Roche is seeking a Lead Clinical Director, Neurology. To Lead late-stage trials for Trontinemab in Alzheimer’s, shape strategy, and make real-world impact in a supportive, inclusive culture. Closing date: 3rd October www.dementiaresearcher.nihr.ac.uk/job/clinical...

🤩 JOB ALERT 🤩 Come work with me and two cutting-edge LC-MS/MS systems at our brand new Mass Spectrometry Facility @iimcb.bsky.social in Warsaw! Apply here tinyurl.com/y47mzafa or send any questions my way. #TeamMassSpec please share widely!

Perspectives in Computational Mass Spectrometry: Recent Developments and Key Challenges chemrxiv.org/engage/... --- #proteomics #prot-preprint

#AAIC2025 Today, Tuesday, July 29th, I am presenting my poster “Sex-specific associations between age-related blood proteins, cognition and Alzheimer’s biomarkers” (N. 364) Thanks to my supervisors and collaborators who made this work possible. @marcsuarezcalvet.bsky.social @fanastasi.bsky.social

📍Day 1 at #AAIC25 kicks off with strong participation from the #BBRC! Have a look at today’s schedule!! ⤵️ We'll keep you posted! @alzassociation.bsky.social

Early detection and effective treatment of neurodegenerative diseases remains one of the great scientific and medical challenges of the 21st century. Read our latest piece of news: www.barcelonabeta.org/en/news/news... @marcsuarezcalvet.bsky.social @natvilortejedor.bsky.social @fanastasi.bsky.social

Enrichment of extracellular vesicles using Mag-Net for the analysis of the plasma proteome www.nature.com/artic... --- #proteomics #prot-paper

I'm extremely happy to share that I've been awarded the @brightfocus.bsky.social Postdoctoral Grant! 🎉🙌 Huge thanks to BFF for their trust, and heartfelt gratitude to my mentors @marcsuarezcalvet.bsky.social and @bettytijms.bsky.social for their trust and help every step of the way! 💪✨

🎉 Great news!! Dr. @fanastasi.bsky.social has been awarded a prestigious research grant from the @brightfocus.bsky.social‬ to advance personalized approaches to #Alzheimer’s disease. Her project is one of 50 selected globally this year⤵️ www.barcelonabeta.org/en/news/news...

Please RT: In my lab we are looking for computational #postdoc researchers to apply to a #juandelacierva or #embo postdoctoral fellowships to work on projects on post-transcriptional regulation on single-cell data (method development and/or data analysis). Contact me if you are interested!

Are You Hiring? Let the US HUPO community know you're looking for a talented proteomic scientist! Post your job here: us-hupo.org/US-HUPO-... Looking for a job? Check out the job board! #ProteomicsJobs

A human protein tissue specifity atlas attempt that is actually good! proteomicsnews.blogspot.com/2025/04/a-ti... - punchline might be that there aren't all that many linear protein sequences that are tissue specific. Proteoforms are probably the only correct answer.

New manuscript alert! Can blood-based biomarkers measured on a fully automated platform accurately identify Alzheimer’s disease (AD) pathology?🩸 Our new multi-cohort study has now been published in @naturemedicine.bsky.social: nature.com/articles/s41.... A thread🧵

Had a great time today at #ADPD2025 presenting our research on global and sex-specific predictors of cognitive changes in preclinical AD. Huge thanks to my amazing colleagues for their incredible support! #proteomics #BarcelonaBeta #ALFAstudy

Excited to present at the Alzheimer's Insight Summit Industry Symposium at #ADPD2025! Grateful to #ADDI team for the invitation to share how my team leverages the AD Workbench to advance our research. Huge thanks to all partners for the great initiative! #ADresearch

Great #ADPD2025 #Forum02 on #integrating #bloodbasedbiomarkers w #CSF #imaging and #digital chaired by @melissamurray and @oskarhansson

Fantastic presentation by our amazing team member #PatriciaGenius, brilliantly showcasing epidemiological and genetic risk factors of regional white matter hyperintensities using strong statistical methods for profile selection! #ADPD2025 #NBGteam 🧠🧬

If you’re looking to gain hands-on training in the basics of mass spectrometry and proteomics bioinformatics, then this course is for you! Make sure you’ve submitted your application by 6 April: www.ebi.ac.uk/training/eve... Some financial assistance is available - see the course website. 🧪🧶🧬🖥️

36,000 plasma proteomes by mass spectrometry? No nanoparticles?!?! 2,000 protein depth? Can NOT wait to read this. proteomicsnews.blogspot.com/2025/03/pca-...

Unbelievable. This is just insane. What can we do from Europe to support this and other research projects being shut down in the USA? Scientists shouldn't have to fight for keeping knowledge alive but apparently they should start to.

Join us on March 21st for a primer on GWAS in AD and a great discussion with leaders in the field 🧠 🧬

DIA-NN 2.0 is released! We consider it the biggest step forward in the history of DIA-NN. On modern LC-MS almost all identifications are now peptidoform-confident, with major improvements e.g. for phospho. Some other cool things too: github.com/vdemichev/Di...

If you're a researcher impacted by the NIH/CDC/FDA travel and communication pause and are open to chatting about your experience, big or small, please reach out to me at [email protected] or DM for Signal

In an unprecedented move, research-grant reviews have been suspended indefinitely at the world’s largest public funder of biomedical research https://go.nature.com/4gc0Bc5

Finally, it is out!:) #SCP #Astral #massspectromentry www.nature.com/articles/s41...

Here are my book recommendations for the new year: Read the books you already bought.

New work from our postdoc Elouise Koops just got published: #locuscoeruleus metabolism is elevated in preclinical Alzheimer’s disease, and provides resilience against cognitive decline! In collaboration with Joyita Dutta (UMass) alz-journals.onlinelibrary.wiley.com/doi/10.1002/...

2 new studies on brain aging with sex-specific findings —Angiogenesis factors www.science.org/doi/10.1126/... —Loss of gray matter press.psprings.co.uk/jnnp/novembe...

Exciting new discovery from colleagues @stanfordmedicine.bsky.social, astrocyte metabolism compromised by amyloid and tau oligomers leading to insufficient support for neurons. Possible new target for treating AD. www.science.org/doi/10.1126/...

I am giving a 2-day #advanced #course on #astrocyte multiscale #models at the University of #Padua IT on April 10--11, 2025 #EMBO. An excellent opportunity to learn how to include #neuron-#glia #interactions in your models, from molecules to networks. Info & Registration: tinyurl.com/yx3m6acy

Hope I'm the first to post this all time classic on this platform

The human proteomic revolution proceeds with high-throughput assessment, AI analytics, correlation with health and disease, drug interactions, biomarkers www.cell.com/cell/fulltex...

Somalogic, Olink, and Alamar are casting doubt on each other’s data, proudly calling out lack of correlation. I know why they do this but in the long run as it casts doubt on affinity approaches as a whole. We will think lots of data is generated that is trash and won’t know which

Paper of the year 2 👉 astrocytes, glucose, lactate, IDO1 and impressive results! 👇👇👇👇👇👇👇👇👇👇👇👇👇 www.science.org/doi/10.1126/...

Addressing statistical challenges in the analysis of proteomics data with extremely small sample size: a simulation study - BMC Genomics bmcgenomics.biomedce... --- #proteomics #prot-paper

New press release today featuring our manuscript that sets forth recommendations to make dementia research more inclusive. I am so happy to get this work into the scientific register. I am so proud to serve as senior author. #GSA2024 #geronsky www.alz.org/news/2024/pu...

#teamMassSpec here is a starting pack in case you just moved over, or in case you've been absent for a while. This is #proteomics or #massspec related. The pack is not comprehensive but it's a start. go.bsky.app/HH7kqEh