There is still a widespread belief that fever is harmful and that it should be treated regardless of the underlying cause, which is not supported by clinical data. 🆕💫 Review: Fever in sepsis revisited: Is a little heat what we need? #idsky academic.oup.com/ofid/article...

When we care for PWH who have virologic suppression, but possible or confirmed NRTI resistance, can we switch them to a simple oral treatment -- once-daily BIC/FTC/TAF? This study says yes, with results strengthened by proviral DNA testing. #IDSky #HIVSky www.sciencedirect.com/science/arti...

Must read for all teams consulting infectious diseases #idsky #idmeded #meded #stewardship #voicesofID @cidjournal.bsky.social academic.oup.com/cid/advance-...

🏭 Manufacturers work with CLSI & FDA to stay aligned and update breakpoints efficiently. 🎙️ Hear Andrea Prinzi break it down on Let’s Talk Micro — brought to you by bioMérieux. 👉 Listen: asm.org/podcasts/let... #AST #Breakpoints #Microbiology #LetsTalkMicro #bioMérieux

Propensity-Matched Comparison of Timely vs. Delayed Antibiotic Therapy in Stenotrophomonas maltophilia Pneumonia ✅ Just Accepted ⭐ Editor's Choice #IDSky

Finally published 🆕🔥DOTS RCT Among participants with complicated S aureus bacteremia who achieved blood culture clearance, dalbavancin was not superior to standard therapy for achieving a more desirable outcome at day 70 #idsky jamanetwork.com/journals/jam...

DOTS trial is published! It will be interesting to see how data correlates with SNAP. jamanetwork.com/journals/jam... Thanks to @jonathanrydermd.bsky.social and @kenkoonwong.bsky.social for letting me know! #IDSky

Clinical consequences of delaying implementation of long-acting antiretroviral therapy for people with HIV and persistent viremia in the US ✅ Just Accepted ⭐ Editor's Choice #IDSky

Propensity-Matched Comparison of Timely vs. Delayed Antibiotic Therapy in Stenotrophomonas maltophilia Pneumonia ✅ Just Accepted ⭐ Editor's Choice #IDSky

⭐️ 📄 ⭐️ Recently @pharmermeg.bsky.social updated this open-access post. Originally published in 2017, the new version has a complete overhaul & provides a downloadable document. This is an article that has been read by by tens thousands of people 🌎🌍🌏. www.idstewardship.com/cross-reacti... #IDsky

I know RFK Jr. has assembled a quack crew to concoct a study showing otherwise but here is an new important large cohort study of over 1.2 million children in Denmark showing no association Aluminum adsorbed vaccines and chronic dz in childhood including autism. www.acpjournals.org/doi/10.7326/...

Taxonomy shift 🚨 Candida auris has been reclassified as Candidozyma auris (C auris ) to reflect its distinct genetic profile from other Candida species. #IDSky #microsky

Bactericidal vs Bacteriostatic Antibiotics. This controversial topic has important conceptual ramifications to treat severe infections. youtu.be/3z4BItBrzbk

1/ The first #ACIP meeting with RFK Jr.’s handpicked members wrapped up yesterday. Over 4,000 tuned in—a level of attention we haven’t seen since the pandemic. And for good reason: these meetings shape vaccine policy, coverage, timing, access and availability. Here's what happened 👇

RFK Jr.‘s extreme anti-vax views — and his related conflicts of interest — were a huge problem during his confirmation process. So he promised not to change the vaccine advisory panel. Today, he fired every single expert on that panel. It's a public health disaster.

Today more than ever I think it is important to remind ourselves that #ElonMusk led indiscriminate cuts which have resulted in the estimated deaths of over 300,000 people globally to date. 2/3rds of these are children!!! He is still very much a villain. www.impactcounter.com/dashboard?vi...

Um. 🤔Who could have known these citations were fake…🤷‍♀️ Kennedy R. Brain worms: Unlocking creativity and spontaneous bad ideas. Inst Fake Neurol 2024;42(3):123-124. Prasad M. COVID-19: Panic shopping and other pandemic benefits. Pandemics J. 2023;15(2):45-46. www.rollingstone.com/politics/pol...

Variability in Durations of Therapy for Gram-Negative Bloodstream Infections and Factors Associated with Prolonged Durations ✅ Just Accepted ⭐ Editor's Choice #IDSky

Happy infectious diseases pharmacist day 💊🧫🦠 love being able to advocate for AMS, ID DDI, and optimize cost effective therapy for our patients and institution! #IDPharmacistsDay #SIDPAdvocacy #FutureOfIDPharmacy #PharmacistsLeadingChange @sidpharm.bsky.social

Improved Detection of HIV-1 Drug Resistance with Droplet Digital PCR: A Comparative Study and Its Implications ✅ Just Accepted #IDSky

“Our study demonstrated associations between obesity, particularly severe obesity, and the incidence of 16 common health outcomes.” 📋 Read the full study results by Z. Yao et al. in NEJM Evidence: eviden.cc/4iIRjGg #MedSky #EndoSky

wow...and sad.

This week, rising tick-borne illnesses from warmer winters, strong hepatitis E vaccine efficacy during an outbreak, emerging fungal threats and resistance, and more from Contagion. #IDsky #MEDsky Read more: www.contagionlive.com/view/top-5-i...

In our Spring issue: From the discovery of penicillin to PK-PD principles: A brief historical overview and what we have learned from recent clinical trials. Dr. Alwin Tilanus writes on this topic. #IDsky #Medsky

🆕💫New Hope, New Threat: Ceftazidime/avibactam brought promise—resistance followed fast. England’s 4-year data shows why real-time surveillance and stewardship matter more than ever. A must-read #IDsky pmc.ncbi.nlm.nih.gov/articles/PMC...

Join us while we celebrate Asian Pacific American Heritage month! Visit asianpacificheritage.gov to learn more about events and exhibitions in your area.

jamanetwork.com/journals/jam... MVCs were associated with a significantly higher percentage of patients with VC-related adverse events or dysfunctions and could not be demonstrated as a noninferior alternative to PICCs.

I don’t usually post around this time—unless something 🔥 drops. Time zones don’t matter when it’s this good Worth breaking the pattern #IDsky #EMIMCC

Dear Canada- Please accept our deepest apologies from all decent Americans embarrassed by the obnoxious trolling from our man-baby-in-chief who is lacking in both intelligence & any impulse-control whatsoever. ❤️ from your neighbors below, 🇺🇸 #MakeAmericaNormalAgain

Fungal infections are rising globally, with new studies shedding light on antifungal resistance, deadly Aspergillus infections, & surprising Histoplasma findings. #IDsky #MEDsky Dive into the latest research from the CDC's Emerging Infectious Diseases: www.contagionlive.com/view/new-ins...

If it walks like a duck and quacks like a duck…

‘Birds of a feather’ RAPE children together…👇 Remember that.

“What stage of authoritarianism is it when the government starts arresting judges? Because that’s the one we’re at.” @atrupar.com

"Ideologic opposition to DEI and the very acknowledgment that race matters need not and should not interfere with the provision of excellent health care to individuals in need." Read this JAMA Perspective about DEI programs and academic medical centers. #MedSky ja.ma/3YPHI8S

A friend told me he was advised to remove the word "women" from his #NIH grant in order for it to be viewed more favorably. This administration is disgusting. #saveourscience

One of the most challenging encounters in the outpatient practice of infectious diseases, summarized here wonderfully in @cidjournal.bsky.social by Drs. Advani and colleagues. Have already used this algorithm several times! doi.org/10.1093/cid/...

Scientific Integrity Under Threat: The Role of the IDSA, PIDS, and SHEA Journals in an Evolving Political Landscape @cidjournal.bsky.social @jidjournal.bsky.social @ofidjournal.bsky.social @ichejournal.bsky.social @jpidsociety.bsky.social @ashejournal.bsky.social academic.oup.com/cid/advance-...

Rifaquizinone is a dual-pharmacophore antibiotic combining rifamycin and a fluoroquinolone-like compound, showing strong bactericidal activity against resistant S aureus strains and biofilms, with promising results for treating prosthetic joint infections but limited oral bioavailability. #IDsky

Cryptococcal Meningitis Treatment Beyond HIV: Recognizing the need for Individualized Immune-Based Strategies Hyunah Yoon, Liise-anne Pirofsky, @drboulware.bsky.social In non-HIV-associated CM, ⬇️ing immunosuppression --> ⬆️ inflammation --> 🧠 damage. academic.oup.com/cid/advance-... #TxID #IDSky

2 recent RCTs: ESCAPe MP ❌️ CAPE COD HC ✅️ ➕️ Meta-analyses ✅️ Now REMAP CAP ❌️ A 🔥 topic in critical care & ID #idsky #EMIMCC

Not gonna lie, I’m still wrapping my head around RAR (Response-Adaptive Randomization). Anyone have a simple breakdown? #idsky

Yep. Perfectly put. In essence, tyranny.👇

"We have come a long way in preventing disease through vaccination and we must not lose our progress." This Viewpoint discusses the importance of early and continued vaccine use in the US. #MedSky https://ja.ma/43ORfQZ

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Sign of the day…

Didn’t get a chance to post this earlier, but there was a huge turnout in support of Kilmar Abrego Garcia at the federal courthouse. From my seat in the jury room, I heard the supporters outside chanting throughout the hearing.