NEW in ICHE: modeling the impact of pathogen reduction on CRE BSIs and deaths in US ▶️ Used multiple healthcare facility types ▶️ Reduction of 69-75% of CRE BSIs if used in LTACH/vSNFs ▶️ 90% averted BSIs would have been in Pts w/o agent #IDSky 📄: doi.org/10.1017/ice....

NEW in ICHE: Local public health response to first Candida auris outbreak spanning 28 healthcare facilities 10 months in Arizona ▶️ 39 clinical cases ▶️ 17.6% (158/899) contacts colonized with C. auris ▶️ 9.5% (15/158) developed infection #IDSky 📄: doi.org/10.1017/ice....

New in ICHE: 4-year pseudo-outbreak of NTM Increase of M. mucogenicum in BAL (6.1% ▶️ 18.6%) --Non-sterile ice baths contaminated samples --No true infections --458 hours of FTEs --$88,426 of laboratory costs #IDSky 📄: doi.org/10.1017/ice....

New episode of The ICHE Podcast! Dr. Barbara Jones and Dr. Sheryl Kluberg discuss their recent publications that evaluate the impact of oral care and in-hospital mobility on non–ventilator-associated hospital-acquired pneumonia. Listen here: on.soundcloud.com/E8RR2No5ZT4u...

🆕 New in ICHE: Can we predict MDRO carriers on admission? A model using prior healthcare exposures (SNF, LTACH) had varying performance: ▶️ AUC = 0.76-0.82 for HAI-associated pathogens ▶️ AUC = 0.59, 0.61 for community-based pathogens #IDSky 📃: doi.org/10.1017/ice....

🆕 New in ICHE: Can LLMs help identify cardiovascular implantable device infxs? Researchers used LLM to review EMR notes & flag likely cases across 3 VA hospitals ▶️ High agreement w/ expert review ▶️ Manual adjudication still needed #IDSky 📃: doi.org/10.1017/ice....

Did you know you may be able to publish open access at no cost in SHEA’s journals? Check whether your institution has an open access publishing agreement with Cambridge using the eligibility checker: www.cambridge.org/core/eligibi...

NEW in ICHE: An interdisciplinary infectious disease support team with longitudinal process interventions is associated with lower 28-day mortality in bacteremia #IDSky 📄: doi.org/10.1017/ice....

New in ICHE: Clinical utility of serial plasma cell-free DNA metagenomic next-generation sequencing assays ▶️ Authors find that only 5/173 cases of serial plasma metagenomic next-generation sequencing had significant clinical impact #IDSky 📃: doi.org/10.1017/ice....

New in ICHE: Optimizing facility-specific urinary weighted-incidence syndromic antibiograms for nursing homes 🦠 5097 urine cultures from 59 nursing homes ➡️2 years weighted-incidence syndromic antibiogram (WISCA) = valid antibiogram #IDSky 📃: doi.org/10.1017/ice....

NEW in ICHE: Trends of bloodstream infection incidence rates among patients on outpatient hemodialysis, NHSN, 2012–2021 ⏫ facilities reporting BSI Rates: 2012-2020 ⏬ 8.9% 2020-2021 ❌ no change #IDSky 📃: doi.org/10.1017/ice....

New in ICHE: Risk factors for progression from Clostridioides difficile colonization (NAAT+/toxin–) to infection (toxin+) following symptomatic retesting High-risk antibiotics aOR 2.70 for CDI #IDSky 📃: doi.org/10.1017/ice....

New in ICHE: Healthcare worker long-sleeved attire contamination: a prospective observational study 280 samples: ▶️ 81.1% (n = 227) any bacterial growth ▶️ 20.7% (n = 58) ≥1 potential pathogen #IDSky 📃: doi.org/10.1017/ice....

New from @jonathanrydermd.bsky.social et al: Are SEP-1 and blood culture stewardship at odds? Retrospective review of SEP-1 failures pre- and during a blood culture bottle shortage BCs avoided without patient harm! #IDSky @kcawcutt.bsky.social 📄: doi.org/10.1017/ice....

Excited to share our latest publication about SEP-1 metrics during the BCx shortage in the setting of enhanced BCx stewardship efforts @kcawcutt.bsky.social @ichejournal.bsky.social #IDSky www.cambridge.org/core/journal...

New in ICHE: Racial disparities in antibiotic selection for community-acquired pneumonia in hospitalized patients #IDSky 📃: doi.org/10.1017/ice....

NEW in ICHE: Authors used a propensity-matched cohort to evaluate intermittent vs. continuous cefazolin for SSI prevention in cardiac/neuro procedures🧠❤️ ▶️ While non-significant differences, 0% SSI rate among cardiac surgeries + continuous infusion #IDSky 📄: doi.org/10.1017/ice....

NEW in ICHE: Investigation & control of an outbreak of MSSA SSTIs in a NICU ▶️ 16 MMSA infxs in 3 weeks + 31 colonizations ▶️ Multiple ST clusters <10 SNPs ▶️ Educational interventions ▶️ Suspect respiratory devises or adhesives #IDSky 📄: doi.org/10.1017/ice....

Our new paper out: AI boosted our genomic surveillance investigations by finding 37 missed transmission routes and reaching >90% sensitivity in key scenarios. AI + WGS can speed outbreak reviews and help IP teams act faster #IDSky Genomic surveillance is a key must! 📃: doi.org/10.1017/ice....

New in ICHE from @grod11.bsky.social et al: Using secure AI agents integrated within the EMR for the evaluation of blood culture appropriateness LLM agents showed: ▶️ High sensitivity (77.4%) ▶️ Low specificity (36.1%) ▶️ framing, sycophancy, & semantic cues vital #IDSky 📄: doi.org/10.1017/ice....

🆕 New in ICHE: Can we make VRE screening more efficient? Authors found: ▶️ VRE+ patients had recent high-risk antibiotic exposure ▶️ Using abx-guided screening = avoided 50% of tests ▶️ VRE+ rate = 5.6% w/ targeted vs 2.6% overall ▶️ Maintained 100% NPV #IDSky 📄: doi.org/10.1017/ice....

NEW in ICHE: Environmental and human health impact of contact precautions In LA County, contact precautions for MRSA/VRE: ▶️ Use 7.3 million gowns annually ▶️ Generate 506 tons of plastic waste ▶️ 1.73 million kgs of CO2 equivalents = -4.07 DALYs #IDSky 📄: doi.org/10.1017/ice....

NEW in ICHE by @pamipenem.bsky.social and others: Interprofessional Education (IPE) in Infection Prevention and Control (IPC): a helpful way to increase learner's confidence in IPC skills and acknowledge that teamwork does make the dream work #IDSky 📃: doi.org/10.1017/ice....

🆕 New in ICHE: Genomic epidemiology of HAI respiratory viruses in Pittsburgh, 2018–2020 🧬 WGS of 436 healthcare-associated respiratory virus infections: • 14 clusters ▶️ 36 patients • Clusters often in a single unit • Avg cluster duration 16 days (range 0-55) #IDSky 📄: doi.org/10.1017/ice....

New multisociety guidance from SHEA, APIC, IDSA, PALTmed & AGS offers an updated framework for infection prevention in nursing homes—balancing safety with a homelike environment. Read in ICHE: bit.ly/47vOSCV

🆕 New in ICHE: How prepared are Canadian hospitals for Candida auris? A CNISP survey of 55 hospitals found: --87.3% had C. auris on their notifiable/reportable pathogen list --70.9% used PCR for identification --30.9% reported C. auris cases between 2012–2022 #IDSky 📄: doi.org/10.1017/ice....

Now out in @ichejournal.bsky.social, our teaching elective that we put together while grant funding still existed--we made IP fun, and students gained confidence in their skills. <3 my team and am glad to see this out there! doi.org/10.1017/ice....

New multi-society implementation and practice recs for IPC in nursing homes. How to balance safety and home-like care. An essential resource for IPC program leaders with SHEA, APIC, IDSA, PALTmed, PIDS #IDsky 📄: doi.org/10.1017/ice....

🆕 New in ICHE: What drives repeat C. difficile testing? -Repeat testing within 7 days was (4.5%) across VA hospitals -Most repeat tests were negative (OR=3.62), canceled (OR=8.52) -More likely w/ residents, long-term care/ICU settings, & positive initial tests #IDSky 📄: doi.org/10.1017/ice....

Our EIC @davidcalfeemd.bsky.social giving an update to the @sheaepi.bsky.social publications committee at #IDWeek2025!

#IDWeek2025 - most cited papers in ICHE for 2025! Congrats and thank you to all the authors! #IDSky

🆕 New in ICHE: Mycobacterium fortuitum outbreak linked to two outpatient surgery centers. ▶️ 17 cases across 2 facilities ▶️ Most common procedure: knee replacement ▶️ Concerning gaps: delayed reporting, lack of certified personnel in IP and reprocessing #IDSky 📄: doi.org/10.1017/ice....

🆕 New in ICHE: Factors associated w/ HCP glove & gown contamination of MRSA Contamination: Gloves or gown: 713/3,832 (18.6%) of the time Gloves: 15.4% Gowns: 8.3% Touching: Patient: 622/2,901 (21.4%) Environment: 91/931 (9.8%) #IDSky 📄: doi.org/10.1017/ice....

🆕 New in ICHE: Can beard covers improve speech intelligibility while maintaining respirator fit? An under-mask elastic band beard cover with N95/P2 respirators found no meaningful impact on speech or hearing offering potential for inclusive PPE strategies #IDsky 📄: doi.org/10.1017/ice....

🆕 New in ICHE: A blood culture algorithm safely reduced unnecessary cultures in SOT recipients - 25% were inappropriate, none missed true infections. Findings support expanding diagnostic stewardship #IDSky 📄: doi.org/10.1017/ice....

🆕 New in ICHE: An EHR-based intervention reduced unnecessary testing & treatment for asymptomatic bacteriuria in older adults This approach shows promise in minimizing overtreatment and supporting antimicrobial stewardship #IDSky 📄: doi.org/10.1017/ice....

🆕 New from Branch-Elliman et al: 2-part series in ICHE on de-/implementation science to IP&C and ASP 📄 Part I: Life cycle of interventions on adoption to de-implementation 📄 Part II: A practical roadmap w/ real-world examples #IDSky Part I: doi.org/10.1017/ice.... Part II: doi.org/10.1017/ice....

Our new paper in @ichejournal.bsky.social: a cluster of healthcare-associated Burkholderia sola infections via WGS ➡️ B sola is a newly described BCC species ➡️ We detected 2 infxs via donor derived lung Tx + forward transmission #IDSky www.cambridge.org/core/journal...

🆕 New in ICHE: How did the COVID-19 pandemic impact HAIs and AMR in Canadian hospitals? 📈 This interrupted time series study (2018–2022) found significant increase in HAIs and AMR organisms following the onset of the pandemic #IDSky 📄: doi.org/10.1017/ice....

🆕 New in ICHE: Can far-UVC handheld devices improve disinfection of high-touch surfaces? Filtered 222 nm handheld UV device ⬇️ surface bacteria by up to 83% and genomic analysis identified MDROs persisting in the environment, underscoring both promise & limits #IDSky 📃: doi.org/10.1017/ice....

🆕 New in ICHE: Can mobile health tools engage patients in infection prevention? This study piloted an mHealth app in clinical settings to support hand hygiene, device care, and other practices with insights on feasibility, workflow, & barriers to adoption #IDSky 📄: doi.org/10.1017/ice....

🆕 New in ICHE: Can Enhanced Barrier Precautions reduce S. aureus and CRO transmission in nursing home ventilator units? A pre-post study of over 12,000 residents shows promise but persistent colonization and transmission remain challenges #IDSky 📄: doi.org/10.1017/ice....

🆕 New in ICHE: A mixed-methods study explores bias and discrimination experienced by antimicrobial stewards Findings highlight structural inequities and the need for improved support, recognition, and inclusion in stewardship roles. #IDsky 📄: doi.org/10.1017/ice....

🆕 New in ICHE: Case report of the 15th U.S. case of vancomycin-resistant Staphylococcus aureus (VRSA), identified in Michigan in 2021. Includes epidemiologic investigation and genomic analysis plus implications for IPC and antimicrobial stewardship. #IDSky 📄: doi.org/10.1017/ice....

TLDR; We propose an optimized ASE 2.0 definition: - allow POA infection diagnosis codes to anchor infection - include pts discharged alive on QAD 3 - include hypotension w/out pressors (>/= 2 readings in 6h) - include NIV or HFNC (>/= 2 days) - minor changes in Plt, Cr, and Tbili thresholds

🆕 New in ICHE: How should the CDC’s Adult Sepsis Event (ASE) definition evolve? This study modeled potential modifications and found tradeoffs between incidence, mortality, and clinical validity offering insight into how changes could shape surveillance #IDSky 📄: doi.org/10.1017/ice....

🆕 New in ICHE: Should hospital-onset bacteremia & fungemia (HOB) be a pay-for-performance measure? This pro/con debate explores whether HOB is preventable enough (and measurable enough) to drive accountability without unintended consequences #IDSky 📄: doi.org/10.1017/ice....

New Podcast Episode! @davidcalfeemd.bsky.social talks to Drs. Kaur, Uslan, & Yang on the clinical utility, benefits, and pitfalls of Plasma Cell-Free DNA and Metagenomic Sequencing! #IDSky 🟪: podcasts.apple.com/us/podcast/e... 🟧: soundcloud.com/user-6607204... 🟩: open.spotify.com/episode/7sV3...

🆕 New in ICHE: How does the new NHSN test method definition affect C. difficile reporting? Authors found that the 2024 update—focusing on a facility’s testing strategy (NAAT + toxin EIA)—improved model performance and reduced overestimation of hospital-onset CDI #IDSky 📄: doi.org/10.1017/ice....

🆕 New in ICHE: How much does HCW masking reduce SARS-CoV-2 transmission? Modeling study found that even moderate masking adherence by healthcare workers significantly reduces nosocomial COVID-19 especially at high community prevalence #IDSky 📄 doi.org/10.1017/ice....