@amyhcrockett.bsky.social @pamipenem.bsky.social: When selecting antibiotic regimens for conditions that have multiple appropriate regimens in guidelines, we should also consider the plastic waste--here is the example of chorioamnionitis. doi.org/10.1017/ash....

Low-resource interventions on susceptibility reporting can have an impact on antimicrobial prescribing for urinary tract infections. doi.org/10.1017/ash....

@priyanori.bsky.social @yiguoid.bsky.social et al: This study evaluated antibiotic use and appropriateness in HO-C. diff cases compared to matched controls in an inpatient setting at a NYC hospital. ⬆️ or inappropriate abx use was not associated with HO-C. diff infection doi.org/10.1017/ash....

Many Japanese regional hospitals lack ID specialists for ASPs. This study supported 9 hospitals, revealing barriers like poor collaboration & lack of standard procedures. A remote support model using implementation science to tailor interventions is proposed as a solution. doi.org/10.1017/ash....

Healthcare trainees born between 1999-2005 in our study had approximately 70% anti-HBs titers ≥10 mIU/mL, regardless of their reported vaccination history. However, one in four had titers below the protective threshold, despite self-reports of a complete vaccination schedule. doi.org/10.1017/ash....

@idatuic.bsky.social: During a national blood culture bottle shortage, UI Health implemented a stewardship intervention that safely ⬇️ blood culture utilization by 60% while maintaining stable sepsis outcomes, demonstrating the value of rapid, multidisciplinary stewardship. doi.org/10.1017/ash....

The implementation of an ASP in the pediatric ICUs of a Peruvian center was associated with a significant 12% reduction in average antibiotic consumption. These findings underscore the vital role of ASPs in fostering appropriate and rational antibiotic use.

Public health pharmacists identified key publications that advance antimicrobial stewardship (AS) implementation across care settings. This work highlights the role of public health in guiding AS efforts and promoting appropriate antibiotic use. doi.org/10.1017/ash....

Retrospective, single-center quality improvement study, which included a pre- and post-implementation analysis of a pharmacist-led anti-MRSA therapy bundle, we observed a notable increase in pharmacist interventions, with a high provider acceptance rate. doi.org/10.1017/ash....

This study from @bacil-kadi.bsky.social et al evaluated the impact of an antimicrobial stewardship bundle in the urgent care setting to further investigate how to more effectively practice stewardship in the outpatient setting. doi.org/10.1017/ash....

This study addresses the unintended consequences of China’s Volume-Based Procurement (VBP) policy on antimicrobial overuse by implementing a novel “dual-review mechanism” led by clinical pharmacists and infectious disease specialists. doi.org/10.1017/ash....

This multicenter cross-sectional study can help inform the approach to implementing universal respiratory virus admission testing should the need arise again in the future. doi.org/10.1017/ash....

This multicenter study highlights delays in blood culture positivity for Candida endocarditis and supports b-D-Glucan testing as a valuable tool for earlier diagnosis, especially in high-risk patients. Early detection aids timely antifungal treatment and improved outcomes. doi.org/10.1017/ash....

Few studies evaluate implementation of antimicrobial stewardship in rural settings. Tele-stewardship activities are likely to benefit outpatient rural settings, though further implementation research is needed. doi.org/10.1017/ash....

Patients discharged with surgical drains were interviewed to determine how the drains were managed and potential risk factors. Post-operative drain care instruction was revised as a result of differences identified between patients with SSI compared to those without SSI. doi.org/10.1017/ash....

National Healthcare Safety Network… we need to talk… doi.org/10.1017/ash....

We described the efficacy of decolonization treatments given in Hospital District of Southwest Finland (HDSWF). Of the patients successfully followed up, 78.3 % were decolonized. Decolonization treatment was effective in outpatient settings in our hospital district. doi.org/10.1017/ash....

Authors describe a machine learning model that uses structured data from the electronic health record to accurately stratify antibiotic necessity and appropriateness. doi.org/10.1017/ash....

Risk factors for surgical site infection following hysterectomy: nine-year experience at a large safety-net hospital network in New York City--is it really a good definition? doi.org/10.1017/ash....

@aprildyerid.bsky.social et al: A novel abx use denominator, targeted abx use admission, is defined as an inpt admission in which a select agent/group of agents is administered. Used in combo with length of therapy, it allows programs to quickly assess agent inpt durations. doi.org/10.1017/ash....

Fighting AntimicroBial Resistance in Carceral Settings (FABRICS) study on antibiotics prescribing in New England prisons--read on: doi.org/10.1017/ash....

The misuse of antibiotics in poultry farm worsens AMR. A survey in Enugu State found 90.5% used antibiotics, mainly for infections (80.5%) and growth (61%). Ampicillin (75%) was most used. Yet, 65% were unaware of AMR. Stricter regulations and education are needed. doi.org/10.1017/ash....

New on The ASHE Podcast! Dr. Brittany Rodriguez, Dr. Andrea Prinzi, and Dr. Denver Niles share key takeaways from the inaugural AMR Summit, held in November 2024, including rapid diagnostics, implementation science, and strategies for engaging hospital leadership. 🎧 Listen: bit.ly/46WUkP1

This study reveals high levels of multidrug-resistant bacterial contamination on surfaces in a Ugandan hospital mortuary. Findings highlight gaps in infection control practices and underscore the need for improved hygiene, disinfection, and antimicrobial stewardship. doi.org/10.1017/ash....

@ritikaprasad.bsky.social @stanfordasp.bsky.social @marisa-holubar.bsky.social: The inpatient mandatory indication field outperformed the ICD-10 in inferring dc abx indications, and can be used to assess abx appropriateness without needing manual chart review. doi.org/10.1017/ash....

A single-center study evaluated primary oral vancomycin prophylaxis in high-risk ICU patients during a Clostridioides difficile outbreak. Following implementation, HO-CDI rates declined without a notable increase in vancomycin-resistant enterococci. doi.org/10.1017/ash....

Antimicrobial optimization based on negative results from both BFP and respiratory culture may potentially reduce unnecessary antibiotic exposure and AKI in hospitalized patients with suspected pneumonia without increasing the risk of mortality and readmission. doi.org/10.1017/ash....

Across 3 facilities, 47% of high prescribers of broad-spectrum hospital-onset (BSHO) agents continued to prescribe high in the subsequent periods versus 24% for high anti-MRSA agents prescribers. Persistence of high prescribing adds credibility to our metric for BSHO agents doi.org/10.1017/ash....

First provision of a digital antibiotic allergy reassessment tool into patients medical record system in Germany--in surgical patients with reported allergy to beta-lactam-antibiotics. doi.org/10.1017/ash....

The study aimed to assess the implementation of antimicrobial stewardship (AMS) in the referral hospitals in the South West Region of Cameroon. The results showed 77% of activities were either fully or partially implemented, with 23% of the activities yet to be implemented. doi.org/10.1017/ash....

Building capacity for antimicrobial stewardship programs is crucial for improving patient outcomes and reducing resistance, but challenges can be difficult to overcome. This article highlights 8 pillars that have demonstrated to be successful for a large healthcare system. doi.org/10.1017/ash....

How can patients play a bigger role in infection care? Our study uncovers real stories and experiences from patients and healthcare professionals. Better participation means better outcomes—it's time to put patients at the centre of infection care. doi.org/10.1017/ash....

Infection prevention and control practices during the COVID-19 pandemic: impact on the prevalence of hospital-acquired infections in Tunisia doi.org/10.1017/ash....

A DC-area hospital saw a rise in hospital-acquired C. auris cases. A study identified environmental, clinical, and support-related factors contributing to this increase. Interventions like enhanced screening, isolation practices, & staff education helped reduce the case rate. doi.org/10.1017/ash....

This letter responds to Rowe et al.’s study on modified contact precautions for MDRO colonization, arguing that their findings support broader reform. It highlights patient safety, sustainability, and stewardship as reasons to reconsider routine gown use. doi.org/10.1017/ash....

A local guideline for the management of patients hospitalized with skin and soft tissue infections was implemented at an academic, safety-net hospital. Immediate reductions in use of broad-spectrum abx and durations of therapy were sustained over the subsequent 12 years. 😍 doi.org/10.1017/ash....

More on blood cx today: this retrospective analysis included 5,296 blood cx pairs and found that contamination rates were ⬆️ in blood cx with single-time stamps compared to blood cx with multiple-time stamps, although the difference did not reach statistical significance. doi.org/10.1017/ash....

Letter to the editors! Read all about blood culture stewardship--response doi.org/10.1017/ash.... to doi.org/10.1017/ash.... about doi.org/10.1017/ash....

Efficacy of an upper room ultraviolet-C (UV-C) technology versus far UV-C light technologies in reducing aerosolized bacteriophage MS2 doi.org/10.1017/ash....

Increased risk of Enterococcal bacteremia in critically ill patients with COVID-19 during pandemic surges ‼️ doi.org/10.1017/ash....

Antimicrobial stewardship (AMS) promotes responsible antibiotic use. Clinical decision support systems (CDSS) may support AMS by providing evidence-based recommendations, but effectiveness remains unclear. Implementation challenges and AI integration are key future focuses. doi.org/10.1017/ash....

Inappropriate outpatient prescribing for pharyngitis correlated with higher antibiotic utilization for respiratory conditions (AXR). doi.org/10.1017/ash....

From @ebhirsch.bsky.social; @morgan-bixby.bsky.social: Of 3072 urinalysis (UA) orders evaluated, only 30.1% reflexed to urine culture (UC). Less than half of UC reflexes resulted with observed high rates of ASB + ASB tx--onging diagnostic stewardship practices are needed. doi.org/10.1017/ash....

After implementation of an antibiotic IV to PO conversion protocol for pediatric Hematology-Oncology or Bone Marrow Transplant patients with bloodstream infections, 50.8% of eligible patients were changed to enteral therapy. Mortality and infection recurrence were stable. doi.org/10.1017/ash....

This retrospective cohort study demonstrates similar outcomes between oral antibiotic stepdown regimens to a continued course of IV therapy for uncomplicated streptococcal bloodstream infections, which may result in timelier transitions of care. doi.org/10.1017/ash....

Level of self-confidence among nurse practitioners in rural public health facilities regarding antimicrobial stewardship programs--from South Africa doi.org/10.1017/ash....

From the outpatient VA system--Variation in facility-level likelihood of drug-resistant Staphylococcus aureus in outpatients remains after patient-level risk adjustment doi.org/10.1017/ash....

@lisaidpharmd.bsky.social et al: Supportive care order sentence implementation within EHRs paired with provider education may be an effective, low-effort, outpatient stewardship practice to reduce unnecessary antibiotic prescribing for URI. doi.org/10.1017/ash....

Be inspired by this piece from Kristy Weinshel: "Everyone...is a patient or caregiver. Supporting the professionals who protect patients through infection prevention and stewardship makes this role feel mission-driven and deeply aligned with who I want to be as a leader." doi.org/10.1017/ash....

From @pamipenem.bsky.social @amyhcrockett.bsky.social et al: Small steps to make cumulative change--a summary of multiple QI interventions to improve abx prescribing in peripartum infections. doi.org/10.1017/ash....