🧪To the science feed you go... if you like #neutrophil #metabolism #metastasis #UPP1 #Uracil #fibronectin, then you are in for a treat 👇

Our new preprint is out! Led by @stefanosala89.bsky.social sky.social we investigate the difference between molecular tension sensing and global tension on the focal adhesion. Follow along for a thread of our findings: www.biorxiv.org/content/10.1...

Latest from Ivaska Lab ▶️ Niklas Jäntti et al delve deep into the roles of EPLINα/β on integrin trafficking and breast cancer outcomes! Congratulations to all the authors! Check the paper out here: www.sciencedirect.com/science/arti...

Are you looking for a postdoc? I will be looking for 2-4 people after the summer to join the lab !! Do not hesitate to reach out and disseminate !!

1/ Beyond thrilled to see my #PhD work now published in @jcb.org A short thread (🧵) for #metastasis #metabolism #ExtracellularVesicles (EVs) aficionados

In a new study led by InFLAMES PI Professor Johanna Ivaska and Dr James Conway have developed a new fluorescent probe to visualise signaling dynamics in moving cancer cells which they used to uncover a new therapeutic possibility for limiting breast cancer spread. #Illusia @ivaskalab.bsky.social

New paper from @ivaskalab.bsky.social out now! 🍾 Watch how cancer cell adhesion dynamics are disrupted by inhibiting the phosphatase Shp2 - key to integrin β1 phosphorylation. Blocking Shp2 impairs adhesion and reduces invasion potential. 🎥👇 Read more at: www.nature.com/articles/s41...

Latest from @ivaskalab.bsky.social @jrwconway.bsky.social in NCB. We find that SHP-2 inhibition stops TNBC invasion and limits metastasis by blocking integrin dephosphorylation! Read more at: www.nature.com/articles/s41...

Excited to share our recently published study on how DNA secretion in neutrophils modulates their inflammatory response spearheaded by @sbarya.bsky.social Thanks to all our collaborators and contributors for their help getting this story to press. 👏👏 www.nature.com/articles/s41...

Paljon onnea Suomen tiedepalkinnosta, @johannaivaska.bsky.social Professorin viesti päättäjille: "Minä toivoisin, että Suomen valtiovalta ja poliitikot ymmärtäisivät, että pienessä maassa perustutkimus on se ainoa tapa, millä niitä paljon puhuttuja innovaatioita saadaan." www.ts.fi/uutiset/6665...

Here we share our opinions on "Practical considerations for data exploration in quantitative cell biology" journals.biologists.com/jcs/article/... Joanna, Hanna and I worked quite a bit on this piece and I hope you find it useful Many thanks to @jcellsci.bsky.social for publishing it

We are looking for a doctoral candidate to join the lab! If you are interested in working with human breast tissue samples straight from the clinic and do not fear large data sets, this might just be your dream project ☺️ Apply now ⬇️ ats.talentadore.com/apply/vaitos... 📸 @oonapaavolainen.bsky.social

Looking for EGFR shrna plasmid urgently if someone has it🙏 if you could please check your connections it would be great as well! Thank you

As scientist I am going through difficult times (this is understatement of the year for me!!). Past one and half months have been horrible, however I am trying to pick myself up and super excited to share my postdoc work with the community! #cellmigration www.biorxiv.org/content/10.1...

🚨 new preprint 🚨 Here we report that deleting the Septin aspB results in cidal activity of the static anti cell wall drug Caspofungin. This wasn’t only in vitro as 🐭 infected with the mutant and treated had 70% survival compared to 30% of the wild-type 1/2

I am very excited to (delayed) share our preprint which has been led by Kabilan Sakthivel on mechanisms by which ECM stiffening of normal 3D tissues in their native environment drives invasive phenotypes www.biorxiv.org/content/10.1...

If anyone happens to need it this week for...reasons...this is the best graphic on the complexity of human sex determination I've ever seen. I use it in an undergrad course on gene regulatory mechanisms. Shoutout to @unamandita.bsky.social! www.scientificamerican.com/article/beyo...

Trying something new: For our recent preprint: Fast label-free live imaging reveals key roles of flow dynamics and CD44-HA interaction in cancer cell arrest on endothelial monolayers www.biorxiv.org/content/10.1... I made an online presentation: www.beautiful.ai/player/-ODGe...

Here is the most recent preprint from our most recent PhD graduate, Dr Nicolas Pasquier. Orientation of mucinous CRC apicobasal polarity is regulated by tumor-stroma interactions. This work was a collaboration with the Jaulin lab at the Gustave Roussy Institute. www.biorxiv.org/content/10.1...

Latest from the lab: TLNRD1 is a CCM complex component and regulates endothelial barrier integrity. Many thanks to Neil, Sujan, Gautier, Ada and co for the hard work. Fantastic colab with Ben Goult www.biorxiv.org/content/10.1...