New Issue Alert — mLife Vol. 4, Issue 6 is out! The issue features 10 open-access papers spanning host–pathogen interactions, bacterial cell division, RNA editing, phage therapy, CRISPR optogenetics, and more. Table of contents here 👉 onlinelibrary.wiley.com/doi/10.1002/... Highlights below ⬇️

Join the IC-DLI x mLife Webinar on Deep Life Studies! 🗓 Dec 30 | 🕐 13:00 UTC | 🧪 3 exciting talks on: • Deep-sea cold seep microbiomes • Novel methanogens beyond Euryarchaeota • Habitable rock–water systems 📍Zoom ID: 853 4219 3531 | PW: 904477

Come to follow the official BlueSky of the journal #mLife!

Insightful Review in #mLife! Emerging single-cell sequencing and imaging technologies now allow for the profiling of microbial heterogeneity with unprecedented resolution—capturing phenotypic and spatial diversity within microbial communities. 🔗 doi.org/10.1002/mlf2...

Discovery of rare #protist reveals previously unknown branch of eukaryotic tree of life phys.org/news/2025-11... Rare microbial relict sheds light on an ancient eukaryotic supergroup www.nature.com/articles/s41... #Protists #Microbes #Evolution #Eukaryotes #TreeOfLife

An archaeal genetic code with all TAG codons as pyrrolysine www.science.org/doi/abs/10.1... #jcampubs

An Asgard archaeon with internal membrane compartments Brilliant study led by @fmacleod.bsky.social and Andriko von Kügelgen. Tight collaboration with @buzzbaum.bsky.social and lab. Congrats to all authors! www.biorxiv.org/content/10.1...

Asgards everyday! Another boost to the metabolism at the prokaryote-eukaryote interface.

I'm happy to announce the latest release of the GlobDB, available at globdb.org. The GlobDB is a database of "species dereplicated" microbial genomes, and as of release 226 contains twice the number of species-representative genomes (306,260) than the latest GTDB release.

Bacteria rely on retrons for #phage defense, but most known systems come from clinical or lab strains. @seth-shipman.bsky.social &co identify diverse #retrons from environmental #bacteria, uncovering their defense mechanisms & using them as #GenomeEditing tools @plosbiology.org 🧪 plos.io/4oDqRAF

How are we replicating our #DNA? Find origin in the #Asgard #Archaea!

chromosome replicationists – #Archaea branch, Asgard dept. – take note 👇 #ArchaeaSky thx @acritschristoph.bsky.social for boosting this 🙏

Glad to share our paper out today @NatureEcoEvo: “Serial innovations by Asgard archaea shaped the DNA replication machinery of the early eukaryotic ancestor”. www.nature.com/articles/s41... #microsky #archaeasky

Latest #CDlab paper on @biorxivpreprint.bsky.social: Spatial control of karyopherin binding avidity in NPC mimics revealed by designer FG-Nucleoporins www.biorxiv.org/content/10.1... With experiments & MD simulations we study de novo designed proteins for selective transport through nuclear pores

It is the year of the (more?) complex prok multicellularity :)

Wow, I feel greatly honored by being awarded the 2026 Biochemical Society Award for Significant Breakthrough or Achievement, as was just announced! www.biochemistry.org/about-us/new... It is wonderful that the Biochemical Society honors our contributions to single-molecule biophysics in this way!

Sooo cool! Congrats @archaeon-alex.bsky.social and Co.!

We are looking for tenure-track and tenured biologists to join our department: School of Life Sciences at EITech Ningbo. It's a new private university, English taught, benefits and selection are both internationally competitive. Please apply & contact me if you have any questions. shorturl.at/Rjqku