Enabling next-generation anaerobic cultivation through biotechnology to advance functional microbiome research - Nature Biotechnology
Overcoming key hurdles for the development of next-generation anaerobic cultivation methods could have major impacts on microbial community research and applications.
https://go.nature.com/3GA6gg4
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Here we share thoughts on next-gen cultivation:
rdcu.be/ejPSb
. Hope it helps 😄 Was fun to write with great colleagues
@lisamaierlab.bsky.social
@jselkrig.bsky.social
@baerboletta.bsky.social
@typaslab.bsky.social
@mmmicrobiomelab.bsky.social
@leibniz-dsmz.bsky.social
@westermannlab.bsky.social
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Enabling next-generation anaerobic cultivation through biotechnology to advance functional microbiome research
Nature Biotechnology - Overcoming key hurdles for the development of next-generation anaerobic cultivation methods could have major impacts on microbial community research and applications.
https://rdcu.be/ejPSb
5 months ago
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Thomas Clavel
NFDI4Microbiota
5 months ago
Don´t miss our coffee talk today!
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Thomas Clavel
Melanie Blokesch
5 months ago
Join the Blokesch lab (@EPFL) as a postdoc in Molecular Microbiology 🤩 Study Vibrio cholerae defense systems (phage/plasmid) in a dynamic, collaborative environment in Lausanne close to Lake Geneva in 🇨🇭! Please visit my lab's webpage for details about the position and how to formally apply.
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Thomas Clavel
The Dunn School, Oxford
6 months ago
Congratulations to Emma Slack and her group
@mucosalimmunology.bsky.social
@dunnschool.bsky.social
Game changing new approach to reducing antibiotic use and developing oral vaccines against major pathogens
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... and don't miss the opportunity to meet
@jeremyjbarr.bsky.social
and other great speakers at the upcoming Seeon Conference in June ⭐⭐⭐⭐⭐
www.dghm.org/seeon/
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5 months ago
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Thomas Clavel
Falk Hildebrand
6 months ago
Only a few days left to apply for our PhD position
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Thomas Clavel
Fatima Pereira
6 months ago
Check out this great
#PhD
opportunity at our School and join our growing
#Microbiology
team 👇
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Thomas Clavel
Laure Bindels
6 months ago
New editorial at Microbiome 🦠 ! Co-authored by the Senior Editors, it aims to highlight current challenges in the field of environmental and host-associated microbiome research and provides a blueprint for contemporary studies of the microbiomes.
microbiomejournal.biomedcentral.com/articles/10....
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A blueprint for contemporary studies of microbiomes - Microbiome
This editorial piece co-authored by the Senior Editors at Microbiome aims to highlight current challenges in the field of environmental and host-associated microbiome research. We also take the opport...
https://microbiomejournal.biomedcentral.com/articles/10.1186/s40168-025-02091-0
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Here the Senior Editors at Microbiome share their thoughts on current challenges and misconceptions in microbiome research 🤗
doi.org/10.1186/s401...
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A blueprint for contemporary studies of microbiomes - Microbiome
This editorial piece co-authored by the Senior Editors at Microbiome aims to highlight current challenges in the field of environmental and host-associated microbiome research. We also take the opport...
https://doi.org/10.1186/s40168-025-02091-0
6 months ago
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Thomas Clavel
The Dunn School, Oxford
6 months ago
New study by
@mucosalimmunology.bsky.social
(Dunn School and
@ethzurich.bsky.social
) with Médéric Diard (
@biozentrum.unibas.ch
) reveals how combining vaccines with friendly bacteria can boost vaccination efficacy and potentially reduce reliance on antibiotics
www.path.ox.ac.uk/news-article...
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Boosting vaccines with harmless bacteria to fight intestinal pathogens - Dunn School
Published in Science, a ground-breaking study by the Slack group reveals how combining vaccines with friendly bacteria can boost vaccination efficacy and potentially reduce reliance on antibiotics.
https://www.path.ox.ac.uk/news-article/boosting-vaccines-with-harmless-bacteria-to-fight-intestinal-pathogens/
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Excellent work by
@tcahitch.bsky.social
⭐ and there is even more to come very soon... 🔥
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6 months ago
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Thomas Clavel
Tom Hitch
6 months ago
Ever wondered if we are correctly predicting proteins from metagenomes? If so, we are happy to present our new work improving the prediction of proteins from the human gut microbiome:
www.nature.com/articles/s41...
! We corrected how each taxon's proteins are predicted and found WAY more proteins!
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Lineage-specific microbial protein prediction enables large-scale exploration of protein ecology within the human gut - Nature Communications
Microbes within the gut vary in how they encode genes, both in terms of the genetic codes and gene structures, which are often unexplored in metagenomic analysis. Here, the authors develop a lineage-s...
https://www.nature.com/articles/s41467-025-58442-w
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Thomas Clavel
Feargal Ryan
6 months ago
Delighted our study (7+ years in the making) is out today in Nature. In a nutshell, 48 hours of antibiotics in week 1 led to impaired vaccine responses up to 15 months later in infants. We show (in-vivo) a probiotic can fix it
#microbiome
#science
#immunology
www.nature.com/articles/s41...
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Bifidobacteria support optimal infant vaccine responses - Nature
Neonatal antibiotic use is shown to reduce immune response to infant vaccines, accompanied by reduced abundance of Bifidobacteria in the gut microbiota, with experiments in mice indicating that probio...
https://www.nature.com/articles/s41586-025-08796-4
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New preprint !🔥! By our next rising ⭐
@treichelnicole.bsky.social
with
@tcahitch.bsky.social
. Mock communities are helpful to benchmark methods in microbiome research. Species and strain diversity with metagenome-assembled genomes is inflated 😮:
www.biorxiv.org/content/10.1...
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Benchmarking of shotgun sequencing depth highlights strain-level limitations of metagenomic analysis
Shallow metagenomics promises taxonomic and functional insights into samples at an affordable price. To determine the depth of sequencing required for specific analysis, benchmarking is required using...
https://www.biorxiv.org/content/10.1101/2025.03.27.645659v1
6 months ago
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Thomas Clavel
Guillaume Méric
6 months ago
With no obvious causes and consequences, infantile colics can still be very distressing for parents. Here, authors suggest a gut microbiota contribution to colic in >1000 infants in KOALA cohort + higher levels of milk HMOs linked to less early constipation. 🔗
www.tandfonline.com/doi/full/10....
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Why do babies cry? Exploring the role of the gut microbiota in infantile colic, constipation, and cramps in the KOALA birth cohort study
Gastrointestinal symptoms are common during infancy, including infantile colic. Colic can be loosely defined as prolonged and recurrent crying without obvious cause. The cause indeed remains unclea...
https://www.tandfonline.com/doi/full/10.1080/19490976.2025.2485326?af=R
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