Can your brain's white matter proxies of inflammation re-identify you like a fingerprint? Turns out: yes, and we used this to psychometrically evaluate diffusion basis spectrum imaging and to detect depression-related changes in the cingulate bundle. #neuroskyence 🩺 www.medrxiv.org/content/10.6...

Super proud of @sjoerdmeijer.bsky.social who demonstrated that amygdala-TUS slows initial threat acquisition and enhances subsequent extinction. Great collaboration with @lennartverhagen.bsky.social and @deVoogdld.bsky.social ea. Thanks to @ERC.europa.eu. www.science.org/doi/10.1126/...

A teaser for our upcoming preprint on the short-term test-retest reliability of diffusion basis spectrum imaging. Voxel-level reliability of hindered fraction (a proxy measure of edema) in white matter is good, particularly close to cortical gray matter. W/ @lhkal.bsky.social @akuehnel.bsky.social

I am enjoying a few uninterrupted hours of plotting today. Finally got my hands on our diffusion basis spectrum imaging data, and it looks good, particularly in white matter voxels. I hope we will have a preprint coming out in a few weeks, led by @lhkal.bsky.social & @akuehnel.bsky.social

Thoroughly enjoyed writing a commentary on a great paper by @hugofleming.bsky.social et al for @biologicalpsych.bsky.social:GOS, focusing on how to further explore metabolic contributions to learning and feeling using real-time data and interventional designs: www.sciencedirect.com/science/arti...

Thanks to Deanna Barch for the opportunity to write this and @akuehnel.bsky.social for her thoughts on the first draft! And check out @hugofleming.bsky.social's paper for an exciting blend of computational psychiatry & real-time metabolic monitoring: www.sciencedirect.com/science/arti...

Pupil dilation is an established biomarker of arousal, and studies have shown that non-invasive vagus nerve stimulation (taVNS) elicits pupil dilation. Here, we find that it depends on sensory matching. #neuroskyence 🩺 Now published in @cp-iscience.bsky.social www.cell.com/iscience/ful...

Diese Woche berichtet @glassybrain.bsky.social u.a. vom Vagus und von vielen anderen spannenden Neuroscience Themen auf @realscientists.de ! Schaut mal vorbei 🔥

main goal for this year: find a new job! 🙂 looking for a role with fun & complex technical challenges & within a great community. my main expertise is in signal processing/EEG/MEG, but topic-wise I am quite flexible. science/industry both great! starting mid-year. nschawor.github.io/cv

Want to get the data out of a PDF figure? As in, the actual data – not a rough trace-along-the-lines version? I made an app you might like: adamkucharski.github.io/pdf2plot/ It all started a few years ago... 🧵

📣 Happy to share that our paper with Johan Vegelius is published! Title: “Developmental differences in reward-learning and its connection to resting-state functional connectivity modeled using a hierarchical Bayesian model” Find the full paper here: pubmed.ncbi.nlm.nih.gov/41478440/

Please spread the word🔊My lab is looking to hire two international postdocs. If you want to do comp neuro, combine machine learning and awesome math to understand neural circuit activity, then come work with us! Bonn is such a cool place for neuroscience now, you don't want to miss out.

Spent some time today playing around with the #Rstats package orchaRd 2.0 It offers a really nice way of visualizing #metaanalysis, especially moderator meta-regression models (with both categorical & continuous moderators!) #dataviz 🔗 daniel1noble.github.io/orchaRd/ 📄 doi.org/10.1111/2041...

Postdoctoral research position in #ComputationalPsychiatry and #EEG as part of relmed.ac.uk trial testing reinforcement learning as biomarker for antidepressant treatment response. www.ucl.ac.uk/work-at-ucl/... @uclbrainscience.bsky.social @mikebrowning.bsky.social @relmed.bsky.social

I have an early Christmas present for you! 🎅 Happy to announce that we have three excellent keynote speakers at Psychology and Brain 2026 in Heidleberg! Professors Shamay-Tsoory, Schönauer and Allen will cover topics from empathy over memory to interoception! pug2026.org

Ever wonder how you read so fast? Your brain gets a head start—processing the next word before your eyes move. Our MEG + eye tracking study out in Nature Communications study from @thechbh.bsky.social reveals orthographic & semantic previews predicting reading speed www.nature.com/articles/s41...

fMRI signals “up,” but neural metabolism might be going “down.” In our @natneuro.nature.com paper, we demonstrate that about 40% of voxels with robust BOLD responses exhibit opposite oxygen metabolism, revealing two distinct hemodynamic modes. rdcu.be/eUPO8 funds @erc.europa.eu #neuroskyence 🧵:

Thrilled to share our paper is out now in @ebiomedicine.bsky.social 🥳 The interoception accuracy part is still my favorite 🤩 Have a look: www.thelancet.com/journals/ebi...

What started as a spinoff project for Madeleine's PhD became one of the most striking indications that glucose levels play an important role in regulating everyday stress responses. This shows the potential of biosensors to evaluate whether metabolism alters stress reactivity #neuroskyence 🩺

📣I’m excited to share our new preprint on how our body’s energy supply shapes everyday stress experiences: 📄𝐇𝐢𝐠𝐡𝐞𝐫 𝐠𝐥𝐮𝐜𝐨𝐬𝐞 𝐥𝐞𝐯𝐞𝐥𝐬 𝐛𝐮𝐟𝐟𝐞𝐫 𝐚𝐠𝐚𝐢𝐧𝐬𝐭 𝐞𝐯𝐞𝐫𝐲𝐝𝐚𝐲 𝐬𝐭𝐫𝐞𝐬𝐬 𝐥𝐨𝐚𝐝 www.biorxiv.org/content/10.6...

Your stomach called – your striatum picked up! But does this actually happen in humans? Using simultaneous dopamine PET/fMRI, we show that the gut hormone ghrelin helps the brain adjust motivation to current metabolic need. Here’s what we found👇 Preprint: shorturl.at/pq4A3 #neuroskyence #🩺

Out now in @ebiomedicine.bsky.social 🚨. Hunger often affects our mood, but is this a conscious or a subconscious process? Using continuous glucose monitoring, we show that differences in mood are driven by hunger ratings, not just glucose. #neuroskyence 🩺 www.thelancet.com/journals/EBI...

Please share! - 🚨⚠️ PhD position alert ⚠️🚨 - Please share! Come work with @ldeserno.bsky.social and yours truly on an exciting DFG-funded project on the neurocognitive mechanisms of (noise in) learning and decision-making in development and ADHD!

There are 3 Oxford-based post doc positions for this Wellcome Trust project that will be advertised soon! If you have experinece in neurostimulation (tms/tus) and/or modelling of cogneuro data in humans do contact one of us (me, @mkflugge.bsky.social @lilweb.bsky.social, Jacinta OShea) to discuss!

Really excited about this 5-year project starting, funded by @wellcometrust.bsky.social, where we will combine ✨computational modelling✨ with causal intervention techniques such as ✨tFUS✨ to study the neurocognitive mechanisms of repetitive negative thoughts 🚀 led by @mikebrowning.bsky.social

First up, this paper led by Bronagh McCoy: journals.plos.org/ploscompbiol... When noise and volatility are independently manipulated people behave differently depending on their anxious traits.

Happy to say that our overview of how to modify your taVNS setup for safe use in the MR scanner is now published! dx.doi.org/10.1111/jon.... There are more details in the thread below but next to lower temperatures 🌡️, we also saw better signal-to-noise ratio with the modification 📶 #neuroskyence

I am pleased to announce that our new book on "Decision Making: Fundamentals and Applications" is now published by @springernature.com ! A collection of 17 chapters over 325 pages on #DecisionMaking #Psychology #Philosophy #Psychiatry @carstenmurawski.bsky.social link.springer.com/book/10.1007...

🔈 Our edited volume "Decision Making: Fundamentals and Applications", co-edited with @ulrichettinger.bsky.social and Bert Heinrichs, is out. url.au.m.mimecastprotect.com/s/9P5mCROAEn... #DecisionScience #DecisionMaking #Psychology #Psychiatry #Neuroscience #Philosophy

📆Save the date: new lecture series [1/4] This Wednesday, October 29 at 1 p.m., we are launching a new, hybrid series of guest talks organized the Center of Artificial Intelligence and Neuroscience (CAIAN) in Bonn.

My first post into the bsky void, the first preprint of my PhD! A novel task to bridge learning and effort decision-making. Of course, we find that effort choice is sensitive to prior learning, but this integration of beliefs into action is affected by anhedonia. doi.org/10.1101/2025...

📣 Excited to share that my first paper is now published! 📄"Metabolic state shapes cortisol reactivity to acute stress: A systematic review and meta-analysis of metabolic and hormonal modulators" You can find the full paper here: doi.org/10.1016/j.yn...

So glad to have been part of the #ECNP2025 conference! It was a great opportunity to present my poster on how different oral contraceptive states affect physiological and neural stress reactivity, and discuss new perspectives on mental health and well-being 🧠

1st Sharp Lab preprint! 🚨 We tested how anxiety affects task generalization—not how people generalize threat stimuli, but how they reuse action-outcome structures when planning in new contexts. Worry makes people avoid reusing actions that co-occurred w/ threat! 📄: osf.io/preprints/ps... 🧵 1/12

Published now (after long last & 10 citations). Although tVNS does not alter food reward ratings in healthy people, it acutely improved liking ratings in patients with MDD (also correlated with anhedonia). #neuroskyence 🩺 Work w/ @akuehnel.bsky.social www.sciencedirect.com/science/arti...

** We have up to TWO funded PhD positions available in our lab!! Apply below to find new ways to enhance memory👇 Pls retweet ** Deadline: 2nd December 1. Cross-species closed-loopTMR: tinyurl.com/bddu4tp6 2. TUS and TMR in humans: tinyurl.com/jjws5ctj Happy to chat to interested applicants.

Second day of the conference of Experimental endocrinology in Freising! 🥨 Really enjoyed the talk by Henrik Oster on circadian appetite regulation which gave a lot of food for thought: should I really give this dessert in the evening a go? 💭

I came across a terrific interview with Peter Dayan, always a delight to listen to. Peter's speed of mind and talk is possibly unsurpassable. www.youtube.com/watch?v=Cttx...

What drives the bidirectional relationship between metabolic and mental ill-health? Read our new metabolic psychiatry paper, “An interoceptive model of energy allostasis linking metabolic and mental health” www.science.org/doi/10.1126/... led by @saramehrhof.bsky.social @hugofleming.bsky.social

Please RT 2 new positions in the lab as postdoc & PhD! Interested in stress, pain, or reward? This project has it all! We are a friendly but ambitious group. Oslo is a capital city on the fjord & bordered by forest, great urban & outdoors opportunities: 💃 ⛷️ 🚣 🎭 🎶 www.jobbnorge.no/en/available...

Mental and metabolic health are closely linked - but what drives this connection? In our new theory paper, we (w/ @camillanord.bsky.social & @hugofleming.bsky.social g.bsky.social) propose dysregulation of interoceptive energy allostasis as a key mechanism. www.science.org/doi/10.1126/... 🧵 1/n

Big congrats to Marishka on this. I know how much time and effort went into it. Really happy to see it out! For those interested, she replicated prior longitudinal results using an approach-avoidance conflict task and showed how model parameters afforded out-of-sample clinical prediction.

New qualitative paper! A foray into gastric interception. @lucysta02475610.bsky.social ran a LOT of focus groups, across groups with eating disorders, gastric disorders and neither, to understand how people experience the sensations from their GI system. www.sciencedirect.com/science/arti...

In our new paper 📖🔥, we conducted a pooled analysis (n=443; 5 studies) to test if state affect (momentary mood) or trait dispositions (approach/avoidance) predict cortisol reactivity beyond biological & contextual factors. (1/4) #neuroscience #Neuroskyence #cogpsyc #AffectSci #psychscisky

We recently reported higher variability of reinforcement learning in obesity and BED, but what about neural representations? In our new preprint, we show higher variability in NAcc responses to reward cues in obesity and disinhibited eating www.medrxiv.org/content/10.1... w/ @nbkroemer.bsky.social

When we encounter the same reward repeatedly, we show variable responses; is this just noise? In our new preprint, we replicate the association of BMI and disinhibited eating with variability of NAcc signals to reward. #neuroskyence 🩺 W/ @akuehnel.bsky.social www.medrxiv.org/content/10.1...

The German government is investing €120 million in expanding the German Center for Mental Health (DZPG). Glad to join Thomas Nickl-Jockschat @jockschat.bsky.social and Daniela Dieterich with our project on cognitive flexibility and uncertainty in mental health. www.dzpg.org/aktuelles/pr...

Continuing the general thread, Peter Dyan does a very nice summary of Berridge's liking/wanting distinction, the evidence for it, and how it links to RL and interoception here (21:30): www.youtube.com/watch?v=vLA7...

One of the last projects of my PhD looking into insular functional segregation in depression is finally out as a preprint 🙏👇 Have a look and let us know what you think! #neuroskyence

If you are interested in using functional neuroimaging and neuromodulation to improve key symptoms of depression, we are still looking for PhD students: Official ad (in German, B2 level or better is required): karriereamukb.de/jobs/doktora...