I'm happy to announce the latest release of the GlobDB, available at globdb.org. The GlobDB is a database of "species dereplicated" microbial genomes, and as of release 226 contains twice the number of species-representative genomes (306,260) than the latest GTDB release.

Bacteria rely on retrons for #phage defense, but most known systems come from clinical or lab strains. @seth-shipman.bsky.social &co identify diverse #retrons from environmental #bacteria, uncovering their defense mechanisms & using them as #GenomeEditing tools @plosbiology.org 🧪 plos.io/4oDqRAF

How are we replicating our #DNA? Find origin in the #Asgard #Archaea!

chromosome replicationists – #Archaea branch, Asgard dept. – take note 👇 #ArchaeaSky thx @acritschristoph.bsky.social for boosting this 🙏

Glad to share our paper out today @NatureEcoEvo: “Serial innovations by Asgard archaea shaped the DNA replication machinery of the early eukaryotic ancestor”. www.nature.com/articles/s41... #microsky #archaeasky

Latest #CDlab paper on @biorxivpreprint.bsky.social: Spatial control of karyopherin binding avidity in NPC mimics revealed by designer FG-Nucleoporins www.biorxiv.org/content/10.1... With experiments & MD simulations we study de novo designed proteins for selective transport through nuclear pores

It is the year of the (more?) complex prok multicellularity :)

Wow, I feel greatly honored by being awarded the 2026 Biochemical Society Award for Significant Breakthrough or Achievement, as was just announced! www.biochemistry.org/about-us/new... It is wonderful that the Biochemical Society honors our contributions to single-molecule biophysics in this way!

Sooo cool! Congrats @archaeon-alex.bsky.social and Co.!

We are looking for tenure-track and tenured biologists to join our department: School of Life Sciences at EITech Ningbo. It's a new private university, English taught, benefits and selection are both internationally competitive. Please apply & contact me if you have any questions. shorturl.at/Rjqku